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1. 发明授权

US4216779A Blood pressure monitoring system 失效
标题翻译：血压监测系统
公开(公告)号：US4216779A
公开(公告)日：1980-08-12
申请号：US796893
申请日：1977-05-16
申请人： W. David Squires , Donald L. Anderson , Isaac R. Cherry
发明人： W. David Squires , Donald L. Anderson , Isaac R. Cherry
IPC分类号： A61B5/0225 , A61B5/022 , G06F17/00 , A61B5/02
CPC分类号： A61B5/02208 , A61B5/7285 , Y10S128/90
摘要： Apparatus is disclosed for long-term ambulatory monitoring of blood pressure by an auscultation method, employing a pressurizable cuff and requiring no intervention by the patient. Heartbeats are sensed by ECG electrodes, and a microphone is used to sense the Korotkow sounds as the pressure in the cuff is varied. The presence or absence of a Korotkow sound within a preset interval following each heartbeat is used in determining when the cuff pressure equals the systolic and diastolic pressures. Those pressures are determined in each cycle of operation and are recorded on a continuously-running portable tape recorder, along with the ECG signals. In each cycle of operation, the initial pressure to which the cuff is inflated is based on the systolic pressure measured in the immediately preceding cycle. The pressure in the inflated cuff is thereafter stepped downward in small discrete decrements triggered by successive heartbeats during the measurement phase of each cycle. After both the systolic and diastolic pressures have been determined, the remaining cuff pressure is vented through the same valve that was used to produce the stepwise pressure reduction. After a number of cycles of operation, the magnetic tape is removed from the portable recorder and inserted into an analyzer for high-speed playback and automated plotting of the heart rate and accompanying blood pressure readings on a common chart.
摘要翻译：公开了通过听诊方法对血压进行长期动态监测的装置，其使用可加压的袖带并且不需要患者的干预。 ECG电极感应到心跳，并且当袖带中的压力变化时，麦克风用于感测Korotkow声音。在每个心跳之后的预设间隔内存在或不存在Korotkow声音用于确定袖带压力何时等于收缩压和舒张压。这些压力在每个操作周期中确定，并与ECG信号一起记录在连续运行的便携式磁带录音机上。在每个操作循环中，袖带膨胀的初始压力基于在紧接的前一周期中测得的收缩压。然后，在每个周期的测量阶段，充气袖带中的压力在连续的心跳触发的小的离散衰减中逐步下降。在确定收缩压和舒张压两者之后，剩余的袖带压力通过用于产生逐步减压的相同的阀排出。经过多个周期的操作后，将磁带从便携式记录仪中取出并插入分析仪，用于高速播放，并在公共图表上自动绘制心率和伴随的血压读数。

2. 发明授权

US4123785A Recorder for cardiac signals with manually actuated event marking 失效
标题翻译：具有手动启动事件标记的心脏信号记录仪
公开(公告)号：US4123785A
公开(公告)日：1978-10-31
申请号：US773618
申请日：1977-03-02
申请人： Isaac R. Cherry , Donald L. Anderson
发明人： Isaac R. Cherry , Donald L. Anderson
IPC分类号： A61B5/0436 , A61B5/0452 , G06F17/00 , G11B15/02 , G11B15/29 , G11B15/54 , G11B27/10 , G11B5/00
CPC分类号： G11B27/10 , A61B5/04365 , A61B5/0452 , G11B15/026 , G11B15/29 , G11B15/54
摘要： A miniature tape recorder intended for ambulatory recording of cardiac signals over a twenty-four-hour interval includes a clock with a visual display and an event marking circuit. Cardiac signals are recorded simultaneously on two tracks on the magnetic tape used by the recorder. The event marking circuit, activated by the patient, interrupts briefly the recording of cardiac signals on one of the tracks to record in its place an event marker signal easily recognizable on playback. The event marking circuit includes a clock circuit, a counter, and logic circuits to generate a burst of exactly eight square pulses of predetermined width, the duration of the burst being one second.
摘要翻译：用于在二十四小时间隔间内进行动态记录心脏信号的微型磁带录像机包括具有视觉显示的时钟和事件标记电路。心脏信号同时记录在记录仪使用的磁带上的两个磁道上。患者激活的事件标记电路短暂地中断在其中一条轨道上记录心脏信号，以在其位置记录在重放时容易识别的事件标记信号。事件标记电路包括时钟电路，计数器和逻辑电路，以产生具有预定宽度的正好八个平方脉冲的脉冲串，脉冲串的持续时间为一秒。

