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1. 发明授权

US08515221B2 Silicon optical bench OCT probe for medical imaging 有权
标题翻译：硅光学台用于医学成像的OCT探针
公开(公告)号：US08515221B2
公开(公告)日：2013-08-20
申请号：US12693181
申请日：2010-01-25
申请人： Dale C. Flanders , James W. Getz , Walid A. Atia , Peter S. Whitney , Mark E. Kuznetsov
发明人： Dale C. Flanders , James W. Getz , Walid A. Atia , Peter S. Whitney , Mark E. Kuznetsov
IPC分类号： G02B6/26
CPC分类号： G01Q60/22 , A61B5/0066 , A61B5/0084 , A61B5/02007 , A61B2562/12 , G02B23/2469
摘要： An optical probe for emitting and/or receiving light within a body comprises an optical fiber that transmits and/or receives an optical signal, a silicon optical bench including a fiber groove running longitudinally that holds an optical fiber termination of the optical fiber and a reflecting surface that optically couples an endface of the optical fiber termination to a lateral side of the optical bench. The fiber groove is fabricated using silicon anisotropic etching techniques. Some examples use a housing around the optical bench that is fabricated using LIGA or other electroforming technology. A method for forming lens structure is also described that comprises forming a refractive lens in a first layer of a composite wafer material, such as SOI (silicon on insulator) wafers and forming an optical port through a backside of the composite wafer material along an optical axis of the refractive lens. the refractive lens is preferably formed using grey-scale lithography and dry etching the first layer.
摘要翻译：用于在体内发射和/或接收光的光学探针包括传输和/或接收光信号的光纤，包括纵向延伸的光纤槽的硅光学台，其保持光纤的光纤端接和反射表面，其将光纤端接件的端面光学耦合到光学平台的侧面。使用硅各向异性蚀刻技术制造纤维槽。一些例子使用使用LIGA或其他电铸技术制造的光学平台周围的外壳。还描述了一种用于形成透镜结构的方法，其包括在诸如SOI（绝缘体上硅）晶片的复合晶片材料的第一层中形成折射透镜，并且沿着光学器件通过复合晶片材料的背面形成光学端口折射透镜的轴线。折射透镜优选使用灰度光刻形成并且对第一层进行干蚀刻。

2. 发明申请

US20090059971A1 Linearized Swept Laser Source for Optical Coherence Analysis System 审中-公开
标题翻译：用于光学相干分析系统的线性扫描激光源
公开(公告)号：US20090059971A1
公开(公告)日：2009-03-05
申请号：US12027710
申请日：2008-02-07
申请人： Walid A. Atia , Mark E. Kuznetsov , Dale C. Flanders
发明人： Walid A. Atia , Mark E. Kuznetsov , Dale C. Flanders
IPC分类号： H01S3/10
CPC分类号： H01S5/141 , G01N21/4795 , H01S5/02284 , H01S5/0683 , H01S5/0687
摘要： A frequency swept laser source that generates an optical signal that is tuned over a spectral scan band at single discrete wavelengths associated with longitudinal modes of the swept laser source. Laser hopping over discrete single cavity modes allows long laser coherence length even under dynamic very high speed tuning conditions. A ramp drive to the laser is used to linearize laser frequency tuning. A beam splitter is used to divide the optical signal between a reference arm leading to a reference reflector and a sample arm leading to a sample. A detector system detects the optical signal from the reference arm and the sample arm for generating depth profiles and images of the sample.
摘要翻译：频率扫描激光源，其产生在与扫描的激光源的纵向模式相关联的单独离散波长下在光谱扫描带上调谐的光信号。在离散单腔模式下的激光跳跃即使在动态非常高速的调谐条件下也能实现长激光相干长度。激光器的斜坡驱动用于线性化激光频率调谐。分束器用于将通向参考反射器的参考臂和通向样品的样品臂之间的光信号分开。检测器系统检测来自参考臂和样品臂的光信号，用于产生样品的深度分布和图像。

