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1. 发明授权

US09724196B2 Annuloplasty Ring Holder 有权
公开(公告)号：US09724196B2
公开(公告)日：2017-08-08
申请号：US14853846
申请日：2015-09-14
申请人： Medtronic, Inc.
发明人： John T. M. Wright , Hieu Cong Nguyen
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61F2/2445 , A61F2240/001 , Y10S623/904
摘要： An annuloplasty ring holder including a head having an upper surface and an annuloplasty ring receiving surface facing opposite the upper surface. The annuloplasty ring holder also includes means for attaching an annuloplasty ring to the annuloplasty ring receiving surface. The means for attaching an annuloplasty ring to the annuloplasty ring receiving surface may include one or more suture guides operatively associated with the head and configured to position one or more sutures to removably associate an annuloplasty ring with the annuloplasty ring receiving surface. The head may include a central hub and more than one spoke radiating out from the central hub. If the head is thus configured, each spoke will include a portion of the annuloplasty ring receiving surface.

2. 发明申请

US20160324634A1 METHOD FOR IMPLANTATION OF A HEART VALVE PROSTHESIS 审中-公开
标题翻译：用于植入心脏瓣膜的方法
公开(公告)号：US20160324634A1
公开(公告)日：2016-11-10
申请号：US15214261
申请日：2016-07-19
申请人： Edwards Lifesciences CardiAQ LLC
发明人： Shlomo Gabbay
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2/2475 , A61F2210/0014 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0078 , G01N2800/52 , Y10S623/904
摘要： A method for implanting a heart valve into a patient's heart can include securing the heart valve prosthesis to a distal portion of an implanter apparatus. An opening is created in muscle tissue of the patient's heart, through which a length of the barrel is inserted such that an end of the barrel is advanced toward the implantation site. The heart valve prosthesis is advanced through the barrel to the implantation site. The heart valve prosthesis is positioned at the desired implantation site. The heart valve prosthesis can be expanded at the desired implantation site to anchor the prosthesis into adjacent tissue.
摘要翻译：将心脏瓣膜植入患者心脏的方法可以包括将心脏瓣膜假体固定到植入装置的远侧部分。在患者心脏的肌肉组织中产生开口，通过该开口插入桶的长度，使得筒的端部朝向植入部位前进。心脏瓣膜假体通过镜筒前进到植入部位。心脏瓣膜假体位于所需的植入部位。可以在期望的植入部位扩张心脏瓣膜假体以将假体锚固到相邻的组织中。

3. 发明申请

US20160317793A1 CONDUIT DEVICE AND SYSTEM FOR IMPLANTING A CONDUIT DEVICE IN A TISSUE WALL 有权
标题翻译：用于将组装墙壁中的导管装置嵌入的导管装置和系统
公开(公告)号：US20160317793A1
公开(公告)日：2016-11-03
申请号：US15058703
申请日：2016-03-02
申请人： Emory University , Georgia Tech Research Corporation
发明人： Thomas A. Vassiliades , Ajit Yoganathan , Jorge Hernan Jimenez
IPC分类号： A61M27/00 , A61M1/10 , A61B17/3205
CPC分类号： A61M27/002 , A61B17/11 , A61B17/32053 , A61B2017/00123 , A61B2017/00243 , A61B2017/00252 , A61B2017/3488 , A61B2018/00351 , A61B2018/00392 , A61F2/064 , A61M1/10 , A61M1/1008 , A61M1/12 , A61M1/122 , A61M2210/1085 , A61M2210/125 , Y10S623/904
摘要： Various embodiments of the present invention provide a conduit device including an attaching device configured for defining a helical pathway through a tissue wall and complementary ring in cooperation for securing the device within an aperture defined in the tissue wall. Some embodiments of the present invention further provide a system for implanting a conduit device in a tissue wall. More specifically, some embodiments provide a system including a coring device for defining an aperture in a tissue by removing and retaining a tissue core and securely implanting a conduit device therein so as to provide fluid communication between a first and second surface of the tissue wall via the conduit device.
摘要翻译：本发明的各种实施例提供了一种管道装置，其包括附接装置，该附接装置构造成用于通过组织壁和互补环限定螺旋路径，用于将装置固定在限定在组织壁中的孔内。本发明的一些实施例还提供了一种用于在组织壁中植入导管装置的系统。更具体地，一些实施例提供一种系统，其包括用于通过去除和保持组织芯并在其中牢固地注入导管装置来限定组织中的孔的取心装置，以便在组织壁的第一和第二表面之间提供流体连通导管装置。

