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1. 发明授权

US5721808A Method for the composition of noise-resistant hidden markov models for speech recognition and speech recognizer using the same 失效
标题翻译：用于语音识别和语音识别器的噪声抵抗隐马尔可夫模型的组合方法
公开(公告)号：US5721808A
公开(公告)日：1998-02-24
申请号：US610614
申请日：1996-03-04
申请人： Yasuhiro Minami , Tomoko Matsui , Sadaoki Furui
发明人： Yasuhiro Minami , Tomoko Matsui , Sadaoki Furui
IPC分类号： G10L15/14 , G10L15/20 , G10L5/06
CPC分类号： G10L15/20 , G10L15/144
摘要： Noise-resistant speech HMMs are composed by: recording noise in the environment of utterance (S.sub.1); preparing HMMs of the noise (S.sub.2); transforming the output probability distribution of each of the noise HMMs and speech HMMs prepared from speech unaffected by noise and multiplicative distortion to a linear spectral domain (S.sub.31); multiplying the speech HMM distribution in the linear spectral domain by a multiplicative distortion W that is an unknown variable (S.sub.321); convoluting the multiplied value and the noise HMM distribution in the linear spectral domain (S.sub.322); inversely transforming the convoluted value to the original domain of the speech HMM (S.sub.33) to compose incomplete noise-resistant speech HMMs each containing multiplicative distortion as an unknown variable (S.sub.3); calculating the likelihoods of the incomplete noise-resistant speech HMMs for input speech and estimating the multiplicative distortion of that one of the incomplete noise-resistant HMMs which has the maximum likelihood (S.sub.4); and substituting the estimated value into the incomplete noise-resistant speech HMMs (S.sub.5).
摘要翻译：抗噪声语音HMM由以下内容组成：在语音环境中记录噪声（S1）; 准备HMM的噪声（S2）; 将由不受噪声和乘法失真影响的语音准备的每个噪声HMM和语音HMM的输出概率分布变换为线性频域（S31）; 将线性频域中的语音HMM分布乘以作为未知变量的乘法失真W（S321）; 在线性谱域中卷积乘法值和噪声HMM分布（S322）; 将卷积值逆向变换为语音HMM的原始域（S33），以构成每个包含乘法失真的不完整的抗噪声语音HMM作为未知变量（S3）; 计算用于输入语音的不完整的抗噪声语音HMM的可能性，并估计具有最大似然性的不完全抗噪声HMM中的一个的乘法失真（S4）; 并将估计值代入不完整的抗噪声语音HMM（S5）。

2. 发明授权

US5835890A Method for speaker adaptation of speech models recognition scheme using the method and recording medium having the speech recognition method recorded thereon 失效
标题翻译：使用该方法的语音模型识别方案的讲话者适应方法和其上记录有语音识别方法的记录介质
公开(公告)号：US5835890A
公开(公告)日：1998-11-10
申请号：US835421
申请日：1997-04-09
申请人： Tomoko Matsui , Sadaoki Furui
发明人： Tomoko Matsui , Sadaoki Furui
IPC分类号： G10L15/065 , G10L7/08
CPC分类号： G10L15/065
摘要： In a speaker adaptation method for speech models, input speech is transformed to a feature parameter sequence like a cepstral sequence, and N model sequences of maximum likelihood for the feature parameter sequence are extracted from speaker-independent speech HMMs by an N-best hypothesis extraction method. The extracted model sequences are each provisionally adapted to maximize its likelihood for the feature parameter sequence of the input speech while changing the HMM parameters of each sequence, and that one of the provisionally adapted model sequences which has the maximum likelihood for the feature parameter sequence of the input speech is selected and speech models of the selected sequence are provided as adapted HMMs of the speaker to be recognized.
摘要翻译：在用于语音模型的说话人适应方法中，输入语音被转换成诸如倒谱序列的特征参数序列，并且通过N最佳假设提取从与说话者无关的语音HMM中提取特征参数序列的最大似然度的N个模型序列方法。提取的模型序列每个临时适合于在改变每个序列的HMM参数的同时最大化其输入语音的特征参数序列的可能性，并且对于特征参数序列具有最大可能性的临时适配模型序列之一选择输入语音，并且提供所选序列的语音模型作为待识别的说话者的适应HMM。

