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    • 4. 发明申请
    • SYSTEM AND METHOD FOR PROVIDING DOCUMENT BASED ON PERSONAL NETWORK
    • 基于个人网络提供文档的系统和方法
    • US20120084318A1
    • 2012-04-05
    • US13239102
    • 2011-09-21
    • In Ho KANGSoo Hyun KIMChan Hoon PARK
    • In Ho KANGSoo Hyun KIMChan Hoon PARK
    • G06F17/30
    • G06F17/30011G06Q10/10
    • Provided are a system and method for providing a document based on a personal network. The document providing system may include a community searching unit to search for a community associated with a first document prepared by a first user, a document registration unit to register the first document in the searched community, and to receive a second document, associated with the first document, registered by a second user included in the community, and a document providing unit to provide the second document associated with the first document. According to embodiments of the present invention, a response that the first user may desire may be provided by receiving a response, registered by the second user included in the community associated with the first user, with respect to the document prepared by the first user.
    • 提供了一种用于提供基于个人网络的文档的系统和方法。 文档提供系统可以包括:社区搜索单元,用于搜索与由第一用户准备的第一文档相关联的社区,文档注册单元,用于在搜索到的社区中注册第一文档,以及接收与第一文档相关联的第二文档 第一文件,由包括在社区中的第二用户注册,以及文档提供单元,用于提供与第一文档相关联的第二文档。 根据本发明的实施例,可以通过从第一用户准备的文档接收包括在与第一用户相关联的社区中的第二用户注册的响应来提供第一用户可能希望的响应。
    • 10. 发明申请
    • METHOD FOR THE PREPARATION OF TUBE-TYPE POROUS BIODEGRADABLE SCAFFOLD HAVING DOUBLE-LAYERED STRUCTURE FOR VASCULAR GRAFT
    • 用于制备具有双层结构的管状多孔生物可降解SCAFFO的方法
    • US20090012607A1
    • 2009-01-08
    • US11952759
    • 2007-12-07
    • Sang-Heon KIMSoo Hyun KIMEunna CHUNG
    • Sang-Heon KIMSoo Hyun KIMEunna CHUNG
    • A61F2/82B29C70/32
    • B29C70/32A61F2/06A61F2210/0004D01D5/0007D01D5/04
    • Disclosed herein are a tube-type porous scaffold having a double-layered structure for use as an artificial vascular graft and a preparation method thereof. The method comprises (1) dissolving a biodegradable polymer in an organic solvent and mixing the polymer with a porogen so as to provide a polymer/porogen mixture; (2) coating a cylindrical shaft with the polymer/porogen mixture so as to form an inner porous coating layer; (3) preparing a biodegradable polymer gel by dissolving a biodegradable polymer in an organic solvent; (4) spinning down the biodegradable polymer gel in a non-solvent coagulation bath in which the cylindrical shaft having the inner porous coating layer, obtained at step (2), is immersed and rotated to form gel-phase fibers and allowing the gel-phase fibers to wind around the inner porous coating layer of the rotating shaft so as to form an outer polymer fibrous layer; and (5) separating the double-layered porous scaffold, formed on the shaft, from the shaft and removing the organic solvent and the porogen from the scaffold. Since the porous scaffold has a double-layered structure consisting of an inner porous coating layer containing micropores and a gel-phase outer polymer fibrous layer, it has high pore interconnectivity and mechanical strength, which effectively prevents the leakage of blood, and has high cell seeding and proliferation efficiencies, thereby being useful as a tissue-engineered artificial vascular graft.
    • 本文公开了具有用作人造血管移植物的双层结构的管型多孔支架及其制备方法。 该方法包括(1)将可生物降解的聚合物溶解在有机溶剂中并将该聚合物与致孔剂混合以提供聚合物/致孔剂混合物; (2)用聚合物/致孔剂混合物涂覆圆柱形轴以形成内部多孔涂层; (3)通过将可生物降解的聚合物溶解在有机溶剂中制备可生物降解的聚合物凝胶; (4)在非溶剂凝固浴中将可生物降解的聚合物凝胶纺丝,其中将具有内部多孔涂层的圆柱形轴在步骤(2)中浸渍并旋转以形成凝胶相纤维, 缠绕在旋转轴的内部多孔涂层周围,以形成外部聚合物纤维层; 和(5)将形成在轴上的双层多孔支架从轴上分离并从支架中除去有机溶剂和致孔剂。 由于多孔支架具有由含有微孔的内多孔涂层和凝胶相外聚合物纤维层组成的双层结构,因此具有高孔互连性和机械强度,有效防止血液渗漏,并具有高细胞 播种和增殖效率,从而可用作组织工程人造血管移植物。