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1. 发明申请

US20050133498A1 Method and apparatus for continuous flow microwave-assisted chemistry techniques 审中-公开
标题翻译：连续流微波辅助化学技术的方法和装置
公开(公告)号：US20050133498A1
公开(公告)日：2005-06-23
申请号：US11047348
申请日：2005-01-28
申请人： Michael Collins , Michael Collins , Wyatt Hargett , Edward King , Gary Busse
发明人： Michael Collins , Michael Collins , Wyatt Hargett , Edward King , Gary Busse
IPC分类号： B01J19/12 , C07C51/38 , C07C67/03 , C07C67/08 , C07C221/00 , C07C223/06 , H05B6/78 , H05B6/80
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/0009 , B01J2219/00162 , B01J2219/1227 , B01J2219/1239 , C07C51/38 , C07C67/03 , C07C67/08 , C07C221/00 , C07C57/44 , C07C69/76 , C07C69/78 , C07C223/06
摘要： The invention is a method and associated instrument for microwave assisted chemistry. The invention includes the steps of directing a continuous flow of fluid through a microwave cavity while applying microwave radiation to the cavity and to the continuous flow of materials therein, monitoring the pressure of the fluid in the cavity; and cooling the fluid in the cavity when the pressure exceeds a predetermined setpoint pressure.
摘要翻译：本发明是用于微波辅助化学的方法和相关仪器。本发明包括以下步骤：引导流体连续流过微波空腔，同时向空腔施加微波辐射并且在其中连续流动材料，监测空腔中的流体的压力; 并且当压力超过预定的设定点压力时，冷却腔体中的流体。

2. 发明申请

US20060219710A1 Spectroscopy-based real-time control for microwave-assisted chemistry 有权
公开(公告)号：US20060219710A1
公开(公告)日：2006-10-05
申请号：US11097859
申请日：2005-04-01
申请人： Michael McManus , Michael Collins , Michael Collins
发明人： Michael McManus , Michael Collins , Michael Collins
IPC分类号： H05B6/50
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/1215 , B01J2219/1227 , B01J2219/123 , B01J2219/1233 , B01J2219/1236 , B01J2219/1239 , B01J2219/1242 , B01J2219/1245 , B01J2219/1254 , B01J2219/1263 , B01J2219/1266 , B01J2219/1269 , B01J2219/1272 , B01J2219/1284 , B01J2219/1293 , G01N21/65 , G01N21/68
摘要： The invention is an instrument and method for microwave-assisted chemical synthesis. The instrument includes a source of microwave radiation for applying microwave energy to a sample, a microwave cavity in wave communication with the source for holding the sample during the application of microwave energy, and a substantially monochromatic radiation source in electromagnetic communication with the cavity for applying substantially monochromatic light to the sample. The instrument further includes a detector positioned to detect Raman scattering of light from the monochromatic source by the sample, and a controller in signal communication with the microwave energy source and the Raman scattering detector for moderating the application of microwave energy to the sample based upon the detected Raman scattering.

3. 发明申请

US20060038118A1 Microwave-assisted chromatography preparation 有权
标题翻译：微波辅助色谱法制备
公开(公告)号：US20060038118A1
公开(公告)日：2006-02-23
申请号：US10923243
申请日：2004-08-20
申请人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
发明人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
IPC分类号： H05H3/02
CPC分类号： H05B6/806 , F26B3/347 , F26B5/048 , F26B9/003 , F26B21/14 , G01N1/44 , G01N30/06 , G01N2030/567
摘要： An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
摘要翻译：公开了用于制备用于柱色谱法的样品的仪器和相关方法。该方法包括以下步骤：向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物，然后将吸收介质与样品混合以吸收溶剂，该介质与液相色谱相容，将期望的产品分离，对预期产品具有化学惰性，并且以足以提供介质和样品的基本上干燥的混合物的量加入，但小于在液相色谱法过度扩大样品分辨率的量，然后将微波能量施加到介质和样品的干燥混合物中，从而促使溶剂在微波能量的影响下蒸发，然后将介质和剩余样品的干混合物加入液相色谱柱中，剩余样品的组分用于鉴定和纯化目的。

