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1. 发明申请

US20080289052A1 Method of Constructing Animal Having Cancer Cells Transplanted Thereinto 审中-公开
标题翻译：构建具有移植癌细胞的动物的方法
公开(公告)号：US20080289052A1
公开(公告)日：2008-11-20
申请号：US10591612
申请日：2005-03-04
申请人： Teruo Okano , Akihiko Kikuchi , Masayuki Yamato , Akira Masuda
发明人： Teruo Okano , Akihiko Kikuchi , Masayuki Yamato , Akira Masuda
IPC分类号： G01N33/15 , A01K67/027
CPC分类号： A01K67/0271 , A01K2227/105 , A01K2267/0331 , A61K49/0008 , C12N5/0693
摘要： A cell culture support is first prepared that is coated on a surface with a polymer the hydration force of which changes in a temperature range of 0-80° C.; cancer cells are then cultivated on the support in a temperature region where the polymer has weak hydration force; thereafter, the culture solution is adjusted to a temperature at which the polymer has a stronger hydration force, whereby the cultured cancer cells are detached; the detached cancer cells are then transplanted to a specified site of an animal on which transplantation is to be performed; this method is an efficient way of cancer cells transplantation.
摘要翻译：首先制备细胞培养载体，其涂覆在表面上，其水合力在0-80℃的温度范围内变化; 然后将癌细胞在聚合物具有弱水合力的温度区域中在载体上培养; 此后，将培养液调整为聚合物具有更强的水合力的温度，由此分离培养的癌细胞。然后将分离的癌细胞移植到要进行移植的动物的特定部位; 这种方法是癌细胞移植的有效途径。

2. 发明申请

US20090012252A1 Polymeric Derivative of Cytidine Metabolic Antagonist 有权
标题翻译：胞苷代谢拮抗剂的聚合衍生物
公开(公告)号：US20090012252A1
公开(公告)日：2009-01-08
申请号：US11919912
申请日：2006-04-27
申请人： Akira Masuda , Takeshi Onda , Hiroko Mashiba , Keiichirou Yamamoto , Kazutoshi Takashio
发明人： Akira Masuda , Takeshi Onda , Hiroko Mashiba , Keiichirou Yamamoto , Kazutoshi Takashio
IPC分类号： C08G83/00
CPC分类号： C08G73/0233 , A61K47/60 , A61K47/645 , C08G65/329 , C08G65/3332 , C08G73/028
摘要： [PROBLEMS] To provide a derivative of a cytidine metabolic antagonist which can exert a high therapeutic effect at a low dose.[MEANS FOR SOLVING PROBLEMS] A polymeric derivative of a cytidine metabolic antagonist which comprises a polymeric compound having a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a cytidine metabolic antagonist, which has such a structure that the carboxyl group in the side chain of the polymeric compound and an amino group in the cytidine metabolic antagonist are bound together to form an amide bond.
摘要翻译： [问题]提供可以以低剂量发挥高治疗效果的胞苷代谢拮抗剂的衍生物。解决问题的手段胞苷代谢拮抗剂的聚合衍生物包含具有聚乙二醇部分和侧链中具有羧基的聚合物部分和胞苷代谢拮抗剂的聚合物，其具有以下结构：羧基聚合化合物的侧链基团和胞苷代谢拮抗剂中的氨基结合在一起形成酰胺键。

3. 发明授权

US06915105B2 Learning system, learning apparatus, and learning method 失效
标题翻译：学习系统，学习机器和学习方法
公开(公告)号：US06915105B2
公开(公告)日：2005-07-05
申请号：US10224083
申请日：2002-08-19
申请人： Akira Masuda
发明人： Akira Masuda
IPC分类号： G09B5/14 , G06Q10/00 , G06Q10/06 , G06Q10/10 , G06Q30/06 , G06Q50/00 , G06Q50/10 , G06Q50/20 , G09B7/02 , G09B3/00
CPC分类号： G09B7/02
摘要： The present invention relates to a learning system that makes it possible to obtain an answer quickly with simple operation and thus proceed with learning smoothly. When special explanation is required in learning using a personal computer and a projector in a school, the personal computer is connected to a personal computer or a portable terminal of an expert. The projector on the school side displays a picture of the expert. The personal computer or the portable terminal on the expert side displays a picture of the inside of a classroom. The school side transmits a question item from the personal computer to the expert. The expert transmits an answer to the question item from the personal computer or the portable terminal to the school side. The projector on the school side displays the answer from the expert.
摘要翻译：本发明涉及一种能够以简单的操作快速获得答案，从而顺利进行学习的学习系统。当在学校中使用个人计算机和投影仪学习时需要特别说明时，个人计算机连接到专家的个人计算机或便携式终端。学校一侧的投影机显示专家的图片。专家侧的个人计算机或便携式终端显示教室内部的图片。学校方面将问题项目从个人电脑传送给专家。专家将问题项目的答案从个人计算机或便携终端发送到学校一侧。学校方面的投影机显示专家的答案。

