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1. 发明授权

US07341864B2 Molecule transferring device, auxiliary for molecule transferring device, and molecule transferring method 有权
标题翻译：分子转移装置，分子转移装置辅助剂和分子转移方法
公开(公告)号：US07341864B2
公开(公告)日：2008-03-11
申请号：US10182262
申请日：2001-01-29
申请人： Yoshitaka Sakamoto , Masafumi Koide , Juichiro Nakashima , Susumu Satoh , Sousuke Miyoshi , Akiko Suzuki , Hiroyuki Arakawa , Hiroshi Marusawa
发明人： Yoshitaka Sakamoto , Masafumi Koide , Juichiro Nakashima , Susumu Satoh , Sousuke Miyoshi , Akiko Suzuki , Hiroyuki Arakawa , Hiroshi Marusawa
IPC分类号： C12M1/42 , C12M3/00 , C12N13/00 , C12N15/87 , C12N15/82
CPC分类号： C12N15/87 , A61K48/00 , A61K48/0083 , C12M35/02
摘要： A molecule introducing apparatus is provided with a power supply circuit 20 for supplying power, a step-up transformer 30 which is supplied with power from the power supply circuit 20 and which outputs a high voltage, a switching transistor 22 that blocks off and allows the supply of power from the power supply circuit 20 to the step-up transformer 30 and which generates an instantaneous high voltage, and a pair of electrode probes 50 for applying the instantaneous high voltage generated at the step-up transformer 30 to a predetermined region in a body. The molecule introducing apparatus oscillates DNA arranged outside a cell by the instantaneous high voltage so as to introduce the DNA into the cell.
摘要翻译：分子引入装置设置有用于供电的电源电路20，从电源电路20提供电力并输出高电压的升压变压器30，截止的开关晶体管22，从电源电路20向升压变压器30供电并产生瞬时高电压;以及一对电极探针50，用于将升压变压器30产生的瞬时高压施加到预定区域身体。分子导入装置通过瞬时高电压振荡排列在细胞外的DNA，以将DNA引入细胞。

2. 发明申请

US20050159682A1 Molecule vibrator 审中-公开
标题翻译：分子振子
公开(公告)号：US20050159682A1
公开(公告)日：2005-07-21
申请号：US10504067
申请日：2003-02-12
申请人： Masafumi Koide , Yoshitaka Sakamoto , Takaji Mizuno
发明人： Masafumi Koide , Yoshitaka Sakamoto , Takaji Mizuno
IPC分类号： C12M1/42 , C12M3/00 , C12N13/00 , A61H1/00
CPC分类号： C12N13/00 , C12M35/02
摘要： A voltage generation circuit (20) is provided which generates a voltage. A voltage application circuit (30) is provided which has electrodes (11, 12) which are fed a respective voltage for causing creation of an instantaneous high electric field in a region of interest as a target such as a living body tissue or cell. The voltage application circuit (30) is high-impedanced for excitation of a free resonant circuit including the target. It is arranged such that the relative position of the target with respect to one of the electrodes (11, 12) is adjustable.
摘要翻译：提供产生电压的电压产生电路（20）。提供一种电压施加电路（30），其具有电极（11,12），该电极被馈送各自的电压，以在感兴趣的区域中产生作为目标的诸如生物体组织或细胞的瞬时高电场。电压施加电路（30）对于包括目标的自由谐振电路的激励是高阻抗的。它被布置成使得靶相对于电极（11,12）之一的相对位置是可调节的。

3. 发明授权

US09329104B2 Tire testing device 有权
标题翻译：轮胎测试装置
公开(公告)号：US09329104B2
公开(公告)日：2016-05-03
申请号：US14127571
申请日：2012-03-22
申请人： Masafumi Koide
发明人： Masafumi Koide
IPC分类号： G01M17/02
CPC分类号： G01M17/022
摘要： An object of the present invention is to provide an inside drum-type tire testing device, which can significantly improve operability and test precision, reliably has strength high enough to eliminate any concern about strength thereof, and has relatively small size and significantly small floor-occupied area. Specifically, the present invention provides a tire testing device, comprising: an inside drum-type cylindrical rotating drum 1; a fixed support member 2 for surrounding the rotating drum 1 from the outer peripheral side of the drum via rotation guide means 3; and a linear motor 4 provided between the rotating drum 1 and the fixed support member 2, for rotationally driving the rotating drum 1.
摘要翻译：本发明的目的是提供一种能够显着提高可操作性和测试精度的内鼓式轮胎测试装置，可靠地具有足够高的强度以消除对其强度的任何影响，并且具有相对小的尺寸和显着小的底板 - 占领区。具体地说，本发明提供一种轮胎试验装置，其特征在于，包括：内筒型筒状旋转滚筒1; 用于经由旋转引导装置3从滚筒的外周侧围绕旋转滚筒1的固定支撑构件2; 以及设置在旋转滚筒1和固定支撑构件2之间用于旋转地驱动旋转滚筒1的线性马达4。

