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1. 发明授权

US09617538B2 Heptamer-type small guide nucleic acids inducing apoptosis of human leukemia cells 有权
公开(公告)号：US09617538B2
公开(公告)日：2017-04-11
申请号：US14241580
申请日：2012-08-24
申请人： Masayuki Nashimoto , Masuhiro Takahashi , Miwako Narita , Tetsuo Yoshida , Tatsuya Miyazawa
发明人： Masayuki Nashimoto , Masuhiro Takahashi , Miwako Narita , Tetsuo Yoshida , Tatsuya Miyazawa
IPC分类号： C07H21/02 , C12N15/113 , A61K31/7105
CPC分类号： C12N15/113 , A61K31/7105 , C12N2310/12
摘要： There is provided a heptamer-type small guide nucleic acid that comprises any of the 7-base sequences of SEQ ID NOS: 1 to 15, and induces apoptosis of human leukemia cells. A leukemia therapeutic agent containing the heptamer-type small guide nucleic acid as an active ingredient is also provided. The novel heptamer-type sg nucleic acid can induce apoptosis of human leukemia cells.

2. 发明授权

US09405048B2 Reflective polarizing film, and optical member for liquid crystal display device, and liquid crystal display device formed from same 有权
标题翻译：反射型偏振片，液晶显示装置用光学构件，以及由其构成的液晶显示装置
公开(公告)号：US09405048B2
公开(公告)日：2016-08-02
申请号：US14122799
申请日：2012-06-14
申请人： Taro Oya , Mitsumasa Ono , Tetsuo Yoshida
发明人： Taro Oya , Mitsumasa Ono , Tetsuo Yoshida
IPC分类号： C09K19/00 , G02B5/30 , G02F1/1335
CPC分类号： G02B5/3025 , G02B5/305 , G02F1/133536 , G02F2001/133545 , Y10T428/10 , Y10T428/1036
摘要： A multilayered reflective polarizing film is provided that has high polarization performance comparable to that of an absorption-type polarizing plate, and is preferred as a polarizing plate attached to a liquid crystal cell. An optical member for liquid crystal display devices, and a liquid crystal display device formed from such a multilayered reflective polarizing film are also provided. Specifically, the reflective polarizing film includes a uniaxially stretched multilayered film in which a specific aromatic polyester containing (alkylenedioxy)di-2-naphthoic acid as a part of dicarboxylic acid components is used as a first layer, and an optically isotropic polyester having an average refractive index of 1.50 to 1.60 is used as a second layer, and that has a predetermined refractive index difference between the layers. The reflective polarizing film has an angle of orientation of 2 degrees or less.
摘要翻译：提供了具有与吸收式偏振片相当的高极化性能的多层反射偏振膜，并且优选作为连接到液晶单元的偏振片。还提供了一种用于液晶显示装置的光学构件和由这种多层反射偏光膜形成的液晶显示装置。具体地，反射偏振膜包括单轴拉伸多层膜，其中使用含有作为二羧酸成分的一部分的（亚烷基二氧基）二-2-萘甲酸的特定芳族聚酯作为第一层，和具有平均值的光学各向同性聚酯折射率为1.50〜1.60用作第二层，并且在层之间具有预定的折射率差。反射偏振膜的取向角为2度以下。

3. 发明申请

US20120207818A1 COMPOSITION FOR SUPPRESSING EXPRESSION OF TARGET GENE 审中-公开
标题翻译：用于抑制目标基因表达的组合物
公开(公告)号：US20120207818A1
公开(公告)日：2012-08-16
申请号：US13348959
申请日：2012-01-12
申请人： Fumikazu SHINOHARA , Tetsuo Yoshida , Hiroko Sugishita , Tomoyuki Naoi , Toshihiko Ishii , Junichi Enokizono
发明人： Fumikazu SHINOHARA , Tetsuo Yoshida , Hiroko Sugishita , Tomoyuki Naoi , Toshihiko Ishii , Junichi Enokizono
IPC分类号： A61K9/127 , A61P35/00 , A61P29/00 , A61K31/7088
CPC分类号： A61K31/713 , A61K9/0019 , A61K9/10 , A61K9/1271 , C12N15/1135 , C12N2310/11 , C12N2320/32 , C12N2310/321 , C12N2310/3521
摘要： The present invention provides a composition that comprises a liposome encapsulating a double-stranded nucleic acid molecule, wherein the antisense strand is a polynucleotide of 17 to 30 bases in which a sequence is complementary to the sequence of the 17 contiguous bases of a target gene's mRNA, the sense strand is a polynucleotide of 17 to 30 bases that contains a base sequence complementary to the base sequence of bases 1 to 17 in the 5′-end to 3′-end direction of the antisense strand, and a particular amount of the sugars binding to certain bases of the antisense strand and the sense strand are deoxyribose, or ribose whose hydroxyl group at the 2′ position is substituted by a modifying group, and wherein the liposome contains a lipid bilayer membrane whose constituent component is a lipid conjugate, a fatty acid conjugate or an aliphatic hydrocarbon conjugate of a water-soluble substance.
摘要翻译：本发明提供一种包含包封双链核酸分子的脂质体的组合物，其中，所述反义链是17〜30个碱基的多核苷酸，其中序列与靶基因的mRNA的17个连续碱基的序列互补有义链是17〜30个碱基的多核苷酸，其含有与反义链的5'端至3'-端方向的碱基1至17的碱基序列互补的碱基序列，特定量的与反义链和有义链的某些碱基结合的糖是脱氧核糖或其2'位的羟基被修饰基团取代的核糖，并且其中所述脂质体含有脂质双层膜，其构成成分是脂质缀合物，脂肪酸结合物或水溶性物质的脂族烃共轭物。

