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1. 发明申请

US20140017312A1 Multi-vitamin and Mineral Nutritional Supplements 审中-公开
标题翻译：多维生素和矿物质营养补品
公开(公告)号：US20140017312A1
公开(公告)日：2014-01-16
申请号：US14031536
申请日：2013-09-19
申请人： William Bubnis , Richard Cotter , Paul W. Herman , Judith Moreines , Scott W. Poxon , Bruce W. Sutton , Jeffrey V. Vernon , Denise L. Walters , Michael G. Williams , Neil Wittenberg
发明人： William Bubnis , Richard Cotter , Paul W. Herman , Judith Moreines , Scott W. Poxon , Bruce W. Sutton , Jeffrey V. Vernon , Denise L. Walters , Michael G. Williams , Neil Wittenberg
IPC分类号： A61K33/00 , A61K31/575 , A61K31/675 , A61K9/10 , A61K31/525 , A61K31/352 , A61K31/375 , A61K9/28 , A61K9/20 , A61K31/714
CPC分类号： A61K33/00 , A23L33/105 , A23L33/11 , A23L33/15 , A23L33/16 , A23P10/20 , A23V2002/00 , A61K9/10 , A61K9/20 , A61K9/284 , A61K31/352 , A61K31/355 , A61K31/375 , A61K31/51 , A61K31/525 , A61K31/56 , A61K31/575 , A61K31/675 , A61K31/714 , A61K45/06 , A61K2300/00 , A23V2250/1592 , A23V2250/1598 , A23V2250/161 , A23V2250/1642 , A23V2250/1626 , A23V2250/1588 , A23V2250/1612 , A23V2250/1578 , A23V2250/1618 , A23V2250/1608 , A23V2250/1572 , A23V2250/1628 , A23V2250/163 , A23V2250/1636 , A23V2250/702 , A23V2250/7044 , A23V2250/708 , A23V2250/7052 , A23V2250/706 , A23V2250/7056 , A23V2250/712 , A23V2250/2136 , A23V2250/213 , A23V2200/3262 , A23V2250/71 , A23V2250/714 , A23V2250/304 , A23V2250/7046 , A23V2250/72 , A23V2250/705
摘要： The invention provides a nutritional supplement which includes micronutrients to facilitate reduction of cholesterol, and/or reduction of homocystein and/or reduction of low-density lipoprotein-cholesterol (LDL-C) oxidation in humans. In one embodiment the supplement is a multi-vitamin, a mineral supplement which includes at least one component known to reduce cholesterol. The invention further provides a method for tableting one fourth to one half of the daily effective dosage of a phytosterol containing nutritional supplement in a practical sized tablet and a method for reducing blood cholesterol in humans.
摘要翻译：本发明提供一种营养补充剂，其包括促进人体胆固醇降低和/或降低半胱氨酸和/或降低低密度脂蛋白胆固醇（LDL-C）氧化的微量营养素。在一个实施方案中，补充剂是多种维生素，矿物质补充剂，其包括已知降低胆固醇的至少一种组分。本发明还提供了将实用大小的片剂中含有植物甾醇的营养补充剂的每日有效剂量的四分之一到一半的压片和降低人体血液胆固醇的方法。

2. 发明申请

US20110223250A1 MULTI-VITAMIN AND MINERAL NUTRITIONAL SUPPLEMENTS 审中-公开
标题翻译：多维生素和矿物营养补充剂
公开(公告)号：US20110223250A1
公开(公告)日：2011-09-15
申请号：US13023671
申请日：2011-02-09
申请人： William Bubnis , Richard Cotter , Paul W. Herman , Judith Moreines , Scott W. Poxon , Bruce W. Sutton , Jeffrey V. Vernon , Denise L. Walters , Michael G. Williams , Neil Wittenberg
发明人： William Bubnis , Richard Cotter , Paul W. Herman , Judith Moreines , Scott W. Poxon , Bruce W. Sutton , Jeffrey V. Vernon , Denise L. Walters , Michael G. Williams , Neil Wittenberg
IPC分类号： A61K9/28 , A61K9/20 , A61K33/42 , A61P3/06 , A61K9/00
摘要： The invention provides a nutritional supplement which includes micronutrients to facilitate reduction of cholesterol, and/or reduction of homocystein and/or reduction of low-density lipoprotein-cholesterol (LDL-C) oxidation in humans. In one embodiment the supplement is a multi-vitamin, a mineral supplement which includes at least one component known to reduce cholesterol. The invention further provides a method for tableting one fourth to one half of the daily effective dosage of a phytosterol containing nutritional supplement in a practical sized tablet and a method for reducing blood cholesterol in humans.
摘要翻译：本发明提供一种营养补充剂，其包括促进人体胆固醇降低和/或降低半胱氨酸和/或降低低密度脂蛋白胆固醇（LDL-C）氧化的微量营养素。在一个实施方案中，补充剂是多种维生素，矿物质补充剂，其包括已知降低胆固醇的至少一种组分。本发明还提供了将实用大小的片剂中含有植物甾醇的营养补充剂的每日有效剂量的四分之一到一半的压片和降低人体血液胆固醇的方法。

