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1. 发明申请

US20110256171A1 NOVEL USE OF L. UNDULATA EXTRACT AS THERAPEUTICS FOR ALLERGIC DISEASES 有权
标题翻译：作为过敏性疾病的治疗药物的新鲜使用L.iiiii提取物
公开(公告)号：US20110256171A1
公开(公告)日：2011-10-20
申请号：US13170594
申请日：2011-06-28
申请人： Won-Kyo Jung , Il-Whan Choi , Se-Kwon Kim , Sung Su Yea , Yung Hyun Choi , Inhak Choi
发明人： Won-Kyo Jung , Il-Whan Choi , Se-Kwon Kim , Sung Su Yea , Yung Hyun Choi , Inhak Choi
IPC分类号： A61K36/04 , A61P17/00
CPC分类号： A61K36/04 , Y10S514/855
摘要： The present invention relates to a method of preventing or treating allergic diseases such as allergic rhinitis, atopic dermatitis, anaphylaxis, and asthma, which comprises administering an extract of Laurencia undulata in a therapeutically effective amount to a patient in need thereof.
摘要翻译：本发明涉及一种预防或治疗过敏性鼻炎，特应性皮炎，过敏反应和哮喘等过敏性疾病的方法，其包括以有效治疗有效量的治疗有效量施用万寿菊提取物。

2. 发明申请

US20050069585A1 Diphenhydramine tannate liquid and semi-solid compositions and methods of use 审中-公开
标题翻译：苯海拉明丹宁液体和半固体组合物和使用方法
公开(公告)号：US20050069585A1
公开(公告)日：2005-03-31
申请号：US10505355
申请日：2003-02-26
申请人： Jeffrey Kiel , H. Thomas , Narasimhan Mani
发明人： Jeffrey Kiel , H. Thomas , Narasimhan Mani
IPC分类号： A61K9/00 , A61K9/20 , A61K9/48 , A61K31/205 , A61K31/7024
CPC分类号： A61K31/205 , A61K9/007 , A61K9/2004 , A61K9/4858 , A61K9/4866 , A61K31/7024 , Y10S514/849 , Y10S514/85 , Y10S514/853 , Y10S514/855 , Y10S514/937
摘要： Pharmaceutical compositions consisting of diphenhydramine tannate which are effective when administered for the symptomatic relief of sneezing, itchy, watery eyes, itchy nose or throat and runny nose due to hay fever (allergic rhinitis) or other respiratory allergies are disclosed.
摘要翻译：公开了由喷雾，瘙痒，浑浊的眼睛，瘙痒的鼻子或喉咙症状缓解，由于花粉症（过敏性鼻炎）或其它呼吸道过敏引起的流鼻涕的症状缓解时，有效的苯海拉明酸鞣酸盐组成的药物组合物。

3. 发明申请

US20020193446A1 Compounds and methods for the inhibition of the expression of VCAM-1 失效
公开(公告)号：US20020193446A1
公开(公告)日：2002-12-19
申请号：US10114351
申请日：2002-04-02
发明人： Charles Q. Meng
IPC分类号： A61K031/10 , C07C323/16
CPC分类号： A61K31/222 , A61K31/225 , C07C323/20 , C07C323/21 , C07C323/25 , C07C323/56 , C07C323/66 , C07C323/67 , Y10S514/824 , Y10S514/825 , Y10S514/826 , Y10S514/855
摘要： This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.

