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1. 发明授权

US5866574A Pancreatitis remedy 失效
标题翻译：胰腺炎补救
公开(公告)号：US5866574A
公开(公告)日：1999-02-02
申请号：US56710
申请日：1998-04-08
申请人： Yuko Okamura , Junichi Shimada , Toru Noji , Chikako Katagiri , Akira Karasawa
发明人： Yuko Okamura , Junichi Shimada , Toru Noji , Chikako Katagiri , Akira Karasawa
IPC分类号： A61K31/517 , A61K31/53 , A61K31/495 , A61K31/505
CPC分类号： A61K31/517
摘要： The present invention relates to a prophylactic agent or a therapeutic agent of pancreatitis, containing an adenosine uptake inhibitor or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明涉及含有腺苷摄取抑制剂或其药学上可接受的盐的胰腺炎的预防剂或治疗剂。

2. 发明授权

US5525607A Xanthine compounds 失效
标题翻译：黄嘌呤化合物
公开(公告)号：US5525607A
公开(公告)日：1996-06-11
申请号：US63684
申请日：1993-05-20
申请人： Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka , Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka
发明人： Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka , Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka
IPC分类号： C07D473/06 , C07D473/08 , C07D473/20 , C07D473/22 , A61K31/52 , C07D473/00
CPC分类号： C07D473/06 , C07D473/08 , C07D473/20 , C07D473/22
摘要： Novel xanthine compounds represented by the following formula: ##STR1## wherein each of R.sup.1, R.sup.2 and R.sup.3 independently represents hydrogen or lower alkyl;each of X.sup.1 and X.sup.2 independently represents oxygen or sulfur; and Q represents: ##STR2## The compounds are useful as a diuretic, a renal-protecting agent and bronchodilator.
摘要翻译：由下式表示的新型黄嘌呤化合物：其中R 1，R 2和R 3各自独立地表示氢或低级烷基; X1和X2各自独立地表示氧或硫; Q表示：该化合物可用作利尿剂，肾保护剂和支气管扩张剂。

3. 发明授权

US5290782A Xanthine derivatives 失效
标题翻译：黄嘌呤衍生物
公开(公告)号：US5290782A
公开(公告)日：1994-03-01
申请号：US839690
申请日：1992-02-24
申请人： Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka
发明人： Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka
IPC分类号： C07D473/06 , C07D473/08 , C07D473/20 , C07D473/22 , C07D473/02 , A61K31/52
CPC分类号： C07D473/06 , C07D473/08 , C07D473/20 , C07D473/22
摘要： Novel xanthine compounds represented by the following formula: ##STR1## wherein each of X.sup.1 and X.sup.2 independently represents oxygen or sulfur; and Q represents; ##STR2## where ----- represents a single bond or a double bond; Y represents a single bond or alkylene, n represents 0 or 1, each of W.sup.1 and W.sup.2 independently represents hydrogen, lower alkyl or amino, Z represents --CH.sub.2 -, --O--, --S-- or --NH--; represents ##STR3## each of R.sup.1 and R.sup.2 independently represents hydrogen, lower alkyl, allyl or propargyl; and R.sup.3 represents hydrogen or lower alkyl, and when Q represents the groups other than ##STR4## each of R.sup.1, R.sup.2 and R.sup.3 independently represents hydrogen or lower alkyl;provided that when Q is ##STR5## then R.sup.1 R.sup.2 and R.sup.3 are notsimultaneously methyl; and pharmaceutically acceptable salts thereof have a diuretic effect, a renal-protecting effect and a bronchodilatory effect.
摘要翻译：由下式表示的新型黄嘌呤化合物：其中X1和X2各自独立地表示氧或硫; 和Q表示; 其中-----表示单键或双键; Y表示单键或亚烷基，n表示0或1，W1和W2各自独立地表示氢，低级烷基或氨基，Z表示-CH2 - ， - O - ， - S-或-NH-。 R1和R2各自表示氢，低级烷基，烯丙基或炔丙基; 且R 3表示氢或低级烷基，并且当Q表示除R1之外的基团时，R 1，R 2和R 3各自独立地表示氢或低级烷基; 条件是当Q为时，则R1 + L，R2和R3不同时为甲基; 及其药学上可接受的盐具有利尿作用，肾脏保护作用和支气管扩张作用。