3. 发明授权

US4336810A Method and apparatus for arrhythmia analysis of ECG recordings 失效
标题翻译：心电图记录心律失常分析方法与装置
公开(公告)号：US4336810A
公开(公告)日：1982-06-29
申请号：US192192
申请日：1980-09-30
申请人： Donald L. Anderson , Isaac R. Cherry , John A. Ripley , David T. Tanaka
发明人： Donald L. Anderson , Isaac R. Cherry , John A. Ripley , David T. Tanaka
IPC分类号： A61B5/0436 , A61B5/0452 , G06F17/00 , G11B15/48 , A61B5/04
CPC分类号： G11B15/48 , A61B5/04365 , A61B5/0452 , A61B5/04525 , A61B5/7264 , A61B5/7267
摘要： Method and apparatus for arrhythmia analysis of Holter-type ECG recordings including a tape playback unit having an analog signal output of successive ECG complexes or heart beats, a converter for generating data composites representing each complex, a computer for making and storing data templates in bins corresponding to operator classification of complexes as normal, supraventricular ectopic (SVE), ventricular ectopic (VE), or unknown, for comparing successive composites with stored templates and conditions to determine a match condition, and for signaling a corresponding event to an event counter and display. In learn mode the computer signals the tape playback to stop and to display an unmatched complex for operator classification and possible subsequent generation of a new template, after which scanning is resumed.
摘要翻译：包括具有连续ECG复合体或心跳的模拟信号输出的磁带重放单元的心电图记录的心律失常分析方法和装置，用于生成表示每个复合体的数据复合体的转换器，用于在数据仓中制作和存储数据模板的计算机对应于作为正常，室上异位（SVE），室性异位（VE）或未知的复合物的操作者分类，用于将连续复合物与存储的模板和条件进行比较以确定匹配条件，以及用于将事件计数器和/ 显示。在学习模式下，计算机发信号通知磁带播放停止，并显示不可比拟的复合体，以便操作人员进行分类，然后再生成新模板，然后重新开始扫描。

4. 发明授权

US4136690A Method and apparatus for vector analysis of ECG arrhythmias 失效
标题翻译： ECG心律失常的矢量分析方法和装置
公开(公告)号：US4136690A
公开(公告)日：1979-01-30
申请号：US847400
申请日：1977-10-31
申请人： Donald L. Anderson , Isaac R. Cherry
发明人： Donald L. Anderson , Isaac R. Cherry
IPC分类号： A61B5/04 , A61B5/0436 , G06F17/00
CPC分类号： A61B5/0436 , A61B5/04011 , A61B5/7264
摘要： ECG signals from two approximately orthogonal leads are combined in a rectangular-to-polar coordinate converter to obtain signals representing the magnitude and angle of the vector. The vector angle existing at the instant the magnitude of the QRS vector reaches its peak is first identified, and a voltage corresponding to the vector angle is sampled and stored for later use. Secondly, the vector angle existing at the instant the magnitude of the T-wave vector reaches its peak later in the cardiac cycle, is identified, and a voltage corresponding to this second vector angle is sampled and stored. The voltages representing the QRS and the T-wave vector angles are then applied to a differential amplifier to obtain a difference voltage representing the angular difference existing between the two maximal vectors. This angular difference possesses certain characteristics which are diagnostically significant. A classifying circuit determines which one of a number of angular ranges the angular difference falls into. A counter is provided for each angular range to accumulate over successive heartbeats the number of differences which have fallen into each of the angular ranges, and the cumulative counts are displayed.
摘要翻译：来自两个近似正交引线的ECG信号在矩形到极坐标转换器中组合以获得表示矢量的大小和角度的信号。首先确定存在于QRS矢量幅度瞬间的矢量角度，并对与矢量角度相对应的电压进行采样并存储供以后使用。其次，识别在心搏周期之后的T波矢量的大小瞬间存在的矢量角，并对与该第二矢量角相对应的电压进行采样和存储。然后将表示QRS和T波矢量角的电压施加到差分放大器以获得表示存在于两个最大矢量之间的角度差的差电压。这种角度差异具有诊断意义上的某些特征。分类电路确定角度差落入的多个角度范围中的哪一个。为每个角度范围提供一个计数器，以在连续心跳上积累已经落入每个角度范围的差异数，并显示累积计数。