4. 发明授权

US5283331A 2-halogeno-oxetanocin A and phosphoric ester thereof 失效
标题翻译： 2-卤代 - 氧杂环鸟素A及其磷酸酯
公开(公告)号：US5283331A
公开(公告)日：1994-02-01
申请号：US804773
申请日：1991-12-09
申请人： Seiichi Saito , Akira Masuda , Masayuki Kitagawa , Nobuyoshi Shimada , Jun-ichi Seki , Hiroo Hoshino , Yukihiro Nishiyama
发明人： Seiichi Saito , Akira Masuda , Masayuki Kitagawa , Nobuyoshi Shimada , Jun-ichi Seki , Hiroo Hoshino , Yukihiro Nishiyama
IPC分类号： A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7076 , A61P31/12 , C07H19/02 , C07H19/16 , C07D473/40 , A61K31/52 , C07F7/18 , C07F9/09
CPC分类号： C07H19/02
摘要： It was found that 2-halogeno-oxetanocin A and 4'-phosphate thereof represented by the following general formula (1): ##STR1## wherein X represents a halogen atom and R represents a hydrogen atom or a phosphoric acid residue ##STR2## or salts thereof exhibit a strong antiviral activity and are useful as an active ingredient of therapeutic drug for viral diseases. Further, it was also found that the compounds of this invention are characterized in that they are not inactivated by adenosine deaminase widely present in living bodies and exhibit a high residual activity.
摘要翻译：发现由以下通式（1）表示的2-卤代 - 氧杂环鸟菌素A和4'-磷酸酯：（*化学结构*）（1）其中X表示卤素原子，R表示氢原子或磷酸酸性残基（*化学结构*）或其盐表现出强的抗病毒活性，可用作病毒性疾病的治疗药物的活性成分。此外，还发现本发明的化合物的特征在于它们不被广泛存在于活体中的腺苷脱氨酶灭活，并且表现出高的残留活性。

5. 发明授权

US5120296A Method and apparatus for forming filter element 失效
标题翻译：用于形成过滤元件的方法和装置
公开(公告)号：US5120296A
公开(公告)日：1992-06-09
申请号：US598775
申请日：1990-10-18
申请人： Yoshimitsu Yamaguchi , Masanori Suzuki , Kanekiyo Narita , Akira Masuda , Yasuo Hibi , Takayuki Suzuki
发明人： Yoshimitsu Yamaguchi , Masanori Suzuki , Kanekiyo Narita , Akira Masuda , Yasuo Hibi , Takayuki Suzuki
IPC分类号： B31B49/00 , B01D29/11 , B01D46/00 , B01D46/24 , B01D46/52 , B26D1/62 , B26D3/14 , B31D5/00 , B31F1/10
CPC分类号： B01D46/521 , B01D29/111 , B01D46/0001 , B01D46/2411 , B26D1/626 , B26D3/14 , B31D5/0082 , B31F1/10 , B01D2201/12 , B01D2201/122 , B01D2279/60 , Y10S493/941
摘要： A tape like material including synthetic resin for a filter element is bent into a corrugated pattern while the material is passed between pairs of forming and cutting rollers. Since pairs of cutters are provided within the rollers and since guide plates are provided around the rollers, the material is held abutting the rollers even when the material is cut by the cutters. The material is then conveyed within a reducing drum. The pitch of the corrugated portions formed on the material is reduced and the material is formed into a semicircular shape within the reducing drum. After passed the reducing drum, the material is transferred to a forming path. Since the forming path has an introducing portion having a semicircular sectional shape similar to that of the material leaving the reducing drum, an outlet portion having a circular sectional shape similar to that of the finished filter element and an intermediate portion having a sectional shape gradually varied from the shape of the introducing portion to the shape of the outlet portion, the material is shaped to a complete circle while the material travels along the forming path. A crystal type filter element is thus formed from a tape like material automatically.
摘要翻译：包括用于过滤器元件的合成树脂的带状材料在材料在成形辊和切割辊之间通过时被弯曲成波纹状图案。由于成对的切割器设置在辊内，并且由于在辊周围设置导向板，所以即使当切割器材料被切割时，材料也保持抵靠辊。然后将材料在还原鼓内输送。形成在材料上的波纹部分的间距减小，并且材料在还原滚筒内形成半圆形。在通过还原鼓之后，将材料转移到成形路径上。由于形成路径具有与离开还原鼓的材料类似的半圆形截面形状的引入部分，具有与完成的过滤元件类似的圆形截面形状的出口部分和具有逐渐变化的截面形状的中间部分从引入部分的形状到出口部分的形状，材料成形为完整的圆形，同时材料沿着成形路径行进。因此，由带状材料自动形成晶体型滤光元件。

