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1. 发明授权

US06712859B2 Hernia repair prosthesis and methods for making same 有权
标题翻译：疝修补假体及其制作方法
公开(公告)号：US06712859B2
公开(公告)日：2004-03-30
申请号：US09894713
申请日：2001-06-28
申请人： Robert A. Rousseau , David Lindh
发明人： Robert A. Rousseau , David Lindh
IPC分类号： A61F204
CPC分类号： A61F2/0063 , A61B2017/00637
摘要： A hernia repair prosthesis with an occlusive member for inserting into and/or backing the herniated tissue. The occlusive member is convertible from a first configuration with a first axial length and first major radial extent to a second configuration with a second axial length and a second major radial extent. The second axial length is less than the first axial length and the second major radial extent is larger than the first major radial extent. The occlusive member has a pair of subsections, each having an apex, lands and pleats and each flaring outwardly therefrom towards a terminal end. The apexes are disposed at opposite ends of the occlusive member with the terminal ends overlapping. The pair of subsections are conjoined proximate the overlapping terminal ends. The terminal end of one or both of the subsections may be in the form of a conic flange mimicking the lands and pleats of the other subsection providing automatic alignment and nesting to aid in the attachment of the two subsections. In accordance with methods for forming the subsections, a surgical fabric is thermoset on a male die and may be stretched or heat shrunk to aid in conforming the surgical fabric to the contours of the male die. The subsections may be joined by ultrasound.
摘要翻译：具有用于插入和/或支撑突出的组织的闭塞构件的疝修补假体。闭合构件可从具有第一轴向长度和第一主要径向范围的第一构造转换成具有第二轴向长度和第二主要径向范围的第二构造。第二轴向长度小于第一轴向长度，第二主要径向范围大于第一主要径向范围。闭塞构件具有一对子部分，每个子部分具有顶点，平台和褶皱，并且每个部分从其向外朝向末端向外扩张。顶点设置在闭塞构件的相对端，终端重叠。一对子部分在重叠的终端附近相连。一个或两个子部分的终端可以是模仿其他子部分的脊和褶的圆锥法兰的形式，提供自动对准和嵌套以辅助两个子部分的附接。根据用于形成子部分的方法，手术织物在阳模上热固化，并且可以被拉伸或热收缩以帮助将外科织物与阳模的轮廓一致。子部分可以通过超声波连接。

2. 发明授权

US06676701B2 Micro-porous mesh stent with hybrid structure 有权
标题翻译：具有混合结构的微孔网支架
公开(公告)号：US06676701B2
公开(公告)日：2004-01-13
申请号：US09929474
申请日：2001-08-13
申请人： Jonathan M. Rourke , Yi Yang
发明人： Jonathan M. Rourke , Yi Yang
IPC分类号： A61F204
CPC分类号： A61F2/01 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/92 , A61F2002/018 , A61F2210/0019 , A61F2220/005 , A61F2220/0058 , A61F2230/0006 , A61F2230/0069
摘要： A prosthesis for treating a body passage includes a micro-porous tubular element and a support element. The tubular element is formed from a thin-walled sheet having a wall thickness of 25 micrometers or less, preferably a coiled-sheet exhibiting temperature-activated shape memory properties. The mesh pattern includes a plurality of openings in the sheet having a maximum dimension of not more than about 200 micrometers, thereby acting as a filter trapping embolic material while facilitating endothelial growth therethrough. The support element includes a plurality of struts, preferably having a thickness of 100-150 micrometers. The support element is preferably an independent component from the tubular element. Alternatively, the support element may be attached to or integrally formed as part of the tubular element. The tubular and support elements are placed on a catheter in contracted conditions and advanced endoluminally to a treatment location within a body passage. The tubular element is deployed, and the support element is expanded to an enlarged condition at the treatment location to engage an interior surface of the tubular element, thereby securing the tubular element and holding the lumen of the treatment location open.
摘要翻译：用于治疗身体通道的假体包括微孔管状元件和支撑元件。管状元件由壁厚为25微米或更小的薄壁片形成，优选呈现温度激活形状记忆性的卷曲片。网格图案包括片材中的多个开口，其具有不大于约200微米的最大尺寸，从而用作过滤器捕获栓塞材料，同时促进通过其中的内皮生长。支撑元件包括多个支柱，优选具有100-150微米的厚度。支撑元件优选地是与管状元件独立的部件。或者，支撑元件可以作为管状元件的一部分附接或一体地形成。管状和支撑元件在收缩状态下放置在导管上，并且在体内通过内部处理位置进一步前进。管状元件被展开，并且支撑元件在治疗位置处被扩张到扩大的状态以接合管状元件的内表面，由此固定管状元件并将治疗位置的内腔保持打开。

