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    • 9. 发明授权
    • Closed loop cardiac resynchronization therapy using cardiac activation sequence information
    • 闭环心脏再同步治疗使用心脏激活序列信息
    • US07917215B2
    • 2011-03-29
    • US12276070
    • 2008-11-21
    • Yi ZhangYinghong YuAaron McCabeJiang DingJeffrey E. StahmannCarlos A. RicciScott A. Meyer
    • Yi ZhangYinghong YuAaron McCabeJiang DingJeffrey E. StahmannCarlos A. RicciScott A. Meyer
    • A61N1/00
    • A61N1/3712A61N1/3627A61N1/365G06F19/00
    • Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.
    • 提供一种或多种监测,诊断,除颤和起搏的心脏监测和/或刺激方法和系统。 心脏信号分离用于使用心脏激活序列信息来检测,监测,跟踪和/或趋势闭环心脏再同步治疗。 设备和方法包括使用多个电极感测多个复合心脏信号,所述电极被配置用于植入患者体内。 使用所感测的多个复合心脏信号进行源分离,产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。 使用一个或多个心脏信号向量和与一个或多个心脏信号载体相关联的信号中的一个或两个来调整心脏再同步治疗。 在另外的实施方案中,心脏再同步治疗可以被启动,终止,或者可以改变再同步治疗的一个或多个参数。
    • 10. 发明授权
    • Closed loop cardiac resynchronization therapy using cardiac activation sequence information
    • 闭环心脏再同步治疗使用心脏激活序列信息
    • US07457664B2
    • 2008-11-25
    • US11125068
    • 2005-05-09
    • Yi ZhangYinghong YuAaron R. McCabeJiang DingJeffrey E. StahmannCarlos Alberto RicciScott A. Meyer
    • Yi ZhangYinghong YuAaron R. McCabeJiang DingJeffrey E. StahmannCarlos Alberto RicciScott A. Meyer
    • A61N1/365
    • A61N1/3712A61N1/3627A61N1/365G06F19/00
    • Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track, and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.
    • 提供一种或多种监测,诊断,除颤和起搏的心脏监测和/或刺激方法和系统。 心脏信号分离用于使用心脏激活序列信息来检测,监测,跟踪和/或趋向闭环心脏再同步治疗。 设备和方法包括使用多个电极感测多个复合心脏信号,所述电极被配置用于植入患者体内。 使用所感测的多个复合心脏信号进行源分离,产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。 使用一个或多个心脏信号向量和与一个或多个心脏信号载体相关联的信号中的一个或两个来调整心脏再同步治疗。 在另外的实施方案中,心脏再同步治疗可以被启动,终止,或者可以改变再同步治疗的一个或多个参数。