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1. 发明授权

US5701894A Modular physiological computer-recorder 失效
标题翻译：模块化生理计算机记录仪
公开(公告)号：US5701894A
公开(公告)日：1997-12-30
申请号：US555546
申请日：1995-11-09
申请人： Isaac R. Cherry , John A. Bachman , David T. Tanaka , Hangyick So , Raphael Henkin
发明人： Isaac R. Cherry , John A. Bachman , David T. Tanaka , Hangyick So , Raphael Henkin
IPC分类号： A61B5/00 , A61B5/0432 , G06F19/00
CPC分类号： A61B5/04325 , A61B2560/0475 , G06F19/322 , Y10S128/904
摘要： An ambulatory physiological computer recorder that includes multiple selective plug and play signal input conditioners, a microprocessor system with operating and analyzing software and a removable memory module for data storage. The removable memory module may consist of any non-volatile memory such as IC memory, magnetic memory, optical memory or magneto-optical memory. The removable memory module used in the recorder excludes operating software; the purpose of the removable memory module in the recorder is only to receive and store acquired data. The recorder uses an alpha-numeric LCD display with control buttons for user interface to enter patient ID and recorder functional perimeters. Both operational and selective analysis software is resident in the microprocessor EEPROM memory. Software is installed in the recorder by transfer from an external source via standard serial or parallel links with applicable connectors, or by a plug-in EEPROM. The recorder includes a patient event button and audible alert transducer. The LCD panel includes a display of time-of-day and various alert or error messages. Patient physiological and demographic data that is stored, during recording and during set up in the removable memory module, is normally transferred to an external analyzer by moving the memory module to an external system, or this data can be downloaded directly via standard data links. The acquired patient data can also be formatted in a report style, either in real time or at the end of a recording to directly drive various output devices.
摘要翻译：一种动态生理计算机记录器，包括多个选择性即插即用信号输入调节器，具有操作和分析软件的微处理器系统和用于数据存储的可移动存储器模块。可移动存储器模块可以由诸如IC存储器，磁存储器，光学存储器或磁光存储器的任何非易失性存储器组成。记录仪中使用的可移动存储模块不包括操作软件; 记录器中的可移动存储器模块的目的仅仅是接收和存储获取的数据。录音机使用字母数字液晶显示屏，带有用于用户界面的控制按钮，可输入患者ID和录音机功能周边。操作和选择性分析软件都驻留在微处理器EEPROM存储器中。软件通过标准串行或并行链路与适用的连接器或插入式EEPROM从外部源传输安装在记录仪中。记录器包括患者事件按钮和声音报警传感器。 LCD面板包括时间显示和各种警报或错误信息。在记录期间和在可移动存储器模块中设置期间存储的病人生理和人口统计数据通常通过将存储器模块移动到外部系统而被传送到外部分析器，或者可以通过标准数据链接直接下载该数据。获取的患者数据也可以以报告样式进行格式化，无论是实时还是在记录结束时直接驱动各种输出设备。

2. 发明授权

US6117077A Long-term, ambulatory physiological recorder 有权
标题翻译：长期，动态生理记录仪
公开(公告)号：US6117077A
公开(公告)日：2000-09-12
申请号：US235658
申请日：1999-01-22
申请人： Bruce Eugene Del Mar , Raphael Henkin , John A. Bachman
发明人： Bruce Eugene Del Mar , Raphael Henkin , John A. Bachman
IPC分类号： A61B5/0408 , A61B5/0416 , A61B5/0432 , A61B5/00 , A61B5/04
CPC分类号： A61B5/04085 , A61B5/0416 , A61B5/04325 , A61B2560/0412 , A61B2560/0468 , A61B5/04087 , A61B5/7232
摘要： A self contained, compact, long term, ambulatory physiological recorder is designed for mounting directly to the body of a patient, immediately adjacent to the organ or system that is to be monitored, and is adhesively and covertly held there in place and comfortably under clothing by the very transducer, skin electrodes that detect the physiological information to be recorded, and thereby increasing continuity and decreasing artifact by obviating the need for numerous and cumbersome, hanging electrode leads as well as unsightly and cumbersome recorder pouches suspended from shoulder straps or belts.
摘要翻译：独立，紧凑，长期的动态生理记录器被设计用于直接安装在患者体内，紧邻要监测的器官或系统，并且被粘性和隐蔽地保持在适当位置并且舒适地在衣服下通过非常传感器，皮肤电极检测要记录的生理信息，从而通过避免需要许多和麻烦的悬挂电极引线以及悬挂在肩带或皮带上的难看的和繁琐的记录器袋，从而增加连续性和减少伪像。

3. 发明授权

US06251080B1 Self contained ambulatory blood pressure cincture 失效
标题翻译：自我包含动态血压
公开(公告)号：US06251080B1
公开(公告)日：2001-06-26
申请号：US09311664
申请日：1999-05-13
申请人： Raphael Henkin , Edward J. Crespin
发明人： Raphael Henkin , Edward J. Crespin
IPC分类号： A61B500
CPC分类号： A61B5/681 , A61B5/02233 , A61B5/742
摘要： A long term ambulatory blood pressure monitor is disclosed in which all elements of the monitor are compactly and inconspicuously contained in/on a cincture housing mounted on an inflatable arm band fixedly and comfortably positioned on the patient arm. System control and display modules are efficiently placed in a flip top mode on the cincture housing itself and alternatively in a wrist watch mode on the patient wrist. Non volatile EEPROM blood pressure data memory is disposed adjacent EPROM system memory and microprocessor controller circuitry on a compact PCB within the cincture housing along with pneumatic motor/pump and solenoid for inflation/deflation of the arm band to obtain systolic/diastolic blood pressure readings via the oscillatory detection method.
摘要翻译：公开了一种长期动态血压监测器，其中监测器的所有元件紧凑且不显眼地容纳在安装在可充气臂带上的牢固的壳体中/固定地且舒适地定位在患者臂上。系统控制和显示模块有效地放置在镜头壳体本身的翻盖模式中，或者以患者腕部上的手表模式放置。非易失性EEPROM血压数据存储器被设置在紧密的印刷电路板内的EPROM系统存储器和微处理器控制器电路以及气动马达/泵和螺线管，用于臂带的充气/放气，以获得收缩/舒张血压读数振荡检测方法。