4. 发明申请

US20070141576A1 Biological chip and use thereof 审中-公开
标题翻译：生物芯片及其用途
公开(公告)号：US20070141576A1
公开(公告)日：2007-06-21
申请号：US10582526
申请日：2004-12-13
申请人： Masafumi Koide
发明人： Masafumi Koide
IPC分类号： C12Q1/68 , C12M3/00
CPC分类号： G01N35/00069 , B01L3/508 , B01L2300/0636 , B01L2300/0841
摘要： A biological chip includes probes immobilized on a circumferential side wall of a discoidal or cylindrical substrate. The probes contain a nucleic acid, a peptide, a saccharide, a lipid, a chemical substance, or a fragment thereof. The disc or cylinder is rotated so as to attain rapid intake of massive assay information obtained from plural probe groups arranged on the circumferential side wall. Mass production of a lot of chips or large-capacity chips is accomplished by constructing the disc or cylinder from a large number of thin sheets or through lamination of plural thin sheets. In blood tests, a biological chip having incubation cells arranged thereon realizes system simplification and miniaturization and resource savings.
摘要翻译：生物芯片包括固定在盘状或圆柱形基底的圆周侧壁上的探针。探针含有核酸，肽，糖，脂质，化学物质或其片段。旋转盘或圆筒，以便快速摄取从设置在周向侧壁上的多个探针组获得的大量测定信息。大量生产大量芯片或大容量芯片是通过从大量薄片构成圆盘或圆柱体，或通过层压多个薄片来实现的。在血液检查中，具有布置在其上的孵育细胞的生物芯片实现了系统简化和小型化以及资源节约。

5. 发明申请

US20100282391A1 PNEUMATIC TIRE 有权
标题翻译：气动轮胎
公开(公告)号：US20100282391A1
公开(公告)日：2010-11-11
申请号：US12863649
申请日：2008-01-24
申请人： Makoto Ishiyama , Masafumi Koide
发明人： Makoto Ishiyama , Masafumi Koide
IPC分类号： B60C9/18 , B60C9/28 , B60C3/04
CPC分类号： B60C9/26 , B60C9/2009 , B60C9/28 , B60C11/0083 , B60C2011/0025 , Y10T152/10765 , Y10T152/10801
摘要： Since a protecting layer 43 embedded with reinforcing cords 41 is disposed between a tread 35 and a belt reinforcing layer 31, both of the protecting layer 43 and the belt reinforcing layer 31 decentrally bear a large bending force generated when a pneumatic tire 11 runs on a sharp projection or a difference in level. As a result, even if reinforcing elements 33 in the belt reinforcing layer 31 are extended by large tension due to fill internal pressure, increase of strain generated in the reinforcing elements 33 can be effectively suppressed.
摘要翻译：由于嵌入加强帘线41的保护层43设置在胎面35和带束层31之间，所以保护层43和带束层增强层31都分散地承受当充气轮胎11在其上运行时产生的大的弯曲力尖锐的投影或水平的差异。结果，即使由于填充内压而使带束增强层31中的增强元件33延伸大张力，也能够有效地抑制增强元件33产生的应变的增加。

6. 发明申请

US20090008017A1 Pneumatic Tire 审中-公开
标题翻译：气动轮胎
公开(公告)号：US20090008017A1
公开(公告)日：2009-01-08
申请号：US11813750
申请日：2005-11-30
申请人： Takashi Kawai , Masafumi Koide , Makoto Ishiyama
发明人： Takashi Kawai , Masafumi Koide , Makoto Ishiyama
IPC分类号： B60C9/18
CPC分类号： B60C9/22 , B60C9/2009 , Y10T152/10765 , Y10T152/10783
摘要： There is provided a pneumatic tire in which a belt reinforcement layer is placed and capable of increasing both riding comfort and steering stability. Circumferential bending rigidity of a contact belt ply 25 placed in contact with the belt reinforcement layer 35 is made higher than circumferential bending rigidity of a remote belt ply 24, and thus the belt reinforcement layer 35 having high circumferential bending rigidity and the contact belt ply 25 having next high circumferential bending rigidity are collected near a neutral axis of bending positioned near a boundary thereof. Thus, composite circumferential bending rigidity of the belt layer 23 and the belt reinforcement layer 35 is reduced to reduce a vertical spring constant of the pneumatic tire 11 and increase a ground contact length.
摘要翻译：提供了一种充气轮胎，其中设置了带加强层，并且能够增加乘坐舒适性和操纵稳定性。与带加强层35接触的接触带束层25的周向弯曲刚性高于远侧带束层24的周向弯曲刚度，因此具有高周向弯曲刚度的带束加强层35和接触带层25 在靠近其边界的中立弯曲中心附近收集具有下一个高周向弯曲刚度的装置。因此，带束层23和带束加强层35的复合周向弯曲刚性减小，以减小充气轮胎11的垂直弹簧常数并增加接地长度。

