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1. 发明授权

US06212063B1 Implantable medical device having flat electrolytic capacitor with connector block and sealed feedthroughs 失效
标题翻译：具有扁平电解电容器的可插入式医疗设备，具有连接器块和密封馈通
公开(公告)号：US06212063B1
公开(公告)日：2001-04-03
申请号：US09104104
申请日：1998-06-24
申请人： William L. Johnson , Anthony R. Rorvick , Mark D. Breyen , Paul A. Pignato , Norma K. Bullock , Joseph F. Lessar , Andrew J. Ries , Randall V. Sparer , Christopher M. Hobot , Edward Di Domenico , Steven G. Rockow
发明人： William L. Johnson , Anthony R. Rorvick , Mark D. Breyen , Paul A. Pignato , Norma K. Bullock , Joseph F. Lessar , Andrew J. Ries , Randall V. Sparer , Christopher M. Hobot , Edward Di Domenico , Steven G. Rockow
IPC分类号： H01G908
CPC分类号： A61N1/375 , A61N1/3758 , A61N1/3956
摘要： An implantable medical device such as a defibrillator is described. The device includes an hermetically sealed housing containing a flat electrolytic capacitor and an energy source such as a battery. The battery is connected to the capacitor and provides charge thereto. The capacitor stores the charge at a relatively high voltage. The charge stored in the capacitor is discharged through a defibrillation lead to a site on or in the heart when fibrillation of the heart is detected by the implantable medical device. Methods of making and using the implantable medical device, the capacitor, and their various components are disclosed.
摘要翻译：描述了诸如除颤器的可植入医疗装置。该装置包括一个包含平坦的电解电容器和诸如电池的能量源的气密密封的外壳。电池连接到电容器并提供电荷。电容器将电荷存储在较高的电压。存储在电容器中的电荷通过除颤导线排出到心脏上或心脏中的部位，通过可植入医疗装置检测心脏的颤动。公开了制造和使用可植入医疗装置，电容器及其各种部件的方法。

2. 发明授权

US06040082A Volumetrically efficient battery for implantable medical devices 失效
标题翻译：用于植入式医疗设备的体积有效的电池
公开(公告)号：US06040082A
公开(公告)日：2000-03-21
申请号：US903297
申请日：1997-07-30
申请人： David P. Haas , William G. Howard , Ann M. Crespi , Anthony R. Rorvick , Steven Rockow , Andrew J. Ries
发明人： David P. Haas , William G. Howard , Ann M. Crespi , Anthony R. Rorvick , Steven Rockow , Andrew J. Ries
IPC分类号： A61N1/378 , A61N1/39 , H01M2/02 , H01M2/04 , H01M2/10 , H01M6/10 , H01M6/16 , H01M10/04 , H01M10/05 , H01M4/02
CPC分类号： H01M2/027 , A61N1/378 , H01M10/0431 , H01M2/0232 , H01M2/0275 , H01M2/0426 , H01M2/1022 , H01M6/10 , A61N1/3956 , H01M10/05 , H01M2/0217 , H01M6/16
摘要： A high rate battery having a coiled electrode assembly housed in a case that efficiently utilizes the space available in many implantable medical devices is disclosed. The battery case provides a planar surface opposite an arcuate surface to allow for the close abutting of other components located within the implantable device while also providing for efficient location of the battery within an arcuate edge of the device. The battery cases include at least three planar sides extending between a top and a base of the battery case, wherein the arcuate side is located directly opposite one of the planar sides. The battery case may form a prismatic solid shape with one arcuate surface and five planar surfaces. The batteries may include a coiled electrode assembly including an anode and a cathode; electrolyte; and a case liner containing the electrode assembly. The coiled electrode assembly can have an elliptical cross-section including two arcuate ends, wherein one of the arcuate ends is nested within an arcuate side of the case. The batteries are capable of delivering about 20 joules or more in about 20 seconds or less; and may also be capable of delivering about 20 joules or more at least twice in a period of about 30 seconds. Also included are implantable defibrillator devices incorporating the batteries and methods of manufacturing the batteries including drawing the battery case from metal.
摘要翻译：公开了一种高速电池，其具有容纳在有效利用许多可植入医疗装置中的空间的壳体中的盘绕电极组件。电池壳提供与弓形表面相对的平坦表面，以允许位于可植入装置内的其它部件的紧密邻接，同时还提供电池在装置的弓形边缘内的有效定位。电池壳体包括在电池壳体的顶部和底部之间延伸的至少三个平面侧，其中弧形侧面位于与一个平面侧面正对的位置。电池盒可以形成具有一个弧形表面和五个平坦表面的棱柱形实体形状。电池可以包括包括阳极和阴极的线圈电极组件; 电解液以及包含电极组件的壳体衬里。线圈电极组件可以具有包括两个弓形端部的椭圆形横截面，其中弓形端部之一嵌套在壳体的弧形侧内。电池能够在约20秒以内提供约20焦耳或更多; 并且还可以在约30秒的时间内能够输送约20焦耳或更多至少两次。还包括结合有电池的可植入除颤器装置和制造电池的方法，包括从金属中拉出电池壳体。