6. 发明授权

US4862280A Dual film and video tape camera 失效
标题翻译：双胶片和录像带相机
公开(公告)号：US4862280A
公开(公告)日：1989-08-29
申请号：US178451
申请日：1988-04-01
申请人： Toshiharu Iida , Koji Shimanuki , Kimiaki Nakada , Akira Masuda
发明人： Toshiharu Iida , Koji Shimanuki , Kimiaki Nakada , Akira Masuda
IPC分类号： G03B17/48 , H04N5/225
CPC分类号： G03B17/48 , H04N5/225 , Y10S358/906
摘要： A camera for shooting a movie picture and a still picture has a casing in which a pair of imaging optical systems for shooting a still picture and a movie picture, respectively are opened in a front surface of the casing. A functional section for shooting a still picture is disposed in the proximity of the imaging optical system for shooting a still picture, circuits and mechanisms necessary to shoot a movie picture are located in the rear side of the imaging optical system for shooting a movie picture, and a video tape recording mechanism and circuits related thereto are arranged at the back of the functional section for shooting a still picture. Consequently, a movie picture and a still picture can be shot at the same time. Since a film can be loaded in and removed from the camera through the upper surface of the casing, a statisfactory operability is attained. Furthermore, the casing is provided with a cap covering the upper surface of the casing and hence the casing has an improved strength and effectively prevents water and dust.
摘要翻译：用于拍摄电影图像和静止图像的相机具有壳体，其中用于拍摄静止图像和电影图像的一对成像光学系统分别在壳体的前表面中打开。用于拍摄静止图像的功能部分设置在用于拍摄静止图像的成像光学系统附近，拍摄电影图像所需的电路和机构位于用于拍摄电影图像的成像光学系统的后侧，并且一个录像带记录机构和与之相关的电路布置在用于拍摄静止图像的功能部分的后面。因此，可以同时拍摄电影图像和静止图像。由于可以通过壳体的上表面将胶片装入照相机并从照相机中取出，所以可获得令人满意的可操作性。此外，壳体设置有覆盖壳体的上表面的盖，因此壳体具有改善的强度并且有效地防止水和灰尘。

7. 发明授权

US4788565A Composite camera apparatus composed of video camera and still camera with strobe device 失效
标题翻译：复合摄像机由视频摄像机和静像摄像机组成，具有频闪设备
公开(公告)号：US4788565A
公开(公告)日：1988-11-29
申请号：US133278
申请日：1987-12-15
申请人： Akira Masuda , Yoshiaki Nakayama
发明人： Akira Masuda , Yoshiaki Nakayama
IPC分类号： H04N5/235 , H04N5/238 , H04N5/335 , H04N5/359 , H04N5/372 , H04N5/378 , H04N5/765 , H04N5/91 , G03B17/48
CPC分类号： H04N5/91 , H04N5/2354 , H04N5/765 , Y10S358/906
摘要： A composite camera apparatus employing a video camera device, a still camera device and a strobe device. The video camera device includes an electric circuit for picking up video data and processing the video data to record a video signal on a recording medium, such as a video tape. The electric circuit of the video camera apparatus includes means, associated with a strobe device and responsive to initiation of stroboscopic flashing, for controlling the electric circuit for recording the video signal so that a predetermined number of the video data picked-up at the occurrence of stroboscopic flashing, may not be reproduced when the video signal is reproduced by means of a VTR on a video monitor.

8. 发明授权

US4566417A Fuel injection control apparatus for diesel engines 失效
标题翻译：柴油机燃油喷射控制装置
公开(公告)号：US4566417A
公开(公告)日：1986-01-28
申请号：US598593
申请日：1984-04-10
申请人： Yutaka Suzuki , Nobuhito Hobo , Yoshihiko Tsuzuki , Takashi Naito , Mikio Kumano , Tetsuya Nakamura , Satoshi Haseda , Akira Masuda
发明人： Yutaka Suzuki , Nobuhito Hobo , Yoshihiko Tsuzuki , Takashi Naito , Mikio Kumano , Tetsuya Nakamura , Satoshi Haseda , Akira Masuda
IPC分类号： F02B3/06 , F02D41/40 , F02M51/06 , F02D5/02
CPC分类号： F02D41/408 , F02B3/06 , F02D2200/0406 , Y02T10/44
摘要： A fuel injection arrangement for a diesel engine. An overflow passage for high pressure fuel is provided in the engine's fuel injection pump. A solenoid valve is disposed in the overflow passage for controlling the fuel injection amount through its on-off operation. The time when the fuel injection pump starts injecting fuel is detected by an injection start detector. To this injection starting time point is added a target injection period to determine an injection end time. At this injection end time the solenoid valve is opened to discontinue the fuel injection. The target injection period is determined according to operating conditions of the engine. Since this apparatus detects the actual injection start point and controls the injection period on the basis of the result of the detection, the fuel injection amount can be controlled extremely accurately.
摘要翻译：一种用于柴油发动机的燃料喷射装置。在发动机的燃料喷射泵中设置有用于高压燃料的溢流通道。电磁阀设置在溢流通道中，用于通过其开 - 关操作来控制燃料喷射量。燃料喷射泵开始喷射燃料的时间由喷射启动检测器检测。在该喷射开始时间点中添加目标喷射周期以确定喷射结束时间。在此注射结束时，电磁阀打开以中断燃油喷射。目标喷射周期根据发动机的运行条件来确定。由于该装置基于检测结果来检测实际的喷射开始点并控制喷射期间，所以可以极其精确地控制燃料喷射量。

