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1. 发明申请

US20100048865A1 MICROWAVE-ASSISTED PEPTIDE SYNTHESIS 有权
标题翻译：微波辅助肽合成
公开(公告)号：US20100048865A1
公开(公告)日：2010-02-25
申请号：US12549445
申请日：2009-08-28
申请人： JONATHAN MCKINNON COLLINS , JOSEPH JOSHUA LAMBERT , MICHAEL JOHN COLLINS
发明人： JONATHAN MCKINNON COLLINS , JOSEPH JOSHUA LAMBERT , MICHAEL JOHN COLLINS
IPC分类号： C07K1/04 , C07K1/06
CPC分类号： B01J19/126 , B01J19/087 , B01J2219/0871 , B01J2219/0879 , B01J2219/1206 , B01J2219/1209 , B01J2219/1215 , B01J2219/1218 , B01J2219/1221 , B01J2219/1254 , B01J2219/126 , B01J2219/1272 , B01J2219/1293 , C07K1/045 , C07K1/063 , C07K5/08 , C07K7/06
摘要： An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.
摘要翻译：公开了用于促进肽的固相合成的仪器和方法。该方法包括以下步骤：通过将受保护的连接酸与去保护溶液混合在微波透明容器中，同时用微波照射混合的酸和溶液，活化第二个氨基酸，偶联同时用微波在同一容器中照射组合物的第二个氨基酸，并且通过将相连的肽与裂解组合物在同一容器中混合同时用微波照射组合物来将固定相树脂切断连接的肽。

2. 发明申请

US20080267841A1 REAL-TIME IMAGING AND SPECTROSCOPY DURING MICROWAVE ASSISTED CHEMISTRY 审中-公开
标题翻译：微波辅助化学实验中的实时成像和光谱
公开(公告)号：US20080267841A1
公开(公告)日：2008-10-30
申请号：US12146511
申请日：2008-06-26
申请人： Edward Earl King
发明人： Edward Earl King
IPC分类号： B01J19/12 , G01N1/44 , H05B6/80
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/00051 , B01J2219/00162 , B01J2219/1206 , B01J2219/1215 , B01J2219/126 , B01J2219/1269 , B01J2219/1275 , B01J2219/1278 , B01J2219/1281 , B01J2219/1284 , B01J2219/1293
摘要： An instrument and associated method are disclosed for conducting microwave assisted chemical reactions. The instrument includes a microwave cavity, preferably a closed microwave cavity, for conducting microwave assisted chemical reactions, and a source for applying microwave radiation within the cavity and to a vessel and its contents. The instrument also includes an illumination source for illuminating the vessel and its contents, as well as means for visually observing the vessel and its contents, an infrared detector for monitoring the temperature of the vessel and its contents, and means for preventing the illumination source from saturating the infrared detector, thereby enabling concurrent visual observation and infrared monitoring.
摘要翻译：公开了用于进行微波辅助化学反应的仪器和相关方法。仪器包括用于进行微波辅助化学反应的微波腔，优选封闭的微波腔，以及用于在空腔内以及容器及其内容物施加微波辐射的源。仪器还包括用于照明容器及其内容物的照明源，以及用于目视观察容器及其内容物的装置，用于监测容器及其内容物的温度的红外检测器，以及用于防止照明源使红外线检测器饱和，从而实现视觉观察和红外监测。

