专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09328050B1 Processes for making hydroxymethylbenzoic acid compounds 有权
标题翻译：制备羟甲基苯甲酸化合物的方法
公开(公告)号：US09328050B1
公开(公告)日：2016-05-03
申请号：US14581369
申请日：2014-12-23
申请人： Eastman Chemical Company
发明人： Venkata Bharat Ram Boppana , Robert Thomas Hembre , Scott Donald Barnicki , Shane Kipley Kirk
IPC分类号： C07C51/347
CPC分类号： C07C51/347 , C07C51/367 , C07C65/01
摘要： This invention relates to hydrogenation processes for making hydroxymethylbenzoic acid compounds. More specifically, this invention relates to hydrogenation processes in the presence of tertiary amide solvent compounds, as well as compositions that can result from such processes. The invention thus provides processes for making hydroxymethylbenzoic acid compounds.
摘要翻译：本发明涉及制备羟甲基苯甲酸化合物的氢化方法。更具体地，本发明涉及在叔酰胺溶剂化合物存在下的氢化方法，以及可由此类方法产生的组合物。因此，本发明提供了制备羟甲基苯甲酸化合物的方法。

2. 发明申请

US20140364631A1 DIELS-ALDER REACTIONS CATALYZED BY LEWIS ACID CONTAINING SOLIDS: RENEWABLE PRODUCTION OF BIO-PLASTICS 有权
标题翻译：由含乳酸的固体催化的DIELS-ALDER反应：可再生产生物塑料
公开(公告)号：US20140364631A1
公开(公告)日：2014-12-11
申请号：US14282099
申请日：2014-05-20
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人： MARK E. DAVIS , JOSHUA PACHECO
IPC分类号： C07D493/08 , C07C2/86 , C07C67/00 , C07C29/44 , C07C51/353 , C07C45/68
CPC分类号： C07D493/08 , B01J29/0341 , B01J29/035 , B01J29/047 , B01J29/405 , B01J29/7057 , B01J29/89 , B01J2229/183 , C07C2/862 , C07C2/865 , C07C29/32 , C07C45/70 , C07C51/353 , C07C67/343 , C07C67/347 , C07C2529/00 , C07C2529/70 , C07C2529/89 , Y02P20/52 , C07C69/76 , C07C65/01 , C07C65/21 , C07C63/04 , C07C63/26 , C07C47/542 , C07C33/26 , C07C47/56 , C07C69/82 , C07C63/06 , C07C15/08
摘要： The present disclosure is related to silica-based Lewis acid catalysts, being essentially devoid of strong Brønsted acid character, and their ability to effect the [4+2] cycloaddition and dehydrative aromatization of dienes and dienophiles containing oxygenated substituents to form substituted benzene products. In some embodiments, the processes comprise contacting biomass-derived substrates with ethylene to form terephthalic acid and its derivatives.
摘要翻译：本公开涉及基本上没有强布朗斯台德酸性质的二氧化硅基路易斯酸催化剂，以及它们对含有氧化取代基的二烯和亲烯体的[4 + 2]环加成和脱水芳构化的能力，以形成取代的苯产物。在一些实施方案中，该方法包括使生物质衍生的底物与乙烯接触以形成对苯二甲酸及其衍生物。

3. 发明申请

US20080125604A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS 失效
公开(公告)号：US20080125604A1
公开(公告)日：2008-05-29
申请号：US11604942
申请日：2006-11-28
申请人： Joachim C. Ritter
发明人： Joachim C. Ritter
IPC分类号： C07C65/03 , C07C65/01
CPC分类号： C07C63/00 , C07C51/02 , C07C51/367 , C07C51/412 , C07C65/01 , C07C65/03 , C07C65/05 , C07C65/10
摘要： Hydroxy aromatic acids are produced in high yields and high purity (>95%) from halogenated aromatic acids in a reaction mixture containing a copper source and a ligand that coordinates to copper.

