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1. 发明申请

US20050118203A1 Mixing powder of plant sterol and emulsifier, and method for preparing the same 审中-公开
标题翻译：植物甾醇和乳化剂的混合粉末及其制备方法
公开(公告)号：US20050118203A1
公开(公告)日：2005-06-02
申请号：US10508690
申请日：2002-03-20
申请人： Won-Tae Yoon , Kab-Sig Kim , Tae-Jin Kim , Hyung-Pyo Hong
发明人： Won-Tae Yoon , Kab-Sig Kim , Tae-Jin Kim , Hyung-Pyo Hong
IPC分类号： A23L1/29 , A23L1/30 , A61K31/56 , A61K9/00
CPC分类号： A61K31/56 , A23L29/10 , A23L33/11 , A23V2002/00 , A23V2200/222 , A23V2250/2136
摘要： Disclosed are a mixing powder of plant sterol and emulsifier, and method for preparing the same. More particularly, the present invention provides a mixing powder of plant sterol and emulsifier for application to almost all food, irrespective of food base, to obtain an improvement in the dispersion stability of the plant sterol micelles inhibiting the absorption of cholesterol.
摘要翻译：公开了植物甾醇和乳化剂的混合粉末及其制备方法。更具体地说，本发明提供了植物甾醇和乳化剂的混合粉末，用于几乎所有的食物，不论其食物基础如何，以获得抑制胆固醇吸收的植物甾醇胶束的分散稳定性的改善。

2. 发明授权

US07994157B2 Method for dispersing plant sterol for beverage and a plant sterol-dispersed beverage, of which particle size is nanometer-scale in dispersed beverage 失效
标题翻译：分散饮料用植物甾醇和分散饮料中粒径为纳米级的植物甾醇分散饮料的方法
公开(公告)号：US07994157B2
公开(公告)日：2011-08-09
申请号：US10398001
申请日：2001-09-28
申请人： Won-Tae Yoon , Kab-Sig Kim , Bo-Chun Kim , Jung-Hee Han , Hyung-Pyo Hong
发明人： Won-Tae Yoon , Kab-Sig Kim , Bo-Chun Kim , Jung-Hee Han , Hyung-Pyo Hong
IPC分类号： A61K31/56 , A61K31/23 , A61K31/70 , A23L2/02 , A23L2/38
CPC分类号： A23L2/52 , A23C9/152 , A23L33/11 , Y10S514/951
摘要： Disclosed are a method for dispersing plant sterol for beverage and a plant sterol-dispersed beverage, of which particle size is nanometer-scale in dispersed beverage. The dispersion of plant sterols starts with the admixing of plant sterol to at least one emulsifier selected from the group consisting of sucrose fatty acid ester, sorbitan fatty acid ester and polyglycerine fatty acid ester, followed by melting the admixture by heating at 60 to 200° C. Afterwards, the molten substance is mixed with an aqueous beverage alone or an emulsifier-containing aqueous beverage in state of its own molten type or power type. This resulting mixture is stirred at a high speed to give a dispersion of plant sterols in an aqueous beverage. The beverage is superior in bioavailability, having good mouth feel, transparent aspect and no influence on the characteristic taste, flavor and color of the beverages.
摘要翻译：公开了分散饮料用植物性甾醇和分散饮料中粒径为纳米级的植物甾醇分散饮料的方法。植物甾醇的分散体从植物甾醇与至少一种选自蔗糖脂肪酸酯，脱水山梨糖醇脂肪酸酯和聚甘油脂肪酸酯的乳化剂混合开始，然后通过在60〜200℃加热熔融混合物 C.然后，将熔融物与单独的含水饮料或含乳化剂的含水饮料以其自身的熔融型或动力型混合。将所得混合物高速搅拌，得到植物甾醇在含水饮料中的分散体。该饮料具有优越的生物利用度，具有良好的口感，透明的方面，并且不影响饮料的特征味道，风味和颜色。

3. 发明申请

US20050170064A1 Plant sterol-containing food, and method for preparing the same 审中-公开
标题翻译：植物固醇食品及其制备方法
公开(公告)号：US20050170064A1
公开(公告)日：2005-08-04
申请号：US10508689
申请日：2002-03-20
申请人： Won-Tae Yoon , Kab-Sig Kim , Bo-Chun Kim , Jung-Hee Han
发明人： Won-Tae Yoon , Kab-Sig Kim , Bo-Chun Kim , Jung-Hee Han
IPC分类号： A23C9/13 , A23L1/03 , A23L1/168 , A23L1/24 , A23L1/29 , A23L1/30 , A23D7/06 , A61K31/56
CPC分类号： A61K31/56 , A23C9/13 , A23L7/148 , A23L27/60 , A23L29/10 , A23L33/11 , A23V2002/00 , A23V2200/222 , A23V2250/2136
摘要： Disclosed are the plant sterol-containing food, and methods for preparing the same. The particle size of the plant sterol contained in the food is nanometer-scale, and the plant sterol-containing food of the present invention inhibits the absorption of cholesterol.
摘要翻译：公开了含植物甾醇的食品及其制备方法。食品中含有的植物甾醇的粒径是纳米级的，本发明的含植物固醇的食物抑制胆固醇的吸收。

