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1. 发明申请

US20100075388A1 PLASMID, TRANSFORMANTS AND PROCESS FOR PRODUCTION OF 3- CARBOXYMUCONOLACTONE 有权
标题翻译：等离子体，改性剂和生产3-羧甲基纤维素的方法
公开(公告)号：US20100075388A1
公开(公告)日：2010-03-25
申请号：US12310095
申请日：2007-08-10
申请人： Kohei Mase , Toshihisa Shimo , Naoki Ohara , Yoshihiro Katayama , Kiyotaka Shigehara , Eiji Masai , Masao Fukuda , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
发明人： Kohei Mase , Toshihisa Shimo , Naoki Ohara , Yoshihiro Katayama , Kiyotaka Shigehara , Eiji Masai , Masao Fukuda , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
IPC分类号： C12P7/46 , C12N15/74 , C12N1/21
CPC分类号： C12N9/1007 , C12N9/0008 , C12N9/0069 , C12P17/04
摘要： There is provided a process for industrial production of simple 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone from low molecular mixtures derived from plant components such as vanillin, vanillic acid and protocatechuic acid, via a multistage enzyme reaction.A recombinant plasmid containing a vanillate demethylase gene (vanAB genes), benzaldehyde dehydrogenase gene (ligV gene) and protocatechuate 3,4-dioxygenase gene (pcaHG genes); transformants incorporating the plasmid; and a process for production of 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone characterized by culturing the transformants in the presence of vanillin, vanillic acid, protocatechuic acid or a mixture of two or more thereof.
摘要翻译：提供了通过多级酶反应从由植物成分如香草醛，香草酸和原儿茶酸衍生的低分子混合物工业生产简单的3-羧基 - 顺式，顺式 - 粘酸和/或3-羧基粘土内酯的方法。含有香草脱甲基酶基因（vanab基因），苯甲醛脱氢酶基因（ligV基因）和原儿茶素3,4-双加氧酶基因（pcaHG基因）的重组质粒; 掺入质粒的转化体; 以及生产3-羧基 - 顺式，顺式 - 粘酸和/或3-羧基粘土内酯的方法，其特征在于在香草醛，香草酸，原儿茶酸或其两种或更多种的混合物存在下培养转化体。

2. 发明授权

US08211683B2 Plasmid, transformants and process for production of 3- carboxymuconolactone 有权
标题翻译：质粒，转化体和生产3-羧基粘康酸内酯的方法
公开(公告)号：US08211683B2
公开(公告)日：2012-07-03
申请号：US12310095
申请日：2007-08-10
申请人： Kohei Mase , Toshihisa Shimo , Naoki Ohara , Yoshihiro Katayama , Kiyotaka Shigehara , Eiji Masai , Masao Fukuda , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
发明人： Kohei Mase , Toshihisa Shimo , Naoki Ohara , Yoshihiro Katayama , Kiyotaka Shigehara , Eiji Masai , Masao Fukuda , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
IPC分类号： C12N9/00 , C12N15/00 , C12N1/20
CPC分类号： C12N9/1007 , C12N9/0008 , C12N9/0069 , C12P17/04
摘要： There is provided a process for industrial production of simple 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone from low molecular mixtures derived from plant components such as vanillin, vanillic acid and protocatechuic acid, via a multistage enzyme reaction. A recombinant plasmid containing a vanillate demethylase gene (vanAB genes), benzaldehyde dehydrogenase gene (ligV gene) and protocatechuate 3,4-dioxygenase gene (pcaHG genes); transformants incorporating the plasmid; and a process for production of 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone characterized by culturing the transformants in the presence of vanillin, vanillic acid, protocatechuic acid or a mixture of two or more thereof.
摘要翻译：提供了通过多级酶反应从由植物成分如香草醛，香草酸和原儿茶酸衍生的低分子混合物工业生产简单的3-羧基 - 顺式，顺式 - 粘酸和/或3-羧基粘土内酯的方法。含有香草脱甲基酶基因（vanab基因），苯甲醛脱氢酶基因（ligV基因）和原儿茶素3,4-双加氧酶基因（pcaHG基因）的重组质粒; 掺入质粒的转化体; 以及生产3-羧基 - 顺式，顺式 - 粘酸和/或3-羧基粘土内酯的方法，其特征在于在香草醛，香草酸，原儿茶酸或其两种或更多种的混合物存在下培养转化体。

