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1. 发明授权

US4140802A Barley malt sterilization 失效
标题翻译：大麦麦芽灭菌
公开(公告)号：US4140802A
公开(公告)日：1979-02-20
申请号：US828589
申请日：1977-08-26
申请人： Vincent J. Kelly , Paul J. Thompson , Wayne J. Smalligan
发明人： Vincent J. Kelly , Paul J. Thompson , Wayne J. Smalligan
IPC分类号： A23L7/20 , C12C1/16 , A23L1/202
CPC分类号： C12C1/16 , A23L7/20
摘要： A process for sterilizing barley malt by subjecting the barley malt to soaking in an aqueous solution of an organic alcohol containing up to three carbon atoms under ambient temperature conditions, followed by removal of the organic alcohol solution and drying of the treated barley malt at low temperatures.
摘要翻译：一种通过在环境温度条件下使大麦麦芽在含有至多3个碳原子的有机醇的水溶液中浸泡，然后除去有机醇溶液并在低温下干燥处理的大麦麦芽的方法来灭菌大麦芽。

2. 发明授权

US09962278B2 Modular gastrointestinal prostheses 有权
公开(公告)号：US09962278B2
公开(公告)日：2018-05-08
申请号：US13493144
申请日：2012-06-11
申请人： Kedar R. Belhe , Paul J. Thompson
发明人： Kedar R. Belhe , Paul J. Thompson
IPC分类号： A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要： A modular system for therapy within a gastrointestinal system. The system includes anchoring or attachment functionality embodied in a low-profile implant technology and removable therapy components, which can be reversibly attached to these low-profile implants to accomplish various therapies. This modular design allows the physician to tailor the therapy to the patient's needs. The modular system has the potential to create conduits for diversion and/or restriction of food and organ secretions and to facilitate the treatment of metabolic disorders such as obesity and T2DM.

3. 发明授权

US08900289B2 Stent with dual support structure 有权
标题翻译：支架双支撑结构
公开(公告)号：US08900289B2
公开(公告)日：2014-12-02
申请号：US13198770
申请日：2011-08-05
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/06 , A61F2/91 , A61F2/915
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2230/0013 , A61F2230/0054 , A61F2250/001
摘要： A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.
摘要翻译：管腔内支架包括具有未展开直径并且可扩张至扩大直径的网状管。管包括在第一和第二端之间延伸的结构梁。当管从未展开的直径变大到扩大的直径时，结构梁从第一几何变化到第二几何形状。结构梁包括第一和第二纵向元件，每个第一和第二纵向元件至少部分地在第一和第二端之间延伸并且在第一和第二元件之间具有间隔。当管从未展开的直径改变到扩大的直径时，所述第一和第二元件中的每一个从第一几何形状变化到第二几何形状，以使间隔保持基本上不变，因为管从未展开的直径变大到扩大的直径直径。

4. 发明授权

US08702641B2 Gastrointestinal prostheses having partial bypass configurations 有权
标题翻译：具有部分旁路构造的胃肠假体
公开(公告)号：US08702641B2
公开(公告)日：2014-04-22
申请号：US12986268
申请日：2011-01-07
申请人： Kedar R. Belhe , Paul J. Thompson
发明人： Kedar R. Belhe , Paul J. Thompson
IPC分类号： A61B19/00
CPC分类号： A61F5/0076 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要： A system of components may be used separately or in combination to create partial bypass of food, stomach and intestinal secretions and digestive enzymes. The systems are designed to be modular so as to allow the physicians to quickly replace certain elements to tailor the amount of material bypassed, the restriction applied to food passage, and the origin and destination of bypass according to the patient's individualized clinical needs.
摘要翻译：组分体系可以单独使用或组合使用以产生食物，胃和肠分泌物和消化酶的部分旁路。这些系统被设计为模块化的，以便允许医生根据患者的个性化临床需要，迅速地替换某些元件以调整旁路材料的量，应用于食物通过的限制以及旁路的起点和目的地。

