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1. 发明申请

US20190216865A1 LACTIC ACID BACTERIAL STRAINS 审中-公开
公开(公告)号：US20190216865A1
公开(公告)日：2019-07-18
申请号：US16206250
申请日：2018-11-30
申请人： 4D Pharma Research Limited
发明人： Denise KELLY
IPC分类号： A61K35/747 , A23L33/135 , A23K10/18 , C12R1/25 , C12R1/225 , C12R1/23 , C12N1/20
CPC分类号： A61K35/747 , A23K10/18 , A23L33/135 , A23V2002/00 , C12N1/20 , C12R1/225 , C12R1/23 , C12R1/25 , Y02A50/473 , Y02A50/481
摘要： A first aspect of the invention relates to a porcine lactic acid bacterial strain, wherein said bacterial strain is characterised by one or more of the following characteristics: (i) the ability to exhibit antimicrobial activity against E. coli; (ii) the ability to exhibit antimicrobial activity against S. enteritidis; (iii) the ability to suppress inflammation in IPEC cells induced by 12-0-tetradecaboylphorbol-13-acetate (PMA); (iv) the ability to block the attachment or invasion of IPEC cells by S. enteritidis; (v) the ability to block the attachment or invasion of IPEC cells by E. coli; (vi) the absence of antibiotic resistance to one or more antibiotics selected from the following: ampicillin; cefotaxime; chloramphenicol; erythromycin; gentamicin; tetracycline; vancomycin; metronizadole; nalidixic acid; and kanamycin; and (vii) the ability to exhibit heat stability when subjected to three cycles of heating, each cycle comprising heating at a temperature of 70° C. for a period of 15 minutes. Further aspects of the invention relate to compositions comprising said bacterial strains, and therapeutic uses of said bacterial strains.

2. 发明授权

US10058577B2 Thermo-stable strains, products and methods thereof 有权
公开(公告)号：US10058577B2
公开(公告)日：2018-08-28
申请号：US15115446
申请日：2015-09-30
申请人： TRIPHASE PHARMACEUTICALS PVT. LTD.
发明人： Desiraju Aditya , Desiraju Shrilakshmi , Sharieff Irfanulla , Prakash Abhilash
IPC分类号： A61K35/747 , C12R1/23 , C12R1/25 , A23L33/135 , A23L23/00 , A23G1/42 , A21D8/04 , A23G3/36 , A23F3/16
CPC分类号： A61K35/747 , A21D8/04 , A23F3/16 , A23G1/423 , A23G3/366 , A23L23/00 , A23L33/135 , A23V2002/00 , A23Y2220/03 , A23Y2220/67 , A61K2035/115 , C12R1/23 , C12R1/25
摘要： The present disclosure relates to thermo-stable/heat stable strain(s) of micro-organisms, obtaining such thermo-stable strains and incorporating them into food products. These strains are able to survive high temperatures for longer periods of time and thus food products containing such strains are therapeutically effective and beneficial for general health.

3. 再颁专利

USRE46718E1 Compositions comprising Lactobacillus plantarum strains in combination with tannin and new Lactobacillus plantarum strains 有权
公开(公告)号：USRE46718E1
公开(公告)日：2018-02-20
申请号：US13910278
申请日：2013-06-05
申请人： Goran Molin , Siv Ahrné , Bengt Jeppsson
发明人： Goran Molin , Siv Ahrné , Bengt Jeppsson
IPC分类号： C12N1/20 , A01N63/00 , A61K35/747 , A61K31/35 , A61K31/7032 , C12N9/18 , A23L33/135 , C12R1/25
CPC分类号： A61K31/35 , A23L33/135 , A23Y2220/67 , A61K31/7032 , A61K35/747 , C12N1/20 , C12N9/18 , C12R1/25 , C12Y301/0102 , Y10S435/857 , A61K2300/00
摘要： The invention refers to a composition comprising one or more tannase-producing strains of Lactobacillus having the ability to adhere to the human intestinal mucosa in combination with tannin. New tannase-producing strains of Lactobacillus plantarum are a.