4. 发明申请

US20020177717A1 Compounds and methods for the inhibition of the expression of VCAM-1 失效
标题翻译：用于抑制VCAM-1表达的化合物和方法
公开(公告)号：US20020177717A1
公开(公告)日：2002-11-28
申请号：US10060734
申请日：2002-01-30
发明人： Patricia K. Somers
IPC分类号： C07D213/46 , C07D213/63 , C07C323/22 , C07C229/38
CPC分类号： A61K31/222 , A61K31/225 , C07C323/20 , C07C323/21 , C07C323/25 , C07C323/56 , C07C323/66 , C07C323/67 , Y10S514/824 , Y10S514/825 , Y10S514/826 , Y10S514/855
摘要： This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.
摘要翻译：本发明涉及用于抑制VCAM-1表达的方法和组合物，特别是用于治疗由VCAM-1介导的疾病，包括心血管和炎性疾病。

5. 发明授权

US6015569A Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof 失效
标题翻译：多环芳族化合物及其组合的药物/化妆品组合物
公开(公告)号：US6015569A
公开(公告)日：2000-01-18
申请号：US971983
申请日：1997-11-17
申请人： Jean-Michel Bernardon
发明人： Jean-Michel Bernardon
IPC分类号： C07D333/38 , A61K8/00 , A61K8/06 , A61K8/14 , A61K8/18 , A61K8/19 , A61K8/25 , A61K8/30 , A61K8/33 , A61K8/36 , A61K8/362 , A61K8/368 , A61K8/37 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/49 , A61K8/67 , A61K8/72 , A61K31/06 , A61K31/085 , A61K31/12 , A61K31/135 , A61K31/19 , A61K31/22 , A61K31/255 , A61K31/38 , A61K31/381 , A61K31/44 , A61K45/06 , A61P9/00 , A61P11/00 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/08 , A61P17/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08 , C07C43/257 , C07C47/575 , C07C49/255 , C07C49/84 , C07C63/64 , C07C65/26 , C07C69/157 , C07C69/16 , C07C69/24 , C07C69/28 , C07C69/92 , C07C205/36 , C07C211/54 , C07C317/14 , C07C317/18 , C07C317/22 , C07C317/24 , C07C323/62 , C07D213/70 , C07D213/78 , C07D327/06 , C07D333/40 , A61K31/395
CPC分类号： A61Q5/12 , A61K45/06 , A61K8/33 , A61K8/368 , A61K8/445 , A61K8/46 , A61K8/466 , A61K8/4913 , A61K8/4926 , A61K8/4973 , A61K8/4986 , A61Q19/00 , A61Q5/00 , A61Q5/02 , Y10S514/844 , Y10S514/846 , Y10S514/855 , Y10S514/937 , Y10S514/944
摘要： Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(e): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.
摘要翻译：新型药物/化妆活性多环芳香族化合物具有结构式（I）：其中Ar是具有式（a） - （e）之一的基团：并且可用于治疗各种疾病状态，无论是否人或兽医，例如皮肤病学，风湿性，呼吸道，心血管和眼科疾病，以及用于治疗哺乳动物皮肤和毛发病症/病症。

6. 发明授权

US4927631A Decongestant preparation 失效
标题翻译：减充血剂制剂
公开(公告)号：US4927631A
公开(公告)日：1990-05-22
申请号：US311983
申请日：1989-02-16
申请人： Harry L. Bates
发明人： Harry L. Bates
IPC分类号： A61K36/15 , A61K36/185 , A61K36/61
CPC分类号： A61K36/15 , A61K36/185 , A61K36/61 , Y10S514/855 , Y10S514/969
摘要： A decongestant preparation is disclosed which comprises a set of active components and a petrolatum base wherein the active components consist essentially of menthol, camphor, eucalyptus oil, and spirits of turpentine, wherein the total concentration of the active components is no greater than about 1.0% by weight of the decongestant preparation, and wherein the set of active components consists essentially of in percent by weight from about 15 to about 25 menthol, from about 30 to about 40 camphor, from about 5 to about 10 eucalyptus oil, and from about 30 to about 40 spirits of turpentine, the decongestant being suitable for direct application to the nasal cavity.
摘要翻译：公开了一种减充血剂制剂，其包含一组活性组分和凡士林碱，其中活性组分基本上由薄荷醇，樟脑，桉树油和松节油精神组成，其中活性组分的总浓度不大于约1.0％，并且其中该组活性组分基本上由约15至约25薄荷醇，约30至约40樟脑，约5至约10桉树油和约30重量％的重量百分比组成至约40种松节油，减充血剂适用于直接应用于鼻腔。