4. 发明授权

US07939785B2 Microwave-assisted chromatography preparation 有权
标题翻译：微波辅助色谱法制备
公开(公告)号：US07939785B2
公开(公告)日：2011-05-10
申请号：US12020711
申请日：2008-01-28
申请人： Michael Collins, Sr. , Wyatt P. Hargett, Jr. , James Edward Thomas , E. Keller Barnhardt , Michael Collins, Jr.
发明人： Michael Collins, Sr. , Wyatt P. Hargett, Jr. , James Edward Thomas , E. Keller Barnhardt , Michael Collins, Jr.
IPC分类号： H05B6/64
CPC分类号： H05B6/806 , F26B3/347 , F26B5/048 , F26B9/003 , F26B21/14 , G01N1/44 , G01N30/06 , G01N2030/567
摘要： An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
摘要翻译：公开了用于制备用于柱色谱法的样品的仪器和相关方法。该方法包括以下步骤：向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物，然后将吸收介质与样品混合以吸收溶剂，该介质与液相色谱相容，将期望的产品分离，对预期产品具有化学惰性，并且以足以提供介质和样品的基本上干燥的混合物的量加入，但小于在液相色谱法过度扩大样品分辨率的量，然后将微波能量施加到介质和样品的干燥混合物中，从而促使溶剂在微波能量的影响下蒸发，然后将介质和剩余样品的干混合物加入液相色谱柱中，剩余样品的组分用于鉴定和纯化目的。

5. 发明申请

US20080116363A1 MICROWAVE-ASSISTED CHROMATOGRAPHY PREPARATION 有权
标题翻译：微波辅助色谱准备
公开(公告)号：US20080116363A1
公开(公告)日：2008-05-22
申请号：US12020711
申请日：2008-01-28
申请人： MICHAEL COLLINS , WYATT HARGETT , JAMES THOMAS , MICHAEL COLLINS , E. BARNHARDT
发明人： MICHAEL COLLINS , WYATT HARGETT , JAMES THOMAS , MICHAEL COLLINS , E. BARNHARDT
IPC分类号： H05H3/02
CPC分类号： H05B6/806 , F26B3/347 , F26B5/048 , F26B9/003 , F26B21/14 , G01N1/44 , G01N30/06 , G01N2030/567
摘要： An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
摘要翻译：公开了用于制备用于柱色谱法的样品的仪器和相关方法。该方法包括以下步骤：向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物，然后将吸收介质与样品混合以吸收溶剂，该介质与液相色谱相容，将期望的产品分离，对预期产品具有化学惰性，并且以足以提供介质和样品的基本上干燥的混合物的量加入，但小于在液相色谱法过度扩大样品分辨率的量，然后将微波能量施加到介质和样品的干燥混合物中，从而促使溶剂在微波能量的影响下蒸发，然后将介质和剩余样品的干混合物加入液相色谱柱中，剩余样品的组分用于鉴定和纯化目的。

6. 发明申请

US20060261058A1 Microwave-Assisted Chromatography Preparation 有权
标题翻译：微波辅助色谱法制备
公开(公告)号：US20060261058A1
公开(公告)日：2006-11-23
申请号：US11456997
申请日：2006-07-12
申请人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
发明人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
IPC分类号： B01L9/00
CPC分类号： H05B6/806 , F26B3/347 , F26B5/048 , F26B9/003 , F26B21/14 , G01N1/44 , G01N30/06 , G01N2030/567
摘要： An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
摘要翻译：公开了用于制备用于柱色谱法的样品的仪器和相关方法。该方法包括以下步骤：向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物，然后将吸收介质与样品混合以吸收溶剂，该介质与液相色谱相容，将期望的产品分离，对预期产品具有化学惰性，并且以足以提供介质和样品的基本上干燥的混合物的量加入，但小于在液相色谱法过度扩大样品分辨率的量，然后将微波能量施加到介质和样品的干燥混合物中，从而促使溶剂在微波能量的影响下蒸发，然后将介质和剩余样品的干混合物加入液相色谱柱中，剩余样品的组分用于鉴定和纯化目的。

