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1. 发明申请

US20130084629A1 Nucleic Acid Analysis Reaction Cell and Nucleic Acid Analyzer 有权
标题翻译：核酸分析反应池和核酸分析仪
公开(公告)号：US20130084629A1
公开(公告)日：2013-04-04
申请号：US13696962
申请日：2011-04-20
申请人： Taro Nakazawa , Masatoshi Narahara , Ryoji Inaba , Yoshihiro Nagaoka , Shigenori Togashi
发明人： Taro Nakazawa , Masatoshi Narahara , Ryoji Inaba , Yoshihiro Nagaoka , Shigenori Togashi
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6844 , B01L3/502746 , B01L2300/0816 , B01L2300/0861 , B01L2300/0864 , B01L2300/0877 , B01L2300/0887 , B01L2400/086 , G01N27/447 , G01N35/1095
摘要： A nucleic acid analysis reaction cell and a nucleic acid analyzer are provided, in which a uniform flow rate is realised, so that a portion where a flow rate is low is removed and washing time for reagent removal is shortened.A flow path (103) is provided which includes a detection area (108) for detecting sequence information of a nucleic acid fragment and detection outer areas (107) disposed at both ends of the detection area (108). An inflow port (105) is provided in one of the detection outer areas (107) and a discharge port (106) is provided in the other of the detection outer areas (107). The detection outer areas (107) disposed at both the ends of the detection area (108) are areas whose widths become narrow toward ends, and guides (104) for branching a liquid are provided in at least the detection outer area (107) in which the inflow port (105) is provided.
摘要翻译：提供了一种核酸分析反应池和核酸分析仪，其中实现了均匀的流速，从而消除了流速低的部分，缩短了除去试剂的洗涤时间。提供了一种流路（103），其包括用于检测核酸片段的序列信息的检测区域（108）和设置在检测区域（108）两端的检测外部区域（107）。在一个检测外部区域（107）中设置有流入口（105），并且在另一个检测外部区域（107）中设置有排出口（106）。设置在检测区域（108）的两端的检测外部区域（107）是宽度朝向端部变窄的区域，并且至少在检测外部区域（107）中设置用于分支液体的引导件（104）其中设置有流入口（105）。

2. 发明授权

US09150911B2 Nucleic acid analysis reaction cell and nucleic acid analyzer 有权
标题翻译：核酸分析反应池和核酸分析仪
公开(公告)号：US09150911B2
公开(公告)日：2015-10-06
申请号：US13696962
申请日：2011-04-20
申请人： Taro Nakazawa , Masatoshi Narahara , Ryoji Inaba , Yoshihiro Nagaoka , Shigenori Togashi
发明人： Taro Nakazawa , Masatoshi Narahara , Ryoji Inaba , Yoshihiro Nagaoka , Shigenori Togashi
IPC分类号： C12Q1/68 , B01L3/00 , G01N27/447 , G01N35/10
CPC分类号： C12Q1/6844 , B01L3/502746 , B01L2300/0816 , B01L2300/0861 , B01L2300/0864 , B01L2300/0877 , B01L2300/0887 , B01L2400/086 , G01N27/447 , G01N35/1095
摘要： A nucleic acid analysis reaction cell and a nucleic acid analyzer are provided, in which a uniform flow rate is realized, so that a portion where a flow rate is low is removed and washing time for reagent removal is shortened.A flow path (103) is provided which includes a detection area (108) for detecting sequence information of a nucleic acid fragment and detection outer areas (107) disposed at both ends of the detection area (108). An inflow port (105) is provided in one of the detection outer areas (107) and a discharge port (106) is provided in the other of the detection outer areas (107). The detection outer areas (107) disposed at both the ends of the detection area (108) are areas whose widths become narrow toward ends, and guides (104) for branching a liquid are provided in at least the detection outer area (107) in which the inflow port (105) is provided.
摘要翻译：提供了一种核酸分析反应池和核酸分析仪，其中实现了均匀的流速，从而消除了流速低的部分，缩短了除去试剂的洗涤时间。提供了一种流路（103），其包括用于检测核酸片段的序列信息的检测区域（108）和设置在检测区域（108）两端的检测外部区域（107）。在一个检测外部区域（107）中设置有流入口（105），并且在另一个检测外部区域（107）中设置有排出口（106）。设置在检测区域（108）的两端的检测外部区域（107）是宽度朝向端部变窄的区域，并且至少在检测外部区域（107）中设置用于分支液体的引导件（104）其中设置有流入口（105）。

3. 发明申请

US20120127469A1 FLOW CELL, DETECTOR, AND LIQUID CHROMATOGRAPH 审中-公开
标题翻译：流动池，检测器和液相色谱
公开(公告)号：US20120127469A1
公开(公告)日：2012-05-24
申请号：US13388765
申请日：2010-06-18
申请人： Nobuhiro Tsukada , Shigenori Togashi , Yoshihiro Nagaoka , Tomohiro Shoji
发明人： Nobuhiro Tsukada , Shigenori Togashi , Yoshihiro Nagaoka , Tomohiro Shoji
IPC分类号： G01N21/59
CPC分类号： G01N30/74 , G01N2030/746
摘要： In a liquid chromatograph, a flow cell, in which a direction of detecting light and a flow direction of a sample fluid are parallel to each other, and in which the flow direction of the sample fluid changes at the moment of the sample fluid flowing out of a detecting portion into an outflow channel and at the moment of the sample fluid flowing into the detecting portion from an inflow channel, is capable of suppressing a peak broadening of a chromatogram. A plurality of outflow channels are provided, which shorten a distance between a flow outlet and a flow bend in the sample flow. A plurality of inflow channels are also provided, some of which collide jets flowing into the detecting portion from the inflow channels and others of which produce a swirl of jets flowing into the detecting portion from the inflow channels.
摘要翻译：在液相色谱仪中，流动池中检测光的方向和样品流体的流动方向彼此平行，并且样品流体流动方向在样品流体流出时变化的流动池的检测部分流入流出通道，并且在样品流体从流入通道流入检测部分的时刻能够抑制色谱图的峰值变宽。提供了多个流出通道，其缩短了流出口和样品流中的流动弯曲之间的距离。还设置有多个流入通道，其中一些流入通道从流入通道碰撞流入检测部分的射流，其中一些从流入通道产生流入检测部分的喷流漩涡。