4. 发明授权

US08047341B2 Cylinder apparatus 有权
标题翻译：气缸装置
公开(公告)号：US08047341B2
公开(公告)日：2011-11-01
申请号：US12219425
申请日：2008-07-22
申请人： Satsuki Yamamoto , Yusuke Maegawa , Tetsuo Yoshida
发明人： Satsuki Yamamoto , Yusuke Maegawa , Tetsuo Yoshida
IPC分类号： F16F9/32
CPC分类号： F16F9/56
摘要： A hydraulic shock absorber enables its piston rod to be locked near its minimum length position and allows the locked condition to be visually confirmed easily. A cap member is secured to a distal end portion of a piston rod extending from a cylinder part, and a dust cover is secured to the cap member. A lock member is secured to an end of the cylinder part from which the piston rod extends to the outside. The lock member is cut and bent upward to form engaging portions. The cap member is cut and bent downward to form engaging pieces and windows. With the piston rod contracted to near its minimum length position, the cap member is rotated to engage the engaging portions and the engaging pieces with each other, thereby locking the piston rod. The engaged condition of the engaging portions and the engaging pieces can be visually confirmed through the windows.
摘要翻译：液压减震器使其活塞杆在其最小长度位置附近锁定，并允许容易地目视确认锁定状态。帽构件固定到从气缸部分延伸的活塞杆的远端部分，并且防尘盖固定到盖构件。锁定构件固定到活塞杆从其延伸到外部的气缸部分的端部。锁定构件被向上切割并弯曲以形成接合部分。盖构件被切割并向下弯曲以形成接合件和窗。随着活塞杆收缩到其最小长度位置附近，盖构件被旋转以使接合部分和接合件彼此接合，从而锁定活塞杆。可以通过窗户目视确认接合部分和接合件的接合状态。

5. 发明申请

US20100209722A1 BIAXIALLY ORIENTED FILM FOR ELECTRIC INSULATION 审中-公开
标题翻译：双向电导率电绝缘膜
公开(公告)号：US20100209722A1
公开(公告)日：2010-08-19
申请号：US12602964
申请日：2008-05-28
申请人： Tetsuo Yoshida
发明人： Tetsuo Yoshida
IPC分类号： B32B15/09 , B32B27/36
CPC分类号： B32B15/08 , B29C55/143 , B29K2067/00 , B29K2105/0044 , B29K2995/0007 , C08J5/18 , C08J2367/02 , H01G4/18 , Y10T428/31681 , Y10T428/31786
摘要： A biaxially oriented polyester film which has high dielectric strength at a temperature range from room temperature to a high temperature, maintains high dielectric strength even after it is heated for a long time and is suitable for electric insulation application.The film comprises at least one layer made of a polyester, the polyester of the at least one layer contains a titanium compound as a catalyst and a radical scavenging stabilizer, the content of the radical scavenging stabilizer is 1,000 to 50,000 ppm based on the weight of the polyester, and the amount of the radical scavenging stabilizer chemically bonded to the polyester does not exceed 200 ppm.
摘要翻译：在从室温到高温的温度范围内具有高介电强度的双轴取向聚酯膜，即使在长时间加热之后也保持高介电强度，并且适用于电绝缘应用。该薄膜包括至少一层由聚酯制成的层，该至少一层的聚酯含有钛化合物作为催化剂和自由基清除稳定剂，自由基清除稳定剂的含量以重量计为1000-50,000ppm 聚酯，与聚酯化学键合的自由基清除稳定剂的量不超过200ppm。