3. 发明申请

US20070102279A1 Method and Apparatus for Microwave Reduction of Organic Compounds 有权
标题翻译：用于微波还原有机化合物的方法和装置
公开(公告)号：US20070102279A1
公开(公告)日：2007-05-10
申请号：US11670041
申请日：2007-02-01
申请人： John Novak
发明人： John Novak
IPC分类号： C07F1/00 , B01J19/08
CPC分类号： H05B6/78 , A62D3/178 , A62D2101/20 , A62D2101/22 , B01J19/126 , B01J2219/00063 , B01J2219/0009 , B01J2219/00108 , B01J2219/00162 , B01J2219/1215 , B01J2219/1227 , B01J2219/123 , B01J2219/1233 , B01J2219/1239 , B01J2219/126 , B01J2219/1269 , B01J2219/1293 , B03B9/061 , B09B3/00 , B09B3/0083 , C08J3/28 , C08J11/10 , C10B7/06 , C10B19/00 , C10B53/00 , C10B53/06 , C10B53/07 , C10G1/00 , C10G1/10 , H05B6/806 , Y02E50/32 , Y02P20/143 , Y02W30/58 , Y02W30/702
摘要： The invention described herein generally pertains to utilization of high power density microwave energy to reduce organic compounds to carbon and their constituents, primarily in a gaseous state. The process includes, but is not limited to, scrap tires, plastics, asphalt roofing shingles, computer waste, medical waste, municipal solid waste, construction waste, shale oil, and PCB/PAH/HCB-laden materials. The process includes the steps of feeding organic material into a microwave applicator and exposing the material to microwave energy fed from at least two linear polarized sources in non-parallel alignment to each other, and collecting the material. The at least two sources of microwave energy are from a bifurcated waveguide assembly, whose outputs are perpendicular to each other and fed through waveguide of proper impedance, such that the microwave sources are physically and electrically 90° out of phase to each other. The microwave frequency is between 894 and 1000 MHz, preferably approximately 915 MHz.
摘要翻译：本文描述的本发明通常涉及利用高功率密度微波能量来将有机化合物还原成碳及其组分，主要是在气态下。该方法包括但不限于废旧轮胎，塑料，沥青屋面瓦，计算机废物，医疗废物，城市固体废物，建筑废料，页岩油和PCB / PAH / HCB负载材料。该方法包括以下步骤：将有机材料进料到微波施加器中，并将材料暴露于彼此以非平行排列方式从至少两个线性偏振光源馈送的微波能量，并收集材料。微波能量的至少两个来源于分支波导组件，其输出彼此垂直并通过适当阻抗的波导馈送，使得微波源彼此物理和电位相差90°。微波频率在894和1000MHz之间，优选大约915MHz。

4. 发明申请

US20060025569A1 Microwave-assisted peptide synthesis 有权
公开(公告)号：US20060025569A1
公开(公告)日：2006-02-02
申请号：US11235329
申请日：2005-09-26
申请人： Jonathan Collins , Joseph Lambert , Michael Collins
发明人： Jonathan Collins , Joseph Lambert , Michael Collins
IPC分类号： C07K1/02
CPC分类号： B01J19/126 , B01J19/087 , B01J2219/0871 , B01J2219/0879 , B01J2219/1206 , B01J2219/1209 , B01J2219/1215 , B01J2219/1218 , B01J2219/1221 , B01J2219/1254 , B01J2219/126 , B01J2219/1272 , B01J2219/1293 , C07K1/045 , C07K1/063 , C07K5/08 , C07K7/06
摘要： An instrument and process for accelerating the solid phase synthesis of peptides is disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, then activating a second amino acid by adding the second acid and an activating solution to the same vessel while irradiating the vessel with microwaves, then coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.

5. 发明申请

US20060025568A1 Microwave-assisted peptide synthesis 有权
公开(公告)号：US20060025568A1
公开(公告)日：2006-02-02
申请号：US11235328
申请日：2005-09-26
申请人： Jonathan Collins , Joseph Lambert , Michael Collins
发明人： Jonathan Collins , Joseph Lambert , Michael Collins
IPC分类号： C07K1/02 , B32B27/12
CPC分类号： B01J19/126 , B01J19/087 , B01J2219/0871 , B01J2219/0879 , B01J2219/1206 , B01J2219/1209 , B01J2219/1215 , B01J2219/1218 , B01J2219/1221 , B01J2219/1254 , B01J2219/126 , B01J2219/1272 , B01J2219/1293 , C07K1/045 , C07K1/063 , C07K5/08 , C07K7/06
摘要： An instrument and process for accelerating the solid phase synthesis of peptides is disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, then activating a second amino acid by adding the second acid and an activating solution to the same vessel while irradiating the vessel with microwaves, then coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.