3. 发明申请

US20100209978A1 GENE-DISRUPTED STRAIN, RECOMBINANT PLASMIDS, TRANSFORMANTS AND PROCESS FOR PRODUCTION OF 3-CARBOXYMUCONOLACTONE 审中-公开
标题翻译：基因破坏菌株，重组菌株，转化体和生产3-羧基肉豆蔻酸酯的方法
公开(公告)号：US20100209978A1
公开(公告)日：2010-08-19
申请号：US12599787
申请日：2008-05-09
申请人： Toshihisa Shimo , Kohei Mase , Yoshihiro Katayama , Eiji Masai , Masao Fukuda , Kiyotaka Shigehara , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
发明人： Toshihisa Shimo , Kohei Mase , Yoshihiro Katayama , Eiji Masai , Masao Fukuda , Kiyotaka Shigehara , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
IPC分类号： C12P7/44 , C12N1/21 , C12N15/63 , C12P17/02
CPC分类号： C12P7/48 , C12N9/0069 , C12P17/04 , C12Y113/11003
摘要： Industrial-scale fermentative production of 3-carboxy-cis,cis-muconic acid from terephthalic acid. Also, a protocatechuate 4,5-ring-cleaving enzyme gene-disrupted strain in which the gene coding for (a) the amino acid sequence set forth in SEQ ID NO: 1 or 3, or (b) the amino acid sequence set forth in SEQ ID NO: 1 or 3 which has a deletion, substitution, addition and/or insertion of one or more amino acids and exhibits protocatechuate 4,5-ring cleavage activity, present in the chromosomal DNA of microbial cells, has been disrupted; recombinant plasmids comprising the Tph gene and protocatechuate 3,4-dioxygenase gene; transformants obtained by introducing the recombinant plasmids into the disrupted strain; and a process for production of 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone characterized by culturing the transformants in the presence of terephthalic acid.
摘要翻译：从对苯二甲酸工业规模发酵生产3-羧基 - 顺式，顺式 - 粘康酸。此外，原儿茶素4,5环切割酶基因破坏的菌株，其中编码（a）SEQ ID NO：1或3所示的氨基酸序列的基因，或（b）阐述的氨基酸序列在具有一个或多个氨基酸的缺失，取代，添加和/或插入并且表现出存在于微生物细胞的染色体DNA中的原儿茶素4,5-环切割活性的SEQ ID NO：1或3已被破坏; 包含Tph基因和原儿茶素3,4-双加氧酶基因的重组质粒; 通过将重组质粒导入破碎的菌株获得的转化体; 以及3-羧基 - 顺式，顺式 - 粘酸和/或3-羧基粘土内酯的制备方法，其特征在于在对苯二甲酸存在下培养转化体。

4. 发明授权

US06340579B1 Gene encoding an alpha-hydroxy-gamma-carboxymuconic acid-epsilon-semialdehyde dehydrogenase 有权
标题翻译：编码α-羟基-γ-羧甲基纤维素-ε-半醛脱氢酶的基因
公开(公告)号：US06340579B1
公开(公告)日：2002-01-22
申请号：US09720817
申请日：2001-01-12
申请人： Eiji Masai , Masao Fukuda , Yoshihiro Katayama , Seiji Nishikawa , Yasushi Hotta
发明人： Eiji Masai , Masao Fukuda , Yoshihiro Katayama , Seiji Nishikawa , Yasushi Hotta
IPC分类号： C12P1706
CPC分类号： C12N9/0008 , C12P7/48 , C12P7/50
摘要： &agr;-Hydroxy-&ggr;-carboxymuconic acid-&egr;-semialdehyde dehydrogenase, a gene encoding the enzyme, a recombinant vector containing the gene and a transformant carrying the gene, and processes for producing the enzyme and 2-pyrone-dicarboxylic acid by using the transformant. Use of the transformant can produce &agr;-hydroxy-&ggr;-carboxymuconic acid-&egr;-semialdehyde dehydrogenase in a large amount, thereby permitting industrial production of 2-pyrone-4,6-dicarboxylic acid.
摘要翻译： α-羟基-γ-羧基粘蛋白酸-ε-半醛脱氢酶，编码该酶的基因，含该基因的重组载体和携带该基因的转化体，以及使用该转化体产生该酶和2-吡喃酮二羧酸的方法使用转化体可以大量生成α-羟基-γ-羧基粘蛋白酸-ε-半醛脱氢酶，从而允许工业生产2-吡喃酮-4,6-二羧酸。