3. 发明申请

US20140147893A1 ALPHA AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 有权
标题翻译： ALPHA AMYLASE变体和编码它的多核苷酸
公开(公告)号：US20140147893A1
公开(公告)日：2014-05-29
申请号：US14131148
申请日：2012-07-06
申请人： Tomoko Matsui , Aki Tomiki , Guillermo Coward-Kelly
发明人： Tomoko Matsui , Aki Tomiki , Guillermo Coward-Kelly
IPC分类号： C12N9/30 , C12P19/20 , C12P19/02
CPC分类号： C12N9/2417 , C07K2319/20 , C12N9/242 , C12P7/06 , C12P7/10 , C12P19/02 , C12P19/14 , C12P19/20 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to variants of alpha amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译：本发明涉及α淀粉酶的变体。本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

4. 发明申请

US20130344573A1 Signal Peptide for Producing a Polypeptide 有权
公开(公告)号：US20130344573A1
公开(公告)日：2013-12-26
申请号：US13968958
申请日：2013-08-16
申请人： Tomoko Matsui , Henriette Draborg , Steffen Danielsen
发明人： Tomoko Matsui , Henriette Draborg , Steffen Danielsen
IPC分类号： C12N9/64 , C12N9/16 , C12N9/42
CPC分类号： C12N9/6472 , C07K14/37 , C12N9/16 , C12N9/2437 , C12N9/6424 , C12N15/625
摘要： The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising the nuclei acid construct.

5. 发明授权

US08263381B2 Enzymes for starch processing 有权
标题翻译：淀粉加工酶
公开(公告)号：US08263381B2
公开(公告)日：2012-09-11
申请号：US12859866
申请日：2010-08-20
申请人： Hiroaki Udagawa , Rikako Taira , Shinobu Takagi , Carsten Hjort , Anders Vikso-Nielsen , Eric Allain , Shiro Fukuyama , Tomoko Matsui
发明人： Hiroaki Udagawa , Rikako Taira , Shinobu Takagi , Carsten Hjort , Anders Vikso-Nielsen , Eric Allain , Shiro Fukuyama , Tomoko Matsui
IPC分类号： C12N9/26 , C12N9/24 , A21D2/00 , C07H21/04
CPC分类号： C12P19/14 , C07K2319/00 , C12N9/2408 , C12N9/2411 , C12N9/2414 , C12N9/242 , C12N9/2425 , C12N9/2428 , C12P7/06 , C12P19/02 , C12P19/16 , C12P19/22 , C13K11/00 , Y02E50/17
摘要： The present invention relates to a hybrid enzyme comprising carbohydrate-binding module amino acid sequence and a fungal alpha-amylase amino acid sequence and to a variant of a fungal wild type enzyme comprising a carbohydrate-binding module and an alpha-amylase catalytic module. The invention also relates to the use of the hybrid enzyme or the variant in starch liquefaction.
摘要翻译：本发明涉及包含碳水化合物结合模块氨基酸序列和真菌α-淀粉酶氨基酸序列的杂合酶以及包含碳水化合物结合模块和α-淀粉酶催化模块的真菌野生型酶的变体。本发明还涉及混合酶或变体在淀粉液化中的用途。

6. 发明授权

US07871806B2 Asparaginases 有权
标题翻译：天冬酰胺酶
公开(公告)号：US07871806B2
公开(公告)日：2011-01-18
申请号：US12782150
申请日：2010-05-18
申请人： Tomoko Matsui , Esben Peter Friis , Akihiko Yamagishi
发明人： Tomoko Matsui , Esben Peter Friis , Akihiko Yamagishi
IPC分类号： C12N9/82 , C12N1/20 , C12N1/00 , C12N15/00 , C07H21/04
CPC分类号： C12N9/82 , A23L5/25 , A23L19/18 , C12Y305/01001
摘要： The invention relates to new asparaginases having improved properties, preferably improved thermotolerance, such as improved activity at high temperatures and/or improved thermostability. The invention also relates to DNA sequences encoding such improved asparaginases, their production in a recombinant host cell, as well as methods of using the asparaginases, in particular for reduction of acrylamide in foods. The invention furthermore relates to methods of generating and preparing asparaginase variants having improved properties.
摘要翻译：本发明涉及具有改进性能的新型天冬酰胺酶，优选改进的耐热性，例如在高温下改善的活性和/或改善的热稳定性。本发明还涉及编码这种改良天冬酰胺酶的DNA序列，其在重组宿主细胞中的产生，以及使用天冬酰胺酶，特别是用于还原食品中丙烯酰胺的方法。本发明还涉及产生和制备具有改进性质的天冬酰胺酶变体的方法。