5. 再颁专利

USRE29921E Electrocardiographic computer 失效
标题翻译：心电图机
公开(公告)号：USRE29921E
公开(公告)日：1979-02-27
申请号：US899241
申请日：1978-04-24
申请人： Isaac R. Cherry , Donald L. Anderson
发明人： Isaac R. Cherry , Donald L. Anderson
IPC分类号： A61B5/0436 , A61B5/0452 , G06F17/00 , G11B15/02 , G11B15/29 , G11B15/54 , G11B27/10
CPC分类号： G11B27/10 , A61B5/04365 , A61B5/0452 , G11B15/026 , G11B15/29 , G11B15/54
摘要： A multi-speed ECG magnetic tape scanning device for processing and observing in a relatively short interval of time large quantities of ECG signals from two pairs of ECG leads. The ECG information is recorded on a miniature recorder which the patient carries to record the information for a long period of time, such as 24 hours. The recorder includes a built-in clock with a visible display. The recorder also includes an event marker, which is activated by the patient when the patient experiences an event. The play-back of the ECG information is in real time or at multiple high speed play-back speeds of 30, 60 and 120 times real time. During play-back at high speed, a multi-speed multi-channel paper writer reproduces analog trend data, digital printed data and event marking. The trend information is usually heart rate and ST segment level, so as to produce a scanning of an entire 24 hour information tape in as short a period as 12 minutes. The tape scanning device can run on trend to print out trend to the end of the tape, and then stop automatically. Alternatively, the tape scanning device can run on trend to the end of the tape and then automatically cycle to the beginning of the tape to print-out trend and periodically slow the tape down to real time for the print-out of predetermined events in real time. After each print-out in real time, the playback always goes back to the originally selected trend speed for the continuation of the trend print-out. Various short events may be used to slow the read-out to real time, such as an event marking on the tape which has been activated by the patient. Also, any preselected abnormalities in heart function such as abnormal VE's, SVE's, ST level, rapid heart beat, slow heart rate, etc., may be used to print-out in real time. An arrhythmia computer detects and digitally displays the number of premature ventricular contractions (VE) and superventricular ectopic beats (SVE) and actuates the event markers on a paper writer when the arrhythmia occurrences exceed a predetermined number of occurrences during a predetermined time interval. The event marking may also be used to control the slow down during trend read-out to print out the ECG signals in real time to show the arrhythmia occurrences. The arrhythmia computer includes the ability to select one or a number of parameters to determine the occurrence of an arrhythmia. These parameters may be paired beats, prematurity, width or amplitude.

6. 发明授权

US5205295A Method and apparatus for holter recorder with high resolution signal averaging capability for late potential analysis 失效
标题翻译：用于后期电位分析的高分辨率信号平均功能的手枪记录仪的方法和装置
公开(公告)号：US5205295A
公开(公告)日：1993-04-27
申请号：US932907
申请日：1992-08-18
申请人： Bruce Del Mar , Isaac R. Cherry
发明人： Bruce Del Mar , Isaac R. Cherry
IPC分类号： A61B5/0436 , G06F17/00
CPC分类号： A61B5/04365 , A61B5/7232
摘要： A method and apparatus for an ambulatory electrocardiographic monitoring system for recording, detection, measurement, analysis and plotting of high resolution electrocardiographic data having a modified Holter recorder that performs digital signal averaging of selected signals as well as storing for future playback all ECG beats. The digitally signal averaged beats are correlated with a previously defined correlation coefficient yielding summated results that have eliminated nonrepetitive noise to less than a microvolt. By real time averaging approximately 1000 beats during a 10 to 15 minute period and digitally storing the averaged data, micropotential averaging can be performed several times per hour for up to 24-hours. Analog recordings are precalibrated for accurate amplitude representation as well as providing an option for standard one millivolt calibration pulses at the beginning of the tape. Digital recordings are precalibrated relative to the acceptable levels without the use of a calibration signal. The recordings are downloaded to analysis systems at high speeds. If the recordings are analog they are digitized at a sufficiently high enough resolution to permit analysis of micropotentials. All recorded data is transferred to computer memory and hard disk for further review by the analysis system.
摘要翻译：一种用于记录，检测，测量，分析和绘制高分辨率心电图数据的移动心电图监测系统的方法和装置，其具有执行所选信号的数字信号平均以及存储以用于将来播放所有ECG节拍的改进的Holter记录器。数字信号平均拍子与先前定义的相关系数相关，产生已经将非重要噪声消除到小于微伏的求和结果。在10到15分钟的时间内实时平均约1000次拍摄，并且数字地存储平均数据，可以每小时多次执行多达24小时的微位平均。对于精确的幅度表示，模拟记录被预先校准，以及在磁带开头提供标准的一毫伏校准脉冲的选项。在不使用校准信号的情况下，数字记录相对于可接受的水平进行预先校准。录音以高速下载到分析系统。如果记录是模拟的，它们以足够高的分辨率被数字化，以允许分析微量。所有记录的数据都被传送到计算机内存和硬盘，以便分析系统进一步审查。