4. 发明授权

US07294722B2 Process for the synthesis of peptides containing a 4-hydroxy-proline substructure 有权
标题翻译：用于合成含有4-羟基 - 脯氨酸亚结构的肽的方法
公开(公告)号：US07294722B2
公开(公告)日：2007-11-13
申请号：US10538028
申请日：2003-12-11
申请人： Bernhard Wietfeld , Walter Prikoszovich , Bernhard Erb , Werner Pachinger
发明人： Bernhard Wietfeld , Walter Prikoszovich , Bernhard Erb , Werner Pachinger
IPC分类号： C07D207/12
CPC分类号： C07C51/15 , Y02P20/55 , C07C65/01
摘要： The present invention relates to processes for preparing peptides and to intermediates involved in such processes, e.g. a process for preparing a compound of formula VIII wherein R12 and R13 are as defined herein.
摘要翻译：本发明涉及制备涉及此类方法的肽和中间体的方法，例如，制备式VIII化合物的方法，其中R 12和R 13如本文所定义。

5. 发明授权

US4691043A Benzoic acid derivatives process for preparation and application as drugs, disinfectants or preservatives 失效
标题翻译：苯甲酸衍生物的制备和应用作为药物，消毒剂或防腐剂
公开(公告)号：US4691043A
公开(公告)日：1987-09-01
申请号：US816978
申请日：1986-01-07
申请人： Henri Demarne , Robert Filhol , Madeleine Mosse
发明人： Henri Demarne , Robert Filhol , Madeleine Mosse
IPC分类号： A23L3/34 , A01N37/36 , A01N37/40 , A01N39/00 , A23L3/3508 , A61K8/30 , A61K8/36 , A61K8/368 , A61K8/37 , A61K31/085 , A61K31/19 , A61K31/215 , A61K31/235 , A61P31/04 , A61Q5/02 , C07C33/20 , C07C51/00 , C07C51/08 , C07C65/01 , C07C65/21 , C07C67/00 , C07C69/757 , C07C69/76 , C07C69/78 , C07C69/92 , C07C205/19 , C07C205/37
CPC分类号： A61K31/235 , A01N37/36 , A01N39/00 , C07C205/19 , C07C205/37 , C07C255/00 , C07C33/20 , C07C65/01 , C07C65/21 , C07C69/78 , C07C69/92 , Y10S514/844 , Y10S514/846 , Y10S514/848 , Y10S514/861 , Y10S514/863 , Y10S514/886 , Y10S514/887 , Y10S514/969
摘要： Benzoic acid derivatives with the general formula: ##STR1## in which: A represents a straight or branched alkyl chain with 5 to 10 carbon atoms,X represents the oxygen atom or a direct bond,R represents hydrogen or an alkyl group with 2 to 6 carbon atoms, possibly substituted by an alcohol function,and the salts of the said derivatives.These derivatives display antimicrobial activity and are suitable as antiseptics, disinfectants and preservatives, particularly in the fields of pharmaceuticals, cosmetology and agri-foodstuffs.
摘要翻译：具有以下通式的苯甲酸衍生物：其中：A表示具有5至10个碳原子的直链或支链烷基链，X表示氧原子或直接键合，R表示氢或烷基，可能被醇官能取代的2至6个碳原子，以及所述衍生物的盐。这些衍生物显示出抗菌活性，并且适合作为防腐剂，消毒剂和防腐剂，特别是在药物，美容和农产品领域。

6. 发明授权

US4584397A Protease inhibitors 失效
公开(公告)号：US4584397A
公开(公告)日：1986-04-22
申请号：US664447
申请日：1984-10-24
申请人： Richard A. Mueller , Richard A. Partis
发明人： Richard A. Mueller , Richard A. Partis
IPC分类号： C07C65/01 , C07C65/19 , C07C65/40 , C07D295/02 , C07D295/03 , C07C69/76
CPC分类号： C07D295/03 , C07C65/01 , C07C65/19 , C07C65/40
摘要： This invention relates to methods of preventing or reducing the degradation of elastin and other proteins and thereby preventing or retarding the disease states caused by said degradation by administering compounds of the formula: ##STR1## or their pharmacologically acceptable salts.

