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1. 发明申请

US20210069342A1 ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN ROR1 AND USE FOR THE SAME 有权
公开(公告)号：US20210069342A1
公开(公告)日：2021-03-11
申请号：US16940326
申请日：2020-07-27
申请人： Yun Hee Park , Ho Young Song , Hyun Min Ryu , Sung Min Kim , Ju Yuel Baek , Ji Hye Oh , Nara Han , Hyoung Rae Kim , Kyung Eun Park , Hyeun Joung Lee , Ju Young Lee , Dae Hyuck Kang , Young-Jae Yang , Ji-Na You , Yong Zu Kim , Chang Sun Lee , Jeiwook Chae , Jinwon Jung , Juhee Kim , Bora Lee , Daehae Song , Byungje Sung , Donghoon Yeom , Jaehyun Eom , Youngeun Hong , Jinhyung Ahn , Yangsoon Lee , Kyungjin Park , Jiseon Yoo , Minji Park
发明人： Yun Hee Park , Ho Young Song , Hyun Min Ryu , Sung Min Kim , Ju Yuel Baek , Ji Hye Oh , Nara Han , Hyoung Rae Kim , Kyung Eun Park , Hyeun Joung Lee , Ju Young Lee , Dae Hyuck Kang , Young-Jae Yang , Ji-Na You , Yong Zu Kim , Chang Sun Lee , Jeiwook Chae , Jinwon Jung , Juhee Kim , Bora Lee , Daehae Song , Byungje Sung , Donghoon Yeom , Jaehyun Eom , Youngeun Hong , Jinhyung Ahn , Yangsoon Lee , Kyungjin Park , Jiseon Yoo , Minji Park
IPC分类号： A61K47/68 , C07K16/28 , A61P35/00
摘要： The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically diseases associated with over-expression of ROR1, for example cancer. More specifically, the present invention relates to an antibody-drug conjugate comprising an antibody that binds to ROR1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.

2. 发明申请

US20140196776A1 SOLAR CELL APPARATUS AND METHOD OF FABRICATING THE SAME 有权
标题翻译：太阳能电池装置及其制造方法
公开(公告)号：US20140196776A1
公开(公告)日：2014-07-17
申请号：US14123462
申请日：2012-05-30
申请人： Kyung Eun Park
发明人： Kyung Eun Park
IPC分类号： H01L31/061 , H01L31/18
CPC分类号： H01L31/035281 , H01L31/0322 , H01L31/0468 , H01L31/061 , H01L31/068 , H01L31/0749 , H01L31/075 , H01L31/1804 , H01L31/1884 , Y02E10/541 , Y02E10/547 , Y02E10/548 , Y02P70/521
摘要： Disclosed are a solar cell apparatus and a method of fabricating the same. The solar cell apparatus includes a substrate, a first electrode layer on the substrate, a plurality of light absorbing columns on the first electrode layer, and a second electrode layer on the light absorbing columns.
摘要翻译：公开了一种太阳能电池装置及其制造方法。太阳能电池装置包括基板，基板上的第一电极层，第一电极层上的多个吸光塔和吸光塔上的第二电极层。