3. 发明授权

US07482589B2 Method and system for noise control in semiconductor spectroscopy system 有权
标题翻译：半导体光谱系统噪声控制方法与系统
公开(公告)号：US07482589B2
公开(公告)日：2009-01-27
申请号：US11550503
申请日：2006-10-18
申请人： Dale C. Flanders , Walid A. Atia , Mark E. Kuznetsov
发明人： Dale C. Flanders , Walid A. Atia , Mark E. Kuznetsov
IPC分类号： G01J5/02 , H01S3/10
CPC分类号： G01N21/39 , G01J1/32 , G01J3/02 , G01J3/0218 , G01J3/0224 , G01J3/0256 , G01J3/10 , G01J3/26 , G01J3/4338 , G01J2003/1286 , H01S3/08013 , H01S3/083 , H01S5/005 , H01S5/0064 , H01S5/0085 , H01S5/02248 , H01S5/02252 , H01S5/06817 , H01S5/0683 , H01S5/1071 , H01S5/141 , H01S2301/02
摘要： An optical power control system for a semiconductor source spectroscopy system controls power fluctuations in the tunable signal from the spectroscopy system and thus improves the noise performance of the system. This general solution has advantages relative to other systems that simply detect reference power levels during the scan and then correct the detected signal after interaction with the sample by reducing the requirements for coordinating the operation of the sample detectors and power or reference detectors. The spectroscopy system comprises a semiconductor source and a tunable filter. The combination of the semiconductor source and tunable signal illuminate a sample with a tunable signal, being tunable over a scan band. The power control system comprises an amplitude detector system for detecting the power of the tunable optical signal and power control system for regulating the amplitude of the tunable optical signal in response to its detected power.
摘要翻译：用于半导体源光谱系统的光功率控制系统控制来自光谱系统的可调谐信号中的功率波动，从而改善系统的噪声性能。该通用解决方案相对于在扫描期间简单地检测参考功率电平然后在与样品相互作用之后校正检测到的信号的其它系统具有优点，通过减少协调样品检测器和功率或参考检测器的操作的要求。光谱系统包括半导体源和可调谐滤波器。半导体源和可调信号的组合用可调信号照射样品，可在扫描带上调谐。功率控制系统包括用于检测可调谐光信号的功率的振幅检测器系统和用于响应于其检测到的功率来调节可调谐光信号的幅度的功率控制系统。

4. 发明授权

US07292344B2 Integrated spectroscopy system 有权
标题翻译：综合光谱系统
公开(公告)号：US07292344B2
公开(公告)日：2007-11-06
申请号：US11380684
申请日：2006-04-28
申请人： Walid A. Atia , Dale C. Flanders , Petros Kotidis , Mark E. Kuznetsov
发明人： Walid A. Atia , Dale C. Flanders , Petros Kotidis , Mark E. Kuznetsov
IPC分类号： G01B9/02 , G01J3/45
CPC分类号： G01J3/36 , G01J3/0256 , G01J3/10 , G01J3/26 , G01N21/255
摘要： Integrated spectroscopy systems are disclosed. In some examples, integrated tunable detectors, using one or multiple Fabry-Perot tunable filters, are provided. Other examples use integrated tunable sources. The tunable source combines one or multiple diodes, such as superluminescent light emitting diodes (SLED), and a Fabry Perot tunable filter or etalon. The advantages associated with the use of the tunable etalon are that it can be small, relatively low power consumption device. For example, newer microelectrical mechanical system (MEMS) implementations of these devices make them the size of a chip. This increases their robustness and also their performance. In some examples, an isolator, amplifier, and/or reference system is further provided integrated.
摘要翻译：公开了集成光谱系统。在一些示例中，提供使用一个或多个法布里 - 珀罗可调滤波器的集成可调谐检测器。其他示例使用集成的可调源。可调谐源组合了一个或多个二极管，例如超发光发光二极管（SLED）和法布里珀罗可调滤波器或标准具。与可调谐标准具的使用相关的优点是它可以是小的，相对较低的功率消耗装置。例如，这些器件的较新的微电机械系统（MEMS）实现使其成为芯片的尺寸。这增加了它们的稳健性和性能。在一些示例中，还集成了隔离器，放大器和/或参考系统。

5. 发明授权

US07157712B2 Method and system for noise control in semiconductor spectroscopy system 有权
标题翻译：半导体光谱系统噪声控制方法与系统
公开(公告)号：US07157712B2
公开(公告)日：2007-01-02
申请号：US10953046
申请日：2004-09-29
申请人： Dale C. Flanders , Walid A. Atia , Mark E. Kuznetsov
发明人： Dale C. Flanders , Walid A. Atia , Mark E. Kuznetsov
IPC分类号： G01N21/35
CPC分类号： G01N21/39 , G01J1/32 , G01J3/02 , G01J3/0218 , G01J3/0224 , G01J3/0256 , G01J3/10 , G01J3/26 , G01J3/4338 , G01J2003/1286 , H01S3/08013 , H01S3/083 , H01S5/005 , H01S5/0064 , H01S5/0085 , H01S5/02248 , H01S5/02252 , H01S5/06817 , H01S5/0683 , H01S5/1071 , H01S5/141 , H01S2301/02
摘要： An optical power control system for a semiconductor source spectroscopy system controls power fluctuations in the tunable signal from the spectroscopy system and thus improves the noise performance of the system. This general solution has advantages relative to other systems that simply detect reference power levels during the scan and then correct the detected signal after interaction with the sample by reducing the requirements for coordinating the operation of the sample detectors and power or reference detectors. The spectroscopy system comprises a semiconductor source and a tunable filter. The combination of the semiconductor source and tunable signal illuminate a sample with a tunable signal, being tunable over a scan band. The power control system comprises an amplitude detector system for detecting the power of the tunable optical signal and power control system for regulating the amplitude of the tunable optical signal in response to its detected power.
摘要翻译：用于半导体源光谱系统的光功率控制系统控制来自光谱系统的可调谐信号中的功率波动，从而改善系统的噪声性能。该通用解决方案相对于在扫描期间简单地检测参考功率电平然后在与样品相互作用之后校正检测到的信号的其它系统具有优点，通过减少协调样品检测器和功率或参考检测器的操作的要求。光谱系统包括半导体源和可调谐滤波器。半导体源和可调信号的组合用可调信号照射样品，可在扫描带上调谐。功率控制系统包括用于检测可调谐光信号的功率的振幅检测器系统和用于响应于其检测到的功率来调节可调谐光信号的幅度的功率控制系统。