4. 发明授权

US09138313B2 Percutaneous aortic valve 有权
标题翻译：经皮主动脉瓣
公开(公告)号：US09138313B2
公开(公告)日：2015-09-22
申请号：US13449618
申请日：2012-04-18
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2412 , A61B2017/00243 , A61F2/2421 , A61F2/2436 , A61F2230/0091 , Y10S623/904
摘要： A method of minimally invasively replacing a cardiac valve of a patient including inserting a delivery catheter intraluminally, inserting a valve resecting instrument intraluminally through the delivery catheter to a position adjacent the cardiac valve of a patient, manipulating the valve resecting instrument to resect the cardiac valve, removing the resected valve through the delivery catheter, and providing a delivery instrument having a replacement valve contained therein. The delivery instrument is advanced into the delivery catheter and intraluminally so that a distal end portion of the instrument is adjacent an annulus of a patient, and a first portion of the valve is exposed from the delivery instrument to position it on a first side of the annulus, and thereafter a second portion of the valve is exposed to position it on a second side of the annulus.
摘要翻译：一种最小限度地侵入性地替换患者的心脏瓣膜的方法，包括内窥镜插入输送导管，通过输送导管将瓣膜切除仪器内窥镜插入到与患者的心脏瓣膜相邻的位置，操纵瓣膜切除器械切除心脏瓣膜通过输送导管去除切除的瓣膜，并提供其中包含置换瓣膜的输送器械。输送器械被推进到输送导管中并且在腔内进行，使得器械的远端部分邻近患者的环带，并且阀的第一部分从输送器械暴露以将其定位在患者的第一侧环，然后将阀的第二部分暴露以将其定位在环的第二侧上。

5. 发明授权

US09095432B2 Collapsible prosthetic valve having an internal cover 有权
标题翻译：具有内盖的可折叠假体瓣
公开(公告)号：US09095432B2
公开(公告)日：2015-08-04
申请号：US14089332
申请日：2013-11-25
申请人： Edwards Lifesciences PVT, Inc.
发明人： Alain Cribier
IPC分类号： A61F2/24 , A61B19/00
CPC分类号： A61F2/2409 , A61B90/39 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/2475 , A61F2220/0008 , A61F2230/0054 , A61F2230/0069 , A61F2250/006 , Y10S623/90 , Y10S623/904
摘要： A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
摘要翻译：提供了一种用于植入狭窄主动脉瓣的人工瓣膜。假体瓣膜包括径向可折叠的框架，其被配置为使用导管插入技术来推进患者的脉管系统。可折叠的瓣结构缝合到框架上，以允许血液在一个方向上流动。内部盖沿框架的内表面延伸。内盖形成位于框架的下端与阀瓣结构之间的管状套管。内盖防止血液通过框架的杆之间的空间。将内盖的上端缝合到瓣膜结构。内盖优选由心包制成。

6. 发明授权

US09066799B2 Prosthetic valve for transluminal delivery 有权
标题翻译：用于经腔输送的假体瓣膜
公开(公告)号：US09066799B2
公开(公告)日：2015-06-30
申请号：US13010010
申请日：2011-01-20
申请人： Jacques Seguin , Georg Börtlein
发明人： Jacques Seguin , Georg Börtlein
IPC分类号： A61F2/24 , A61B17/02
CPC分类号： A61F2/2436 , A61B17/0218 , A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2210/0023 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0003 , A61F2250/0039 , A61F2250/0048 , A61F2250/0069 , Y10S623/904
摘要： A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.
摘要翻译：一种用于替换缺陷天然瓣膜的人工瓣膜组件包括支撑在可扩张瓣膜支架上的置换瓣膜。如果需要，可以使用一个或多个锚。完全支撑瓣膜环，瓣膜小叶和瓣膜关节点的瓣膜支撑件被构造为可折叠的，用于经腔输送，并且当组件被适当定位时，其可扩张以接触天然瓣膜的解剖环。当膨胀时，锚固件接合管腔壁，并且当定位就位时防止阀组件的大量迁移。假体瓣膜组件围绕导管可压缩，并且被外护套限制为扩张。导管可以插入体内的腔内，例如股动脉，并且被输送到期望的位置，例如心脏。当外鞘缩回时，假体瓣膜组件膨胀到扩张位置，使得瓣膜和瓣膜支撑件在缺陷的天然瓣膜内膨胀，并且锚固件与腔壁接合。