5. 发明申请

US20120271406A1 Stent With Enhanced Friction 审中-公开
标题翻译：支架增强摩擦
公开(公告)号：US20120271406A1
公开(公告)日：2012-10-25
申请号：US13535413
申请日：2012-06-28
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61F2/86 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/958 , A61F2002/91541 , A61F2002/91558 , A61F2002/9522 , A61F2002/9583 , A61F2230/0013 , A61F2230/0063 , A61F2230/0069 , A61F2240/001 , A61F2250/0025 , Y10S623/901 , Y10S623/921
摘要： A stent for placement in a body lumen is fabricated by forming a tube having an un-deployed diameter sized for the tube to be placed on a deployment balloon and advanced through a body lumen to a deployment site. The tube is expandable upon inflation of the balloon to an enlarged diameter sized for the tube to be retained within the lumen at the site upon deflation and withdrawal of the balloon. The tube has a stent axis extending between first and second axial ends of the tube. The tube has an exterior surface and an interior surface. The tube is polished to polish the exterior surface to a smooth surface finish and with at least a portion of the interior surface having a rough surface finish rougher than the surface finish of the exterior surface.
摘要翻译：用于放置在体腔中的支架通过形成具有未展开的直径的管来制造，所述管的尺寸适于管放置在展开气囊上并且通过体腔前进到展开部位。当气囊膨胀时，管可膨胀到扩大的直径，其尺寸适于使气囊在气囊收缩和抽出时在该位置保留在管腔内。管具有在管的第一和第二轴向端之间延伸的支架轴线。管具有外表面和内表面。管被抛光以抛光外表面以光滑的表面光洁度，并且内表面的至少一部分具有比外表面的表面光洁度更粗糙的粗糙表面光洁度。

6. 发明申请

US20120065571A1 EXPANDABLE PYLORIC ANCHORS AND METHODS FOR SECURING INTESTINAL BYPASS SLEEVES 审中-公开
标题翻译：可扩展的PYLORIC锚杆及其安装方法
公开(公告)号：US20120065571A1
公开(公告)日：2012-03-15
申请号：US13298867
申请日：2011-11-17
申请人： Paul J. Thompson , Kedar R. Belhe , Alex Grafov
发明人： Paul J. Thompson , Kedar R. Belhe , Alex Grafov
IPC分类号： A61M5/00
CPC分类号： A61F5/0076 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要： A gastrointestinal device for implanting within a patient's gastrointestinal tract includes first and second expandable anchoring rings configured to be disposed on either side of a patient's pylorus. The first expandable anchoring ring has a collapsed configuration and an expanded configuration, wherein in the expanded configuration the first expandable anchoring ring has a diameter larger than a maximum opening diameter of the pylorus. The second expandable anchoring ring also has a collapsed configuration and an expanded configuration, wherein in the expanded configuration the second expandable anchoring ring has a diameter larger than a maximum opening diameter of the pylorus. An intestinal bypass sleeve couples the first expandable anchoring ring and the second expandable anchoring ring, so as to allow a distance between the anchoring rings to exceed a width of the pylorus.
摘要翻译：用于植入患者胃肠道内的胃肠装置包括被配置为设置在患者幽门的任一侧上的第一和第二可扩张锚定环。第一可膨胀锚固环具有收缩构型和膨胀构型，其中在膨胀构型中，第一可膨胀锚定环的直径大于幽门的最大开口直径。第二可膨胀锚固环还具有收缩构型和膨胀构型，其中在膨胀构型中，第二可膨胀锚定环的直径大于幽门的最大开口直径。肠旁路套管将第一可膨胀锚固环和第二可膨胀锚固环联接，以便允许锚定环之间的距离超过幽门的宽度。

7. 发明申请

US20100228338A1 STENTS WITH TAPERED STRUTS 审中-公开
标题翻译：带扭头的手柄
公开(公告)号：US20100228338A1
公开(公告)日：2010-09-09
申请号：US12611114
申请日：2009-11-02
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/89 , A61F2002/91508 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2210/0014 , A61F2230/0013 , A61F2230/0054 , A61F2250/0036
摘要： A stent may include a stent body having a stent axis. The stent body may include structural members defining openings through the stent body. The structural members are provided with regions having different widths. The relative sizes of the widths are selected to control the length of the stent body as the stent body is radially expanded from an undeployed orientation to a deployed orientation. In one embodiment, the regions having different widths are provided by tapering the widths of selected segments of the structural member.
摘要翻译：支架可以包括具有支架轴线的支架主体。支架主体可以包括限定通过支架主体的开口的结构构件。结构构件设置有具有不同宽度的区域。选择宽度的相对尺寸来控制支架主体的长度，因为支架主体从未部署的取向径向膨胀到展开方向。在一个实施例中，具有不同宽度的区域通过使结构构件的选定段的宽度变窄来提供。

