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1. 发明公开

US20230181657A1 NOVEL LACTIC ACID BACTERIA AND USE THEREOF 审中-公开
公开(公告)号：US20230181657A1
公开(公告)日：2023-06-15
申请号：US17290516
申请日：2019-04-30
申请人： UNIVERSITY- INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY , NAVIPHARM CO.,LTD.
发明人： Dong-Hyun Kim , Myung Joo Han
IPC分类号： A61K35/747 , A61K35/745 , A23L33/135 , C12N1/20 , A61P25/24 , A61P3/04 , A61P19/10
CPC分类号： A61K35/747 , A61K35/745 , A23L33/135 , C12N1/20 , A61P25/24 , A61P3/04 , A61P19/10 , C12R2001/25
摘要： The present disclosure relates to Lactobacillus plantarum NK3 and Bifidobacterium longum NK49, which are novel lactic acid bacteria, and, more particularly, to a composition comprising novel lactic acid bacteria that are useful for the prevention or treatment of female menopausal disorders.

2. 发明授权

US12036253B2 Lactic acid bacteria and use thereof 有权
公开(公告)号：US12036253B2
公开(公告)日：2024-07-16
申请号：US18065497
申请日：2022-12-13
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY , NAVIPHARM CO. LTD
发明人： Dong-Hyun Kim , Myung Joo Han
IPC分类号： A61K35/747 , A61K35/00 , A61K35/745 , A61P3/04 , A61P19/10 , A61P25/24 , C12N1/20 , C12R1/25
CPC分类号： A61K35/745 , A61K35/747 , A61P3/04 , A61P19/10 , A61P25/24 , C12N1/20 , A61K2035/115 , C12R2001/25
摘要： The present invention relates to Lactobacillus plantarum NK3 and Bifidobacterium longum NK49, which are novel lactic acid bacteria and, more particularly, to a composition comprising novel lactic acid bacteria useful for prevention and treatment of inflammatory diseases.

3. 发明授权

US11554146B2 Lactic acid bacteria and use thereof 有权
公开(公告)号：US11554146B2
公开(公告)日：2023-01-17
申请号：US16760689
申请日：2018-04-19
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY , NAVIPHARM CO. LTD
发明人： Dong-Hyun Kim , Myung Joo Han
IPC分类号： A61K35/747 , A61K35/745 , A61K35/00 , C12R1/25
摘要： The present invention relates to Lactobacillus plantarum NK3 and Bifidobacterium longum NK49, which are novel lactic acid bacteria and, more particularly, to a composition comprising novel lactic acid bacteria useful for prevention and treatment of inflammatory diseases.

4. 发明公开

US20230181656A1 NOVEL LACTIC ACID BACTERIA AND USE THEREOF 审中-公开
公开(公告)号：US20230181656A1
公开(公告)日：2023-06-15
申请号：US18065497
申请日：2022-12-13
申请人： University-Industry Cooperation Group of Kyung Hee University , NAVIPHARM CO. LTD
发明人： Dong-Hyun Kim , Myung Joo Han
IPC分类号： A61K35/745 , A61K35/747
CPC分类号： A61K35/745 , A61K35/747 , C12R2001/25
摘要： The present invention relates to Lactobacillus plantarum NK3 and Bifidobacterium longum NK49, which are novel lactic acid bacteria and, more particularly, to a composition comprising novel lactic acid bacteria useful for prevention and treatment of inflammatory diseases.

5. 发明授权

US11660321B2 Method of treatment with lactic acid bacteria 有权
公开(公告)号：US11660321B2
公开(公告)日：2023-05-30
申请号：US16481643
申请日：2018-01-31
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY , NAVIPHARM CO., LTD.
发明人： Dong-Hyun Kim , Myung Joo Han
IPC分类号： A61K35/745 , A23L7/104 , A23L33/135 , A61P37/06 , A61P37/08 , A61P29/00 , C12N1/20 , A21D8/04 , A23C9/127 , A23L2/02 , A23L2/52 , A61K35/747 , C12R1/25 , A61K35/00
CPC分类号： A61K35/745 , A21D8/04 , A23C9/127 , A23L2/02 , A23L2/52 , A23L7/104 , A23L33/135 , A61K35/747 , A61P29/00 , A61P37/06 , A61P37/08 , C12N1/205 , A23V2002/00 , A23Y2220/67 , A23Y2300/55 , A61K2035/115 , C12R2001/25
摘要： A particular Bifidobacterium spp. strain or particular Lactobacillus spp. strain according to the present invention is isolated from excrement of a human or cabbage kimchi, and thus is highly safe and has physiological activities such as an immunity regulatory effect and an inflammation reaction inhibiting effect. Therefore, the particular Bifidobacterium spp. strain or particular Lactobacillus spp. strain according to the present invention may be used as a material for regulating immunity and inhibiting inflammation reactions, and may be also used as a functional food and drug material useful for preventing, alleviating or treating rhinitis, atopy, asthma, etc. which are allergic diseases.