7. 发明申请

US20150139911A1 PREVENTION OF MYOCARDIAL INFARCTION INDUCED VENTRICULAR EXPANSION AND REMODELING 审中-公开
标题翻译：预防心肌梗塞引起的心室扩张和重建
公开(公告)号：US20150139911A1
公开(公告)日：2015-05-21
申请号：US14560588
申请日：2014-12-04
申请人： Cormend Technologies, LLC
发明人： William P. Santamore , Jeanne M. Lesniak
IPC分类号： A61K9/14 , A61K47/42 , A61K49/04 , A61K47/02 , A61K49/00
CPC分类号： A61K38/1841 , A61B17/00234 , A61B17/00491 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/3468 , A61B18/1815 , A61B2017/00243 , A61B2017/00247 , A61B2017/00862 , A61B2017/0404 , A61B2017/0412 , A61B2017/0422 , A61B2017/0427 , A61B2017/0437 , A61B2017/044 , A61B2017/0443 , A61B2017/0464 , A61B2017/048 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2018/00392 , A61F2/2451 , A61F2/2493 , A61F2002/249 , A61K9/0024 , A61K9/14 , A61K47/02 , A61K47/42 , A61K49/0013 , A61K49/04 , A61M25/09 , Y10S623/904
摘要： A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes identifying a target region of the myocardium and applying material directly and substantially only to at least a portion of the myocardial tissue of the target region. The material applied results in a physically modification the mechanical properties, including stiffness, of said tissue. Various devices and modes of practicing the method are disclosed for stiffening, restraining and constraining myocardial tissue for the treatment of conditions including myocardial infarction or mitral valve regurgitation.
摘要翻译：用于在具有病理状态的心脏的局部区域中直接治疗心肌组织的方法。该方法包括鉴定心肌的靶区域，并且直接且基本上只施加至目标区域的心肌组织的至少一部分。施加的材料导致物理地改变所述组织的机械性能，包括刚度。公开了实施该方法的各种装置和方式，用于加强，约束和约束心肌组织用于治疗包括心肌梗死或二尖瓣反流的病症。

8. 发明授权

US08784482B2 Method of reshaping a heart valve annulus using an intravascular device 有权
标题翻译：使用血管内装置重新形成心脏瓣膜环的方法
公开(公告)号：US08784482B2
公开(公告)日：2014-07-22
申请号：US10846850
申请日：2004-05-14
申请人： David A. Rahdert , Timothy R. Machold , John A. Macoviak , Robert T. Chang
发明人： David A. Rahdert , Timothy R. Machold , John A. Macoviak , Robert T. Chang
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2445 , A61B17/00234 , A61B17/0401 , A61B17/064 , A61B2017/00243 , A61B2017/00783 , A61B2017/00876 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/0419 , A61B2017/0427 , A61B2017/0437 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2002/30079 , A61F2210/009 , Y10S623/904
摘要： Devices, systems, and methods employ an implant that is sized and configured to attach in, on, or near the annulus of a dysfunctional heart valve. In use, the implant extends either across the minor axis of the annulus, or across the major axis of the annulus, or both. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets, which, in turn, reduces retrograde flow or regurgitation.
摘要翻译：装置，系统和方法采用植入物，其尺寸和构造适于附着在功能不全的心脏瓣膜的环中，附近或附近。在使用中，植入物延伸穿过环的短轴，或跨越环的主轴，或两者延伸。植入物恢复到心脏瓣膜环，并具有更多功能的解剖形状和张力。功能更多的解剖形状和张力有利于小叶的接合，这又降低逆行流动或反流。