7. 发明申请

US20150141670A1 DIELS-ALDER REACTIONS CATALYZED BY LEWIS ACID CONTAINING SOLIDS: RENEWABLE PRODUCTION OF BIO-PLASTICS 审中-公开
标题翻译：由含乳酸的固体催化的DIELS-ALDER反应：可再生产生物塑料
公开(公告)号：US20150141670A1
公开(公告)日：2015-05-21
申请号：US14561351
申请日：2014-12-05
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人： MARK E. DAVIS , JOSHUA J. PACHECO
IPC分类号： C07D493/08
CPC分类号： C07D493/08 , B01J29/0341 , B01J29/035 , B01J29/047 , B01J29/405 , B01J29/7057 , B01J29/89 , B01J2229/183 , C07C2/862 , C07C2/865 , C07C29/32 , C07C45/70 , C07C51/353 , C07C67/343 , C07C67/347 , C07C2529/00 , C07C2529/70 , C07C2529/89 , Y02P20/52 , C07C69/76 , C07C65/01 , C07C65/21 , C07C63/04 , C07C63/26 , C07C47/542 , C07C33/26 , C07C47/56 , C07C69/82 , C07C63/06 , C07C15/08
摘要： The present disclosure is related to silica-based Lewis acid catalysts, being essentially devoid of strong Brønsted acid character, and their ability to effect the [4+2] cycloaddition and dehydrative aromatization of dienes and dienophiles containing oxygenated substituents to form substituted benzene products. In some embodiments, the processes comprise contacting biomass-derived substrates with ethylene to form terephthalic acid and its derivatives.
摘要翻译：本公开涉及基本上没有强布朗斯台德酸性质的二氧化硅基路易斯酸催化剂，以及它们对含有氧化取代基的二烯和亲烯体的[4 + 2]环加成和脱水芳构化的能力，以形成取代的苯产物。在一些实施方案中，该方法包括使生物质衍生的底物与乙烯接触以形成对苯二甲酸及其衍生物。

8. 发明申请

US20140243278A1 Acid Addition Salt of Donepezil and Pharmaceutical Composition Thereof 审中-公开
标题翻译：多奈哌齐酸的酸加成盐及其药物组成
公开(公告)号：US20140243278A1
公开(公告)日：2014-08-28
申请号：US14131178
申请日：2012-07-03
申请人： Sunil Sadanand Nadkarni , Arunkumar Gupta , Jaya Abraham , Manish Parikh , Mahesh Suthar , Bipin Manavadariya , Vivek Mishra
发明人： Sunil Sadanand Nadkarni , Arunkumar Gupta , Jaya Abraham , Manish Parikh , Mahesh Suthar , Bipin Manavadariya , Vivek Mishra
IPC分类号： C07D211/32 , C07C65/01 , C07C57/15 , C07C59/70 , C07C65/11 , C07C309/19
CPC分类号： C07D211/32 , A61K9/0019 , A61K9/1647 , A61K31/445 , A61K47/10 , A61K47/14 , A61K47/26 , C07C57/15 , C07C59/70 , C07C65/01 , C07C65/11 , C07C309/19
摘要： Disclosed is an acid addition salt of donepezil, wherein acid counterion is selected from the group consisting of pamoic acid, cypionic acid, camphor sulfonic acid, enanthic acid, fusidic acid, gluceptic acid, gluconic acid, lactobionic acid, lauric acid, valeric acid, Dibenzoyl-D-Tartaric acid and terephthalic acid. Disclosed is a process for the preparation and pharmaceutical composition comprising the same. More specifically, disclosed is concerned with the pamoate acid addition salts of donepezil. Disclosed also is long acting formulation comprising the acid addition salt of donepezil and process for the preparation thereof.
摘要翻译：公开了多奈哌齐的酸加成盐，其中酸抗衡离子选自双羟萘酸，邻苯二甲酸，樟脑磺酸，庚酸，夫西地酸，葡庚糖酸，葡糖酸，乳糖酸，月桂酸，戊酸，二苯甲酰基-D-酒石酸和对苯二甲酸。公开了一种制备方法和包含其的药物组合物。更具体地，本发明涉及多奈哌齐的双羟萘酸加成盐。还公开了包含多奈哌齐的酸加成盐的长效制剂及其制备方法。