9. 发明授权

US4499883A Distributor type fuel-injection pump for distributing fuel to cylinders of an internal combustion engine 失效
标题翻译：用于将燃料分配到内燃机的气缸的分配器型燃料喷射泵
公开(公告)号：US4499883A
公开(公告)日：1985-02-19
申请号：US564408
申请日：1983-12-22
申请人： Masahiko Miyaki , Akira Masuda , Toshimi Matsumura
发明人： Masahiko Miyaki , Akira Masuda , Toshimi Matsumura
IPC分类号： F02M41/14 , F04B19/00
CPC分类号： F02M41/1411
摘要： A distributor type fuel-injection pump according to the present invention is provided with a rotor which is rotated by an engine. The rotor has a pair of plungers slidable in the radial direction of the rotor, and a fuel pumping chamber is defined between the plungers. The rotor is surrounded by a cam ring which reciprocates the plungers as the rotor rotates, thereby sucking fuel into the fuel pumping chamber and pressurizing the fuel therein. The fuel pressurized in the fuel pumping chamber is distributed to individual cylinders of the engine. A plurality of spill holes are formed in the rotor, communicating with the fuel pumping chamber and opening to the outer peripheral surface of the rotor. A control sleeve to open and close the spill holes is axially slidably fitted on the rotor. First and second spill grooves capable of communicating with the spill holes are formed on the inner peripheral surface of the control sleeve. The first and second spill grooves open or close the spill holes to define the timing for the start of fuel delivery in the fuel pumping chamber and the timing for the end of fuel delivery, thereby determining the amount of fuel delivery.
摘要翻译：根据本发明的分配器式燃料喷射泵设置有由发动机旋转的转子。转子具有可沿转子的径向滑动的一对柱塞，并且在柱塞之间限定燃料泵送室。转子由转子围绕，当转子旋转时往复运动的凸轮环，从而将燃料吸入燃料泵送室并对其中的燃料加压。在燃料泵送室中加压的燃料被分配到发动机的各个气缸。在转子中形成有多个泄漏孔，与燃料泵送室连通并且向转子的外周面开口。用于打开和关闭泄漏孔的控制套筒可轴向滑动地安装在转子上。能够与溢出孔连通的第一和第二溢出槽形成在控制套筒的内周面上。第一和第二泄漏槽打开或关闭泄漏孔，以限定燃料泵送室中的燃料开始开始的时间和燃料输送结束的时间，从而确定燃料输送量。

10. 发明授权

US4479464A Air-to-fuel ratio correcting arrangement in a fuel supply control system having a feedback loop 失效
标题翻译：具有反馈回路的燃料供给控制系统中的空燃比校正装置
公开(公告)号：US4479464A
公开(公告)日：1984-10-30
申请号：US940388
申请日：1978-09-07
申请人： Toshio Kondo , Hideaki Norimatsu , Mitsuo Nakamura , Akira Masuda , Sigenori Kitazima
发明人： Toshio Kondo , Hideaki Norimatsu , Mitsuo Nakamura , Akira Masuda , Sigenori Kitazima
IPC分类号： F02D41/14 , F02B33/00
CPC分类号： F02D41/1488
摘要： The air-to-fuel ratio of a combustible mixture supplied to an engine is controlled by a feedback loop which includes an integration circuit for integrating the output signal of an oxygen sensor which detects the oxygen concentration in the exhaust gases of the engine, to produce an output voltage. The output of the sensor is applied to the integration circuit through a switch which opens in response to predetermined conditions of the engine whereby the output voltage of the integration circuit is held at a value occurring just before the switch opens.
摘要翻译：提供给发动机的可燃混合物的空燃比通过反馈回路控制，反馈回路包括用于积分检测发动机排气中的氧气浓度的氧传感器的输出信号的积分电路，以产生输出电压。传感器的输出通过响应于发动机的预定条件打开的开关施加到积分电路，由此积分电路的输出电压保持在开关打开之前的值。

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