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1. 发明授权

US5514711A Styrene derivatives 失效
标题翻译：苯乙烯衍生物
公开(公告)号：US5514711A
公开(公告)日：1996-05-07
申请号：US369263
申请日：1995-01-05
申请人： Yasunori Kitano , Hisao Takayanagi , Koichi Sugawara , Hiroto Hara , Hideo Nakamura , Toshiko Oshino
发明人： Yasunori Kitano , Hisao Takayanagi , Koichi Sugawara , Hiroto Hara , Hideo Nakamura , Toshiko Oshino
IPC分类号： A61K31/16 , A61K31/165 , A61K31/255 , A61K31/275 , A61P35/00 , C07C45/45 , C07C45/54 , C07C45/56 , C07C45/71 , C07C47/575 , C07C49/248 , C07C49/835 , C07C49/84 , C07C59/48 , C07C69/73 , C07C69/84 , C07C235/38 , C07C255/36 , C07C255/40 , C07C255/41 , C07C255/42 , C07C255/56 , C07C255/57 , C07C255/58 , C07C317/46 , C07C255/34
CPC分类号： C07C45/45 , C07C255/40 , C07C255/41 , C07C317/46 , C07C45/54 , C07C45/562 , C07C45/71 , C07C47/575 , C07C49/835 , C07C49/84
摘要： Styrene derivatives of the following general formula (I): ##STR1## or pharmaceutically acceptable salts thereof. A pharmaceutical composition useful as anticancer agent, which comprises the above compound as an essential component, is also provided.
摘要翻译：下列通式（I）的苯乙烯衍生物：其中（I）或其药学上可接受的盐。还提供了可用作抗癌剂的药物组合物，其包含上述化合物作为必需组分。

2. 发明授权

US06239150B1 Penicillaminamide derivatives 失效
标题翻译：青霉胺衍生物
公开(公告)号：US06239150B1
公开(公告)日：2001-05-29
申请号：US08983321
申请日：1998-03-12
申请人： Masahiro Oshima , Norimichi Iwase , Naoto Inakoshi , Koichi Sugawara , Misao Okitsu
发明人： Masahiro Oshima , Norimichi Iwase , Naoto Inakoshi , Koichi Sugawara , Misao Okitsu
IPC分类号： C07D20716
CPC分类号： C07K5/0606 , A61K38/00
摘要： Compounds represented by the general formula (I) wherein n represents 1 or 2; R1 represents, for example, a C1-C10 alkyl group which may be substituted with a C3-C10 cycloalkyl group or carboxyl group; R2 represents hydrogen atom, a C1-C10 alkyl group or other; and R3 represents amino group or amidino group, whose example include trans-4-amino-[(S)-N-[(S)-2-propoxycarbonylamino-3-isopropylthio-3-methyl-butanoyl]prolyl]aminomethylcyclohexane. The compounds have potent inhibitory activity against thrombin, and are useful as anticoagulants.
摘要翻译：由通式（I）表示的化合物，其中n表示1或2; R1表示例如可被C 3 -C 10环烷基或羧基取代的C 1 -C 10烷基; R2表示氢原子，C1-C10烷基或其他; 并且R 3表示氨基或脒基，其实例包括反式-4-氨基 - [（S）-N - [（S）-2-丙氧基羰基氨基-3-异丙硫基-3-甲基 - 丁酰基]脯氨酰基]氨基甲基环己烷。这些化合物对凝血酶具有有效的抑制活性，可用作抗凝剂。

3. 发明授权

US5744487A Prolineamide derivatives 失效
标题翻译：脯氨酰胺衍生物
公开(公告)号：US5744487A
公开(公告)日：1998-04-28
申请号：US378615
申请日：1995-01-26
申请人： Masahiro Ohshima , Norimichi Iwase , Shigeo Sugiyama , Koichi Sugawara , Misao Okitsu , Yoshikuni Tamao , Yasuhiro Morinaka
发明人： Masahiro Ohshima , Norimichi Iwase , Shigeo Sugiyama , Koichi Sugawara , Misao Okitsu , Yoshikuni Tamao , Yasuhiro Morinaka
IPC分类号： A61K38/00 , C07D207/16 , C07D211/60 , C07D401/12 , C07D405/12 , C07D409/06 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/072 , A61K31/40 , C07D207/09
CPC分类号： C07D401/12 , C07D207/16 , C07D211/60 , C07D405/12 , C07D409/06 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06113 , C07K5/06191 , A61K38/00
摘要： A prolineamide derivative represented by the formula (I): ##STR1## or a salt or hydrate thereof or a pharmaceutically acceptable salt thereof, which has a protease inhibition activity and is useful as an active ingredient of pharmaceutical compositions is provided.
摘要翻译：提供了具有蛋白酶抑制活性并可用作药物组合物的活性成分的由式（I）表示的脯氨酰胺衍生物：其中（I）或其盐或水合物或其药学上可接受的盐。