6. 发明申请

US20100062239A1 BIAXIALLY ORIENTED FILM FOR ELECTRICAL INSULATION, FILM CAPACITOR CONSTITUTING MEMBER FORMED OF THE SAME, AND FILM CAPACITOR INCLUDING SAME 审中-公开
标题翻译：用于电绝缘的双向导向薄膜，其形成的薄膜电容器和包括其的薄膜电容器
公开(公告)号：US20100062239A1
公开(公告)日：2010-03-11
申请号：US12525252
申请日：2008-01-30
申请人： Tetsuo Yoshida
发明人： Tetsuo Yoshida
IPC分类号： H01B3/30
CPC分类号： B29C55/12 , B29K2067/00 , B29K2105/162 , B32B15/08 , B32B27/18 , B32B27/302 , B32B27/32 , B32B27/36 , B32B2264/108 , B32B2307/206 , B32B2307/518 , B32B2307/704 , B32B2457/08 , B32B2605/00 , C08J5/18 , C08J2367/02 , C08K3/045 , H01B3/423 , H01G4/18 , H01G4/206 , H05K1/0373 , H05K1/0393 , H05K1/162 , H05K2201/0323 , Y10T428/25 , C08L67/02
摘要： An object of the present invention is to provide a biaxially oriented film for electrical insulation that has excellent withstand voltage characteristics over a temperature range from room temperature to higher temperatures. The film excels in withstand voltage characteristics and processability by inclusion of fullerene in a crystalline thermoplastic resin film.
摘要翻译：本发明的目的是提供一种用于电绝缘的双轴取向膜，其在室温至较高温度的温度范围内具有优异的耐电压特性。该膜通过在结晶性热塑性树脂膜中包含富勒烯而具有优异的耐电压特性和加工性。

7. 发明申请

US20060263592A1 Polyester film 有权
标题翻译：聚酯薄膜
公开(公告)号：US20060263592A1
公开(公告)日：2006-11-23
申请号：US10571094
申请日：2004-05-27
申请人： Hiroshi Kusume , Atsushi Oyamatsu , Tetsuo Yoshida
发明人： Hiroshi Kusume , Atsushi Oyamatsu , Tetsuo Yoshida
IPC分类号： B32B5/16
CPC分类号： G02B5/0841 , B32B27/08 , B32B27/18 , B32B27/20 , B32B27/36 , B32B2250/244 , B32B2264/02 , B32B2264/102 , B32B2264/104 , B32B2307/308 , B32B2307/416 , B32B2307/71 , B32B2307/734 , B32B2457/20 , B32B2509/00 , C08J5/18 , C08J2367/02 , C08K3/013 , Y10T428/24942 , Y10T428/25 , Y10T428/254 , Y10T428/256 , Y10T428/257 , Y10T428/258 , Y10T428/259 , Y10T428/26 , Y10T428/266 , Y10T428/268 , Y10T428/269 , Y10T428/31786
摘要： There is provided a white polyester film which retains practically satisfactory reflectivity with respect to the visible light range, can undergo stable film production even when inorganic fine particles are added in high concentration and is stable against a dimensional change caused by heat generated from a light source. The polyester film is a polyester film which comprises a composition comprising a copolyester and 30 to 50 wt % of inorganic fine particles based on the composition, shows a thermal shrinkage at 85° C. in longitudinal and transverse directions of not higher than 0.7% and a thermal shrinkage at 150° C. in the longitudinal and transverse directions of not higher than 5.0%, and shows an average reflectance at a wavelength of 400 to 700 nm of not lower than 90%.
摘要翻译：提供了白色聚酯膜，其相对于可见光范围保持实际上令人满意的反射率，即使当高浓度添加无机细颗粒并且对于由光源产生的热引起的尺寸变化是稳定的，也可以进行稳定的膜生产。聚酯膜是包含基于该组成的包含共聚酯和30至50重量％的无机细颗粒的组合物的聚酯膜，显示在纵向和横向上85℃下的热收缩率不高于0.7％，并且在纵向和横向的150℃下的热收缩率不高于5.0％，并且在400至700nm的波长下的平均反射率不低于90％。