3. 发明授权

US09573907B2 2, 4-pyrimidine derivatives and use thereof 有权
标题翻译： 2,4-嘧啶衍生物及其用途
公开(公告)号：US09573907B2
公开(公告)日：2017-02-21
申请号：US13505651
申请日：2010-11-02
申请人： Sunghoon Kim , Jung Min Han , Hyeong Rae Kim , Dong Ju Jeon , Jong Hwan Song , Kyung Eun Park
发明人： Sunghoon Kim , Jung Min Han , Hyeong Rae Kim , Dong Ju Jeon , Jong Hwan Song , Kyung Eun Park
IPC分类号： A61K31/506 , A61K31/5377 , C07D409/12 , C07D239/60 , C07D413/12 , C07D239/52 , C07D401/12
CPC分类号： C07D239/60 , C07D239/52 , C07D401/12
摘要： The present invention relates to novel 2,4-pyrimidine derivatives and a use thereof, and more particularly, to pyrimidine derivatives which are effective for systemic lupus erythematosus, a composition for preventing and treating systemic lupus erythematosus comprising the same as an active ingredient and a method for screening the same. The present inventors found novel materials inhibiting surface translocation of gp96 by mimicking a function of AIMP1 which is a molecular anchor for an intracellular residence of gp96, and identified in vitro and in vivo activity of the materials for preventing and treating SLE by alleviating SLE plasma in autoimmune diseases. Therefore, the present invention provides a novel method for screening a therapeutic agent for SLE, and preventing or treating SLE using the mechanism.
摘要翻译：本发明涉及新的2,4-嘧啶衍生物及其用途，更具体地涉及对系统性红斑狼疮有效的嘧啶衍生物，用于预防和治疗包含其作为活性成分的系统性红斑狼疮的组合物和筛选方法本发明人通过模拟作为gp96细胞内宿主的分子锚的AIMP1的功能，发现抑制gp96的表面易位的新型材料，并通过减轻SLE等离子体来预防和治疗SLE的材料的体外和体内活性自身免疫性疾病因此，本发明提供了用于筛选SLE治疗剂以及使用该机制预防或治疗SLE的新方法。

4. 发明授权

US5988853A Method for placing names for point-features on a map based on a plane sweeping technique 失效
标题翻译：基于平面扫描技术在地图上放置点特征的名称的方法
公开(公告)号：US5988853A
公开(公告)日：1999-11-23
申请号：US943596
申请日：1997-10-03
申请人： Jang Su Kim , Kyeong Hee Oh , Kyung Eun Park , Jong Won Lee
发明人： Jang Su Kim , Kyeong Hee Oh , Kyung Eun Park , Jong Won Lee
IPC分类号： G06F17/24 , G06F17/00
CPC分类号： G06F17/243
摘要： In an automatic mapping system, a plurality of names are placed on a map in association with a plurality of corresponding point-features with minimized overlapping among the names. First a minimum bounding rectangle (MBR) is placed on a predetermined position of a target point located on a predetermined direction-uppermost position from point-features, where the MBR is selected for representing a name corresponding to the target point. Next, it is determined whether the MBR is overlapped with at least one of previously assigned MBRs and if the MBR is not overlapped with any of the previously assigned MBRs, the current position of the MBR is determined and the name is placed on the MBR. If the MBR is overlapped with at least one of the previously assigned MBRs, it is determined whether it is possible to continuously shift the MBR around the target point so that the MBR located on one of shifted positions is not overlapped with any of the previously assigned MBRs and, if possible, the MBR is located on the shifted position and the name is placed on the MBR. Another point-feature is assigned and located on a predetermined direction-uppermost position from the remaining point-features as a target point and the above steps are repeated until all of the point features contained on the map are processed.
摘要翻译：在自动映射系统中，将多个名称与多个对应的点特征相关联地放置在地图上，并且在名称之间具有最小化的重叠。首先，将最小边界矩形（MBR）放置在位于从特征点的预定方向 - 最上方位置的目标点的预定位置，其中选择MBR以表示与目标点相对应的名称。接下来，确定MBR是否与先前分配的MBR中的至少一个重叠，并且如果MBR与先前分配的任何MBR不重叠，则确定MBR的当前位置并将名称放置在MBR上。如果MBR与先前分配的MBR中的至少一个重叠，则确定是否可以围绕目标点连续地移动MBR，使得位于移位位置之一上的MBR不与先前分配的任何一个重叠 MBR，如果可能，MBR位于移位的位置，名称放在MBR上。分配另一个点特征并将其定位在作为目标点的剩余点特征的预定方向 - 最上位置上，并且重复上述步骤，直到处理包含在地图上的所有点特征。