3. 发明授权

US06799072B2 Electrically insulated component sub-assemblies of implantable medical devices 失效
标题翻译：可植入医疗器械的电绝缘组件子组件
公开(公告)号：US06799072B2
公开(公告)日：2004-09-28
申请号：US10132781
申请日：2002-04-25
申请人： Andrew J. Ries , Mark D. Breyen , John D. Norton , Thomas P. Miltich , Steven J. May , Angela Rodgers
发明人： Andrew J. Ries , Mark D. Breyen , John D. Norton , Thomas P. Miltich , Steven J. May , Angela Rodgers
IPC分类号： A61N1372
CPC分类号： A61N1/375 , A61N1/3758 , B33Y80/00
摘要： Implantable medical devices (IMDs) and their various components, particularly methods and apparatus for electrically isolating and supporting components of an IMD IPG, e.g., capacitors of a capacitor sub-assembly, thereof in volumetrically efficient ways. A capacitor sub-assembly comprising two or more capacitors stacked side-by-side such that the facing capacitor case major sides are separated by a reliable and simple to apply insulation layer of minimal thickness is disclosed for assembly with other components of an ICD IPG into an IPG housing. A shape conforming insulating spacer is formed of an insulating polymer to conform to the shape of a first capacitor case major side and the perimeter of that major side. The shape conforming insulating spacer is simply applied or adhered by adhesive layers, bands or patterns to one or both of the facing capacitor case major sides.
摘要翻译：可植入医疗器械（IMD）及其各种部件，特别是用于以体积有效的方式电气隔离和支撑IMD IPG的部件（例如电容器子组件的电容器）的方法和装置。电容器子组件包括并排堆叠的两个或更多个电容器，使得面对的电容器壳体主侧面被可靠且简单地施加最小厚度的绝缘层分开，用于与ICD IPG的其它部件组装成 IPG住房。形状合适的绝缘隔离物由绝缘聚合物形成，以符合第一电容器壳体主侧和该主要侧面的周边的形状。形状一致的绝缘间隔物通过粘合剂层，带或图案简单地施加或粘附到面向电容器壳体主侧中的一个或两个。

4. 发明授权

US08249710B2 Complex connector in component footprint of implantable medical device 有权
标题翻译：可植入医疗器械部件占地面积的复杂连接器
公开(公告)号：US08249710B2
公开(公告)日：2012-08-21
申请号：US10266651
申请日：2002-10-07
申请人： Angela Rodgers , Andrew J. Ries , Kurt J. Casby , John D. Norton , Mark D. Breyen , Dan D. Erklouts , Brian J. Ross , Timothy T. Bomstad , Wayne L. Appleseth , Michael E. Clarke , Jeffrey L. Kehn , Scott J. Robinson
发明人： Angela Rodgers , Andrew J. Ries , Kurt J. Casby , John D. Norton , Mark D. Breyen , Dan D. Erklouts , Brian J. Ross , Timothy T. Bomstad , Wayne L. Appleseth , Michael E. Clarke , Jeffrey L. Kehn , Scott J. Robinson
IPC分类号： A61N1/375 , H05K5/06
CPC分类号： A61N1/05 , A61N1/375 , H01G9/008 , H01G9/08 , H01R2201/12
摘要： At least one storage component, for example a capacitor or a battery, of an implantable medical device includes two perimeter surfaces. Linear extensions of the two perimeter surfaces define a zone. An electrical connector, which is coupled to the storage component and includes at least one connection point for electrically connecting the storage component with at least one other component within the medical device, is contained within the zone defined by the linear extensions of the two perimeter surfaces.
摘要翻译：可植入医疗装置的至少一个存储部件，例如电容器或电池包括两个周边表面。两个周边表面的线性延伸部分定义一个区域。耦合到存储部件并且包括用于将存储部件与医疗装置内的至少一个其它部件电连接的至少一个连接点的电连接器包含在由两个周边表面的线性延伸部限定的区域内。