4. 发明授权

US5270316A Condensed purine derivatives 失效
标题翻译：凝血嘌呤衍生物
公开(公告)号：US5270316A
公开(公告)日：1993-12-14
申请号：US599758
申请日：1990-10-19
申请人： Fumio Suzuki , Junichi Shimada , Takeshi Kuroda , Kazuhiro Kubo , Akira Karasawa , Tetsuji Ohno , Kenji Ohmori
发明人： Fumio Suzuki , Junichi Shimada , Takeshi Kuroda , Kazuhiro Kubo , Akira Karasawa , Tetsuji Ohno , Kenji Ohmori
IPC分类号： A61K31/00 , A61K31/495 , A61K31/505 , A61K31/519 , A61K31/529 , A61P7/00 , A61P7/10 , A61P9/00 , A61P9/12 , A61P11/00 , A61P11/06 , A61P11/08 , A61P13/00 , A61P13/02 , A61P13/12 , A61P15/00 , C07D471/14 , C07D487/14 , A61K31/52
CPC分类号： C07D471/14 , C07D487/14
摘要： There are disclosed condensed purine derivatives represented by formula; ##STR1## in which R.sup.3 represents hydrogen, lower alkyl or benzyl; each of X.sup.1 and X.sup.2 independently represents hydrogen, lower alkyl, aralkyl or phenyl; and n is an integer of 0 or 1; R.sup.1 represents hydrogen, lower alkyl, alicyclic alkyl, noradamantan-3-yl, dicyclopropylmethyl or styryl; and R.sup.2 represents hydrogen, lower alkyl or alicyclic alkyl; or a pharmaceutically acceptable salt thereof. The derivatives and pharmaceutically acceptable salts are useful as diuretics, renal protecting agents, antiallergic agents and hypotensives.

5. 发明授权

US5342841A Xanthine derivatives 失效
标题翻译：黄嘌呤衍生物
公开(公告)号：US5342841A
公开(公告)日：1994-08-30
申请号：US29069
申请日：1993-03-10
申请人： Fumio Suzuki , Junichi Shimada , Akira Karasawa , Hideaki Mizumoto , Hiroshi Kase , Hiromi Nonaka
发明人： Fumio Suzuki , Junichi Shimada , Akira Karasawa , Hideaki Mizumoto , Hiroshi Kase , Hiromi Nonaka
IPC分类号： C07D473/06 , A61K31/52 , C07D473/02
CPC分类号： C07D473/06
摘要： A xanthine derivative of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are substituted or unsubstituted alicyclic alkyl; m1 and m2 are the same or different and represent an integer of 0 to 2; and Q represents ##STR2## (in which R.sup.3 and R.sup.4 are the same or different and are substituted or unsubstituted alicyclic alkyl) or ##STR3## (in which n is 0 or 1, and Y is a single bond or alkylene); or a pharmaceutically acceptable salt thereof is disclosed.This derivative has diuretic activity and renal protecting activity.
摘要翻译：式（I）的黄嘌呤衍生物：其中R1和R2相同或不同，为取代或未取代的脂环族烷基; m1和m2相同或不同，表示0〜2的整数。和Q表示（其中R 3和R 4相同或不同，是取代或未取代的脂环族烷基）或（其中n为0或1，Y为单键或亚烷基）。或其药学上可接受的盐。该衍生物具有利尿活性和肾脏保护活性。

6. 发明授权

US5068236A Xanthine derivatives 失效
标题翻译： XANTHINE DERIVATIVES
公开(公告)号：US5068236A
公开(公告)日：1991-11-26
申请号：US486831
申请日：1990-03-01
申请人： Fumio Suzuki , Junichi Shimada , Kazuhiro Kubo , Tetsuji Ohno , Akira Karasawa , Akio Ishii , Hiromi Nonaka
发明人： Fumio Suzuki , Junichi Shimada , Kazuhiro Kubo , Tetsuji Ohno , Akira Karasawa , Akio Ishii , Hiromi Nonaka
IPC分类号： A61K31/52 , A61K31/522 , A61P7/10 , A61P9/08 , A61P9/12 , A61P13/02 , A61P15/00 , C07D473/04 , C07D473/06 , C07D473/08 , C07D473/10 , C07D473/12 , C07D473/20 , C07D473/22
CPC分类号： C07D473/04 , C07D473/06 , C07D473/22
摘要： Novel xanthine compounds represented by the following formula: ##STR1## and pharmaceutically acceptable salts thereof have a diuretic action, a renal-protecting action and a vasodilative action.The compounds are useful as a diuretic, a renal-protecting agent and an antihypertensive agent.