3. 发明申请

US20050214383A1 Multi-vitamin and mineral nutritional supplements 审中-公开
标题翻译：多种维生素和矿物质营养补品
公开(公告)号：US20050214383A1
公开(公告)日：2005-09-29
申请号：US11090486
申请日：2005-03-28
申请人： William Bubnis , Richard Cotter , Paul Herman , Judith Moreines , Scott Poxon , Bruce Sutton , Jeffrey Vernon , Denise Walters , Michael Williams , Neil Wittenberg
发明人： William Bubnis , Richard Cotter , Paul Herman , Judith Moreines , Scott Poxon , Bruce Sutton , Jeffrey Vernon , Denise Walters , Michael Williams , Neil Wittenberg
IPC分类号： A61K31/51 , A61K31/525 , A61K31/56 , A61K31/714
摘要： The invention provides a nutritional supplement which includes micronutrients to facilitate reduction of cholesterol, and/or reduction of homocystein and/or reduction of low-density lipoprotein-cholesterol (LDL-C) oxidation in humans. In one embodiment the supplement is a multi-vitamin, a mineral supplement which includes at least one component known to reduce cholesterol. The invention further provides a method for tableting one fourth to one half of the daily effective dosage of a phytosterol containing nutritional supplement in a practical sized tablet and a method for reducing blood cholesterol in humans.
摘要翻译：本发明提供一种营养补充剂，其包括促进人体胆固醇降低和/或降低半胱氨酸和/或降低低密度脂蛋白胆固醇（LDL-C）氧化的微量营养素。在一个实施方案中，补充剂是多种维生素，矿物质补充剂，其包括已知降低胆固醇的至少一种组分。本发明还提供了将实用大小的片剂中含有植物甾醇的营养补充剂的每日有效剂量的四分之一到一半的压片和降低人体血液胆固醇的方法。

4. 发明授权

US5760020A Lipid emulsion 失效
公开(公告)号：US5760020A
公开(公告)日：1998-06-02
申请号：US726369
申请日：1996-10-04
申请人： Richard Cotter
发明人： Richard Cotter
IPC分类号： A61K9/00 , A61K31/23 , A61K35/60 , A61K31/685 , B01J13/00
CPC分类号： A61K9/0029 , A61K31/23 , A61K35/60 , Y10S514/938
摘要： A lipid emulsion is provided comprising water, an emulsifier, and a glyceride oil component. The weight ratio of the emulsifier to glyceride oil is approximately 0.04 to about 0.01. It has been found that intravenous lipid emulsions having a weight ratio of emulsifier to glyceride oil of approximately 0.04 to about 0.01 are more rapidly metabolically utilized.