5. 发明授权

US08386044B2 Complex connector in component footprint of implantable medical device 有权
标题翻译：可植入医疗器械部件占地面积的复杂连接器
公开(公告)号：US08386044B2
公开(公告)日：2013-02-26
申请号：US11290282
申请日：2005-11-30
申请人： Angela Rodgers , Andrew J. Ries , Kurt J. Casby , John D. Norton , Mark D. Breyen , Dan D. Erklouts , Brian J. Ross , Timothy T. Bomstad , Wayne L. Appleseth , Michael E. Clarke , Jeffrey L. Kehn , Scott J. Robinson
发明人： Angela Rodgers , Andrew J. Ries , Kurt J. Casby , John D. Norton , Mark D. Breyen , Dan D. Erklouts , Brian J. Ross , Timothy T. Bomstad , Wayne L. Appleseth , Michael E. Clarke , Jeffrey L. Kehn , Scott J. Robinson
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/375 , H01G9/008 , H01G9/08 , H01R2201/12
摘要： A complex connector and component within an implantable medical device in which the complex connector is positioned within the spacing footprint of the component to optimize packaging within the device.
摘要翻译：可植入医疗装置内的复杂连接器和部件，其中复合连接器位于部件的间隔覆盖区内，以优化装置内的包装。

6. 发明授权

US08290593B2 Implantable medical device including a plurality of lead connection assemblies 有权
标题翻译：可植入医疗装置，包括多个引线连接组件
公开(公告)号：US08290593B2
公开(公告)日：2012-10-16
申请号：US12610157
申请日：2009-10-30
申请人： Robert W. Libbey , William T. Donofrio , John E. Burnes , Paul G. Krause , Michael K. Berquist , Olivier Blandin , Michael Hudziak , William L. Johnson , John E. Nicholson , George Patras , Andrew J. Ries , Jeffrey Swanson , Paul Vahle , Thomas J. Olson , William K. Wenger , Michael R. Klardie , Samira Tahvildari
发明人： Robert W. Libbey , William T. Donofrio , John E. Burnes , Paul G. Krause , Michael K. Berquist , Olivier Blandin , Michael Hudziak , William L. Johnson , John E. Nicholson , George Patras , Andrew J. Ries , Jeffrey Swanson , Paul Vahle , Thomas J. Olson , William K. Wenger , Michael R. Klardie , Samira Tahvildari
IPC分类号： A61N1/375
CPC分类号： A61N1/3752
摘要： An implantable medical device (IMD) may include at least two separate lead connection assemblies, each with electrical connectors for connecting implantable leads to the IMD. In some examples, a IMD may include a first therapy module configured to generate a first electrical stimulation therapy and a second therapy module configured to generate a second electrical stimulation therapy for delivery to the patient. The IMD may include a first lead connection assembly including a first electrical connector electrically coupled to the first therapy module and a second lead connection assembly including a second electrical connector electrically coupled to the second therapy module. In some examples, the first and second lead connection assemblies are distributed around the outer perimeter of the IMD housing.
摘要翻译：可植入医疗装置（IMD）可以包括至少两个单独的引线连接组件，每个具有用于将可植入引线连接到IMD的电连接器。在一些示例中，IMD可以包括被配置为产生第一电刺激治疗的第一治疗模块和被配置为产生用于递送给患者的第二电刺激治疗的第二治疗模块。 IMD可以包括第一引线连接组件，其包括电耦合到第一治疗模块的第一电连接器和包括电耦合到第二治疗模块的第二电连接器的第二引线连接组件。在一些示例中，第一和第二引线连接组件围绕IMD外壳的外周分布。