7. 发明授权

US5173492A s-Triazolo(3,4-I)purine derivatives 失效
标题翻译：三唑并（3,4-I）嘌呤衍生物
公开(公告)号：US5173492A
公开(公告)日：1992-12-22
申请号：US752180
申请日：1991-08-23
申请人： Fumio Suzuki , Junichi Shimada , Kenji Ohmori , Haruhiko Manabe , Kazuihiro Kubo , Akira Karasawa , Tetsuji Ohno , Shizuo Shiozaki , Akio Ishii , Katsuichi Shuto
发明人： Fumio Suzuki , Junichi Shimada , Kenji Ohmori , Haruhiko Manabe , Kazuihiro Kubo , Akira Karasawa , Tetsuji Ohno , Shizuo Shiozaki , Akio Ishii , Katsuichi Shuto
IPC分类号： C07D471/14
CPC分类号： C07D471/14
摘要： There are disclosed s-triazolo[3,4-i]purine derivatives represented by formula: ##STR1## wherein Y-Z represents ##STR2## R.sub.4 represents hydrogen, alkyl, substituted or unsubstituted aromatic heterocyclic group or substituted or unsubstituted aryl; and X.sup.2 represents oxygen, sulfur or NH; each of R.sup.1 and R.sup.2 independently represents hydrogen, alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; R.sup.3 represents alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; X.sup.1 represents oxygen or sulfur; and represents a single bond or a double bond or pharmaceutically acceptable salts thereof.
摘要翻译：公开了由下式表示的三唑并[3,4-i]嘌呤衍生物：其中Y-Z表示R 4表示氢，烷基，取代或未取代的芳族杂环基或取代或未取代的芳基; X2表示氧，硫或NH; R 1和R 2各自独立地表示氢，烷基，环烷基，芳烷基或取代或未取代的芳基; R3表示烷基，环烷基，芳烷基或取代或未取代的芳基; X1表示氧或硫; 并且表示单键或双键或其药学上可接受的盐。

8. 发明申请

US20130033048A1 VEHICLE COLLISION PROTECTION APPARATUS 有权
标题翻译：车辆碰撞保护装置
公开(公告)号：US20130033048A1
公开(公告)日：2013-02-07
申请号：US13641592
申请日：2011-04-28
申请人： Hiroshi Oyama , Junichi Shimada , Mikito Sawaki
发明人： Hiroshi Oyama , Junichi Shimada , Mikito Sawaki
IPC分类号： B60R19/24
CPC分类号： B62D25/082 , B60H1/2209 , B60H2001/2293 , B62D21/152
摘要： A vehicle collision protection apparatus includes a bracket. The bracket includes a deflecting force generating component provided at a rear end of the bracket. The bracket is disposed in a vehicle front space of a vehicle and extends in a front to rear direction of the vehicle and attach a vehicle component to a body of the vehicle. The deflecting force generating component deflects the rear end of the bracket in a width direction of the vehicle and rotates the bracket together with the vehicle component in the width direction when the deflecting force generating component impinges against a portion of the vehicle body as the rear end of the bracket is displaced in a rearward direction of the vehicle due to crushing of a front end of the vehicle during a collision at the front end of the vehicle.
摘要翻译：车辆碰撞保护装置包括支架。支架包括设置在支架后端的偏转力产生部件。支架设置在车辆的车辆前部空间中，并且在车辆的前后方向上延伸，并且将车辆部件附接到车辆的车身。偏转力产生部件在车辆的宽度方向使托架的后端偏转，并且当偏转力产生部件碰撞车体的一部分时，作为后端部而使车架部件沿宽度方向旋转支架由于在车辆的前端碰撞期间车辆的前端被破坏，托架在车辆的后方向上移位。