4. 发明授权

US09782446B2 Lactobacillus plantarum isolated from leaves of Camellia sinensis 有权
公开(公告)号：US09782446B2
公开(公告)日：2017-10-10
申请号：US15018697
申请日：2016-02-08
申请人： AMOREPACIFIC CORPORATION
发明人： Il Young Kwack , Se Jin You , Tae-Hun Park , Bum Jin Lee , Kye Ho Shin , Jin Oh Chung , Jun Cheol Cho
IPC分类号： A61K35/747 , C12R1/25 , C12N1/20 , A23L29/00 , C12P7/56 , A61K36/82 , A61K35/00
CPC分类号： A61K35/747 , A23L29/065 , A23Y2220/67 , A61K36/82 , A61K2035/115 , C12N1/20 , C12P7/56 , C12R1/25
摘要： Disclosed are novel Lactobacillus plantarum strains as well as a composition containing the novel Lactobacillus plantarum strains or a culture thereof.

5. 发明授权

US09763988B2 Nano-sized kimchi lactic acid bacteria 有权
公开(公告)号：US09763988B2
公开(公告)日：2017-09-19
申请号：US14780123
申请日：2013-05-31
申请人： BIOGENICS KOREA CO., LTD.
发明人： Hyunung Kim
IPC分类号： A61K35/00 , A61K35/747 , C12N1/20 , C12R1/25 , A61K35/74 , A23L19/20 , A23L33/135
CPC分类号： A61K35/747 , A23L19/20 , A23L33/135 , A23V2002/00 , A23Y2220/67 , A61K35/74 , C12N1/20 , C12R1/25
摘要： A nano-sized Lactobacillus plantarum (L. plantarum) nF1 strain isolated from kimchi and which has a particle size distribution of 0.5 to 1.0 μm. Pharmaceutical compositions and functional food compositions comprising the nano-sized L. plantarum nF1 strain may be used to prevent and treat colorectal diseases including colitis and colorectal cancer.

6. 发明申请

US20170035815A1 NOVEL LACTOBACILLUS PLANTARUM AND COMPOSITION CONTAINING SAME 审中-公开
标题翻译：新颖的乳酸杆菌和含有它们的组合物
公开(公告)号：US20170035815A1
公开(公告)日：2017-02-09
申请号：US15254599
申请日：2016-09-01
申请人： CJ CHEILJEDANG CORP.
发明人： Bong Joon KIM , Heon Woong JUNG , Ji Hoon KOH , Tae Jin KIM , Kang-Pyo LEE , Kwang Woo HWANG , Tae Joon WON
IPC分类号： A61K35/747 , C12N1/20 , C12R1/25
CPC分类号： A61K35/747 , A23K10/18 , A23L33/135 , A23V2200/304 , A23V2200/3204 , A23V2200/324 , A23Y2220/67 , A61K8/99 , A61K2035/11 , A61K2035/115 , A61K2800/10 , A61Q19/00 , C12N1/20 , C12R1/25
摘要： The present invention provides Lactobacillus plantarum CJLP55 KCTC 11401BP, a composition for treating bowel disease containing the lactobacillus, and a composition for immunological enhancement containing the lactobacillus.
摘要翻译：本发明提供植物乳杆菌CJLP55KCTC 11401BP，一种用于治疗含有乳杆菌的肠病的组合物，以及含有乳杆菌的免疫增强组合物。