4. 发明申请

US20080313965A1 OPENING AND CLOSING DEVICE 有权
标题翻译：打开和关闭装置
公开(公告)号：US20080313965A1
公开(公告)日：2008-12-25
申请号：US12135625
申请日：2008-06-09
申请人： Koichi Sugawara
发明人： Koichi Sugawara
IPC分类号： E05D15/16 , E05D15/00
CPC分类号： E05F15/40 , E05F15/695 , E05Y2400/356 , E05Y2400/854 , E05Y2400/86 , E05Y2800/426 , E05Y2900/55
摘要： An opening and closing device opens and closes a shielding body that partitions space by the operation of an operating unit in a range between a fully opened position and a fully closed position. The opening and closing device includes a limit setting unit, a control unit, and an operating element. The limit setting unit can perform an operation for setting an operational limit position of the shielding body. The control unit sets a range, where the shielding body can be opened and closed by the operation of the operating unit, as a predetermined range between the set operational limit position and a fully closed position or between the set operational limit position and a fully opened position. The operating element operates the control unit so that the range where the shielding body is opened and closed is set to the predetermined range.
摘要翻译：打开和关闭装置打开和关闭屏蔽体，该屏蔽体通过操作单元的操作在完全打开位置和完全关闭位置之间的范围内分隔空间。打开和关闭装置包括限制设定单元，控制单元和操作元件。极限设定单元可以执行用于设定屏蔽体的操作极限位置的操作。控制单元设置一个范围，其中屏蔽体可以通过操作单元的操作而被打开和关闭，作为设定的操作极限位置和完全关闭位置之间或设定的操作极限位置和完全打开之间的预定范围位置。操作元件操作控制单元，使得屏蔽体打开和关闭的范围被设定在预定范围。

5. 发明授权

US4473775A Cathode-ray tube device 失效
标题翻译：阴极射线管装置
公开(公告)号：US4473775A
公开(公告)日：1984-09-25
申请号：US298993
申请日：1981-09-03
申请人： Kakuichiro Hosokoshi , Shigeya Ashizaki , Koichi Sugawara , Masao Natsuhara
发明人： Kakuichiro Hosokoshi , Shigeya Ashizaki , Koichi Sugawara , Masao Natsuhara
IPC分类号： H01J29/48 , H01J29/50 , H01J29/56 , H01J29/46
CPC分类号： H01J29/503 , H01J29/56
摘要： An auxiliary grid which is formed with one or more elongated slits through which pass electron beams is disposed in a prefocusing system in a cathode-ray tube, and a dynamic voltage which varies in level with increase in horizontal deflection angle is applied to the auxiliary grid so that axial asymmetry of the prefocusing system can be increased with increase in the horizontal deflection angle. As a consequence, the beam spot can be maintained substantially in the form of a true circle not only at the center of the screen but also at the portions adjacent to the peripheries thereof. Thus, the resolution at the portions adjacent to the peripheries of the screen can be improved and consequently high-quality images can be represented over the whole surface of the screen.
摘要翻译：辅助栅格，其形成有一个或多个细长狭缝，通过电子束通过该狭缝设置在阴极射线管中的预聚焦系统中，并且随着水平偏转角的增加而在水平上变化的动态电压被施加到辅助栅格从而可以随着水平偏转角的增加而增加预聚焦系统的轴向不对称性。结果，不仅在屏幕的中心，而且在与其周边相邻的部分，束斑可以基本保持为真圆的形式。因此，可以提高与屏幕周边相邻部分的分辨率，从而可以在屏幕的整个表面上显示高质量的图像。