7. 发明申请

US20190385196A1 INCENTIVIZED AUCTION STYLE MESSAGING 审中-公开
公开(公告)号：US20190385196A1
公开(公告)日：2019-12-19
申请号：US16392442
申请日：2019-04-23
申请人： Michael Collins Byrne
发明人： Michael Collins Byrne
IPC分类号： G06Q30/02
摘要： A system for incentivization of communications, comprising an incentivization engine and an auction service, and a method for using such a system for providing incentivization of user communications and user competition for incentives.

8. 发明授权

US10258554B2 Fluoride free and anionic surfactant free dentifrice having a high micro efficacy 有权
公开(公告)号：US10258554B2
公开(公告)日：2019-04-16
申请号：US13574100
申请日：2011-01-28
申请人： Michael Collins , Linh Fruge , Barbara Hepler , Kimdra Smith-Webster
发明人： Michael Collins , Linh Fruge , Barbara Hepler , Kimdra Smith-Webster
IPC分类号： A61Q11/00 , A61K8/00 , A61K8/34 , A61K8/36
摘要： An oral care composition and method are described in which the composition is free of an anionic surfactant and a fluoride source.

9. 发明授权

US10011990B2 Laminated air circulation board 有权
公开(公告)号：US10011990B2
公开(公告)日：2018-07-03
申请号：US15359655
申请日：2016-11-23
申请人： P. Michael Collins
发明人： P. Michael Collins
IPC分类号： E04B1/70 , E04B2/44 , E04C2/04 , E04C2/32 , E04C2/34 , E04C2/06
CPC分类号： E04C2/3405 , E04B1/7076 , E04B2/44 , E04C2/06 , E04C2/32 , E04C2002/3427 , E04C2002/3472 , E04F13/045 , E04F13/047
摘要： A laminated board is secured to the inner wall of a cavity wall construction to establish a defined spacing between the inner and outer walls and prevent excess mortar from bridging to the inner wall. The laminated board has a series of spaced sockets into which fasteners may project into the face of the inner wall or framing thereof to secure the outer wall. The board is installed prior to the construction of the outer wall and establishes a minimum spacing or gap between the walls based upon the thickness of the board. The outer wall is constructed immediately adjacent to the outer face of the laminated board. The board is impervious and eliminates bridging by the mortar, eliminates transfer of bulk water from the exterior finish to the inner wall and provides an air conduit to exhaust even the minimal amounts of vapor that will occur in the cavity.

10. 发明授权

US09707058B2 Patient-specific implants with improved osseointegration 有权
公开(公告)号：US09707058B2
公开(公告)日：2017-07-18
申请号：US12501163
申请日：2009-07-10
申请人： Jeffrey A. Bassett , Michael Collins , Sean Cahill
发明人： Jeffrey A. Bassett , Michael Collins , Sean Cahill
IPC分类号： A61C8/00 , A61F2/28 , A61L27/08 , A61L27/30 , A61L27/56 , B33Y80/00 , A61F2/30
CPC分类号： A61C8/0012 , A61C8/0013 , A61F2/2803 , A61F2/30942 , A61F2002/30011 , A61F2002/3092 , A61F2002/30929 , A61F2002/30952 , A61F2002/30962 , A61F2002/30981 , A61F2250/0023 , A61F2310/00161 , A61F2310/00544 , A61L27/08 , A61L27/30 , A61L27/56 , A61L2430/02 , B33Y80/00 , Y10T29/49568
摘要： A patient-specific bone implant has a porous body with a core material covered with tantalum. It is made with unique outer dimensions selected to match a specific patient.

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