4. 发明授权

US07259005B2 Microorganism having ability to convert sterol into androst-4-ene-3, 17-dione/androsta-1,4-diene-3, 17-dione and preparation method and use thereof 失效
标题翻译：具有将甾醇转化成雄甾-4-烯-3,17-二酮/雄甾-1,4-二烯-3,17-二酮的能力的微生物及其制备方法和用途
公开(公告)号：US07259005B2
公开(公告)日：2007-08-21
申请号：US10477447
申请日：2002-05-10
申请人： Seung-Kwon Noh , Myung-Kuk Kim , Won-Tae Yoon , Kyung-Moon Park , Sang-Ok Park
发明人： Seung-Kwon Noh , Myung-Kuk Kim , Won-Tae Yoon , Kyung-Moon Park , Sang-Ok Park
IPC分类号： C12P33/00 , C12P33/20 , C12P33/16 , C12N1/20
CPC分类号： C12P33/00 , C12N1/20
摘要： Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly, a mutant strain of Mycobacterium fortuitum ATCC 29472, Mycobacterium fortuitum EUG-119, a method for preparation of the mutant and use thereof in preparing AD and ADD. The mutant of the present invention has an excellent ability to convent sterol into AD and ADD which are steroid hormone precursors, compared with the known microorganisms and accordingly, is very useful for mass production of steroid hormones.
摘要翻译：公开了具有优异的将甾醇转化成罗登-4-烯-3,17-二酮（AD）和雄甾-1,4-二烯-3,17-二酮（ADD）的微生物，其制备方法微生物及其用途，更具体地，是偶发分枝杆菌ATCC 29472，偶发分枝杆菌EUG-119的突变菌株，制备突变体的方法及其在制备AD和ADD中的用途。与已知的微生物相比，本发明的突变体具有优异的修饰甾体成为类固醇激素前体的AD和ADD的能力，因此对于大量生产类固醇激素非常有用。

5. 发明授权

US07241589B2 Method for preparation of androst-4-ene-3,17-dione and androsta-1,4-diene-3,17-dione 失效
标题翻译：雄甾-4-烯-3,17-二酮和雄甾-1,4-二烯-3,17-二酮的制备方法
公开(公告)号：US07241589B2
公开(公告)日：2007-07-10
申请号：US10477448
申请日：2002-05-10
申请人： Seung-Kwon Noh , Myung-Kuk Kim , Won-Tae Yoon , Kyung-Moon Park , Sang-Ok Park
发明人： Seung-Kwon Noh , Myung-Kuk Kim , Won-Tae Yoon , Kyung-Moon Park , Sang-Ok Park
IPC分类号： C12P33/00
CPC分类号： C12P33/16
摘要： The present invention relates to a method for preparation of androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). More particularly, the present invention relates to a method for preparing AD/ADD, comprising the steps of: (a) heating sterols and emulsifier respectively, to dissolve completely and mixing to prepare a mixture; (b) placing the mixture in a water bath at 70˜90° C. and stirring to obtain emulsified sterols; and (c) adding the emulsified sterols to culture media of microorganism as a component. And the present invention relates to a method for preparing AD/ADD, comprising the addition of cyclodextrin-sterol complexes extracted from milk to culture media of microorganism as a component. The emulsified sterols and cyclodextrin-sterol complexes adopted in the present invention can be easily prepared and be effectively used for obtaining AD/ADD at a high yield.
摘要翻译：雄甾-4-烯-3,17-二酮（AD）和雄甾-1,4-二烯-3,17-二酮（ADD）的制备方法技术领域本发明涉及雄甾-4-烯-3,17-二酮（AD）和雄甾-1,4-二烯-3,17-二酮（ADD）的制备方法。更具体地说，本发明涉及一种制备AD / ADD的方法，包括以下步骤：（a）分别加热固醇和乳化剂以完全溶解并混合以制备混合物; （b）将混合物置于70〜90℃的水浴中并搅拌，得到乳化甾醇; 和（c）将乳化的甾醇加入作为组分的微生物培养基中。本发明涉及AD / ADD的制备方法，其特征在于，将从乳中提取的环糊精 - 甾醇配合物添加到微生物的培养基中作为成分。本发明中采用的乳化甾醇和环糊精 - 固醇配合物可以容易地制备并且有效地用于以高产率获得AD / ADD。

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