6. 发明申请

US20020176814A1 Device for implementing chemical reactions and processes in high frequency fields 失效
标题翻译：用于实现高频场化学反应和工艺的装置
公开(公告)号：US20020176814A1
公开(公告)日：2002-11-28
申请号：US09980026
申请日：2002-03-29
发明人： Werner Lautenschlager , Bernd Ondruschka , Matthias Nuchter
IPC分类号： B01J019/08
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/1215 , B01J2219/1218 , B01J2219/1254 , B01J2219/126 , B01J2219/1293 , H05B6/6408
摘要： The aim of the invention is to create a device which operates in a highly reliable manner with minimum loss of energy, requiring a minimum amount of technical complexity for a wide range of applications used to carry out chemical reactions and processes in high frequency fields. According to the invention, rod-shaped elements are provided around the reactor (1) Said elements form a pressure-stable cage and can be individually fixed to the wall (4) of the high frequency chamber (2) with the aid of fixing elements (6). The rod-shaped elements respectively possess a guide (11) which is used to receive a crown-shaped holder (12) for the reactor (1) or a reactor closure (13, 13a) When the rod-like elements (5) are fixed in a positive fit, the holder (12) is secured in such a way that alignment and centering can occur. The inventive device advantageously enables energy to be supplied during decomposition, hydrolysis, chemical synthesis, extraction, distillation, drying and other reactions and processes.
摘要翻译：本发明的目的是创建一种以最低可靠性运行的装置，其能量损失最小，对于用于在高频场中进行化学反应和过程的广泛应用需要最小量的技术复杂性。根据本发明，围绕反应器（1）设置棒状元件。所述元件形成压力稳定的保持架，并可借助于固定元件单独地固定到高频室（2）的壁（4）（6）。棒状元件分别具有用于接收用于反应器（1）的冠状保持器（12）或反应器封闭件（13,13a）的引导件（11）。当棒状元件（5）为以正配合固定，保持器（12）以能够进行对准和定中心的方式固定。本发明的装置有利地能够在分解，水解，化学合成，萃取，蒸馏，干燥和其它反应和方法期间提供能量。

7. 发明授权

US10052607B2 Microwave-assisted peptide synthesis 有权
公开(公告)号：US10052607B2
公开(公告)日：2018-08-21
申请号：US15612389
申请日：2017-06-02
申请人： CEM CORPORATION
发明人： Jonathan McKinnon Collins , Joseph Joshua Lambert , Michael John Collins
IPC分类号： B01J19/12 , C07K1/06 , C07K7/06 , C07K5/08 , B01J19/08 , C07K1/04
CPC分类号： B01J19/126 , B01J19/087 , B01J2219/0871 , B01J2219/0879 , B01J2219/1206 , B01J2219/1209 , B01J2219/1215 , B01J2219/1218 , B01J2219/1221 , B01J2219/1254 , B01J2219/126 , B01J2219/1272 , B01J2219/1293 , C07K1/045 , C07K1/063 , C07K5/08 , C07K7/06
摘要： An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.

8. 发明申请

US20150090710A1 Microwave Heating System 审中-公开
标题翻译：微波加热系统
公开(公告)号：US20150090710A1
公开(公告)日：2015-04-02
申请号：US14498721
申请日：2014-09-26
申请人： Anton Paar GmbH
发明人： Heimo Kotzian , Rainer Zentner , Johannes Zach , Elisabeth Gangl
IPC分类号： H05B6/80 , H05B6/64
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/1218 , B01J2219/1227 , B01J2219/1233 , B01J2219/1257 , B01J2219/126 , B01J2219/1266 , B01J2219/1272 , H05B6/6402 , H05B6/6411 , H05B6/707
摘要： A microwave heating system comprises a bowl, dome and rotor device. The dome is fit to the bowl. The bowl and dome form a volume. The bowl is connected to a microwave source such that a microwave field is supplied to the volume. The microwave field is attenuated in a region between the rotor device and the dome compared to a region between the bowl and the rotor device. The rotor device is rotatably supported by the bowl and supports a reaction vessel. The rotor device includes a base plate with a through-hole and a tubular member that receives the reaction vessel. The base plate and tubular member are metal. The rotor device is coupled to the base plate so that a longitudinal axis of the tubular member passes through the through-hole.
摘要翻译：微波加热系统包括碗，圆顶和转子装置。圆顶适合碗。碗和圆顶形成一个体积。碗连接到微波源，使得微波场被供应到体积。与碗和转子装置之间的区域相比，微波场在转子装置和穹顶之间的区域中衰减。转子装置由碗可旋转地支撑并支撑反应容器。转子装置包括具有通孔的基板和容纳反应容器的管状部件。底板和管状构件是金属的。转子装置联接到基板，使得管状构件的纵向轴线穿过通孔。