3. 发明授权

US06613095B1 Prosthesis for continuous internal peritoneal dialysis and continuous method of providing peritoneal dialysis 失效
标题翻译：连续腹膜透析假体和连续腹膜透析法
公开(公告)号：US06613095B1
公开(公告)日：2003-09-02
申请号：US09693591
申请日：2000-10-20
申请人： John M. Levin
发明人： John M. Levin
IPC分类号： A61F204
CPC分类号： A61M1/1678 , A61M1/28 , A61M1/284 , A61M1/285 , A61M2205/04
摘要： Continuous internal peritoneal dialysis prosthesis and method employing an abdominal sac adapted to be retained in the abdominal region of a patient's body and including dialyzate therein for permitting unconcentrated urine within the peritoneal region to pass through a semi-permeable membrane wall of the abdominal sac. The unconcentrated urine within the abdominal sac is directed through a section of the patient's bowel and is communicated with the internal wall of the bowel to thereby concentrate the urine. The concentrated urine is then directed into the urinary bladder for subsequent excretion from the patient's body. In the preferred prosthesis and method of this invention the normal breathing pattern of the patient is employed to assist in the circulation of the unconcentrated urine from the abdominal sac into and through the section of the patient's bowel. In alternative embodiments, the dialyzate may be contained within the abdominal sac, contained within the prosthesis, or allowed to directly contact the peritoneum.
摘要翻译：连续腹膜内透析假体和采用适于保留在患者体内腹部区域的腹囊的方法，包括透析液，以使腹膜区域内的非浓缩尿液通过腹囊的半透膜壁。腹囊内的未浓缩的尿被引导通过患者肠的一部分并与肠内壁连通，从而集中尿液。然后将浓缩的尿液导入膀胱，以便随后从患者体内排出。在本发明的优选的假体和方法中，使用患者的正常呼吸模式来帮助将不浓缩的尿从腹囊循环进入并穿过患者肠的部分。在替代实施方案中，透析液可以包含在包含在假体内的腹囊内，或允许直接接触腹膜。

4. 发明授权

US06544291B2 Sutureless gastroesophageal anti-reflux valve prosthesis and tool for peroral implantation thereof 失效
标题翻译：无缝合胃食道反流阀门假体及其手术用于口腔植入
公开(公告)号：US06544291B2
公开(公告)日：2003-04-08
申请号：US09681364
申请日：2001-03-26
申请人： Thomas V. Taylor
发明人： Thomas V. Taylor
IPC分类号： A61F204
CPC分类号： A61F2/0004 , A61F2/02 , A61F2/24 , A61F2002/044
摘要： Disclosed are an instrument, valve prosthesis and procedure for the minimally invasive implantation of a sutureless anti-reflux valve in a patient for the treatment of gastroesophageal reflux disease. A prosthesis is provided that comprises a cylindrical housing, a mounting ring and a one-way anti-reflux valve depending from the mounting ring. The cylindrical housing is constructed of a memory material that can be fixed in the gastroesophageal junction. The mounting ring and the anti-reflux valve are fixed within the housing.
摘要翻译：公开了一种用于在患者中微创植入无缝合抗反流阀用于治疗胃食管反流病的器械，瓣膜假体和程序。提供了一种假体，其包括圆柱形壳体，安装环和从安装环悬挂的单向抗回流阀。圆柱形壳体由可以固定在胃食管交界处的记忆材料构成。安装环和防回流阀固定在外壳内。

