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    • 1. 发明申请
    • Novel nucleotide sequences coding the citE gene
    • 编码citE基因的新型核苷酸序列
    • US20030113879A1
    • 2003-06-19
    • US09770688
    • 2001-06-06
    • Mike FarwickKlaus HuthmacherAchim MarxBrigitte BatheWalter Pfefferle
    • C12P013/08C12P013/04C12Q001/68C12N001/21
    • C12Y401/03006C12N9/88
    • The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide that is at least 70% identical with a polynucleotide that codes for a polypeptide containing the amino acid sequence of SEQ ID No. 2, b) polynucleotide that codes for a polypeptide containing an amino acid sequence that is at least 70% identical with the amino acid sequence of SEQ ID No. 2, c) polynucleotide that is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 consecutive nucleotides of the polynucleotide sequence of a), b) or c), and to a process for the production of L-amino acids by fermentation using coryneform bacteria in which at least the citE gene is present in attenuated form, and to the use of polynucleotides containing the sequences of the invention as hybridization probes.
    • 本发明涉及含有多核苷酸序列的多核苷酸序列,该多核苷酸序列选自a)与编码含有SEQ ID No.2的氨基酸序列的多肽的多核苷酸至少70%相同的多核苷酸,b)编码 对于含有与SEQ ID No.2的氨基酸序列至少70%相同的氨基酸序列的多肽,c)与a)或b)的多核苷酸互补的多核苷酸,以及d)至少含有 a),b)或c)的多核苷酸序列的15个连续核苷酸,以及通过发酵使用其中至少有citE基因以减毒形式存在的棒状细菌产生L-氨基酸的方法, 使用含有本发明序列的多核苷酸作为杂交探针。
    • 3. 发明申请
    • Novel nucleotide sequences coding for the citE gene
    • 编码citE基因的新型核苷酸序列
    • US20030157666A1
    • 2003-08-21
    • US10375355
    • 2003-02-28
    • Degussa AG
    • Mike FarwickKlaus HuthmacherAchim MarxBrigitte BatheWalter Pfefferle
    • C12P013/04C12Q001/68C07H021/04C12N009/88C12P021/02C12N001/21C12N015/74
    • C12Y401/03006C12N9/88
    • The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide that is at least 70% identical with a polynucleotide that codes for a polypeptide containing the amino acid sequence of SEQ ID No. 2, b) polynucleotide that codes for a polypeptide containing an amino acid sequence that is at least 70% identical with the amino acid sequence of SEQ ID No. 2, c) polynucleotide that is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 consecutive nucleotides of the polynucleotide sequence of a), b) or c), and to a process for the production of L-amino acids by fermentation using coryneform bacteria in which at least the citE gene is present in attenuated form, and to the use of polynucleotides containing the sequences of the invention as hybridization probes.
    • 本发明涉及含有多核苷酸序列的多核苷酸序列,该多核苷酸序列选自a)与编码含有SEQ ID No.2的氨基酸序列的多肽的多核苷酸至少70%相同的多核苷酸,b)编码 对于含有与SEQ ID No.2的氨基酸序列至少70%相同的氨基酸序列的多肽,c)与a)或b)的多核苷酸互补的多核苷酸,和d)至少含有 a),b)或c)的多核苷酸序列的15个连续核苷酸,以及通过发酵使用其中至少有citE基因以减毒形式存在的棒状细菌产生L-氨基酸的方法, 使用含有本发明序列的多核苷酸作为杂交探针。
    • 4. 发明授权
    • Nucleotide sequences coding for the citE gene
    • 编码citE基因的核苷酸序列
    • US07129066B2
    • 2006-10-31
    • US10375355
    • 2003-02-28
    • Mike FarwickKlaus HuthmacherAchim MarxBrigitte BatheWalter Pfefferle
    • Mike FarwickKlaus HuthmacherAchim MarxBrigitte BatheWalter Pfefferle
    • C12P13/08C12P13/04C12N9/88C07H21/04
    • C12Y401/03006C12N9/88
    • The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide that is at least 70% identical with a polynucleotide that codes for a polypeptide containing the amino acid sequence of SEQ ID No. 2, b) polynucleotide that codes for a polypeptide containing an amino acid sequence that is at least 70% identical with the amino acid sequence of SEQ ID No. 2, c) polynucleotide that is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 consecutive nucleotides of the polynucleotide sequence of a), b) or c), and to a process for the production of L-amino acids by fermentation using coryneform bacteria in which at least the citE gene is present in attenuated form, and to the use of polynucleotides containing the sequences of the invention as hybridization probes.
    • 本发明涉及含有多核苷酸序列的多核苷酸序列,该多核苷酸序列选自a)与编码含有SEQ ID No.2的氨基酸序列的多肽的多核苷酸至少70%相同的多核苷酸,b)编码 对于含有与SEQ ID No.2的氨基酸序列至少70%相同的氨基酸序列的多肽,c)与a)或b)的多核苷酸互补的多核苷酸,以及d)至少含有 a),b)或c)的多核苷酸序列的15个连续核苷酸,以及通过发酵使用其中至少有citE基因以减毒形式存在的棒状细菌产生L-氨基酸的方法, 使用含有本发明序列的多核苷酸作为杂交探针。