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1. 发明公开

US20240261484A1 METHOD OF REMOVING BLOOD FROM AN EXTRACORPOREAL BLOOD CIRCUIT, TREATMENT APPARATUS, AND TUBE SYSTEM 审中-公开
公开(公告)号：US20240261484A1
公开(公告)日：2024-08-08
申请号：US18602722
申请日：2024-03-12
申请人： Fresenius Medical Care Deutschland GmbH
发明人： Goetz Guenther , Joachim Manke
IPC分类号： A61M1/36 , A61M1/34
CPC分类号： A61M1/3646 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/362265 , A61M1/362266 , A61M1/3626 , A61M1/3643 , A61M1/3644 , A61M1/3653 , A61M1/3655 , A61M2205/12 , A61M2205/60
摘要： The present invention relates to a method of removing blood from an extracorporeal blood circuit following termination of a blood treatment session, wherein blood is concurrently removed both from an arterial conduit portion and from a venous conduit portion of the extracorporeal blood circuit. It further relates to a method for recognizing and/or eliminating air inclusions in or from an extracorporeal blood circuit and a treatment apparatus as well as a tube system.

2. 发明授权

US11850341B2 Flow balancing devices, methods, and systems 有权
公开(公告)号：US11850341B2
公开(公告)日：2023-12-26
申请号：US17879455
申请日：2022-08-02
申请人： NxStage Medical, Inc.
发明人： Jeffrey H. Burbank , Dennis M. Treu , Daniel Joseph Rubery, Jr. , Scott W. Newell , James M. Brugger , William J. Schnell , William K. Weigel , Steven A. White , Mark T. Wyeth , Jerome James , David Desouza , Joseph E. Turk, Jr. , Garrett Casey
IPC分类号： A61M1/14 , A61M1/34 , A61M1/16 , A61M1/36
CPC分类号： A61M1/1605 , A61M1/14 , A61M1/165 , A61M1/1613 , A61M1/1615 , A61M1/1647 , A61M1/341 , A61M1/3403 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3444 , A61M1/3448 , A61M1/3609 , A61M1/3635 , A61M1/34 , A61M1/3607 , A61M2205/05 , A61M2205/058 , A61M2205/3331 , A61M2205/3334 , A61M2205/3341 , A61M2205/3351 , A61M2205/3355 , A61M2205/3365 , A61M2205/3368 , A61M2205/502 , A61M2205/702
摘要： The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

3. 发明申请

US20190231956A1 Flow Balancing Devices, Methods, and Systems 审中-公开
公开(公告)号：US20190231956A1
公开(公告)日：2019-08-01
申请号：US16381354
申请日：2019-04-11
申请人： NxStage Medical, Inc.
发明人： Jeffrey H. BURBANK , Dennis M. TREU , Daniel J. RUBERY, JR. , Scott W. NEWELL , James M. BRUGGER , William J. SCHNELL , William K. WEIGEL , Steven A. WHITE , Mark T. WYETH , Jerome JAMES , David DESOUZA , Joseph E. TURK, JR. , Garrett CASEY
IPC分类号： A61M1/16 , A61M1/34 , A61M1/14 , A61M1/36
CPC分类号： A61M1/1605 , A61M1/14 , A61M1/1613 , A61M1/1615 , A61M1/1647 , A61M1/165 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3444 , A61M1/3448 , A61M1/3607 , A61M1/3609 , A61M1/3635 , A61M2205/058 , A61M2205/15 , A61M2205/3331 , A61M2205/3334 , A61M2205/3341 , A61M2205/3351 , A61M2205/3355 , A61M2205/3365 , A61M2205/3368 , A61M2205/502 , A61M2205/702
摘要： The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

4. 发明授权

US10052423B2 Apparatus for extracorporeal treatment of blood and process of calculating set flow rates in a medical apparatus for delivery or collection of fluids 有权
公开(公告)号：US10052423B2
公开(公告)日：2018-08-21
申请号：US14342025
申请日：2012-08-23
申请人： Dominique Pouchoulin
发明人： Dominique Pouchoulin
IPC分类号： A61M1/16 , G01F1/00 , G06F19/00 , A61M1/34 , A61M1/36
CPC分类号： A61M1/1613 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/341 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3607 , A61M1/3609 , A61M2202/0413 , A61M2205/3331 , A61M2205/3334 , A61M2205/3393 , A61M2205/502 , A61M2205/52 , A61M2205/75 , G01F1/00 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit (10) is configured calculate set values of two or more of the fluid flow rates based on a fluid flow rate set by the operator and on a prescribed dose value (Dset).