8. 发明申请

US20100087912A1 STENT WITH DUAL SUPPORT STRUCTURE 有权
标题翻译：具有双重支持结构的STENT
公开(公告)号：US20100087912A1
公开(公告)日：2010-04-08
申请号：US12633246
申请日：2009-12-08
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/82
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2230/0013 , A61F2230/0054 , A61F2250/001
摘要： A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.
摘要翻译：管腔内支架包括具有未展开直径并且可扩张至扩大直径的网状管。管包括在第一和第二端之间延伸的结构梁。当管从未展开的直径变大到扩大的直径时，结构梁从第一几何变化到第二几何形状。结构梁包括第一和第二纵向元件，每个第一和第二纵向元件至少部分地在第一和第二端之间延伸并且在第一和第二元件之间具有间隔。当管从未展开的直径改变到扩大的直径时，所述第一和第二元件中的每一个从第一几何形状变化到第二几何形状，以使间隔保持基本上不变，因为管从未展开的直径变大到扩大的直径直径。

9. 发明申请

US20100082090A1 CATHETER SYSTEM WITH SPACER MEMBER 审中-公开
标题翻译：带间隔器的导管系统
公开(公告)号：US20100082090A1
公开(公告)日：2010-04-01
申请号：US12608159
申请日：2009-10-29
申请人： Paul J. Thompson , Richard C. Gunderson
发明人： Paul J. Thompson , Richard C. Gunderson
IPC分类号： A61F2/06
CPC分类号： A61F2/962 , A61F2/95 , A61F2/958 , A61F2/966 , A61F2002/9505 , A61F2002/9517 , A61M25/0021 , A61M25/0043 , A61M25/0045 , A61M25/007
摘要： A stent delivery system includes outer and inner elongated, flexible tubular members each having a distal and proximal ends. The outer tubular member is sized to be passed through the body lumen with the distal end advanced to the deployment site and with the proximal end remaining external of the patient's body for manipulation by an operator. The inner tubular member is sized to be received within the outer tubular member. The inner tubular member has a stent attachment location at its distal end. A spacer member is disposed between the inner and outer tubular members. The spacer member maintains spacing between the inner and outer tubular members. Opposing surfaces of the inner and outer tubular members define a passageway extending from the proximal end towards the distal end of the outer tubular member. A fluid exchange port is provided in communication with the passageway at the proximal end of the outer tubular member.
摘要翻译：支架输送系统包括外部和内部细长的柔性管状构件，每个具有远端和近端。外管状构件的尺寸设置成穿过身体内腔，远端前进到展开位置，并且近端保留在患者身体的外部，由操作者操纵。内管状构件的尺寸设置成容纳在外管状构件内。内部管状构件在其远端具有支架附接位置。间隔构件设置在内管状构件和外管状构件之间。隔离构件保持内管状构件和外管状构件之间的间隔。内管状构件和外管状构件的相对表面限定了从外管状构件的近端向远端延伸的通道。流体交换端口设置成与外管状构件的近端处的通道连通。

10. 发明授权

US07211109B2 Braided composite prosthesis 失效
标题翻译：编织复合假体
公开(公告)号：US07211109B2
公开(公告)日：2007-05-01
申请号：US10775961
申请日：2004-02-10
申请人： Paul J. Thompson
发明人： Paul J. Thompson
IPC分类号： A61F2/06
CPC分类号： D04C1/06 , A61B90/39 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2002/072 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2240/001 , D10B2509/06
摘要： A prosthesis for transluminal implantation consists of a flexible tubular interbraided structure of metal or polymeric monofilaments, and polymeric multifilament yarns. The prosthesis can be elastically deformed to reduce its diameter through axial elongation. The monofilaments and multifilament yarns are arranged in axially spaced apart helices, concentric on a common central axis of the prosthesis. The monofilaments are selectively shaped before their interbraiding with the multifilament yarns, either by an age-hardening or other heat-setting stage, or a cold-working stage that controllably plastically deforms the strands. The shaped structural strands cooperate to impart to the prosthesis its nominal shape and resilience. The textile strands cooperate to provide a sheeting that occupies interstices between adjacent structural strands, to reduce permeability and thereby enhance the utility of the prosthesis as a vascular graft. An alternative embodiment prosthesis includes elastically and plastically deformable structural strands, selectively plastically deformed by cold-working then interbraided to form the prosthesis.
摘要翻译：用于腔内植入的假体由金属或聚合单丝的柔性管状插入结构和聚合复丝纱组成。假体可以通过轴向伸长而弹性变形以减小其直径。单丝和复丝纱布置在轴向间隔开的螺旋中，同心于假体的共同中心轴线。单丝在通过时效硬化或其它热定型阶段或可控地塑性地使股线变形的冷加工阶段之前与复丝纱线相互交错而选择成形。成形的结构丝线协作以赋予假体其标称形状和弹性。纺织品线合作提供占据相邻结构链之间间隙的片材，以减少渗透性，从而增强假体作为血管移植物的效用。替代实施例假体包括弹性和塑性变形的结构股，通过冷加工选择性塑性变形，然后插入以形成假体。

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