6. 发明申请

US20220323515A1 NOVEL LACTIC ACID BACTERIA AND USE THEREOF 有权
公开(公告)号：US20220323515A1
公开(公告)日：2022-10-13
申请号：US16481643
申请日：2018-01-31
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY , NAVIPHARM CO., LTD.
发明人： Dong-Hyun Kim , Myung Joo Han
IPC分类号： A61K35/745 , C12N1/20 , A61P37/08 , A61P37/06 , A61P29/00 , A61K35/747 , A23L33/135 , A21D8/04 , A23C9/127 , A23L7/104 , A23L2/02 , A23L2/52
摘要： A particular Bifidobacterium spp. strain or particular Lactobacillus spp. strain according to the present invention is isolated from excrement of a human or cabbage kimchi, and thus is highly safe and has physiological activities such as an immunity regulatory effect and an inflammation reaction inhibiting effect. Therefore, the particular Bifidobacterium spp. strain or particular Lactobacillus spp. strain according to the present invention may be used as a material for regulating immunity and inhibiting inflammation reactions, and may be also used as a functional food and drug material useful for preventing, alleviating or treating rhinitis, atopy, asthma, etc. which are allergic diseases.

7. 发明申请

US20150306158A1 LACTIC ACID BACTERIA CAPABLE OF PREVENTING AND/OR TREATING SENESCENCE AND DEMENTIA 审中-公开
标题翻译：可预防和/或治疗感冒和感染的酸性细菌
公开(公告)号：US20150306158A1
公开(公告)日：2015-10-29
申请号：US14421714
申请日：2013-08-16
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人： Dong-Hyun Kim , Myung Joo Han , Il-Hoon Jung , Myung-Ah Jung
IPC分类号： A61K35/747 , C12R1/225 , C12R1/25
CPC分类号： A61K35/747 , A23L33/135 , A61K2035/11 , C12N1/20 , C12R1/225 , C12R1/25
摘要： The present invention provides a novel lactic acid bacterium having antioxidant and anti-aging functions and a dementia alleviation effect, and more specifically, provides Lactobacillus pentosus var. plantarum C29 KCCM11291P and Lactobacillus curvatus C3 KCCM430009. In addition, the present invention provides an antioxidant and anti-aging pharmaceutical composition and a dietary supplement containing the Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 of the present invention as an active ingredient, and a composition for preventing or treating dementia and a dietary supplement for preventing or alleviating dementia, containing Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 as an active ingredient. Additionally, the present invention provides a composition for preventing or treating dementia, containg a fermentation composition, as an active ingredient, fermented by Lactobacullus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009.
摘要翻译：本发明提供了具有抗氧化和抗衰老功能和痴呆减轻作用的新型乳酸菌，更具体地说，提供了戊糖乳酸杆菌（Lactobacillus pentosus var。植物乳杆菌C29KCCM11291P和曲霉菌C3CCCM430009。另外，本发明提供了抗氧化剂和抗老化药物组合物和含有戊糖乳杆菌变种的膳食补充剂。本发明的植物油C29KCCM11291P或曲霉菌C3KCCM430009作为活性成分，以及用于预防或治疗痴呆的组合物和用于预防或缓解含有戊糖乳杆菌变种的痴呆的膳食补充剂。植物乳杆菌C29KCCM11291P或曲霉菌C3CCCM430009作为活性成分。另外，本发明提供了一种用于预防或治疗痴呆的组合物，其包含发酵组合物作为活性成分，由乳酸杆菌变种乳杆菌发酵。植物乳杆菌C29KCCM11291P或曲霉菌C3CCCM430009。