7. 发明申请

US20100137929A1 IMPLANTABLE MEDICAL DEVICE INCLUDING A PLURALITY OF LEAD CONNECTION ASSEMBLIES 有权
标题翻译：可塑性医疗设备，包括多个铅连接组件
公开(公告)号：US20100137929A1
公开(公告)日：2010-06-03
申请号：US12610157
申请日：2009-10-30
申请人： Robert W. Libbey , William T. Donofrio , John E. Burnes , Paul G. Krause , Michael K. Berquist , Olivier Blandin , Michael Hudziak , William L. Johnson , John E. Nicholson , George Patras , Andrew J. Ries , Jeffrey Swanson , Paul Vahle , Thomas J. Olson , William K. Wenger , Michael R. Klardie , Samira Tahvildari
发明人： Robert W. Libbey , William T. Donofrio , John E. Burnes , Paul G. Krause , Michael K. Berquist , Olivier Blandin , Michael Hudziak , William L. Johnson , John E. Nicholson , George Patras , Andrew J. Ries , Jeffrey Swanson , Paul Vahle , Thomas J. Olson , William K. Wenger , Michael R. Klardie , Samira Tahvildari
IPC分类号： A61N1/375
CPC分类号： A61N1/3752
摘要： An implantable medical device (IMD) may include at least two separate lead connection assemblies, each with electrical connectors for connecting implantable leads to the IMD. In some examples, a IMD may include a first therapy module configured to generate a first electrical stimulation therapy and a second therapy module configured to generate a second electrical stimulation therapy for delivery to the patient. The IMD may include a first lead connection assembly including a first electrical connector electrically coupled to the first therapy module and a second lead connection assembly including a second electrical connector electrically coupled to the second therapy module. In some examples, the first and second lead connection assemblies are distributed around the outer perimeter of the IMD housing.
摘要翻译：可植入医疗装置（IMD）可以包括至少两个单独的引线连接组件，每个具有用于将可植入引线连接到IMD的电连接器。在一些示例中，IMD可以包括被配置为产生第一电刺激治疗的第一治疗模块和被配置为产生用于递送给患者的第二电刺激治疗的第二治疗模块。 IMD可以包括第一引线连接组件，其包括电耦合到第一治疗模块的第一电连接器和包括电耦合到第二治疗模块的第二电连接器的第二引线连接组件。在一些示例中，第一和第二引线连接组件围绕IMD外壳的外周分布。

8. 发明授权

US09242108B2 Medical device surface electrode 有权
标题翻译：医疗器械表面电极
公开(公告)号：US09242108B2
公开(公告)日：2016-01-26
申请号：US12847743
申请日：2010-07-30
申请人： Eric John Wengreen , Andrew J. Ries , David J. Saltzman , Randy S. Roles , Scott J. Robinson , David B. Engmark , John Eric Lovins
发明人： Eric John Wengreen , Andrew J. Ries , David J. Saltzman , Randy S. Roles , Scott J. Robinson , David B. Engmark , John Eric Lovins
IPC分类号： A61N1/375
CPC分类号： A61N1/3754 , A61N1/3756
摘要： Structures and methods relating to electrodes for incorporation into a feedthrough with a profile adapted for subcutaneous sensing of physiologic and cardiac signals. Electrode assemblies are adapted for integration with feedthroughs and provide reliable insulation from the implantable medical device housing. Various structures and manufacturing processes are implemented to provide a large sensing surface with a low profile. The subcutaneous sensing electrode assembly can provide a leadless sensing system and further enhances installation and follow-up procedures.
摘要翻译：与用于结合到馈通中的电极相关的结构和方法，其具有适于皮下感测生理和心脏信号的轮廓。电极组件适于与馈通集成并且提供与可植入医疗装置壳体的可靠绝缘。实现各种结构和制造工艺以提供具有低轮廓的大的感测表面。皮下感测电极组件可以提供无引线感测系统，并进一步增强安装和后续程序。