6. 发明申请

US20120162659A1 Integrated Dual Swept Source for OCT Medical Imaging 有权
标题翻译：用于OCT医疗成像的集成双扫描源
公开(公告)号：US20120162659A1
公开(公告)日：2012-06-28
申请号：US12980144
申请日：2010-12-28
申请人： Brian Goldberg , Dale C. Flanders , Walid A. Atia , Bartley C. Johnson , Mark E. Kuznetsov
发明人： Brian Goldberg , Dale C. Flanders , Walid A. Atia , Bartley C. Johnson , Mark E. Kuznetsov
IPC分类号： G01B9/02 , H01S3/081
CPC分类号： G01B9/02091 , A61B5/0066 , A61B5/0075 , G01N21/4795 , H01S5/02216 , H01S5/02248 , H01S5/02284 , H01S5/141 , H01S5/4012 , H01S5/4062 , H01S5/4068
摘要： An optical coherence analysis system comprising: a first swept source that generates a first optical signal that is tuned over a first spectral scan band, a second swept source that generates a second optical signal that is tuned over a second spectral scan band, a combiner for combining the first optical signal and the second optical signal for form a combined optical signal, an interferometer for dividing the combined optical signal between a reference arm leading to a reference reflector and a sample arm leading to a sample, and a detector system for detecting an interference signal generated from the combined optical signal from the reference arm and from the sample arm. In embodiments, the swept sources are tunable lasers that have shared laser cavities.
摘要翻译：一种光学相干分析系统，包括：第一扫描光源，其产生在第一光谱扫描带上调谐的第一光信号，产生在第二光谱扫描带上调谐的第二光信号的第二扫描光源，组合第一光信号和第二光信号以形成组合的光信号，用于将导通到参考反射器的参考臂与通向样本的采样臂之间的组合光信号分开的干涉仪，以及用于检测由来自参考臂和来自采样臂的组合光信号产生的干扰信号。在实施例中，扫描光源是具有共享激光腔的可调激光器。

7. 发明授权

US07324569B2 Method and system for spectral stitching of tunable semiconductor sources 有权
标题翻译：可调谐半导体源的光谱拼接方法和系统
公开(公告)号：US07324569B2
公开(公告)日：2008-01-29
申请号：US10954616
申请日：2004-09-30
申请人： Dale C. Flanders , Walid A. Atia , Mark E. Kuznetsov
发明人： Dale C. Flanders , Walid A. Atia , Mark E. Kuznetsov
IPC分类号： H01S3/10
CPC分类号： G01J3/10
摘要： A multi semiconductor source tunable spectroscopy system has two or more semiconductor sources for generating tunable optical signals that are tunable over different spectral bands. The system enables the combination of these tunable signals to form an output signal that is tunable over a combined band including these individual spectral bands of the separate semiconductor sources. The system further compensates for spectral roll-off associated with the semiconductor sources. Specifically, near the limits of the semiconductor sources' spectral bands, the power in the tunable signal tends to degrade or decrease. The system compensates for this roll-off using drive current control, attenuators, or electronic compensation.
摘要翻译：多半导体源可调谐光谱系统具有用于产生可调谐光信号的两个或更多个半导体源，其可调谐的不同光谱带。该系统使得这些可调谐信号的组合能够形成可在包括单独半导体源的这些单个频谱带的组合频带上调谐的输出信号。该系统进一步补偿与半导体源相关联的光谱滚降。具体来说，在半导体光源频带的极限附近，可调信号的功率趋于降低或降低。该系统使用驱动电流控制，衰减器或电子补偿来补偿此滚降。

