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    • 8. 发明申请
    • METHOD AND DEVICE FOR HOMOGENISING A FIBROUS, VISCOUS FOOD MASS
    • 用于平衡纤维素,粘稠食物质量的方法和装置
    • US20130115354A1
    • 2013-05-09
    • US13811355
    • 2011-07-18
    • Dieter KuhnOskar MilzAndreas Mueller
    • Dieter KuhnOskar MilzAndreas Mueller
    • A01J25/00
    • A01J25/12A01J25/008A23C19/0684
    • A method and system for homogenizing a fibrous, viscous food mass 1, in particular pasta filata, such as mozzarella, for example, wherein a feed quantity of the food mass 1 is initially fed continuously to a homogenizing device comprising a container, wherein in a subsequent step the food mass 1 exiting an outlet gap of the container is fed to a shaping and/or cooling device disposed underneath the container, wherein the shaping and/or cooling device forms a filling gap between two rollers, each of which, in particular, is equipped with a belt, and shapes the food mass 1 into a food strip, wherein the outlet gap of the container is oriented at least substantially parallel to the filling gap, wherein the opening width of the outlet gap 5 and/or the feed quantity are set such that the food mass located in the container can settle for the purpose of homogenization, wherein the fibers of the food mass entering the filling gap are aligned substantially in the processing direction.
    • 纤维状粘性食品1,特别是意大利面食如莫扎里拉的均质化方法和系统,例如,其中食品1的进料量最初连续送入包括容器的均质装置中,其中在 随后的步骤中,离开容器的出口间隙的食物物质1被供给到设置在容器下方的成形和/或冷却装置,其中成形和/或冷却装置在两个辊之间形成填充间隙,每个辊特别地 配备有带,并将食物块1成形为食品条,其中容器的出口间隙至少基本上平行于填充间隙定向,其中出口间隙5和/或进料的开口宽度 数量被设定为使得位于容器中的食物能够均匀化,其中进入填充间隙的食物的纤维基本上在加工方向上排列。
    • 9. 发明授权
    • Tramadol multiple unit formulations
    • 曲马多多单位制剂
    • US06436438B1
    • 2002-08-20
    • US09349564
    • 1999-07-08
    • Helmut MombergerMarc RaberDieter KuhnWolfgang Schmid
    • Helmut MombergerMarc RaberDieter KuhnWolfgang Schmid
    • A61K922
    • A61K31/137A61K9/5078Y10S514/951
    • A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets, wherein each pellet contains (a) a substantially inert core, (b) an active ingredient layer over the inert core, and containing (i) a pharmacologically active particulate active ingredient, (ii) a nonembedding amount of a binder for adhering the active ingredient over the inert core, and optionally (iii) a pharmaceutically acceptable, inert adjuvant, such as colloidal silica, and (c) a coating over the active ingredient layer for retarding the release of the active ingredient from the active ingredient layer into an aqueous body fluid solvent in situ, the nonembedding amount of the binder is suitably from about 1% wt. to about 10% wt. based on the active ingredient layer, the binder in the active ingredient layer is suitably a mixture of ethylcellulose and shellac, in a weight proportion suitably of from about 1: about 9, to from about 9: about 1, the coating for retarding the release suitably contains from about 70% wt. to about 95% wt. based on the coating, of a substantially water-insoluble, pharmacologically inert, particulate material, and a binder; the pharmacologically inert, particulate material is suitably talcum, and the binder in the active ingredient layer is suitably identical to the binder in the coating.
    • 一种多单位口服药物剂型,其在水溶性胶囊中或在片剂中压制的片剂中具有多个丸粒,其中每个丸粒包含(a)基本上惰性的核心,(b)惰性核心上的活性成分层, 并且包含(i)药理学活性的颗粒活性成分,(ii)非固定量的用于将活性成分粘附在惰性核上的粘合剂,以及任选地(iii)药学上可接受的惰性佐剂,例如胶体二氧化硅和( c)活性成分层上的涂层,用于阻止活性成分从活性成分层原位释放到体液溶剂中,非粘合剂量的粘合剂适宜为约1重量% 至约10重量% 基于活性成分层,活性成分层中的粘合剂合适地是乙基纤维素和虫胶的混合物,其重量比适当地为约1:约9至约9:约1,用于延缓释放的涂层 合适地含有约70重量% 至约95重量% 基于涂层,基本上不溶于水的,药理惰性的颗粒材料和粘合剂; 药理学惰性的颗粒材料适当地是滑石粉,并且活性成分层中的粘合剂适当地与涂层中的粘合剂相同。