9. 发明授权

US08846862B2 Microwave-assisted peptide synthesis 有权
标题翻译：微波辅助肽合成
公开(公告)号：US08846862B2
公开(公告)日：2014-09-30
申请号：US13866063
申请日：2013-04-19
申请人： CEM Corporation
发明人： Jonathan McKinnon Collins , Joseph Joshua Lambert , Michael John Collins
IPC分类号： A61K38/00 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , B01J19/08 , B01J19/12 , C07K1/04
CPC分类号： B01J19/126 , B01J19/087 , B01J2219/0871 , B01J2219/0879 , B01J2219/1206 , B01J2219/1209 , B01J2219/1215 , B01J2219/1218 , B01J2219/1221 , B01J2219/1254 , B01J2219/126 , B01J2219/1272 , B01J2219/1293 , C07K1/045 , C07K1/063 , C07K5/08 , C07K7/06
摘要： An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.
摘要翻译：公开了用于促进肽的固相合成的仪器和方法。该方法包括以下步骤：通过将受保护的连接酸与去保护溶液混合在微波透明容器中，同时用微波照射混合的酸和溶液，活化第二个氨基酸，偶联同时用微波在同一容器中照射组合物的第二个氨基酸，并且通过将相连的肽与裂解组合物在同一容器中混合同时用微波照射组合物来将固定相树脂切断连接的肽。

10. 发明授权

US08562793B2 Method and apparatus for microwave reduction of organic compounds 有权
标题翻译：微波还原有机化合物的方法和装置
公开(公告)号：US08562793B2
公开(公告)日：2013-10-22
申请号：US13616104
申请日：2012-09-14
申请人： John F. Novak
发明人： John F. Novak
IPC分类号： H05B6/80
CPC分类号： H05B6/78 , A62D3/178 , A62D2101/20 , A62D2101/22 , B01J19/126 , B01J2219/00063 , B01J2219/0009 , B01J2219/00108 , B01J2219/00162 , B01J2219/1215 , B01J2219/1227 , B01J2219/123 , B01J2219/1233 , B01J2219/1239 , B01J2219/126 , B01J2219/1269 , B01J2219/1293 , B03B9/061 , B09B3/00 , B09B3/0083 , C08J3/28 , C08J11/10 , C10B7/06 , C10B19/00 , C10B53/00 , C10B53/06 , C10B53/07 , C10G1/00 , C10G1/10 , H05B6/806 , Y02E50/32 , Y02P20/143 , Y02W30/58 , Y02W30/702
摘要： The invention pertains to utilization of high power density microwave energy to reduce organic compounds to carbon and their constituents, primarily in a gaseous state. The process includes, but is not limited to, scrap tires, plastics, asphalt roofing shingles, computer waste, medical waste, municipal solid waste, construction waste, shale oil, and PCB/PAH/HCB-laden materials. The process includes the steps of feeding organic material into a microwave applicator and exposing the material to microwave energy fed from at least two linear polarized sources in non-parallel alignment to each other, and collecting the material. The at least two sources of microwave energy are from a bifurcated waveguide assembly, whose outputs are perpendicular to each other and fed through waveguide of proper impedance, such that the microwave sources are physically and electrically 90° out of phase to each other. The microwave frequency is between 894 and 1000 MHz, preferably approximately 915 MHz.
摘要翻译：本发明涉及利用高功率密度微波能量来将有机化合物还原成主要在气态的碳及其组分。该方法包括但不限于废旧轮胎，塑料，沥青屋面瓦，计算机废物，医疗废物，城市固体废物，建筑废料，页岩油和PCB / PAH / HCB负载材料。该方法包括以下步骤：将有机材料进料到微波施加器中，并将材料暴露于彼此以非平行排列方式从至少两个线性偏振光源馈送的微波能量，并收集材料。微波能量的至少两个来源于分支波导组件，其输出彼此垂直并通过适当阻抗的波导馈送，使得微波源彼此物理和电位相差90°。微波频率在894和1000MHz之间，优选大约915MHz。

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