5. 发明授权

US09925321B2 Apparatus for extracorporeal blood treatment 有权
公开(公告)号：US09925321B2
公开(公告)日：2018-03-27
申请号：US14654066
申请日：2013-12-16
申请人： GAMBRO LUNDIA AB
发明人： Alessandro Surace , Paolo Rovatti
IPC分类号： A61M1/16 , A61M1/34 , A61M1/36
CPC分类号： A61M1/1613 , A61M1/16 , A61M1/1603 , A61M1/1605 , A61M1/1611 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3462 , A61M1/3465 , A61M1/36 , A61M1/3607 , A61M2205/3303 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3379 , A61M2205/3393 , A61M2205/502 , A61M2230/20 , A61M2230/65
摘要： It is disclosed an apparatus for extracorporeal blood treatment (1) having a control unit (15) connected to an ultrafiltration device (20) and to a fluid preparation section (30) of fresh dialysis liquid. The control unit (15) is configured to receive measured values of the change of blood volume, the amount of ultrafiltration volume, and conductivity or to the concentration for at least one substance in the blood (BV %mes(t); UFmes(t), WLmes(t); Cbmes(t)); the control unit (15) is also configured to receive prescription values for the same parameters and to control ultrafiltration and adjust conductivity in the fresh dialysis liquid based on the difference between said measured values and said prescription values.

6. 发明申请

US20170065760A1 APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT 审中-公开
标题翻译：用于提取血液治疗的装置
公开(公告)号：US20170065760A1
公开(公告)日：2017-03-09
申请号：US15353883
申请日：2016-11-17
申请人： GAMBRO LUNDIA AB
发明人： Mauro Suffritti , Michela Carpani
IPC分类号： A61M1/34 , B01D61/32 , B01D61/22
CPC分类号： A61M1/341 , A61M1/1603 , A61M1/1615 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3639 , A61M2205/3331 , A61M2205/502 , A61M2205/52 , B01D61/22 , B01D61/32 , B01D2311/14
摘要： An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9; 9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber. A regulating device (20) of a transmembrane pressure is active on at least one of the lines and a control unit (15) is configured to: command the regulating device (20) by setting a first increase (δTMP1), determine a value of a control parameter (φ1) corresponding to the first increase, compare the value of the control parameter (φ1) with a reference value (φref) and, if the value of the control parameter is greater than the reference value, command the regulating device (20) by setting a second increase (δTMP2) which is greater than the first increase (δTMP1).
摘要翻译：一种用于体外血液处理的装置，包括具有通过半透膜（5）彼此分离的第一室（3）和第二室（4）的处理单元（2），连接在入口与第一腔室（3）和血液回流管线（7）连接在出口与第一腔室; 更换流体的输液管线（9; 9a，9b）和连接在第二室的出口处的排液管线（10）。跨膜压力的调节装置（20）在至少一条线路上有效，并且控制单元（15）被配置为：通过设定第一增加（δTMP1）来指示调节装置（20），确定对应于第一增加的控制参数（φ1），将控制参数（φ1）的值与参考值（φref）进行比较，并且如果控制参数的值大于参考值，则命令调节装置 20）通过设定大于第一增加（δTMP1）的第二增加（δTMP2）。

7. 发明申请

US20160310656A1 EXTRACORPOREAL BLOOD TREATMENT SYSTEM, DISPOSABLE SET AND VALVE UNIT FOR PRE/POST INFUSION 审中-公开
标题翻译：超声波血液治疗系统，预先/后期输注的置换套和阀组
公开(公告)号：US20160310656A1
公开(公告)日：2016-10-27
申请号：US15102998
申请日：2014-10-09
申请人： GAMBRO LUNDIA AB
发明人： Luca Vinci
IPC分类号： A61M1/34 , A61M1/36 , A61M39/24
CPC分类号： A61M1/3434 , A61M1/342 , A61M1/3627 , A61M39/24 , A61M2039/2453 , A61M2039/2466 , A61M2205/11 , A61M2205/121 , A61M2205/128 , A61M2205/50 , A61M2205/52
摘要： An extracorporeal blood treatment system has a first holder (18), a second holder (19), an infusion pump (4) and an infusion valve unit (13). The first holder (18) is mounted on a housing (1a) of the system and configured to hold a blood treatment device (2). The second holder (19) is mounted on the housing (1a) and configured to hold an extracorporeal blood circuit (3) coupled to the blood treatment device (2). The infusion valve unit (13) has a first part (13b) and a second part (13a) releasable connectable to the first part (13b). The first part (13b) is mounted on the housing (1a), and has an inlet (25) coupled to the infusion pump (4). The second part (13a) has a first outlet (7a) and a second outlet (10a) that are connected to an infusion circuit configured to couple to the extracorporeal blood circuit (3). Further, the second part (13a) has a one-way valve configured to allow infusion liquid to flow from the inlet (25) towards at least one of the first and second outlets (7a, 10a), and to block fluid flow towards the inlet (25). The extracorporeal blood circuit (3) with the withdrawal and return lines (6, 5) and an air trap (8), the infusion circuit comprising the pre and post infusion lines (10, 7) and the second part (13a) of the infusion valve unit (13) form part of a disposable set which is replaced after use.
摘要翻译：体外血液处理系统具有第一保持器（18），第二保持器（19），输液泵（4）和输液阀单元（13）。第一保持器（18）安装在系统的壳体（1a）上并构造成保持血液处理装置（2）。第二保持器（19）安装在壳体（1a）上并构造成保持与血液处理装置（2）连接的体外血液回路（3）。输液阀单元（13）具有可拆卸地连接到第一部分（13b）的第一部分（13b）和第二部分（13a）。第一部分（13b）安装在壳体（1a）上，并且具有联接到输注泵（4）的入口（25）。第二部分（13a）具有连接到配置成耦合到体外血液回路（3）的输注电路的第一出口（7a）和第二出口（10a）。此外，第二部分（13a）具有单向阀，其构造成允许输液从入口（25）朝向第一和第二出口（7a，10a）中的至少一个流动，并阻止流体流向入口（25）。具有撤出和返回管线（6,5）和空气阱（8）的体外血液回路（3），输注回路包括输液管线（10,7）和第二部分（13a）输液阀单元（13）形成使用后更换的一次性套件的一部分。