7. 发明申请

US20080214660A1 Compounds and Methods for the Inhibition of the Expression of VCAM-1 审中-公开
标题翻译：抑制VCAM-1表达的化合物和方法
公开(公告)号：US20080214660A1
公开(公告)日：2008-09-04
申请号：US12121464
申请日：2008-05-15
申请人： Russell M. Medford , Patricia K. Somers , Lee K. Hoong , Charles O. Meng
发明人： Russell M. Medford , Patricia K. Somers , Lee K. Hoong , Charles O. Meng
IPC分类号： A61K31/341 , C07C61/16 , A61K31/192 , C07C69/00 , A61P19/02 , A61P29/00 , A61K31/216 , C07D307/02
CPC分类号： A61K31/222 , A61K31/225 , C07C323/20 , C07C323/21 , C07C323/25 , C07C323/56 , C07C323/66 , C07C323/67 , Y10S514/824 , Y10S514/825 , Y10S514/826 , Y10S514/855
摘要： This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.
摘要翻译：本发明涉及用于抑制VCAM-1表达的方法和组合物，特别是用于治疗由VCAM-1介导的疾病，包括心血管和炎性疾病。

8. 发明申请

US20050020509A1 Process for preparing tannate liquid and semi-solid dosage forms 有权
公开(公告)号：US20050020509A1
公开(公告)日：2005-01-27
申请号：US10921438
申请日：2004-08-19
申请人： Jeffrey Kiel , H. Thomas , Narasimhan Mani
发明人： Jeffrey Kiel , H. Thomas , Narasimhan Mani
IPC分类号： A61K9/00 , A61K9/20 , A61K9/48 , A61K31/205 , A61K31/7024 , C07H13/02
CPC分类号： A61K31/205 , A61K9/007 , A61K9/2004 , A61K9/4858 , A61K9/4866 , A61K31/7024 , Y10S514/849 , Y10S514/85 , Y10S514/853 , Y10S514/855 , Y10S514/937
摘要： An active ingredient from the group of an antihistamine, a decongestant, an antitussive or anticholinergic is dissolved in a suitable solvent and added to a dispersion of tannic acid in water to form the tannate salt complex of the active ingredient. The active ingredient tannate salt complex without isolation or purification is then added to a liquid or semi-solid medium composed of thickening, suspending, coloring, sweetening and flavoring agents, with stirring. Thereafter, preservatives, pH-adjusting and anti-caking agents in a suitable solvent are mixed with the liquid or semi-solid medium to generate a therapeutic dosage form.

9. 发明授权

US06602914B2 Compounds and methods for the inhibition of the expression of VCAM-1 失效
公开(公告)号：US06602914B2
公开(公告)日：2003-08-05
申请号：US10114346
申请日：2002-04-02
申请人： Charles Q. Meng
发明人： Charles Q. Meng
IPC分类号： A01N3100
CPC分类号： A61K31/222 , A61K31/225 , C07C323/20 , C07C323/21 , C07C323/25 , C07C323/56 , C07C323/66 , C07C323/67 , Y10S514/824 , Y10S514/825 , Y10S514/826 , Y10S514/855
摘要： This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.

10. 发明授权

US06548699B1 Compounds and methods for the inhibition of the expression of VCAM-1 失效
公开(公告)号：US06548699B1
公开(公告)日：2003-04-15
申请号：US09370046
申请日：1999-08-06
申请人： Patricia K. Somers
发明人： Patricia K. Somers
IPC分类号： C07C32100
CPC分类号： A61K31/222 , A61K31/225 , C07C323/20 , C07C323/21 , C07C323/25 , C07C323/56 , C07C323/66 , C07C323/67 , Y10S514/824 , Y10S514/825 , Y10S514/826 , Y10S514/855
摘要： This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.

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