9. 发明申请

US20140100652A1 ATTACHMENT DEVICE AND METHODS OF USING THE SAME 审中-公开
标题翻译：附件装置及其使用方法
公开(公告)号：US20140100652A1
公开(公告)日：2014-04-10
申请号：US14101233
申请日：2013-12-09
申请人： Medtronic, Inc.
发明人： Michael J. DREWS , Donnell W. Gurskis , Steven R. Bacich
IPC分类号： A61B17/064 , A61F2/24
CPC分类号： A61B17/064 , A61B17/0682 , A61B17/083 , A61B17/1227 , A61B2017/0641 , A61F2/2427 , Y10S623/904
摘要： Devices for attaching a first mass and a second mass and methods of making and using the same are disclosed. The devices can be made from an resilient, elastic or deformable materials. The devices can be used to attach a heart valve ring to a biological annulus. The devices can also be used for wound closure or a variety of other procedures such as anchoring a prosthesis to surrounding tissue or another prosthesis, tissue repair, such as in the closure of congenital defects such as septal heart defects, tissue or vessel anastomosis, fixation of tissue with or without a reinforcing mesh for hernia repair, orthopedic anchoring such as in bone fusing or tendon or muscle repair, ophthalmic indications, laparoscopic or endoscopic tissue repair or placement of prostheses, or use by robotic devices for procedures such as those above performed remotely.
摘要翻译：公开了用于附接第一质量块和第二质量块的装置及其制造和使用方法。设备可以由弹性，弹性或可变形材料制成。该装置可用于将心脏瓣膜环附接到生物环。该装置还可以用于伤口闭合或各种其他程序，例如将假体锚定到周围组织或另一假体，组织修复，例如闭合先天性缺陷，例如中隔心脏缺陷，组织或血管吻合，固定具有或不具有用于疝修补的加强网的组织，矫形锚固例如骨融合或肌腱或肌肉修复，眼科适应症，腹腔镜或内窥镜组织修复或假体放置，或由机器人装置用于上述方法远程

10. 发明申请

US20130218169A1 Conduit Device and System for Implanting a Conduit Device in a Tissue Wall 有权
标题翻译：用于在组织壁中植入导管装置的导管装置和系统
公开(公告)号：US20130218169A1
公开(公告)日：2013-08-22
申请号：US13845960
申请日：2013-03-18
申请人： EMORY UNIVERSITY , GEORGIA TECH RESEARCH CORPORATION
发明人： Thomas A. Vassiliades , Ajit Yoganathan , Jorge Hernan Jimenez
IPC分类号： A61F2/06 , A61B17/3205
CPC分类号： A61M27/002 , A61B17/11 , A61B17/32053 , A61B2017/00123 , A61B2017/00243 , A61B2017/00252 , A61B2017/3488 , A61B2018/00351 , A61B2018/00392 , A61F2/064 , A61M1/10 , A61M1/1008 , A61M1/12 , A61M1/122 , A61M2210/1085 , A61M2210/125 , Y10S623/904
摘要： Various embodiments of the present invention provide a conduit device including an attaching device configured for defining a helical pathway through a tissue wall and complementary ring in cooperation for securing the device within an aperture defined in the tissue wall. Some embodiments of the present invention further provide a system for implanting a conduit device in a tissue wall. More specifically, some embodiments provide a system including a coring device for defining an aperture in a tissue by removing and retaining a tissue core and securely implanting a conduit device therein so as to provide fluid communication between a first and second surface of the tissue wall via the conduit device.
摘要翻译：本发明的各种实施例提供了一种管道装置，其包括附接装置，该附接装置构造成用于通过组织壁和互补环限定螺旋路径，用于将装置固定在限定在组织壁中的孔内。本发明的一些实施例还提供了一种用于在组织壁中植入导管装置的系统。更具体地，一些实施例提供一种系统，其包括用于通过去除和保持组织芯并在其中牢固地注入导管装置来限定组织中的孔的取心装置，以便在组织壁的第一和第二表面之间提供流体连通导管装置。

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