7. 发明授权

US5701894A Modular physiological computer-recorder 失效
标题翻译：模块化生理计算机记录仪
公开(公告)号：US5701894A
公开(公告)日：1997-12-30
申请号：US555546
申请日：1995-11-09
申请人： Isaac R. Cherry , John A. Bachman , David T. Tanaka , Hangyick So , Raphael Henkin
发明人： Isaac R. Cherry , John A. Bachman , David T. Tanaka , Hangyick So , Raphael Henkin
IPC分类号： A61B5/00 , A61B5/0432 , G06F19/00
CPC分类号： A61B5/04325 , A61B2560/0475 , G06F19/322 , Y10S128/904
摘要： An ambulatory physiological computer recorder that includes multiple selective plug and play signal input conditioners, a microprocessor system with operating and analyzing software and a removable memory module for data storage. The removable memory module may consist of any non-volatile memory such as IC memory, magnetic memory, optical memory or magneto-optical memory. The removable memory module used in the recorder excludes operating software; the purpose of the removable memory module in the recorder is only to receive and store acquired data. The recorder uses an alpha-numeric LCD display with control buttons for user interface to enter patient ID and recorder functional perimeters. Both operational and selective analysis software is resident in the microprocessor EEPROM memory. Software is installed in the recorder by transfer from an external source via standard serial or parallel links with applicable connectors, or by a plug-in EEPROM. The recorder includes a patient event button and audible alert transducer. The LCD panel includes a display of time-of-day and various alert or error messages. Patient physiological and demographic data that is stored, during recording and during set up in the removable memory module, is normally transferred to an external analyzer by moving the memory module to an external system, or this data can be downloaded directly via standard data links. The acquired patient data can also be formatted in a report style, either in real time or at the end of a recording to directly drive various output devices.
摘要翻译：一种动态生理计算机记录器，包括多个选择性即插即用信号输入调节器，具有操作和分析软件的微处理器系统和用于数据存储的可移动存储器模块。可移动存储器模块可以由诸如IC存储器，磁存储器，光学存储器或磁光存储器的任何非易失性存储器组成。记录仪中使用的可移动存储模块不包括操作软件; 记录器中的可移动存储器模块的目的仅仅是接收和存储获取的数据。录音机使用字母数字液晶显示屏，带有用于用户界面的控制按钮，可输入患者ID和录音机功能周边。操作和选择性分析软件都驻留在微处理器EEPROM存储器中。软件通过标准串行或并行链路与适用的连接器或插入式EEPROM从外部源传输安装在记录仪中。记录器包括患者事件按钮和声音报警传感器。 LCD面板包括时间显示和各种警报或错误信息。在记录期间和在可移动存储器模块中设置期间存储的病人生理和人口统计数据通常通过将存储器模块移动到外部系统而被传送到外部分析器，或者可以通过标准数据链接直接下载该数据。获取的患者数据也可以以报告样式进行格式化，无论是实时还是在记录结束时直接驱动各种输出设备。

8. 外观设计

USD276517S Tape deck top and carrying case base for a tape recorder 失效
公开(公告)号：USD276517S
公开(公告)日：1984-11-27
申请号：US197926
申请日：1980-10-17
申请人： Frank Dekker , Isaac R. Cherry
设计人： Frank Dekker , Isaac R. Cherry

9. 外观设计

USD267798S Tape cartridge 失效
公开(公告)号：USD267798S
公开(公告)日：1983-02-01
申请号：US197927
申请日：1980-10-17
申请人： Frank Dekker , Isaac R. Cherry
设计人： Frank Dekker , Isaac R. Cherry

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