6. 发明授权

US6117897A 1/2 sulfate of a [(S) -1- [(S) -2- [(trans-4- aminocyclohexylmethyl) carbamoyl]pyrrolidine-1-carbonyl]- 2-isopropylthio-2-methylpropyl]carbamic acid propyl ester 有权
标题翻译： [（S）-1 - [（S）-2 - [（反式-4-氨基环己基甲基）氨基甲酰基]吡咯烷-1-羰基] -2-异丙硫基-2-甲基丙基]氨基甲酸丙酯的1/2硫酸盐
公开(公告)号：US6117897A
公开(公告)日：2000-09-12
申请号：US195219
申请日：1998-11-18
申请人： Norimichi Iwase , Naoto Inakoshi , Koichi Sugawara , Jun Anabuki
发明人： Norimichi Iwase , Naoto Inakoshi , Koichi Sugawara , Jun Anabuki
IPC分类号： A61K38/00 , C07D207/16 , C07K5/062 , A01N43/36
CPC分类号： C07K5/0606 , C07D207/16 , A61K38/00
摘要： A 1/2 sulfate of a [(S)-1-[(S)-2-[(trans-4-aminocyclohexylmethyl) carbamoyl]pyrrolidine-1-carbonyl]-2-isopropylthio-2-methylpropyl]carbamic acid propyl ester represented by the following formula (I): a hydrate or solvate thereof.
摘要翻译： [（S）-1 - [（S）-2 - [（反式-4-氨基环己基甲基）氨基甲酰基]吡咯烷-1-羰基] -2-异丙硫基-2-甲基丙基]氨基甲酸丙酯的1/2硫酸盐由下式（I）表示：其水合物或溶剂化物。

7. 发明授权

US07914065B2 Opening and closing device 有权
标题翻译：开闭装置
公开(公告)号：US07914065B2
公开(公告)日：2011-03-29
申请号：US12135625
申请日：2008-06-09
申请人： Koichi Sugawara
发明人： Koichi Sugawara
IPC分类号： B60J1/12
CPC分类号： E05F15/40 , E05F15/695 , E05Y2400/356 , E05Y2400/854 , E05Y2400/86 , E05Y2800/426 , E05Y2900/55
摘要： An opening and closing device opens and closes a shielding body that partitions space by the operation of an operating unit in a range between a fully opened position and a fully closed position. The opening and closing device includes a limit setting unit, a control unit, and an operating element. The limit setting unit can perform an operation for setting an operational limit position of the shielding body. The control unit sets a range, where the shielding body can be opened and closed by the operation of the operating unit, as a predetermined range between the set operational limit position and a fully closed position or between the set operational limit position and a fully opened position. The operating element operates the control unit so that the range where the shielding body is opened and closed is set to the predetermined range.
摘要翻译：打开和关闭装置打开和关闭屏蔽体，该屏蔽体通过操作单元的操作在完全打开位置和完全关闭位置之间的范围内分隔空间。打开和关闭装置包括限制设定单元，控制单元和操作元件。极限设定单元可以执行用于设定屏蔽体的操作极限位置的操作。控制单元设置一个范围，其中屏蔽体可以通过操作单元的操作而被打开和关闭，作为设定的操作极限位置和完全关闭位置之间或设定的操作极限位置和完全打开之间的预定范围位置。操作元件操作控制单元，使得屏蔽体打开和关闭的范围被设定在预定范围。

8. 发明授权

US4985246A Composition of feedstuff 失效
标题翻译：饲料组成
公开(公告)号：US4985246A
公开(公告)日：1991-01-15
申请号：US924763
申请日：1986-10-30
申请人： Shigeo Okonogi , Mamoru Tomita , Seiichi Shimamura , Toshio Tomimura , Norio Ishibashi , Hiroshi Miyakawa , Koichi Sugawara
发明人： Shigeo Okonogi , Mamoru Tomita , Seiichi Shimamura , Toshio Tomimura , Norio Ishibashi , Hiroshi Miyakawa , Koichi Sugawara
IPC分类号： A23K1/16 , A23K1/00 , A61K35/74
CPC分类号： A23K10/10
摘要： A composition of feedstuff containing at least 0.5 wt. %, in solid content, of residual liquid of incubated culture broth of Bifido-bacteria and/or lactic acid bacteria which residual liquid is obtainable as the waste by-product of mass production of living or viable cell mass of the microorganisms by substantially excluding microbial cell mass from the incubated culture broth thereof.
摘要翻译：饲料的组合物含有至少0.5wt。％的固体含量的双歧杆菌和/或乳酸菌的培养培养液的残留液体，残留的液体作为大量生产微生物的活细胞或活细胞块的废弃副产物，通过基本排除微生物来自其培养的培养液的细胞质量。

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