9. 发明申请

US20120101296A1 METHOD FOR PREPARING TRICYCLIC DERIVATIVES 有权
标题翻译：制备三环衍生物的方法
公开(公告)号：US20120101296A1
公开(公告)日：2012-04-26
申请号：US13381036
申请日：2010-06-29
申请人： Myung-Hwa Kim , In-Hae Ye , Jong-Hee Choi
发明人： Myung-Hwa Kim , In-Hae Ye , Jong-Hee Choi
IPC分类号： C07C231/14 , C07C69/76 , C07C49/84 , C07C51/087
CPC分类号： C07C319/20 , C07C51/06 , C07C65/01 , C07C67/08 , C07C67/30 , C07C233/65 , C07C235/42 , C07C2603/34 , C07D295/192 , C07C323/42 , C07C69/76
摘要： The present invention relates to a method for preparing a tricyclic derivative, and more particulary, to a method for preparing a tricyclic derivative inetermediate with high yield and purity, the method including: introducing a hydroxy group by esterifying and substituting 2-fluoroisophthalic acid compound; introducing a piperidyl group; introducing a hydroxy group through reduction reaction; and then hydrolyzing the resultant compound, and to a method for preparing the tricyclic derivative using said intermediate. According to the method of the present invention, it is possible to provide a tricyclic derivative and an intermediate thereof with high productivity and economic feasibility as well as high purity and yield, by purifying a compound using re-crystallization unlike typical methods of using column chromatography. In addition, the method of the present invention can be usefully used for industrial mass production because sodium borohydride or lithium aluminum hydride with low risk of a fire is used unlike typical methods of using lithium borohydride which is not industrially applicable due to high risk of a fire.
摘要翻译：本发明涉及一种制备三环衍生物的方法，更具体地说涉及一种以高产率和纯度制备三环衍生物三烯衍生物的方法，所述方法包括：通过酯化和取代2-氟间苯二甲酸化合物引入羟基; 引入哌啶基; 通过还原反应引入羟基; 然后水解所得化合物，以及使用所述中间体制备三环衍生物的方法。根据本发明的方法，通过使用重结晶纯化化合物，可以提供具有高生产率和经济可行性以及高纯度和收率的三环衍生物及其中间体，与使用柱色谱法的典型方法不同。此外，本发明的方法可以有用地用于工业大规模生产，因为使用低风险的硼氢化钠或氢化铝锂不同于使用不具有工业上适用的硼氢化锂的典型方法，这是因为高风险的火。

10. 发明授权

US07629489B2 Process for the synthesis of hydroxy aromatic acids 失效
公开(公告)号：US07629489B2
公开(公告)日：2009-12-08
申请号：US12056346
申请日：2008-03-27
申请人： Joachim C. Ritter
发明人： Joachim C. Ritter
IPC分类号： C07C65/01
CPC分类号： C07C63/00 , C07C51/02 , C07C51/367 , C07C51/412 , C07C65/01 , C07C65/03 , C07C65/05 , C07C65/10
摘要： Hydroxy aromatic acids are produced in high yields and high purity (>95%) from halogenated aromatic acids in a reaction mixture containing a copper source and a ligand that coordinates to copper.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式