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    • 9. 发明授权
    • 2-Phenylalkyl-3-aminoalkyl-4(3H)-quinazolinone compound
    • 2-苯基烷基-3-氨基烷基-4(3H) - 喹唑啉酮化合物
    • US4668682A
    • 1987-05-26
    • US753708
    • 1985-07-10
    • Tetsuo SekiyaMikio TsutsuiDaijiro HoriiAkira Ishibashi
    • Tetsuo SekiyaMikio TsutsuiDaijiro HoriiAkira Ishibashi
    • C07D239/91A61K31/505A61K31/517A61P3/00A61P3/14A61P9/08A61P9/12A61P11/08C07D239/90C07D401/06
    • C07D239/90
    • Disclosed are a 2-phenylalkyl-3-aminoalkyl-4(3H)-quinazolinone compound of Formula (1): ##STR1## wherein, X represents a hydrogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, a phenoxy group, a benzyloxy group, a halogen atom or a hydroxy group; Y represents an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, a benzyloxy group, a halogen atom or a nitro group; R.sup.1 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms; R.sup.2 represents an alkyl group having 1 to 5 carbon atoms or a group of Formula (2) ##STR2## [wherein, Z represents a hydrogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms or a halogen atom; d is an integer of 1 to 3; and l is an integer of 1 to 5]; or R.sup.1 and R.sup.2 represent together with the nitrogen atom to which they are attached, a cyclic amino group of the formula: ##STR3## [wherein, A represents an alkylene group having 2 to 6 carbon atoms or a group of the formula --(CH.sub.2).sub.2 --O--(CH.sub.2).sub.2 --]; a and b are independently an integer of 1 to 3; and n and m are independently an integer of 1 to 5, or a pharmaceutically acceptable acid addition salt thereof, a process for preparing said compound, a composition comprising said compound as an active ingredient and a method of treatment by use of said compound.The compounds of the present invention have calcium antagonistic, vasodilative, and antihypertensive activities.
    • 公开了式(1)的2-苯基烷基-3-氨基烷基-4(3H) - 喹唑啉酮化合物:其中X表示氢原子,具有1至5个碳原子的烷基,具有1个 至5个碳原子,苯氧基,苄氧基,卤原子或羟基; Y表示碳原子数1〜5的烷基,碳原子数1〜5的烷氧基,苄氧基,卤素原子或硝基。 R1表示氢原子或碳原子数1〜5的烷基。 R 2表示碳原子数1〜5的烷基或式(2)的基团[其中,Z表示氢原子,碳原子数1〜5的烷基,碳原子数1〜5的烷氧基 或卤素原子; d为1〜3的整数, l为1〜5的整数]。 或者R 1和R 2与它们所连接的氮原子一起表示下式的环状氨基:其中A表示碳原子数为2〜6的亚烷基或式 - (CH 2 )2-O-(CH 2)2 - ]; a和b独立地为1〜3的整数; n和m独立地为1〜5的整数,或其药学上可接受的酸加成盐,制备所述化合物的方法,包含所述化合物作为活性成分的组合物和使用所述化合物的方法。 本发明的化合物具有钙拮抗,血管扩张和抗高血压活性。
    • 10. 发明授权
    • Energy converter
    • 能量转换器
    • US08575878B2
    • 2013-11-05
    • US13131306
    • 2009-11-26
    • Tetsuo SekiyaKiyotsugu Narita
    • Tetsuo SekiyaKiyotsugu Narita
    • H02P1/00
    • H02P25/04H02K5/1732H02K15/125H02K16/02H02K17/02H02K2201/03H05B6/108H05B6/109
    • An energy converter includes a magnetism generation mechanism unit that generates a magnetic field when connected to an AC electrical power source, and a rotating mechanism unit having a single turn coil array member in which a plurality of single turn coils is disposed at a predetermined interval and a soft magnetic metal plate disposed on a side of the single turn coil array member opposite to the magnetism generation mechanism unit. The rotating mechanism unit is structured such that the single turn coil array member faces the magnetism generation mechanism unit across a predetermined magnetic gap and rotary driven by the magnetic field. Here, a drive signal period of the electrical power source is a period that maximizes an eddy current generated in the soft magnetic metal plate.
    • 能量转换器包括:当连接到AC电源时产生磁场的磁力发生机构单元和具有单个匝数组件的旋转机构单元,其中多个单匝线圈以预定间隔设置, 设置在与该磁性发生机构单元相对的单匝线圈阵列构件侧的软磁金属板。 旋转机构单元被构造成使得单匝线圈阵列构件跨过预定的磁隙面对磁性发生机构单元并且由磁场驱动旋转。 这里,电源的驱动信号周期是使软磁金属板中产生的涡电流最大化的期间。