8. 发明申请

US20050269292A1 Plasma processing apparatus and method, and electrode plate for plasma processing apparatus 有权
标题翻译：等离子体处理装置和方法以及等离子体处理装置的电极板
公开(公告)号：US20050269292A1
公开(公告)日：2005-12-08
申请号：US11137492
申请日：2005-05-26
申请人： Akira Koshiishi , Jun Hirose , Masahiro Ogasawara , Taichi Hirano , Hiromitsu Sasaki , Tetsuo Yoshida , Michishige Saito , Hiroyuki Ishihara , Jun Ooyabu , Kohji Numata
发明人： Akira Koshiishi , Jun Hirose , Masahiro Ogasawara , Taichi Hirano , Hiromitsu Sasaki , Tetsuo Yoshida , Michishige Saito , Hiroyuki Ishihara , Jun Ooyabu , Kohji Numata
IPC分类号： H05H1/46 , B01J3/00 , B01J19/08 , C23F1/00 , H01J37/32 , H01L21/304 , H01L21/306 , H01L21/3065
CPC分类号： H01J37/32449 , H01J37/32027 , H01J37/32091 , H01J37/32174 , H01J37/32541 , H01J37/3255 , H01J37/32587
摘要： A plasma processing apparatus includes a process container configured to have a vacuum atmosphere therein. A first upper electrode is disposed to have a ring shape and to face a target substrate placed within the process container. A second upper electrode is disposed radially inside the first upper electrode and electrically insulated therefrom. A first electric feeder is configured to supply a first RF output from a first RF power supply to the first upper electrode at a first power value. A second electric feeder branches from the first electric feeder and is configured to supply the first RF output from the first RF power supply to the second upper electrode at a second power value smaller than the first power value.
摘要翻译：一种等离子体处理装置，包括被配置为在其中具有真空气氛的处理容器。第一上电极被设置成具有环形并且面对放置在处理容器内的目标衬底。第二上电极径向设置在第一上电极内并与其电绝缘。第一馈电器被配置为以第一功率值将第一RF电源的第一RF输出提供给第一上电极。第二馈电器从第一馈电器分支并且被配置为以小于第一功率值的第二功率值将第一RF电源的第一RF输出提供给第二上电极。

9. 发明申请

US20050137138A1 E2F activity-inhibiting compound 审中-公开
标题翻译： E2F活性抑制化合物
公开(公告)号：US20050137138A1
公开(公告)日：2005-06-23
申请号：US10752505
申请日：2004-01-08
申请人： Kenji Shibata , Motoo Yamasaki , Tetsuo Yoshida , Tamio Mizukami
发明人： Kenji Shibata , Motoo Yamasaki , Tetsuo Yoshida , Tamio Mizukami
IPC分类号： A61K38/00 , C07K14/47 , A61K38/08 , C07K7/06
CPC分类号： C07K14/4705 , A61K38/00
摘要： E2F-inhibiting compounds are represented by the general formula: R1-A-R2 wherein A represents a peptide sequence comprising a partial amino acid sequence having at least 12 continuous residues in the sequence of the dimerization region or DNA binding region of the E2F family), which are useful as a therapeutic agent of diseases such as tumor and arteriosclerosis, for which abnormal cellular growth is responsible.
摘要翻译： E2F抑制化合物由以下通式表示：其中A表示包含部分氨基酸序列的肽序列，所述部分氨基酸序列具有至少12个连续残基 E2F家族的二聚化区域或DNA结合区域的序列），其可用作肿瘤和动脉硬化疾病的治疗剂，异常细胞生长负责。

10. 发明授权

US5681155A Scroll type compressor having an elastic body in the driven crank mechanism 失效
标题翻译：涡旋式压缩机在从动曲柄机构中具有弹性体
公开(公告)号：US5681155A
公开(公告)日：1997-10-28
申请号：US610576
申请日：1996-03-08
申请人： Shigeru Hisanaga , Tsuyoshi Takemoto , Shigeki Iwanami , Haruhisa Shibata , Takeshi Sakai , Masafumi Nakashima , Mikio Matsuda , Tatsuhiko Fukanuma , Tetsuo Yoshida , Yasushi Watanabe , Shinsuke Aso
发明人： Shigeru Hisanaga , Tsuyoshi Takemoto , Shigeki Iwanami , Haruhisa Shibata , Takeshi Sakai , Masafumi Nakashima , Mikio Matsuda , Tatsuhiko Fukanuma , Tetsuo Yoshida , Yasushi Watanabe , Shinsuke Aso
IPC分类号： F04C29/06 , F04C18/02 , F04C28/06 , F04C29/00 , F04C18/04 , F04C29/02
CPC分类号： F04C29/0057
摘要： A scroll type compressor using a crank mechanism having enough freedom so that an amount of eccentricity of the movable scroll member becomes variable. An elastic body is inserted between the facing surfaces striking each other in the inside of the crank mechanism so as to prevent generation of a noise due to the collision of the parts when starting up or shutting down the compressor.
摘要翻译：一种使用具有足够自由度的曲柄机构的涡旋式压缩机，使得可动涡旋件的偏心量变得可变。弹性体插入在曲柄机构的内部彼此相对的相对表面之间，以防止在启动或关闭压缩机时由于部件碰撞而产生噪音。

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