5. 发明授权

US06432040B1 Implantable esophageal sphincter apparatus for gastroesophageal reflux disease and method 失效
标题翻译：用于胃食管反流病的植入式食管括约肌器及其方法
公开(公告)号：US06432040B1
公开(公告)日：2002-08-13
申请号：US09661978
申请日：2000-09-14
申请人： Nizam N. Meah
发明人： Nizam N. Meah
IPC分类号： A61F204
CPC分类号： A61F5/0053 , A61F2/004
摘要： An implantable esophageal sphincter apparatus with an adjustable band to be placed at the lower part of the esophagus. The inflation of the band, or sphincter body, can be increased or decreased to adjust the tightness of the device. The inflatable sphincter body may be wrapped around the esophagus and may be connected to an inflation device with a fluid reservoir. The inflation device may have a pump mechanism that will respond to external control to increase or decrease the inflation of the sphincter body. The sphincter apparatus will be held in place at the area of implantation by sutures and by fenestration mechanisms, which will allow ingrowths of tissue or fibrous elements of the body around the sphincter apparatus or into porous materials on the sphincter apparatus. The apparatus may also include a circumferential shield on a distal side of the sphincter apparatus. The shield is adapted to fit against the distal or lower side of the patient's diaphragm and inhibits the development of a hiatus hernia, that is, a protrusion of the stomach past the diaphragm through the passage for the esophagus.
摘要翻译：可植入食管括约肌设备，可放置在食管下部。可以增加或减少带状物或括约肌体的膨胀以调节装置的紧密度。可充气的括约肌体可以缠绕在食道周围，并且可以连接到具有流体储存器的充气装置。充气装置可以具有泵机构，其将响应于外部控制以增加或减少括约肌体的膨胀。括约肌装置将通过缝合线和开窗机构在植入区域保持就位，这将允许括约肌装置周围的组织或纤维元件的向内生长或括约肌装置上的多孔材料。该装置还可以包括在括约肌装置的远侧上的周边屏蔽。护罩适于与患者隔膜的远侧或下侧相配合，并且抑制间隙性疝的发展，即胃通过隔膜通过隔膜的突起。

6. 发明授权

US06224540B1 Passive girdle for heart ventricle for therapeutic aid to patients having ventricular dilatation 失效
标题翻译：用于心室的被动腰带用于对患有心室扩张的患者的治疗辅助
公开(公告)号：US06224540B1
公开(公告)日：2001-05-01
申请号：US09023592
申请日：1998-02-13
申请人： David M. Lederman , Robert T. V. Kung
发明人： David M. Lederman , Robert T. V. Kung
IPC分类号： A61F204
CPC分类号： A61F2/2481 , A61F2002/0068 , A61M1/1008 , A61M1/1044 , A61M1/106 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M2205/33 , A61M2205/3303 , Y10S623/904
摘要： A passive girdle is wrapped around a heart muscle which has dilatation of a ventricle to conform to the size and shape of the heart and to constrain the dilatation during diastole. The girdle is formed of a material and structure that does not expand away from the heart but may, over an extended period of time be decreased in size as dilatation decreases.
摘要翻译：被动腰带缠绕在具有心室扩张的心脏肌肉中以符合心脏的大小和形状并且限制舒张期间的扩张。腰带由不会从心脏扩张的材料和结构形成，但是随着扩张减小，延长的时间段可以减小尺寸。

7. 发明授权

US06743259B2 Lung assist apparatus and methods for use 失效
公开(公告)号：US06743259B2
公开(公告)日：2004-06-01
申请号：US09922344
申请日：2001-08-03
申请人： Richard S. Ginn
发明人： Richard S. Ginn
IPC分类号： A61F204
CPC分类号： A61F2/04 , A61F2/00 , A61F2/07 , A61F2/24 , A61F2/852 , A61F2002/043 , A61F2002/065 , A61F2002/821 , A61F2250/0063 , A61M16/0406
摘要： A lung-assist apparatus includes a tubular housing, a tubular nozzle therein, and a first valve disposed between the housing and nozzle. The housing is implanted across a bifurcation such that the nozzle extends from a first branch communicating with a healthy region of a lung towards a main passage, and terminates proximate a lateral opening in the housing that is disposed within a second branch communicating with a damaged region of the lung. During inhalation, the first valve opens to allow air flow into the first branch, and closes during exhalation to force air through the nozzle, thereby inducing a vacuum for drawing air from the damaged region. A second valve in the second branch opens during exhalation to draw air from the diseased region, and closes during inhalation to prevent air from being drawn into the damaged region.