8. 发明申请

US20150231163A1 COMPOSITION FOR PREVENTING OR TREATING COLITIS 审中-公开
标题翻译：用于预防或治疗感染的组合物
公开(公告)号：US20150231163A1
公开(公告)日：2015-08-20
申请号：US14421770
申请日：2013-08-14
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人： Dong-Hyun Kim , Myung Joo Han , Se Eun Jang
IPC分类号： A61K31/7048 , A61K31/7032 , A61K31/4745 , A61K31/704 , A61K36/344 , A61K36/718 , A61K36/88 , A61K35/64
CPC分类号： A61K31/7048 , A23L33/105 , A61K9/08 , A61K9/19 , A61K31/4745 , A61K31/7032 , A61K31/704 , A61K35/63 , A61K35/64 , A61K36/22 , A61K36/344 , A61K36/718 , A61K36/88 , A61K36/8964 , A61K2300/00
摘要： The present invention relates to a novel use of an Anemarrhena asphodeloides Bunge extract and the like, and provides a composition for preventing or treating colitis, including an Anemarrhena asphodeloides Bunge extract, a fraction thereof or a compound isolated therefrom as an active ingredient. In addition, the present invention relates to a novel use of a combined extract of medicinal herbs, and provides a composition for preventing or treating colitis, including an Anemarrhena asphodeloides Bunge extract, a Galla Rhois extract, a Codonopsis lancellata extract, and the like as active ingredients, or including an Anemarrhena asphodeloides Bunge extract, a Coptis japonica Makino extract, and the like as active ingredients. According to the present invention, the Anemarrhena asphodeloides Bunge extract and the like or the combined extract can be used as a food or medical materials constituting a pharmaceutical composition or a nutraceutical composition. The pharmaceutical composition or the nutraceutical composition can be used for preventing or treating acute colitis or chronic colitis, and particularly, can effectively prevent, delay, alleviate or treat inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and the like.
摘要翻译：本发明涉及一种Anemarrhena asphodeloides Bunge提取物的新用途，并提供一种预防或治疗结肠炎的组合物，包括Anemarrhena asphodeloides Bunge提取物，其分数或其分离的化合物作为活性成分。此外，本发明涉及药草组合提取物的新用途，提供了预防或治疗结肠炎的组合物，包括Anemarrhena asphodeloides Bunge提取物，Galla Rhois提取物，Codonopsis lancellata提取物等作为活性成分，或者包括Anemarrhena asphodeloides Bunge提取物，黄连提取物等作为有效成分。根据本发明，可以将Anemarrhena asphodeloides Bunge提取物等或组合的提取物用作构成药物组合物或营养药物组合物的食品或医疗材料。药物组合物或营养药物组合物可用于预防或治疗急性结肠炎或慢性结肠炎，特别是可有效预防，延缓，缓解或治疗炎性肠病（IBD），肠易激综合征（IBS）等。

9. 发明授权

US10874701B2 Lactic acid bacteria capable of preventing and/or treating senescence and dementia 有权
公开(公告)号：US10874701B2
公开(公告)日：2020-12-29
申请号：US15297955
申请日：2016-10-19
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人： Dong-Hyun Kim , Myung Joo Han , Il-Hoon Jung , Myung-Ah Jung
IPC分类号： A61K35/747 , C12N1/20 , C12R1/25 , C12R1/225 , A23L33/135 , A61K35/00
CPC分类号： A61K35/747 , A23L33/135 , C12N1/20 , C12R1/225 , C12R1/25 , A23V2002/00 , A61K2035/11
摘要： The present invention provides a novel lactic acid bacterium having antioxidant and anti-aging functions and a dementia alleviation effect, and more specifically, provides Lactobacillus pentosus var. plantarum C29 KCCM11291P and Lactobacillus curvatus C3 KCCM430009. In addition, the present invention provides an antioxidant and anti-aging pharmaceutical composition and a dietary supplement containing the Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 of the present invention as an active ingredient, and a composition for preventing or treating dementia and a dietary supplement for preventing or alleviating dementia, containing Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 as an active ingredient. Additionally, the present invention provides a composition for preventing or treating dementia, containing a fermentation composition, as an active ingredient, fermented by Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009.

10. 发明授权

US10561691B2 Lactic acid bacteria capable of preventing and/or treating senescence and dementia 有权
公开(公告)号：US10561691B2
公开(公告)日：2020-02-18
申请号：US15641873
申请日：2017-07-05
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人： Dong-Hyun Kim , Myung Joo Han , Il-Hoon Jung , Myung-Ah Jung
IPC分类号： A61K35/747 , A23L33/135 , C12N1/20 , C12R1/225 , C12R1/25 , A61K35/00
摘要： The present invention provides a novel lactic acid bacterium having antioxidant and anti-aging functions and a dementia alleviation effect, and more specifically, provides Lactobacillus pentosus var. plantarum C29 KCCM11291P and Lactobacillus curvatus C3 KCCM430009. In addition, the present invention provides an antioxidant and anti-aging pharmaceutical composition and a dietary supplement containing the Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 of the present invention as an active ingredient, and a composition for preventing or treating dementia and a dietary supplement for preventing or alleviating dementia, containing Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 as an active ingredient. Additionally, the present invention provides a composition for preventing or treating dementia, containg a fermentation composition, as an active ingredient, fermented by Lactobacullus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009.

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