5. 发明授权

US06716609B2 Polypeptides having &agr;-hydroxy-&ggr;-carboxymuconic acid-&egr;-semialdehyde dehydrogenase activity 失效
标题翻译：具有α-羟基-γ-羧基粘蛋白酸-ε-半醛脱氢酶活性的多肽
公开(公告)号：US06716609B2
公开(公告)日：2004-04-06
申请号：US09983306
申请日：2001-10-24
申请人： Eiji Masai , Masao Fukuda , Yoshihiro Katayama , Seiji Nishikawa , Yasushi Hotta
发明人： Eiji Masai , Masao Fukuda , Yoshihiro Katayama , Seiji Nishikawa , Yasushi Hotta
IPC分类号： C12P1706
CPC分类号： C12N9/0008 , C12P7/48 , C12P7/50
摘要： &agr;-Hydroxy-&ggr;-carboxymuconic acid-&egr;-semialdehyde dehydrogenase, a gene encoding the enzyme, a recombinant vector containing the gene and a transformant carrying the gene, and processes for producing the enzyme and 2-pyrone-dicarboxylic acid by using the transformant. Use of the transformant can produce &agr;-hydroxy-&ggr;-carboxymuconic acid-&egr;-semialdehyde dehydrogenase in a large amount, thereby permitting industrial production of 2-pyrone-4,6-dicarboxylic acid.
摘要翻译： α-羟基-γ-羧基粘蛋白酸-ε-半醛脱氢酶，编码该酶的基因，含该基因的重组载体和携带该基因的转化体，以及使用该转化体产生该酶和2-吡喃酮二羧酸的方法使用转化体可以大量生成α-羟基-γ-羧甲基纤维素-ε-半醛脱氢酶，从而允许工业生产2-吡喃酮-4,6-二羧酸。

6. 发明授权

US06604343B2 Latitudinal sealing mechanism for bag-packaging machine and a bag packaging machine having the same 失效
公开(公告)号：US06604343B2
公开(公告)日：2003-08-12
申请号：US10060380
申请日：2002-02-01
申请人： Masao Fukuda
发明人： Masao Fukuda
IPC分类号： B65B920
CPC分类号： B29C65/18 , B29C65/305 , B29C65/745 , B29C66/1122 , B29C66/4312 , B29C66/4322 , B29C66/7373 , B29C66/81427 , B29C66/81431 , B29C66/8161 , B29C66/8221 , B29C66/8226 , B29C66/82263 , B29C66/8242 , B29C66/83513 , B29C66/83543 , B29C66/8491 , B29C66/91212 , B29C66/91231 , B29C66/91421 , B29C66/91641 , B29C66/9241 , B29C66/92615 , B29C66/961 , B29L2031/7128 , B65B51/306
摘要： A latitudinal seal mechanism includes seal jaws 78, fixed cams 75, cam followers 76, a pair of partial cams 88, partial cam followers 78a, rotational shafts 80, coupling members 79, and shaft support portions. The seal jaws 78 are heated, and move circularly such that the seal jaws 78 abut on and move away from tubular film. The fixed cams 75 have shapes that correspond to locuses of movement of the seal jaws 78. The cam followers 76 support the seal jaws 78, and move along the fixed cams 75. The rotational shafts 80 move the cam followers 76 relatively about rotational centers of the rotational shafts 80. The coupling members 79 couple the rotational shafts 80 and the cam followers 76. The shaft support portions rotatably support the rotational shafts 80. The partial cams 88 have a shape that corresponds to a locus of movement of the pair of seal jaws 78 when the pair of seal jaws 78 holds the tubular packaging films. The partial cams 88 make the pair of seal jaws 78 press against each other with the partial cam followers 78a therebetween. The partial cam followers 78a are supported by the pair of seal jaws 78. The partial cam followers 78a engage the corresponding partial cams 88 when the pair of seal jaws 78 holds the tubular packaging film therebetween.