9. 发明授权

US08945451B2 Implantable medical electrical device connector module assemblies and methods 有权
标题翻译：植入式医疗电气设备连接器模块组件及方法
公开(公告)号：US08945451B2
公开(公告)日：2015-02-03
申请号：US13473965
申请日：2012-05-17
申请人： Andrew J. Ries , Jeevan M. Prasannakumar , Richard P. Nelson
发明人： Andrew J. Ries , Jeevan M. Prasannakumar , Richard P. Nelson
IPC分类号： B29C45/14
CPC分类号： B29C45/1671 , A61N1/3754 , B29C45/14065 , B29C45/14639 , B29L2031/753
摘要： Methods for forming an insulative body of an implantable medical device connector module assembly employ an injection molding process, whereby first and second shots of insulative material form core and an overlay portions, respectively. In some methods, a panel portion of an electrical component is mounted between opposing surfaces of a mold such that a finger-like portion of the component extends into a cavity of the mold, with a first side thereof touching another surface of the mold and a second, opposite side exposed within the cavity; following first shot injection, the core portion captures the finger-like portion in relatively rigid relation thereto. When two types of connector bores are formed, a color indicator may be engaged with a feature of the core portion that is located in proximity to a connector bore of the first type, and then the overlay portion is formed over the indicator.
摘要翻译：用于形成可植入医疗器械连接器模块组件的绝缘体的方法采用注射成型工艺，其中第一和第二隔离材料分别形成芯部和覆盖部分。在一些方法中，电气部件的面板部分安装在模具的相对表面之间，使得部件的指状部分延伸到模具的空腔中，其第一侧接触模具的另一表面，并且第二，相对侧暴露在空腔内; 在第一次注射之后，芯部分以相对刚性的关系捕获手指状部分。当形成两种类型的连接器孔时，颜色指示器可以与位于第一类型的连接器孔附近的芯部分的特征接合，然后覆盖部分形成在指示器之上。

10. 发明授权

US08628348B2 Connector module assemblies, methods, and components for implantable medical electrical devices 有权
标题翻译：用于可植入医疗电气设备的连接器模块组件，方法和部件
公开(公告)号：US08628348B2
公开(公告)日：2014-01-14
申请号：US13473934
申请日：2012-05-17
申请人： Andrew J. Ries , Jeevan M. Prasannakumar , Richard P. Nelson
发明人： Andrew J. Ries , Jeevan M. Prasannakumar , Richard P. Nelson
IPC分类号： H01R13/405
CPC分类号： A61N1/05 , A61N1/3752 , H01Q1/273 , H01R4/023 , H01R4/34 , H01R24/58 , H01R43/24 , H01R2103/00 , H01R2201/12 , Y10T29/49174 , Y10T29/49204
摘要： A contact component of an implantable medical device connector module assembly includes a threaded bore in fluid communication with a connector bore thereof, and a flanged bore in fluid communication with the threaded bore. A perimeter surface of the flanged bore creates a shutoff with a pin during injection molding to form an insulative body of the assembly, and a perimeter surface of an insulative bore formed around the pin is preferably flush with that of the flanged bore of the contact component. A centerline axis of the flanged bore is preferably aligned with that of the threaded bore, for example, so that the molded insulative bore has a centerline axis aligned with that of the threaded bore of the contact component.
摘要翻译：可植入医疗装置连接器模块组件的接触部件包括与其连接器孔流体连通的螺纹孔和与螺纹孔流体连通的凸缘孔。凸缘孔的周边表面在注射成型期间产生与销的关闭以形成组件的绝缘体，并且围绕销的形成的绝缘孔的周边表面优选地与接触部件的凸缘孔的周边表面齐平。凸缘孔的中心轴线优选地与螺纹孔的中心线对准，例如，使得模制的绝缘孔具有与接触部件的螺纹孔的中心线对准的中心线轴线。

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