4. 发明授权

US5323783A Dynamic ST segment estimation and adjustment 失效
标题翻译：动态ST段估计和调整
公开(公告)号：US5323783A
公开(公告)日：1994-06-28
申请号：US974946
申请日：1992-11-12
申请人： Raphael Henkin , George Kelen
发明人： Raphael Henkin , George Kelen
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452
摘要： A method and apparatus for dynamically estimating the ST segment of a rate varying electrocardiogram by comparing the result yielded from a mathematical relationship between calculated beat averages and a predetermined standard. Typically a table of known heartbeats is made from which means for estimating are created. An average of beat to beat intervals is compared with the means for estimating and the length of the ST segment for any particular beat is derived making it possible to dynamically alter ST segment length for any given heartrate.
摘要翻译：通过比较从计算的拍子平均值和预定标准之间的数学关系得到的结果来动态估计速率变化心电图的ST段的方法和装置。通常已经创建了一个已知心跳表，用于估计的手段被创建。将节拍间隔的平均值与用于估计的装置进行比较，并且导出用于任何特定节拍的ST段的长度，使得可以动态地改变任何给定心率的ST段长度。

5. 发明授权

US06701184B2 Virtual Holter 有权
标题翻译：虚拟动态
公开(公告)号：US06701184B2
公开(公告)日：2004-03-02
申请号：US09944846
申请日：2001-08-31
申请人： Raphael Henkin
发明人： Raphael Henkin
IPC分类号： A61B504
CPC分类号： A61B5/0006 , G06F19/00
摘要： A method for conducting a worldwide, inexpensive and accessible ECG Holter data scanning, processing, and analyzing system by way of obtaining a Holter recording in a conventional manner, then downloading that analog or digital data to a PC, then going online through the PC by way of an ISP, such as DSL, capable of large data transfer, through a USB to tie into a URL web address for a Central Computing Facility with advanced and multifaceted data analysis capability available for short term licensed use, then downloading the Holter data to that URL, then scanning and analyzing the downloaded data at that Central Facility in real time from the remote site, then choosing which alternative analysis sub programs need be run on the stored data, and finally returning the selected Holter analysis to the remote site and tagging, storing, and archiving the raw ECG data and the patient demographics, along with results of the various analyses performed on that data in the Central Facility archives for future access.
摘要翻译：通过以常规方式获得Holter记录，然后将该模拟或数字数据下载到PC，然后通过PC在线通过PC进行在线的方法，用于通过以下方式进行全球，便宜且可访问的ECG Holter数据扫描，处理和分析系统通过USB连接到具有可用于短期许可使用的高级和多方面的数据分析能力的中央计算机设备的URL网址，然后将Holter数据下载到该URL，然后从远程站点实时扫描和分析该中央设施的下载数据，然后选择在存储的数据上运行哪些替代分析子程序，最后将所选的Holter分析返回到远程站点并标记，存储和归档原始ECG数据和患者人口统计学以及在中央设施档案中对该数据执行的各种分析的结果以供将来访问。

6. 发明授权

US5109862A Method and apparatus for spectral analysis of electrocardiographic signals 失效
标题翻译：心电图信号光谱分析方法及装置
公开(公告)号：US5109862A
公开(公告)日：1992-05-05
申请号：US658505
申请日：1991-02-21
申请人： George J. Kelen , Raphael Henkin
发明人： George J. Kelen , Raphael Henkin
IPC分类号： A61B5/0432 , G06F17/00
CPC分类号： A61B5/0432 , A61B5/7253 , A61B5/7257
摘要： A frequency domain signal processing and analysis method and apparatus displays, plots and makes measurements upon electrocardiographic signals (ECG) recorded from the body surface. Both the graphic plots and the numeric parameters measured reveal abnormalities of electrical conduction within the heart thought to be important in the identification of patients at risk of serious disturbances of heart rhythm including sudden death. The invention employs Fourier analysis of short overlapping segments of ECG signal to create a three dimensional map ("spectrocardiogram") whose axes are time, fequency and power thus disclosing changes in the frequency content of the ECG signal over short intervals of time. In additoin to the Fourier analysis itself, the method and apparatus provides a wide choice of user-selectable signal pre-processing, post-processing, display and plotting options as well as performing custom mathematical computations upon the Fourier spectra to distinguish and quantify visually apparent differences between normal and abnormal spectrocardiograms.
摘要翻译：频域信号处理和分析方法和装置显示，绘图并对从身体表面记录的心电图信号（ECG）进行测量。图形图和测量的数值参数都揭示了心脏内电传导的异常，认为在识别患有严重心律紊乱（包括猝死）风险的患者中是重要的。本发明使用ECG信号的短重叠段的傅里叶分析来创建其轴是时间，频率和功率的三维映射（“光谱仪”），从而公开了在短时间间隔内ECG信号的频率含量的变化。此外，傅里叶分析本身，该方法和装置提供了用户可选择的信号预处理，后处理，显示和绘图选项的广泛选择，以及在傅立叶光谱上执行定制数学计算以区分和量化视觉表观正常和异常光谱之间的差异。

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