5. 发明授权

US4920098A Nutritional support or therapy for individuals at risk or under treatment for atherosclerotic vascular, cardiovascular, and/or thrombotic diseases 失效
标题翻译：危险或正在治疗动脉粥样硬化血管，心血管和/或血栓性疾病的个体的营养支持或治疗
公开(公告)号：US4920098A
公开(公告)日：1990-04-24
申请号：US403849
申请日：1989-08-28
申请人： Richard Cotter , Robert C. Johnson , Michael Ward , David C. Madsen , Anthony J. Valicenti , Michael P. Menard , Hugh N. Tucker
发明人： Richard Cotter , Robert C. Johnson , Michael Ward , David C. Madsen , Anthony J. Valicenti , Michael P. Menard , Hugh N. Tucker
IPC分类号： A23L1/30 , A23L1/305 , A61K9/00
CPC分类号： A61K9/0029 , A23L33/12 , A23L33/18 , Y10S514/824 , Y10S514/943
摘要： A method is provided for individuals under treatment for or at risk of atherosclerotic, vascular, cardiovascular, and/or thrombotic disease by administering a composition which comprises a protein source; a carbohydrate source; and at least one lipid selected from the group consisting of: gamma-linolenic acid; eicosapentaenoic acid; docosahexaenoic acid; sterodonic acid; and linolenic acid. Both an enteral and parenteral composition are provided.
摘要翻译：通过施用包含蛋白质来源的组合物，为治疗或处于动脉粥样硬化，血管，心血管和/或血栓形成疾病风险的个体提供了一种方法; 碳水化合物来源; 和至少一种选自以下的脂质：γ-亚麻酸; 二十碳五烯酸二十二碳六烯酸甾体酸和亚麻酸。提供肠内和肠胃外组合物。

6. 发明授权

US09398776B2 Nutritional supplements for 50+ individuals for improving vitality, immunity, eye and bone health 有权
标题翻译：营养补充剂为50多个人提高活力，免疫力，眼睛和骨骼健康
公开(公告)号：US09398776B2
公开(公告)日：2016-07-26
申请号：US13145684
申请日：2010-01-21
申请人： Richard Cotter , Charles Mohs , Lisa Dispensa , Paula Ziegler
发明人： Richard Cotter , Charles Mohs , Lisa Dispensa , Paula Ziegler
IPC分类号： A23L1/29 , A23L1/30 , A61K31/07 , A61K31/122 , A61K31/355 , A61K31/375 , A61K31/51 , A61K31/525 , A61K31/59 , A23L1/302 , A23L1/304
CPC分类号： A23L1/296 , A23L33/15 , A23L33/16 , A23L33/40 , A61K31/07 , A61K31/122 , A61K31/355 , A61K31/375 , A61K31/51 , A61K31/525 , A61K31/59
摘要： A nutritional supplement for adults fifty years and older, and methods of use thereof, are provided that are designed to be most effective in optimizing health, improving vitality and immunity, and improving, aiding, eye and bone health.
摘要翻译：提供五十岁以上成年人的营养补充剂及其使用方法，其被设计为在优化健康，改善活力和免疫力以及改善，帮助，眼睛和骨骼健康方面最有效。

7. 发明申请

US20110280955A1 Nutritional Supplements For 50+ Individuals For Improving Vitality, Immunity, Eye And Bone Health 有权
标题翻译：营养补充剂为50+个人提高活力，免疫力，眼睛和骨骼健康
公开(公告)号：US20110280955A1
公开(公告)日：2011-11-17
申请号：US13145684
申请日：2010-01-21
申请人： Richard Cotter , Charles Mohs , Lisa Dispensa , Paula Ziegler
发明人： Richard Cotter , Charles Mohs , Lisa Dispensa , Paula Ziegler
IPC分类号： A61K33/42 , A61P27/02 , A61P19/00
CPC分类号： A23L1/296 , A23L33/15 , A23L33/16 , A23L33/40 , A61K31/07 , A61K31/122 , A61K31/355 , A61K31/375 , A61K31/51 , A61K31/525 , A61K31/59
摘要： A nutritional supplement for adults fifty years and older, and methods of use thereof, are provided that are designed to be most effective in optimizing health, improving vitality and immunity, and improving, aiding, eye and bone health.
摘要翻译：提供五十岁以上成年人的营养补充剂及其使用方法，其被设计为在优化健康，改善活力和免疫力以及改善，帮助，眼睛和骨骼健康方面最有效。