5. 发明申请

US20120322802A1 NOVEL 2, 4-PYRIMIDINE DERIVATIVES AND USE THEREOF 有权
标题翻译：新二氢吡啶衍生物及其用途
公开(公告)号：US20120322802A1
公开(公告)日：2012-12-20
申请号：US13505651
申请日：2010-11-02
申请人： Sunghoon Kim , Jung Min Han , Hyeong Rae Kim , Dong Ju Jeon , Jong Hwan Song , Kyung Eun Park
发明人： Sunghoon Kim , Jung Min Han , Hyeong Rae Kim , Dong Ju Jeon , Jong Hwan Song , Kyung Eun Park
IPC分类号： A61K31/505 , C07D401/12 , A61K31/506 , C40B30/04 , A61K31/5377 , A61P29/00 , C07D409/12 , C07D239/60 , C07D413/12
CPC分类号： C07D239/60 , C07D239/52 , C07D401/12
摘要： The present invention relates to novel 2,4-pyrimidine derivatives and a use thereof, and more particularly, to pyrimidine derivatives which are effective for systemic lupus erythematosus, a composition for preventing and treating systemic lupus erythematosus comprising the same as an active ingredient and a method for screening the same. The present inventors found novel materials inhibiting surface translocation of gp96 by mimicking a function of AIMP1 which is a molecular anchor for an intracellular residence of gp96, and identified in vitro and in vivo activity of the materials for preventing and treating SLE by alleviating SLE plasma in autoimmune diseases. Therefore, the present invention provides a novel method for screening a therapeutic agent for SLE, and preventing or treating SLE using the mechanism.
摘要翻译：本发明涉及新的2,4-嘧啶衍生物及其用途，更具体地涉及对系统性红斑狼疮有效的嘧啶衍生物，用于预防和治疗包含其作为活性成分的系统性红斑狼疮的组合物和筛选方法本发明人通过模拟作为gp96细胞内宿主的分子锚的AIMP1的功能，发现抑制gp96的表面易位的新型材料，并通过减轻SLE等离子体来预防和治疗SLE的材料的体外和体内活性自身免疫性疾病因此，本发明提供了用于筛选SLE治疗剂以及使用该机制预防或治疗SLE的新方法。

6. 外观设计

USD555602S1 Inverter controller for electric motor 有权
标题翻译：电动机变频器控制器
公开(公告)号：USD555602S1
公开(公告)日：2007-11-20
申请号：US29264548
申请日：2006-08-14
申请人： Kyung Eun Park
设计人： Kyung Eun Park

7. 发明授权

US09966486B2 Solar cell apparatus and method of fabricating the same 有权
公开(公告)号：US09966486B2
公开(公告)日：2018-05-08
申请号：US14123462
申请日：2012-05-30
申请人： Kyung Eun Park
发明人： Kyung Eun Park
IPC分类号： H01L31/0352 , H01L31/032 , H01L31/068 , H01L31/0749 , H01L31/075 , H01L31/061 , H01L31/0468 , H01L31/18
CPC分类号： H01L31/035281 , H01L31/0322 , H01L31/0468 , H01L31/061 , H01L31/068 , H01L31/0749 , H01L31/075 , H01L31/1804 , H01L31/1884 , Y02E10/541 , Y02E10/547 , Y02E10/548 , Y02P70/521
摘要： Disclosed are a solar cell apparatus and a method of fabricating the same. The solar cell apparatus includes a substrate, a first electrode layer on the substrate, a plurality of light absorbing columns on the first electrode layer, and a second electrode layer on the light absorbing columns.

8. 外观设计

USD573945S1 Inverter for electric motor 有权
标题翻译：电动机变频器
公开(公告)号：USD573945S1
公开(公告)日：2008-07-29
申请号：US29264553
申请日：2006-08-14
申请人： Kyung Eun Park
设计人： Kyung Eun Park

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