7. 发明申请

US20050146066A1 Porous ceramic and method for production thereof 审中-公开
标题翻译：多孔陶瓷及其制造方法
公开(公告)号：US20050146066A1
公开(公告)日：2005-07-07
申请号：US10512224
申请日：2003-04-28
申请人： Masafumi Koide , Eiichi Tsuchihira
发明人： Masafumi Koide , Eiichi Tsuchihira
IPC分类号： C04B33/24 , C04B33/32 , C04B35/632 , C04B35/636 , C04B38/00 , C04B38/06
CPC分类号： C04B35/636 , C04B33/24 , C04B35/632 , C04B38/0645 , C04B2111/00793 , C04B2235/449 , C04B35/00 , C04B38/007 , C04B40/0075 , C04B40/0089 , C04B33/00
摘要： The method for producing a porous ceramic comprises the slurry preparing step of preparing a slurry containing a powdery aggregate and a hydrated crystalline material having a burn-out feature, the solid matter forming step of decreasing a liquid component from the slurry prepared in the slurry preparing step, thereby forming a solid matter, and the firing step of firing the solid matter formed in the solid matter forming step to burn up the hydrated crystalline material, thereby forming the porous ceramic.
摘要翻译：制造多孔陶瓷的方法包括制备含有粉状骨料和具有烧成特征的水合结晶材料的浆料的浆料制备步骤，该固体成型步骤从在浆料中制备的浆料中减少液体组分从而形成固体物质，以及烧成在固体成型工序中形成的固体物质的烧成工序，使其水化结晶物质燃烧，从而形成多孔质陶瓷。

10. 发明授权

US08127813B2 Pneumatic tire for two-wheeled vehicle 有权
标题翻译：双轮车气动轮胎
公开(公告)号：US08127813B2
公开(公告)日：2012-03-06
申请号：US12093255
申请日：2006-11-10
申请人： Shinsaku Katayama , Makoto Ishiyama , Masafumi Koide , Takashi Kawai
发明人： Shinsaku Katayama , Makoto Ishiyama , Masafumi Koide , Takashi Kawai
IPC分类号： B60C1/00 , B60C11/00
CPC分类号： B60C9/2204 , B60C11/00 , B60C11/0058 , B60C2011/0025 , B60C2200/10
摘要： The pneumatic tire for two-wheeled vehicles including a plurality of tread rubbers constituting a tread wherein a region occupying 15 to 35% in the center of a stretched tread width, which is obtained by stretching the tread with respect to a tire equatorial plane as the center, is defined as a tread central section; the remaining regions at both ends are defined as tread side sections; regions in the respective tread side sections each occupying 4 to 13% from the corresponding tread end toward the center of the stretched tread width are defined as side-section shoulder-end regions; and the remaining regions of the respective tread side sections are defined as side-section near-center regions, a modulus of the tread rubbers for the side-section shoulder-end regions at 100% elongation is smaller than a modulus of the tread rubbers for the side-section near-center regions at 100% elongation, at least at a tread surface.
摘要翻译：一种两轮车辆用充气轮胎，其特征在于，具有构成胎面的多个胎面橡胶，其中，在胎面宽度的中心处占据15〜35％的区域，所述胎面橡胶相对于轮胎赤道面拉伸为胎面中心，被定义为胎面中心部分; 两端的其余区域被定义为胎面侧段; 相应的胎面侧部分中的相应的胎面端部朝向拉伸的胎面宽度的中心占据4至13％的区域被定义为侧部肩端部区域; 各胎面侧部分的剩余区域被定义为侧面近中心区域，在100％伸长率下，侧部胎肩端部区域的胎面橡胶的模量小于胎面橡胶的模量，至少在胎面表面处的100％伸长率的侧面近中心区域。

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