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1. 发明授权

US07932098B2 Microfluidic system utilizing thin-film layers to route fluid 有权
标题翻译：微流体系统利用薄膜层来引导流体
公开(公告)号：US07932098B2
公开(公告)日：2011-04-26
申请号：US10286314
申请日：2002-10-31
申请人： Winthrop D. Childers , Paul Crivelli , David Tyvoll , James A. Feinn , Douglas A. Sexton
发明人： Winthrop D. Childers , Paul Crivelli , David Tyvoll , James A. Feinn , Douglas A. Sexton
IPC分类号： G01N27/26 , G01N1/10
CPC分类号： B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L2200/10 , B01L2200/12 , B01L2200/14 , B01L2300/02 , B01L2300/0645 , B01L2300/0887 , B01L2300/1827 , B01L2400/0415 , G01N1/28 , Y10T436/25 , Y10T436/25125 , Y10T436/2525 , Y10T436/25375 , Y10T436/255 , Y10T436/25625 , Y10T436/2575 , Y10T436/25875
摘要： Systems, including apparatus and methods, for microfluidic processing and/or analysis of samples. The systems include a microfluidic device having a substrate and a thin-film layer formed on the substrate. The thin-film layer may be included in electronics formed on the substrate. The electronics may provide electronic devices configured to sense or modify a property of the sample. The thin-film layer defines an opening for routing movement of fluid and/or sample within the device.
摘要翻译：用于微流体处理和/或样品分析的系统，包括装置和方法。该系统包括具有衬底和形成在衬底上的薄膜层的微流体器件。薄膜层可以包含在基板上形成的电子元件中。电子设备可以提供被配置为感测或修改样品的性质的电子设备。薄膜层限定用于在装置内引导流体和/或样品的运动的开口。

2. 发明授权

US07741123B2 Microfluidic device with thin-film electronic devices 失效
标题翻译：具有薄膜电子器件的微流控器件
公开(公告)号：US07741123B2
公开(公告)日：2010-06-22
申请号：US12069628
申请日：2008-02-11
申请人： Grant Pease , Adam L Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
发明人： Grant Pease , Adam L Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
IPC分类号： G01N21/75 , B01J14/00
CPC分类号： B01L7/525 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2200/147 , B01L2300/024 , B01L2300/0816 , B01L2300/0874 , B01L2300/1827 , B01L2300/1883 , B01L2400/0415 , Y10T436/11 , Y10T436/2575
摘要： A microfluidic device for analysis of a sample. The microfluidic device includes a substrate portion that at least partially defines a chamber for receiving the sample. The substrate portion includes a substrate having a surface. The substrate portion also includes a plurality of thin-film layers formed on the substrate adjacent the surface. The thin-film layers form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers.
摘要翻译：用于分析样品的微流体装置。微流体装置包括至少部分地限定用于接收样品的室的基底部分。基板部分包括具有表面的基板。衬底部分还包括在邻近表面的衬底上形成的多个薄膜层。薄膜层形成多个电子装置。至少两个电子设备中的每一个由不同的薄膜层组形成。

3. 发明申请

US20080164155A1 Microfluidic device with thin-film electronic devices 失效
标题翻译：具有薄膜电子器件的微流控器件
公开(公告)号：US20080164155A1
公开(公告)日：2008-07-10
申请号：US12069628
申请日：2008-02-11
申请人： Grant Pease , Adam L. Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
发明人： Grant Pease , Adam L. Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
IPC分类号： G01N27/26
CPC分类号： B01L7/525 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2200/147 , B01L2300/024 , B01L2300/0816 , B01L2300/0874 , B01L2300/1827 , B01L2300/1883 , B01L2400/0415 , Y10T436/11 , Y10T436/2575
摘要： A microfluidic device for analysis of a sample. The microfluidic device includes a substrate portion that at least partially defines a chamber for receiving the sample. The substrate portion includes a substrate having a surface. The substrate portion also includes a plurality of thin-film layers formed on the substrate adjacent the surface. The thin-film layers form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers.
摘要翻译：用于分析样品的微流体装置。微流体装置包括至少部分地限定用于接收样品的室的基底部分。基板部分包括具有表面的基板。衬底部分还包括在邻近表面的衬底上形成的多个薄膜层。薄膜层形成多个电子装置。至少两个电子设备中的每一个由不同的薄膜层组形成。