7. 发明申请

US20090191590A1 Signal Peptide for Producing a Polypeptide 有权
标题翻译：用于产生多肽的信号肽
公开(公告)号：US20090191590A1
公开(公告)日：2009-07-30
申请号：US12415174
申请日：2009-03-31
申请人： Tomoko Matsui , Henriette Draborg , Steffen Danielsen
发明人： Tomoko Matsui , Henriette Draborg , Steffen Danielsen
IPC分类号： C12P21/06 , C07H21/04 , C12N15/63
CPC分类号： C12N9/6472 , C07K14/37 , C12N9/16 , C12N9/2437 , C12N9/6424 , C12N15/625
摘要： The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising the nuclei acid construct.
摘要翻译：本发明涉及包含使用信号肽的多肽的制备方法，其包含编码信号肽的第一核苷酸序列的核酸构建体和编码第一核苷酸序列异源的多肽的第二核苷酸序列。此外，它还涉及包含核酸构建体的表达载体和宿主细胞。

8. 发明申请

US20060148054A1 Enzymes for starch processing 审中-公开
标题翻译：淀粉加工酶
公开(公告)号：US20060148054A1
公开(公告)日：2006-07-06
申请号：US11316535
申请日：2005-12-22
申请人： Shiro Fukuyama , Tomoko Matsui , Chee Soong , Eric Allain , Anders Nielsen , Hiroaki Udagawa , Ye Liu , Junxin Duan , Wenping Wu , Lene Andersen
发明人： Shiro Fukuyama , Tomoko Matsui , Chee Soong , Eric Allain , Anders Nielsen , Hiroaki Udagawa , Ye Liu , Junxin Duan , Wenping Wu , Lene Andersen
IPC分类号： C07H21/04 , C12P21/06 , C12P7/06 , C12N9/32 , C12N15/74 , C12N1/18
CPC分类号： C12P19/14 , C07K2319/00 , C12N9/242 , C12N9/2428 , C12P7/06 , C12P19/02 , C12Y302/01001 , C12Y302/01003 , Y02E50/17
摘要： The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and,an alpha-amylase amino acid sequence as well as to the application of such polypeptides.
摘要翻译：本发明涉及包含碳水化合物结合组件氨基酸序列和α-淀粉酶氨基酸序列以及这些多肽的应用的多肽。

9. 发明申请

US20060003414A1 Signal peptide for producing a polypeptide 有权
公开(公告)号：US20060003414A1
公开(公告)日：2006-01-05
申请号：US11152811
申请日：2005-06-14
申请人： Tomoko Matsui , Henriette Draborg , Steffen Danielsen
发明人： Tomoko Matsui , Henriette Draborg , Steffen Danielsen
IPC分类号： C12P21/06 , C07H21/04 , C12N9/02 , C12N9/10 , C12N9/16 , C12N9/20 , C12N1/16 , C12N9/24 , C12N15/74
CPC分类号： C12N9/6472 , C07K14/37 , C12N9/16 , C12N9/2437 , C12N9/6424 , C12N15/625
摘要： The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising the nuclei acid construct.

10. 发明申请

US20050031312A1 Method and apparatus for signal reproduction 审中-公开
标题翻译：用于信号再现的方法和装置
公开(公告)号：US20050031312A1
公开(公告)日：2005-02-10
申请号：US10895377
申请日：2004-07-21
申请人： Tomoko Matsui , Ryouji Yamaguchi , Tadashi Shibata
发明人： Tomoko Matsui , Ryouji Yamaguchi , Tadashi Shibata
IPC分类号： G11B20/10 , H04N5/781 , H04N5/85 , H04N5/907 , H04N9/804 , H04N9/806 , H04N5/76
CPC分类号： H04N9/8063 , G11B20/10 , G11B2020/1062 , G11B2020/10694 , G11B2020/10814 , H04N5/781 , H04N5/85 , H04N5/907 , H04N9/8042 , H04N9/8047
摘要： This invention provides a method and apparatus for signal reproduction that can simultaneously reproduce N (N≧2) signals which are previously multiplexed, and simultaneously reproduce N independent signals. This apparatus selectively inputs the independent N coded signals in time division, adds the corresponding stream information to the selected input signal among N kinds of stream information for identifying the input signals, detects the stream information from the respective input signal, decodes the respective input signal by a decoding method corresponding to the respective input signal, which is decided based on the detected stream information, and outputs the decoded signal.
摘要翻译：本发明提供一种用于信号再现的方法和装置，其可以同时再现先前多路复用的N（N> = 2）个信号，同时再现N个独立信号。该装置以时分方式选择性地输入独立的N个编码信号，将N个用于识别输入信号的流信息中的所选输入信号相加的流信息相加，从相应的输入信号检测流信息，解码各输入信号通过与基于检测到的流信息决定的各个输入信号对应的解码方式，输出解码信号。

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