7. 发明授权

US6131366A Packaging machine with mechanisms for positioning its former 失效
标题翻译：包装机具有定位其前者的机构
公开(公告)号：US6131366A
公开(公告)日：2000-10-17
申请号：US481827
申请日：2000-01-12
申请人： Masao Fukuda
发明人： Masao Fukuda
IPC分类号： B65B41/10 , B65B9/20 , B65B41/16 , B65B41/18 , B65B59/00 , B65H23/032 , B65B57/04
CPC分类号： B65H23/0326 , B65B41/16 , B65B41/18 , B65B59/00 , B65B9/20 , B65B9/2014 , B65H2801/69
摘要： A packaging machine has a roll supporting device with a support shaft rotatably supporting a film roll which extends in an axial direction, an elongated bag-forming film being wrapped around the film roll, a bag forming device which pulls out the film from the film roll and forms the film into a shape of a bag, a packaging device for filling the bag-shaped film with articles to be packaged and sealing the film to produce a package, a roll displacing mechanism for displacing the roll supporting device in the axial direction, and a roll position controller for controlling the roll displacing mechanism to adjust the position of the roll supporting device. The bag forming device includes a former for bending the film into a tubular form and a former roller for guiding the film to the former. As a former of a different size is installed, depending on the width of the film, the position of the former roller is changed by a former roller discharging mechanism which includes a first mechanism for supporting the former roller and moving it to a plurality of different positions with respect itself and a second mechanism for moving the first mechanism to a plurality of different positions in the same direction.
摘要翻译：一种包装机具有：辊支撑装置，其具有可旋转地支撑沿轴向延伸的膜卷的支撑轴，缠绕在膜卷上的细长袋形成膜;袋形成装置，其从膜卷中拉出膜并将膜形成袋状，将包装物品填充到袋状膜的包装装置中，并密封膜以制造包装;卷轴移位机构，用于使辊支承装置沿轴向移动; 以及卷位置控制器，用于控制辊移动机构以调节辊支撑装置的位置。袋形成装置包括用于将膜弯曲成管状的成形器和用于将膜引导到前者的前辊。作为不同尺寸的前者，根据薄膜的宽度，前辊的位置由前辊排出机构改变，前辊的排出机构包括用于支撑前辊的第一机构并将其移动到多个不同的位置相对于其自身的位置和用于将第一机构沿相同方向移动到多个不同位置的第二机构。

8. 发明授权

US5983610A Poker for packaging machine 失效
标题翻译：扑克包装机
公开(公告)号：US5983610A
公开(公告)日：1999-11-16
申请号：US6599
申请日：1998-01-13
申请人： Masao Fukuda
发明人： Masao Fukuda
IPC分类号： B65B9/20 , B65B9/10 , B65B35/00
CPC分类号： B65B9/20 , B65B2210/10
摘要： A poker is provided to a packaging machine which has a former for bending a film into a tubular form and a chute for guiding articles to be packaged into a bag being made below. The poker includes a driver link which is driven to undergo a reciprocating rotary motion around a fixed axis and a generally L-shaped arm member disposed above and behind the former. A base part of the arm member is rotatably connected with a moving end part of the driver link such that the arm member can undergo a reciprocating rotary motion around a mobile axis of rotation which rotates around the stationary axis of rotation. A connecting mechanism is further provided to coordinate these two rotational motions such that the tip of the arm member distal from its mobile axis of rotation will move along a desired trajectory to reach a desired bottom center part of the chute which is likely to become clogged with the articles dropped thereinto. The connecting mechanism may be formed with a cam-following member attached to a part of the arm member and a cam plate with an elongated opening such that this cam-following member is constrained to move along an arcuate path determined by this elongated opening.
摘要翻译：将一个扑克提供给包装机，该包装机具有用于将薄膜弯曲成管状的成形器，以及用于将要包装的制品引导到下面制成的袋子中的滑槽。该扑克包括被驱动以围绕固定轴线进行往复旋转运动的驱动器连杆和布置在前者上方和后面的大致L形的臂部件。臂构件的基部与驱动器连杆的移动端部可旋转地连接，使得臂构件可以围绕围绕静止旋转轴线旋转的可动旋转轴线进行往复旋转运动。进一步提供连接机构以协调这两个旋转运动，使得远离其移动旋转轴线的臂构件的尖端将沿着期望的轨迹移动以到达滑槽的期望的底部中心部分，其可能被堵塞文章落在了其中。连接机构可以形成有附接到臂构件的一部分的凸轮跟随构件和具有细长开口的凸轮板，使得该凸轮接合构件被限制为沿着由该细长开口确定的弓形路径移动。