8. 发明授权

US07061618B2 Integrated spectroscopy system 有权
公开(公告)号：US07061618B2
公开(公告)日：2006-06-13
申请号：US10688690
申请日：2003-10-17
申请人： Walid A. Atia , Dale C. Flanders , Petros Kotidis , Mark E. Kuznetsov
发明人： Walid A. Atia , Dale C. Flanders , Petros Kotidis , Mark E. Kuznetsov
IPC分类号： G01B9/02
CPC分类号： G01J3/36 , G01J3/0256 , G01J3/10 , G01J3/26 , G01N21/255
摘要： Integrated spectroscopy systems are disclosed. In some examples, integrated tunable detectors, using one or multiple Fabry-Perot tunable filters, are provided. Other examples use integrated tunable sources. The tunable source combines one or multiple diodes, such as superluminescent light emitting diodes (SLED), and a Fabry Perot tunable filter or etalon. The advantages associated with the use of the tunable etalon are that it can be small, relatively low power consumption device. For example, newer microelectrical mechanical system (MEMS) implementations of these devices make them the size of a chip. This increases their robustness and also their performance. In some examples, an isolator, amplifier, and/or reference system is further provided integrated.

9. 再颁专利

USRE44605E1 Integrated spectroscopy system 有权
标题翻译：综合光谱系统
公开(公告)号：USRE44605E1
公开(公告)日：2013-11-19
申请号：US12613349
申请日：2009-11-05
申请人： Walid A. Atia , Dale C. Flanders , Petros Kotidis , Mark E. Kuznetsov
发明人： Walid A. Atia , Dale C. Flanders , Petros Kotidis , Mark E. Kuznetsov
IPC分类号： G01B9/02 , G01J3/45
CPC分类号： G01J3/36 , G01J3/0256 , G01J3/10 , G01J3/26 , G01N21/255
摘要： Integrated spectroscopy systems are disclosed. In some examples, integrated tunable detectors, using one or multiple Fabry-Perot tunable filters, are provided. Other examples use integrated tunable sources. The tunable source combines one or multiple diodes, such as superluminescent light emitting diodes (SLED), and a Fabry Perot tunable filter or etalon. The advantages associated with the use of the tunable etalon are that it can be small, relatively low power consumption device. For example, newer microelectrical mechanical system (MEMS) implementations of these devices make them the size of a chip. This increases their robustness and also their performance. In some examples, an isolator, amplifier, and/or reference system is further provided integrated.
摘要翻译：公开了集成光谱系统。在一些示例中，提供使用一个或多个法布里 - 珀罗可调滤波器的集成可调谐检测器。其他示例使用集成的可调源。可调谐源组合了一个或多个二极管，例如超发光发光二极管（SLED）和法布里珀罗可调滤波器或标准具。与可调谐标准具的使用相关的优点是它可以是小的，相对较低的功率消耗装置。例如，这些器件的较新的微电机械系统（MEMS）实现使其成为芯片的尺寸。这增加了它们的稳健性和性能。在一些示例中，还集成了隔离器，放大器和/或参考系统。

10. 发明授权

US08564783B2 Optical coherence tomography laser with integrated clock 有权
标题翻译：具有集成时钟的光学相干断层扫描激光
公开(公告)号：US08564783B2
公开(公告)日：2013-10-22
申请号：US12396099
申请日：2009-03-02
申请人： Dale C. Flanders , Walid A. Atia , Bartley C. Johnson , Mark E. Kuznetsov , Carlos R. Melendez
发明人： Dale C. Flanders , Walid A. Atia , Bartley C. Johnson , Mark E. Kuznetsov , Carlos R. Melendez
IPC分类号： G01B9/02
CPC分类号： G01B9/02091 , G01B9/02004 , G01B9/02044 , G01B9/02059 , G01B9/02069 , G01B2290/25 , H01S3/08013 , H01S3/08054 , H01S3/1067 , H01S5/02248 , H01S5/02415 , H01S5/068 , H01S5/141 , H01S5/146
摘要： A frequency swept laser source for TEFD-OCT imaging includes an integrated clock subsystem on the optical bench with the laser source. The clock subsystem generates frequency clock signals as the optical signal is tuned over the scan band. Preferably the laser source further includes a cavity extender in its optical cavity between a tunable filter and gain medium to increase an optical distance between the tunable filter and the gain medium in order to control the location of laser intensity pattern noise. The laser also includes a fiber stub that allows for control over the cavity length while also controlling birefringence in the cavity.
摘要翻译：用于TEFD-OCT成像的频率扫描激光源包括具有激光源的光学台上的集成时钟子系统。当光信号在扫描带上调谐时，时钟子系统产生频率时钟信号。优选地，激光源还包括在可调谐滤波器和增益介质之间的光腔中的腔体延长器，以增加可调谐滤波器和增益介质之间的光学距离，以便控制激光强度图案噪声的位置。该激光器还包括一个纤维短截线，其允许控制腔体长度，同时还控制空腔中的双折射。

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