8. 发明授权

US09393358B2 Method as well as apparatuses for testing at least one function of a medical functional device 有权
公开(公告)号：US09393358B2
公开(公告)日：2016-07-19
申请号：US13559873
申请日：2012-07-27
申请人： Soeren Gronau , Joachim Manke , Ralf Mueller , Ingo Schaefer
发明人： Soeren Gronau , Joachim Manke , Ralf Mueller , Ingo Schaefer
IPC分类号： A61M1/34
CPC分类号： A61M1/1621 , A61M1/14 , A61M1/1605 , A61M1/34 , A61M1/3413 , A61M1/3434 , A61M1/3607 , A61M39/24 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/27 , A61M2205/3306 , A61M2205/3331 , A61M2205/3368 , A61M2205/50 , A61M2205/70
摘要： The invention relates to a method for testing at least one function of a medical functional device which is inserted in and connected and compressed with a medical treatment apparatus, and/or a function of this treatment apparatus, wherein between a hydraulic device or a pneumatic unit of the treatment apparatus and the functional device at least one fluid communication is established. It further relates to a detection device which is programmed and/or configured for executing the method according to the invention as well as a medical treatment apparatus which comprises at least one detection device and/or is in signal transmission or is connected for signal transmission with it, a digital storage medium, a computer program product as well as a computer program.

9. 发明申请

US20160106901A1 RENAL FAILURE THERAPY MACHINES AND METHODS INCLUDING CONVECTIVE AND DIFFUSIVE CLEARANCE 有权
标题翻译：肾衰竭治疗机制及方法，包括有针对性和差异性的清除
公开(公告)号：US20160106901A1
公开(公告)日：2016-04-21
申请号：US14976773
申请日：2015-12-21
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Musalem El Sayyid , Shahid Din
IPC分类号： A61M1/16 , A61M1/34
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A renal failure therapy machine includes a blood cleaning filter, a sorbent device configured to regenerate used therapy fluid from the blood cleaning filter, a therapy fluid pump configured to pump regenerated therapy fluid from the sorbent device back to the blood cleaning filter, and a flow restrictor in fluid communication with the blood cleaning filter, the therapy fluid pump and the sorbent device, the flow restrictor configured to cause regenerated therapy fluid pumped by the therapy fluid pump from the sorbent device to the blood cleaning filter to be pressurized so that a first amount of the regenerated therapy fluid performs convective clearance and a second amount of the regenerated therapy fluid performs diffusive clearance.
摘要翻译：肾衰竭治疗机包括血液清洁过滤器，被配置为从血液清洁过滤器再生使用的治疗流体的吸附剂装置，被配置为将再生的治疗流体从吸附装置泵回到血液净化过滤器的治疗液泵，与血液净化过滤器，治疗流体泵和吸附剂装置流体连通的限流器，流量限制器构造成使由治疗流体泵从吸附装置泵送到血液净化过滤器的再生治疗液被加压，使得第一再生治疗液的量进行对流清除，第二量的再生治疗液进行扩散间隙。

10. 发明授权

US09302039B2 Hemodialysis system including a disposable cassette 有权
标题翻译：血液透析系统包括一次性盒式磁带
公开(公告)号：US09302039B2
公开(公告)日：2016-04-05
申请号：US14549818
申请日：2014-11-21
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Mutasem El Sayyid , Shahid Din
IPC分类号： A61M37/00 , A61M1/16 , A61M1/34 , A61M1/36 , A61M1/28
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A dialysis system includes a dialyzer, a sorbent cartridge configured to clean used dialysate from the dialyzer, a dialysate pump actuator configured to pump dialysate to the dialyzer, and a conductivity sensor located adjacent to a temperature sensor. The dialysis system also includes a disposable cassette configured to carry dialysate pumped by the dialysate pump actuator. The disposable cassette includes a combined conductivity and temperature sensor fluid chamber separate from the conductivity sensor and the temperature sensor and located so as to operate with the conductivity sensor and the temperature sensor, respectively, when mounted for operation.
摘要翻译：透析系统包括透析器，配置成从透析器清洁用过的透析液的吸附剂盒，配置成将透析液泵送到透析器的透析泵致动器，以及位于温度传感器附近的电导率传感器。透析系统还包括被配置为承载由透析泵致动器泵送的透析液的一次性盒。一次性盒包括与电导率传感器和温度传感器分离的组合的电导率和温度传感器流体室，并分别安装在操作时，与电导率传感器和温度传感器一起工作。

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