9. 发明授权

US07834434B2 LED illumination system 有权
标题翻译： LED照明系统
公开(公告)号：US07834434B2
公开(公告)日：2010-11-16
申请号：US12149570
申请日：2008-05-05
申请人： Junichi Shimada , Yoichi Kawakami
发明人： Junichi Shimada , Yoichi Kawakami
IPC分类号： H01L23/495
CPC分类号： F21V23/06 , F21K9/20 , F21V29/505 , F21Y2115/10 , H01L25/0753 , H01L33/641 , H01L2924/0002 , H01L2924/00
摘要： The present invention is achieved with the object of providing an illumination system formed of an LED light emitting body and a socket which can appropriately release heat from LED chips. This object is achieved in the following manner. A heat conducting layer 12 made of diamond is provided on a substrate 11, and on top of this, a conductive layer 13 having a predetermined pattern is formed. LED chips 16 are mounted in predetermined positions on the conductive layer 13. Terminals of the conductive layer 13 and electrodes of the LED chips 16 are connected to each other. A connector part 14 for the connection to a socket is provided in an end portion of the substrate 11. The heat conducting layer 12 on the connector part 14 makes thermal contact with the heat conducting layer provided on the inner surface of the opening of the socket. A current is supplied to respective LED chips 16 through the conductive layer 13 from the socket, and respective LED chips 16 emit light. Heat that is generated in the LED chips 16 is released to the outside of the illumination system from the socket through the conductive layer 13, the heat conducting layer 12 and the connector part 14. As a result of this, an increase in the temperature of the LED chips 16 can be prevented, and an LED illumination system that emits a large amount of light can be formed.
摘要翻译：本发明的目的是提供一种由LED发光体和能够适当地从LED芯片释放热量的插座形成的照明系统。该目的以如下方式实现。在基板11上设置由金刚石制成的导热层12，并且在其上形成具有预定图案的导电层13。 LED芯片16安装在导电层13上的预定位置。导电层13的端子和LED芯片16的电极彼此连接。用于连接到插座的连接器部分14设置在基板11的端部。连接器部分14上的导热层12与设置在插座的开口的内表面上的导热层热接触。从插座通过导电层13向相应的LED芯片16提供电流，并且各个LED芯片16发光。在LED芯片16中产生的热量通过导电层13，导热层12和连接器部分14从插座释放到照明系统的外部。其结果是，可以防止LED芯片16，并且可以形成发射大量光的LED照明系统。

10. 发明授权

US07445256B2 Automotive door latch device 有权
标题翻译：汽车门锁装置
公开(公告)号：US07445256B2
公开(公告)日：2008-11-04
申请号：US11188883
申请日：2005-07-26
申请人： Shingo Gotou , Junichi Shimada , Hirotsugu Takai , Takashi Ogawa
发明人： Shingo Gotou , Junichi Shimada , Hirotsugu Takai , Takashi Ogawa
IPC分类号： E05C3/06 , E05C3/00
CPC分类号： E05B85/02 , E05B63/0056 , E05B77/265 , E05B77/30 , E05B77/34 , E05B81/06 , E05B81/16 , E05B81/34 , E05B2015/1664 , Y10S292/23 , Y10T292/1047 , Y10T292/1082
摘要： An actuating assembly for an automotive door latch device comprises a housing that operatively installs therein basic elements that are commonly used in an override function unit and a child proof function unit. The override function unit has a function wherein a manipulation of an inside door handle induces cancellation of the engaged condition of the latch means irrespective of the condition of the locking/unlocking means. The child proof function unit has a function wherein the manipulation of the inside door handle is made inoperative irrespective of the condition of the locking/unlocking means, thereby to make the cancellation of the engaged condition of the latch means impossible. The actuating assembly further comprises a cover that is coupled to the housing and holds thereon a selected element that is exclusively used in either one of the override function unit and the child proof function unit.
摘要翻译：用于汽车门闩锁装置的致动组件包括：壳体，其可操作地安装在超控功能单元和儿童防护功能单元中通常使用的基本元件。超控功能单元具有这样的功能，其中，无论锁定/解锁装置的状况如何，内部门把手的操纵都会导致锁定装置的接合状态的消除。防儿功能单元具有这样的功能，其中无论锁定/解锁装置的状况如何，内门把手的操作都不起作用，从而使闩锁装置的接合状态的消除是不可能的。所述致动组件还包括盖，所述盖联接到所述壳体并且在其上保持专用于所述超驰功能单元和所述儿童防护功能单元中的任一个的选定元件。

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