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    • 5. 发明授权
    • Compositions suitable for the treatment of hair comprising chelants and methods for reducing oxidative hair damage
    • 适用于治疗包含螯合剂的头发的组合物和减少氧化性头发损伤的方法
    • US07186275B2
    • 2007-03-06
    • US10667958
    • 2003-09-22
    • Henry Drummond BoswellJennifer Mary MarshJohn Scott ParkMichael Andrew Olshavsky
    • Henry Drummond BoswellJennifer Mary MarshJohn Scott ParkMichael Andrew Olshavsky
    • A61K7/13
    • A61Q5/10A61K8/44A61K2800/51A61Q5/04A61Q5/08
    • The present invention relates to hair care compositions comprising an oxidizing agent and chelants having log ⁢ ⁢ K CuL log ⁢ ⁢ K CaL ratio calculated at pH 10 of at least 3.20 wherein log KCuL is the common logarithm of the Conditional Stability Constant of said chelant with Cu2+ and log KCaL is the common logarithm of the Conditional Stability Constant of said chelant with Ca2+. Suitable chelants are diamine-N,N′-dipolyacids or monoamine monoamide-N,N′-dipolyacids. The compositions according to the present invention contribute to reducing the oxidative damage sustained by a keratinous fiber such as hair during bleaching, dyeing, perming or other oxidative treatments. Especially preferred diamine dipolyacid is ethylenediamine-N,N′-disuccinic acid (EDDS).
    • 本发明涉及包含氧化剂和螯合剂的头发护理组合物,其具有 日志 K CaL 在pH10下计算的比例至少为3.20,其中log K 是所述螯合剂与Cu 2+的条件稳定常数的常用对数, SUP>和log K 是具有Ca 2+的所述螯合剂的条件稳定常数的常用对数。 合适的螯合剂是二胺-N,N'-二油酸或单胺单酰胺-N,N'-二油酸。 根据本发明的组合物有助于减少在漂白,染色,烫发或其它氧化处理期间由角质纤维如头发持续的氧化损伤。 特别优选的二胺二油酸是乙二胺-N,N'-二琥珀酸(EDDS)。