7. 发明申请

US20170020933A9 NOVEL LACTOBACILLUS PLANTARUM AND COMPOSITION COMPRISING SAME 审中-公开
标题翻译：新颖的Lactobacillus植物和包含它们的组合物
公开(公告)号：US20170020933A9
公开(公告)日：2017-01-26
申请号：US14832214
申请日：2015-08-21
申请人： CJ CHEILJEDANG CORP
发明人： BONG JOON KIM , HEON WOONG JUNG , SE HEE HWANG , JIN HEE LEE , KANG-PYO LEE , KWANG WOO HWANG , TAE JOON WON
IPC分类号： A61K35/747 , A23K1/00 , A23L1/30 , A61K8/99 , A61Q19/00
CPC分类号： A61K35/747 , A23K10/18 , A23L33/135 , A23V2002/00 , A23Y2220/67 , A61K8/99 , A61K35/74 , A61Q19/00 , C12R1/25 , A23V2200/3204 , A23V2200/324 , A23V2200/304 , A23V2200/308
摘要： The present invention provides Lactobacillus plantarum CJLP133 KCTC 11403BP, a composition for treating intestinal diseases comprising the lactic acid bacteria, and a composition for enhancing immunity comprising the lactic acid bacteria.
摘要翻译：本发明提供植物乳杆菌CJLP133KCTC11403BP，一种用于治疗包含乳酸菌的肠道疾病的组合物，以及用于增强包含乳酸菌的免疫力的组合物。

8. 发明申请

US20160113286A1 LACTOBACILLUS PLANTARUM STRAIN FOR THE CONTROL OF FIRE BLIGHT 审中-公开
标题翻译： LACTOBACILLUS PLANTARUM菌株控制火灾
公开(公告)号：US20160113286A1
公开(公告)日：2016-04-28
申请号：US14890891
申请日：2014-05-12
申请人： UNIVERSITAT DE GIRONA
发明人： Emilio MONTESINOS SEGUÍ , Anna BONATERRA CARRERAS , Gemma ROSELLO PRADOS , Jesus FRANCES ORTEGA , Laura MONTESINOS BARREDA , Esther BADOSA ROMANO
IPC分类号： A01N63/00 , C12R1/25 , C12N1/20
CPC分类号： A01N63/00 , C12N1/20 , C12R1/25 , A01N63/02
摘要： The present invention relates to the strain Lactobacillus plantarum TC92, as well as to mutants thereof, and to the use of said strain as a pesticide for controlling fire blight in plants of the Rosaceae family. Additional aspects of the invention relate to methods for producing the L. plantarum strain TC92, pesticide compositions containing said strain and an extract of L. plantarum TC92 exhibiting antagonistic activity towards E. amylovora, which is useful for controlling fire blight. The invention further relates to a method for the biological control of fire blight in plants of the Rosaceae family, which comprises treating said plants with the L. plantarum strain TC92 or the extract of L. plantarum TC92.
摘要翻译：本发明涉及植物乳杆菌TC92菌株及其突变体，以及所述菌株用作农药用于控制蔷薇科植物植物中的灭火病害的用途。本发明的另外的方面涉及用于产生植物乳杆菌菌株TC92的方法，含有所述菌株的农药组合物和表现出对淀粉霉的拮抗活性的植物乳杆菌TC92的提取物，其可用于防治火灾。本发明还涉及一种用于生物防治蔷薇科植物中的火灾的方法，其包括用植物乳杆菌菌株TC92或植物乳杆菌TC92的提取物处理所述植物。