8. 发明申请

US20110274791A1 MULTIVITAMIN/MINERAL FORMULATION TO COMBAT THE EFFECTS OF ENVIRONMENTAL STRESS; IMPROVED IMMUNITY AND IMPROVE ENERGY WHILE ADDRESSING VITAMIN AND MINERAL DEFICIENCIES WITHOUT THE NEGATIVE SIDE EFFECTS OF A MEGA DOSE NUTRITIONAL SUPPLEMENT 审中-公开
标题翻译：多激素/矿物质配方，以应对环境压力的影响; 改善免疫力，提高维生素和矿物质缺乏的能量，而不产生大剂量营养补充剂的负面影响
公开(公告)号：US20110274791A1
公开(公告)日：2011-11-10
申请号：US13145806
申请日：2010-01-21
申请人： Richard Cotter , Charles Mohs , Lisa Dispensa , Paula Ziegler
发明人： Richard Cotter , Charles Mohs , Lisa Dispensa , Paula Ziegler
IPC分类号： A23L1/302 , A23L1/304 , A23L1/303
CPC分类号： A61K31/33 , A23L33/15 , A61K45/06 , A61K2300/00
摘要： A nutritional supplement, and methods of use thereof, are provided that are designed to be most effective in optimizing health, improving energy and appearance, reducing the effects of environmental stress and improving, aiding, assisting a person's immunity, including but not limited to decreasing the instances, duration and severity of cold infections.
摘要翻译：提供营养补充剂及其使用方法，其被设计为在优化健康，改善能量和外观方面最有效，减少环境压力的影响和改善，帮助辅助个人的免疫力，包括但不限于减少感冒的实例，持续时间和严重程度。

9. 发明申请

US20070269531A1 Non-Steroid Anti-Inflammatory Agents with Vitamins, Minerals, and Dietary Supplements for the Prevention and Treatment of Primary, Secondary and Tertiary Cancer 审中-公开
标题翻译：含有维生素，矿物质和膳食补充剂的非类固醇抗炎药物用于预防和治疗小学，中学和第三纪癌症
公开(公告)号：US20070269531A1
公开(公告)日：2007-11-22
申请号：US11596360
申请日：2005-05-13
申请人： M. Wolfe , Richard Cotter , Alexandra Kropotova
发明人： M. Wolfe , Richard Cotter , Alexandra Kropotova
IPC分类号： A61K38/16 , A61K36/906
CPC分类号： A61K31/415 , A61K45/06 , A61K2300/00
摘要： A composition and method for prevention or treatment of cancer The composition comprises a non-steroid anti-inflammatory agent and at least one of nutritional supplement and/or chemotherapeutic agent.
摘要翻译：用于预防或治疗癌症的组合物和方法该组合物包含非类固醇抗炎剂和营养补充剂和/或化学治疗剂中的至少一种。

10. 发明授权

US5919822A Use of short chain fatty acid containing lipids to maintain gastrointestinal integrity and function in patients 失效
标题翻译：使用短链脂肪酸含脂质维持胃肠道完整性和功能
公开(公告)号：US5919822A
公开(公告)日：1999-07-06
申请号：US831627
申请日：1992-02-06
申请人： Richard Cotter , Hugh Tucker
发明人： Richard Cotter , Hugh Tucker
IPC分类号： A61K9/107 , A61K31/19 , A61K31/22 , A61P1/00 , A61K31/20 , A61K9/10 , A61K31/23 , A61K47/44
CPC分类号： A61K31/22 , A61K31/19 , Y10S514/937 , Y10S514/943
摘要： A method for the use of short chain fatty acids containing lipids in clinical nutrition to maintain gastrointestinal integrity and function in conditions where normal short chain fatty acid substrates, provided by bacterial fermentation of carbohydrates, is inadequate due to the clinical condition of the patient. By providing the short chain fatty acid in a lipid form of free fatty acid, triglyceride, diglyceride, monoglyceride, phospholipid, or cholesterol ester one is able to avoid the clinical defect and allow the gastrointestinal tract to continue to maintain its integrity and function. The short chain fatty acids of the present invention can be provided either in enteral preparations or parenteral preparations.The short chain fatty acids can be provided by hydrolysis of a structure such as: ##STR1## wherein R--COO--, R'--COO--, and R"--COO-- represent either the same or different short chain fatty acids.
摘要翻译：在临床营养中使用含有脂质的短链脂肪酸的方法，用于在通过碳水化合物的细菌发酵提供的正常短链脂肪酸底物由于患者的临床状况而不足的条件下维持胃肠完整性和功能。通过提供游离脂肪酸的脂质形式的短链脂肪酸，甘油三酯，甘油二酯，甘油单酯，磷脂或胆固醇酯，能够避免临床缺陷，并允许胃肠道继续保持其完整性和功能。本发明的短链脂肪酸可以在肠内制剂或肠胃外制剂中提供。短链脂肪酸可以通过以下结构的水解提供：其中R-COO-，R'-COO-和R“ - COO-代表相同或不同的短链脂肪酸。

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