8. 发明授权

US06709465B2 Radially expanding ureteral device 失效
标题翻译：径向扩张输尿管装置
公开(公告)号：US06709465B2
公开(公告)日：2004-03-23
申请号：US09755487
申请日：2001-01-05
申请人： Michael Edward Mitchell , Gloria Miran Ro , Aoy Tomita
发明人： Michael Edward Mitchell , Gloria Miran Ro , Aoy Tomita
IPC分类号： A61F204
CPC分类号： A61F2/94 , A61F2/07 , A61F2/91 , A61F2210/0004 , A61F2230/0039 , A61F2230/005 , A61F2230/0058 , A61F2230/0071 , A61F2230/0076 , A61M27/008 , A61M29/02 , A61M2210/1089
摘要： A ureteral device is provided for facilitating stone passage through a ureter or duct. An exemplary ureteral device includes a flexible, elongate body that defines a plurality of cages along the body. In a contracted state the cages have a reduced diameter. When an activation force is applied, the cages transform to an expanded state, thereby defining a plurality of void spaces. The void spaces are configured to receive an obstruction, such as a stone. The ureteral device can then be induced to the contracted state to compress the obstruction within the elongate, flexible body and then be removed from the obstructed passage. The ureteral device can be configured to have different numbers of elongate flexible members that define the cages.
摘要翻译：输尿管装置用于促进石块通过输尿管或管道。示例性输尿管装置包括沿主体限定多个笼的柔性细长体。在承包状态下，笼子的直径减小。当施加激活力时，保持架转换到展开状态，从而限定多个空隙。空隙空间被配置成接收诸如石头的障碍物。然后可以将输尿管装置诱导到收缩状态以压缩细长的柔性体内的阻塞物，然后从阻塞的通道中移除。输尿管装置可被配置成具有不同数量的限定笼子的细长柔性构件。

9. 发明授权

US06702732B1 Expandable cardiac harness for treating congestive heart failure 失效
公开(公告)号：US06702732B1
公开(公告)日：2004-03-09
申请号：US09634043
申请日：2000-08-08
申请人： Lilip Lau , Bill Hartigan
发明人： Lilip Lau , Bill Hartigan
IPC分类号： A61F204
CPC分类号： A61F2/2481 , A61F2002/2484 , A61M1/1001 , A61M1/1003 , A61M1/1008 , A61M1/1046 , A61M1/1048 , A61M1/1056 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/33 , A61M2205/3303 , A61M2205/3523 , A61M2205/8206 , A61M2205/8243
摘要： A cardiac harness for treating congestive heart failure is disclosed. The harness applies elastic, compressive reinforcement on the left ventricle to reduce deleterious wall tension and to resist shape change of the ventricle during the mechanical cardiac cycle. Rather than imposing a dimension beyond which the heart cannot expand, the harness provides no hard limit over the range of diastolic expansion of the ventricle. Instead, the harness follows the contour of the heart throughout diastole and continuously exerts gentle resistance to stretch. Also disclosed is a method of delivering the cardiac harness to the heart minimally invasively.

10. 发明授权

US06682474B2 Expandable cardiac harness for treating congestive heart failure 失效
公开(公告)号：US06682474B2
公开(公告)日：2004-01-27
申请号：US09952081
申请日：2001-09-10
申请人： Lilip Lau , Bill Hartigan
发明人： Lilip Lau , Bill Hartigan
IPC分类号： A61F204
CPC分类号： A61F2/2481 , A61F2002/0072 , A61F2002/2484 , A61M1/1003 , A61M1/1008 , A61M1/1046 , A61M1/1048 , A61M1/1056 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/0266 , A61M2205/33 , A61M2205/3303 , A61M2205/3523 , A61M2205/8206 , A61M2205/8243 , A61N1/0587 , A61N1/3627 , Y10T29/49995
摘要： A cardiac harness for treating congestive heart failure is disclosed. The harness applies elastic, compressive reinforcement on the left ventricle to reduce deleterious wall tension and to resist shape change of the ventricle during the mechanical cardiac cycle. Rather than imposing a dimension beyond which the heart cannot expand, the harness provides no hard limit over the range of diastolic expansion of the ventricle. Instead, the harness follows the contour of the heart throughout diastole and continuously exerts gentle resistance to stretch. Also disclosed is a method of delivering the cardiac harness to the heart minimally invasively.

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