9. 发明申请

US20160089428A1 PHARMACEUTICAL PREPARATION COMPRISING A COMBINATION OF STREPTOCOCCUS STRAINS AND LACTOBACILLUS STRAINS 审中-公开
标题翻译：包含结核分枝杆菌菌株和乳杆菌菌株的组合的药物制备
公开(公告)号：US20160089428A1
公开(公告)日：2016-03-31
申请号：US14878743
申请日：2015-10-08
申请人： ESSUM AB
发明人： Kristian ROOS , Eva Grahn HÅKANSSON
IPC分类号： A61K39/085 , A61K35/74 , A61K35/747
CPC分类号： A61K39/085 , A23K10/18 , A23K50/10 , A61K35/74 , A61K35/744 , A61K35/747 , C12N1/20 , C12R1/225 , C12R1/25 , C12R1/46
摘要： A pharmaceutical preparation for prophylaxis against and treatment ofStaphylococcus induced infections or conditions in humans and animals, is disclosed, wherein it comprises a combination of a) one or more viable α-Streptococcus strains chosen from the group consisting of the Streptococcus sanguis II strains having the accession numbers NCIMB 40104, NCIMB 40105, NCIMB 40106, and NCIMB 40873, the Streptococcus mitis strains having the accession numbers NCIMB 40107, and NCIMB 40874, the Streptococcus oralis strains having the accession numbers NCIMB 40875 and NCIMB 40876, the Streptococcus lactis strain L1A having the accession number NCIMB 40157, and one or more variants thereof having the same or essentially , similar effect; and b) one or more viable Lactobacillus strains chosen from the group consisting of the Lactobacillus rhamnosus strain LB21 having the accession number NCIMB 40564, the Lactobacillus plantarum strain LB3 having the accession number N DSM 17852, and the Lactobacillus plantarum strain LB7 having the accession number DSM 17853, and one or more variants thereof having the same or essentially similar effect; in at least one pharmaceutically acceptable medium in which said strains maintain their viability, as well as a kit for and a method of prophylaxis and treatment of Staphylococcus induced infections and conditions, and use
摘要翻译：公开了用于预防和治疗人类和动物中的葡萄球菌诱导的感染或病症的药物制剂，其中其包含以下组合：a）一种或多种活的α-链球菌属菌株的组合，所述α-链球菌菌株选自下组：链球菌II型链球菌登录号NCIMB 40104，NCIMB 40105，NCIMB 40106和NCIMB 40873，登录号为NCIMB 40107的链球菌菌株和NCIMB 40874，口腔链球菌菌株的登录号为NCIMB 40875和NCIMB 40876，乳酸链球菌菌株L1A具有登录号NCIMB 40157及其一个或多个变体具有相同或基本相同的效果; 和b）选自具有登录号NCIMB 40564的鼠李糖乳杆菌菌株LB21，登录号N DSM 17852的植物乳杆菌菌株LB3和具有登录号的植物乳杆菌菌株LB7的一种或多种活的乳杆菌属菌株 DSM 17853及其一种或多种具有相同或基本相似效果的变体; 在其中所述菌株保持其活力的至少一种药学上可接受的培养基中，以及用于预防和治疗葡萄球菌诱导的感染和病症的试剂盒和方法，以及使用

10. 发明申请

US20160067289A1 PROBIOTIC STRAINS FOR USE IN TREATMENT OR PREVENTION OF OSTEOPOROSIS 审中-公开
标题翻译：用于治疗或预防OSTEOPOSOSIS的生物应变
公开(公告)号：US20160067289A1
公开(公告)日：2016-03-10
申请号：US14782138
申请日：2014-04-03
申请人： PROBI AB
发明人： Anna Berggren , Niklas Larsson , Gunilla Önning , Irini Ahrén Lazou , Klara Sjögren , Claes Ohlsson
IPC分类号： A61K35/747 , C12R1/25 , A23L1/30 , C12R1/225
CPC分类号： A61K35/747 , A23L33/135 , A23V2002/00 , C12R1/225 , C12R1/25
摘要： The present invention relates to at least one probiotic strain chosen from Lactobacillus paracasei, or at least one probiotic strain chosen from Lactobacillus paracaseiin combination with at least one probiotic strain chosen from Lactobacillus plantarum, for use in the treatment or prevention of osteoporosis or for use in increasing the absorption of at Ca2+ ions, in a mammal, preferably in a human.
摘要翻译：本发明涉及选自副干酪乳杆菌的至少一种益生菌菌株，或选自副干酪乳杆菌的至少一种益生菌菌株与选自植物乳杆菌的至少一种益生菌菌株组合，用于治疗或预防骨质疏松症或用于在哺乳动物，优选人中增加Ca 2+离子的吸收。

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