9. 发明授权

US5881539A Transverse sealer for a packaging machine 失效
标题翻译：用于包装机的横向封口机
公开(公告)号：US5881539A
公开(公告)日：1999-03-16
申请号：US856105
申请日：1997-05-13
申请人： Masao Fukuda , Yukio Kakita , James Lewis
发明人： Masao Fukuda , Yukio Kakita , James Lewis
IPC分类号： B65B9/20 , B65B9/213 , B65B51/30 , B65B61/24
CPC分类号： B65B9/213 , B65B51/306 , B65B9/2007
摘要： An elongated web of bag-making material (S) is bent into a tubular form by a former (2), transported along a path (A), is filled with articles (W) and sealed by a transverse sealer (10) transversely to its direction of motion. A pair of seal jaws (20) supported by rotary arms (12) are rotated in mutually opposite directions by a power-communicating mechanism (P) which includes a trajectory-forming mechanism (H) such that the seal jaws (20) will each travel on a generally D-shaped trajectory with a linear section along the path (A) of the bag-making material (S). Cramming devices (50) are adjustably attached to the rotary arms (12) and stroke the tubularly shaped bag-making material (S) from both sides in forward-backward direction (X) without substantially closing the bag being formed such that the articles (W) can be more efficiently crammed with empty spaces among them effectively reduced. Stripping rods (42) are attached to the seal jaws (20) for stripping down the articles being dropped into the bag immediately before the transverse sealing and after the cramming by the cramming devices (50) so as to prevent them from becoming caught between the seal jaws (20).
摘要翻译：制袋材料（S）的细长腹板由沿着路径（A）输送的前者（2）弯曲为管状，填充有制品（W），并横向地横向于由横向密封剂（10）密封其运动方向。由旋转臂（12）支撑的一对密封钳口（20）通过包括轨迹形成机构（H）的动力连通机构（P）在相互相反的方向上旋转，使得密封钳口（20）将各自沿着制袋材料（S）的路径（A）沿直线部分在大致D形轨迹上行进。克隆装置（50）可调节地附接到旋转臂（12），并且从前后方向（X）的两侧沿管状形状的制袋材料（S）行进，而基本上不关闭所形成的袋， W）可以更有效地填补空白空间，有效减少。剥离杆（42）附接到密封爪（20），用于剥离在紧靠横向密封之前被落入袋中的物品，并在挤压装置（50）挤压之后，以防止它们被夹在密封钳口（20）。

10. 发明授权

US5481306A Display circuit for displaying an HDTV signal as twelve NTSC signals and for displaying an independent NTSC signal 失效
标题翻译：用于显示HDTV信号作为十二个NTSC信号并显示独立NTSC信号的显示电路
公开(公告)号：US5481306A
公开(公告)日：1996-01-02
申请号：US125139
申请日：1993-09-23
申请人： Hitoshi Senso , Yoshio Arai , Masao Fukuda
发明人： Hitoshi Senso , Yoshio Arai , Masao Fukuda
IPC分类号： H04N9/797 , H04N5/66
CPC分类号： H04N9/7973 , Y10S345/903
摘要： A video signal recording system is provided in which the number of horizontal scanning lines of a high-definition television system video signal is converted to be M times as large as the number of horizontal scanning lines of an ordinary television video signal. The converted video signal is divided into M vertical sections and N horizontal sections so that M.times.N sections of the divided video signal are separately recorded onto M.times.N recording media respectively. In this way, a high-definition television system video signal can be displayed on a plurality of ordinary television receivers without losing the high-definition television system picture quality.
摘要翻译：提供了一种视频信号记录系统，其中高分辨率电视系统视频信号的水平扫描行数被转换为普通电视视频信号的水平扫描行数的M倍。转换的视频信号被分成M个垂直部分和N个水平部分，使得分割的视频信号的M×N个部分分别记录在MxN个记录介质上。以这种方式，可以在多个普通电视接收机上显示高分辨率电视系统视频信号，而不会失去高清晰度电视系统画面质量。

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