4. 发明授权

US07338637B2 Microfluidic device with thin-film electronic devices 有权
标题翻译：具有薄膜电子器件的微流控器件
公开(公告)号：US07338637B2
公开(公告)日：2008-03-04
申请号：US10355397
申请日：2003-01-31
申请人： Grant Pease , Adam L Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
发明人： Grant Pease , Adam L Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
IPC分类号： B01L3/02 , B32B5/02 , B32B27/04 , B32B27/12 , G01N15/06
CPC分类号： B01L7/525 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2200/147 , B01L2300/024 , B01L2300/0816 , B01L2300/0874 , B01L2300/1827 , B01L2300/1883 , B01L2400/0415 , Y10T436/11 , Y10T436/2575
摘要： A microfluidic device for analysis of a sample. The microfluidic device includes a substrate portion that at least partially defines a chamber for receiving the sample. The substrate portion includes a substrate having a surface. The substrate portion also includes a plurality of thin-film layers formed on the substrate adjacent the surface. The thin-film layers form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers. The at least two electronic devices may include 1) a temperature control device for controlling the temperature of fluid in the chamber, and 2) an other electronic device configured to sense or modify a property of fluid in the chamber.
摘要翻译：用于分析样品的微流体装置。微流体装置包括至少部分地限定用于接收样品的室的基底部分。基板部分包括具有表面的基板。衬底部分还包括在邻近表面的衬底上形成的多个薄膜层。薄膜层形成多个电子装置。至少两个电子设备中的每一个由不同的薄膜层组形成。所述至少两个电子设备可以包括：1）用于控制所述腔室中的流体的温度的温度控制装置，以及2）构造成感测或改变所述腔室中的流体性质的另一电子装置。

5. 发明授权

US07389879B2 Sorting particles 有权
标题翻译：排序粒子
公开(公告)号：US07389879B2
公开(公告)日：2008-06-24
申请号：US10763112
申请日：2004-01-21
申请人： David Tyvoll , Winthrop D. Childers , Paul Crivelli
发明人： David Tyvoll , Winthrop D. Childers , Paul Crivelli
IPC分类号： B07C5/02
CPC分类号： G01N15/1459 , G01N15/1056 , G01N2015/1081 , G01N2015/149 , Y10S209/906
摘要： A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.
摘要翻译：用于分选颗粒的装置。该装置可以包括限定具有入口和第一和第二出口的通道的通道结构。该装置还可以包括第一和第二传送机构。第一输送机构可以被配置成产生第一颗粒和一个或多个第二颗粒的颗粒物流。每个颗粒可以沿着通道从入口移动到第一出口，并且可以设置在由通道结构支撑的流体中。第二传送机构可以被配置为被脉冲激活以选择性地将颗粒流中的至少一个第二颗粒移动到第二出口。

6. 发明授权

US07497334B2 Sorting particles 有权
标题翻译：排序粒子
公开(公告)号：US07497334B2
公开(公告)日：2009-03-03
申请号：US11999943
申请日：2007-12-07
申请人： David Tyvoll , Winthrop D. Childers , Paul Crivelli
发明人： David Tyvoll , Winthrop D. Childers , Paul Crivelli
IPC分类号： B07C5/02
CPC分类号： G01N15/1459 , G01N15/1056 , G01N2015/1081 , G01N2015/149 , Y10S209/906
摘要： A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.
摘要翻译：用于分选颗粒的装置。该装置可以包括限定具有入口和第一和第二出口的通道的通道结构。该装置还可以包括第一和第二传送机构。第一输送机构可以被配置成产生第一颗粒和一个或多个第二颗粒的颗粒物流。每个颗粒可以沿着通道从入口移动到第一出口，并且可以设置在由通道结构支撑的流体中。第二传送机构可以被配置为被脉冲激活以选择性地将颗粒流中的至少一个第二颗粒移动到第二出口。

7. 发明申请

US20080087585A1 Sorting particles 有权
公开(公告)号：US20080087585A1
公开(公告)日：2008-04-17
申请号：US11999943
申请日：2007-12-07
申请人： David Tyvoll , Winthrop Childers , Paul Crivelli
发明人： David Tyvoll , Winthrop Childers , Paul Crivelli
IPC分类号： B07C9/00
CPC分类号： G01N15/1459 , G01N15/1056 , G01N2015/1081 , G01N2015/149 , Y10S209/906
摘要： A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.

8. 发明申请

US20050173313A1 Sorting particles 有权
标题翻译：排序粒子
公开(公告)号：US20050173313A1
公开(公告)日：2005-08-11
申请号：US10763112
申请日：2004-01-21
申请人： David Tyvoll , Winthrop Childers , Paul Crivelli
发明人： David Tyvoll , Winthrop Childers , Paul Crivelli
IPC分类号： G01N33/48 , B03B13/00 , B03B13/04 , B07C99/00 , G01N15/00 , G01N15/10 , G01N15/14 , B03D1/00 , B03B5/60 , B03B5/64
CPC分类号： G01N15/1459 , G01N15/1056 , G01N2015/1081 , G01N2015/149 , Y10S209/906
摘要： A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.
摘要翻译：用于分选颗粒的装置。该装置可以包括限定具有入口和第一和第二出口的通道的通道结构。该装置还可以包括第一和第二传送机构。第一输送机构可以被配置成产生第一颗粒和一个或多个第二颗粒的颗粒物流。每个颗粒可以沿着通道从入口移动到第一出口，并且可以设置在由通道结构支撑的流体中。第二传送机构可以被配置为被脉冲激活以选择性地将颗粒流中的至少一个第二颗粒移动到第二出口。

9. 发明申请

US20050178700A1 Sorting particles in parallel 审中-公开
标题翻译：并行排序粒子
公开(公告)号：US20050178700A1
公开(公告)日：2005-08-18
申请号：US10762688
申请日：2004-01-21
申请人： David Tyvoll , Winthrop Childers , Paul Crivelli
发明人： David Tyvoll , Winthrop Childers , Paul Crivelli
IPC分类号： G01N15/00 , B03C5/02 , B07C5/34 , B07C5/38 , C12M1/00 , C12M1/26 , C12M1/34 , G01N1/02 , G01N15/14 , G01N35/02 , G01N35/08 , G01N37/00
CPC分类号： G01N15/14 , B03C5/026 , B03C5/028 , G01N2015/149
摘要： A device for sorting particles in parallel. The device may include an input reservoir configured to hold a mixture of first particles and one or more second particles. The device also may include a transport mechanism configured to move portions of the mixture in parallel from the input reservoir. The device may further include a plurality of sorter units in fluid communication with the input reservoir. The plurality of sorter units may be configured to receive the portions of the mixture. In addition, each sorter unit may be configured to selectively move at least one second particle, if received in one of the portions, from a path followed by first particles received in the one portion so that the at least second particle follows a different path.
摘要翻译：用于并行排列颗粒的装置。装置可以包括配置成保持第一颗粒和一个或多个第二颗粒的混合物的输入储存器。该装置还可以包括传送机构，该传送机构被配置为使得混合物的部分从输入储存器平行移动。该装置还可以包括与输入储存器流体连通的多个分选单元。多个分选单元可以被配置为接收混合物的部分。另外，每个分拣机单元可以被配置成选择性地移动至少一个第二粒子，如果从其中一个部分中接收到的，则在一个部分中接收的第一粒子之后的路径，使得至少第二粒子遵循不同的路径。

10. 外观设计

USD640389S1 Test strip 有权
标题翻译：测试条
公开(公告)号：USD640389S1
公开(公告)日：2011-06-21
申请号：US29363033
申请日：2010-06-03
申请人： Karl Francis , Paul Crivelli , Emily Parker
设计人： Karl Francis , Paul Crivelli , Emily Parker

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