4. 发明授权

US08287179B2 Fluid mixer 失效
标题翻译：流体搅拌机
公开(公告)号：US08287179B2
公开(公告)日：2012-10-16
申请号：US12708070
申请日：2010-02-18
申请人： Tetsuro Miyamoto , Yoshishige Endo , Shigenori Togashi , Erika Katayama
发明人： Tetsuro Miyamoto , Yoshishige Endo , Shigenori Togashi , Erika Katayama
IPC分类号： B01F5/04
CPC分类号： B01F5/0665 , B01F5/0679 , B01F13/0062 , B01F13/0066
摘要： A fluid mixer for mixing a first fluid and a second fluid includes an introducing component having a bore, a cylindrical component fitted into the bore of the introducing component and a mixing component having a conical recess and on which the introducing component and the cylindrical component are held. A first introducing flow path receives the first fluid and a first distributing flow path distributes the first fluid over the whole circumference of the cylindrical component. A second introducing flow path receives the second fluid. A second distributing flow path distributes the second fluid so that the first fluid and the second fluid are alternately arranged in an circumferential direction. A joining part joins together the first fluid and the second fluid fed with the fluids alternately arranged circumferentially.
摘要翻译：用于混合第一流体和第二流体的流体混合器包括具有孔的引入部件，装配在引入部件的孔中的圆柱形部件和具有锥形凹部的混合部件，引导部件和圆柱形部件保持。第一引入流动路径接收第一流体，并且第一分配流动路径将第一流体分布在圆柱形部件的整个圆周上。第二引入流路接收第二流体。第二分配流路分配第二流体，使得第一流体和第二流体沿圆周方向交替布置。接合部将第一流体和供给有周向交替布置的流体的第二流体连接在一起。

5. 发明授权

US08252239B2 Liquid-liquid extraction system 失效
标题翻译：液 - 液萃取系统
公开(公告)号：US08252239B2
公开(公告)日：2012-08-28
申请号：US12783924
申请日：2010-05-20
申请人： Mami Hakari , Shigenori Togashi , Yasuhiko Sasaki
发明人： Mami Hakari , Shigenori Togashi , Yasuhiko Sasaki
IPC分类号： B06B1/20 , B01D11/00 , B01D17/02
CPC分类号： B01D11/04 , B01D11/0265 , B01D11/0496 , B01F3/0819 , B01F11/0283
摘要： The invention aims to reduce the processing time of liquid-liquid extraction, reduce variations in the amount of extraction of a solute, and improve the extraction efficiency. Provided are a container adapted to contain a continuous phase and a dispersion phase that are mutually immiscible liquids, and a solute dissolved in at least one of the continuous and dispersion phases, a water tank accommodating therein the container and containing water around the container, an emulsification ultrasonic oscillation source disposed outside the water tank, on a plane substantially parallel with the interface between the continuous and dispersion phases, a separation ultrasonic oscillation source disposed outside the water tank, an ultrasonic-oscillation-source driving circuit configured to drive the emulsification ultrasonic oscillation source and the separation ultrasonic oscillation source, and a control unit configured to control the ultrasonic-oscillation-source driving circuit such that it sequentially drives the emulsification ultrasonic oscillation source and the separation ultrasonic oscillation source.
摘要翻译：本发明旨在减少液 - 液萃取的处理时间，减少溶质萃取量的变化，提高萃取效率。提供一种容器，其适于容纳相互不混溶的液体的连续相和分散相，以及溶解在至少一个连续分散相中的溶质，在其中容纳容器并在容器周围容纳水的水箱，乳化超声波振荡源设置在水箱外部，与基本上平行于连续分散相之间的界面的平面上，设置在水箱外部的分离超声波振荡源，构造成驱动乳化超声波的超声波振荡源驱动电路振荡源和分离超声波振荡源，以及控制单元，被配置为控制超声波振荡源驱动电路，使得其依次驱动乳化超声波振荡源和分离超声波振荡源。

6. 发明申请

US20100296976A1 LIQUID-LIQUID EXTRACTION SYSTEM 失效
标题翻译：液体萃取系统
公开(公告)号：US20100296976A1
公开(公告)日：2010-11-25
申请号：US12783924
申请日：2010-05-20
申请人： Mami HAKARI , Shigenori Togashi , Yasuhiko Sasaki
发明人： Mami HAKARI , Shigenori Togashi , Yasuhiko Sasaki
IPC分类号： B06B1/20 , B01D11/00 , B01D17/02
CPC分类号： B01D11/04 , B01D11/0265 , B01D11/0496 , B01F3/0819 , B01F11/0283
摘要： The invention aims to reduce the processing time of liquid-liquid extraction, reduce variations in the amount of extraction of a solute, and improve the extraction efficiency. Provided are a container adapted to contain a continuous phase and a dispersion phase that are mutually immiscible liquids, and a solute dissolved in at least one of the continuous and dispersion phases, a water tank accommodating therein the container and containing water around the container, an emulsification ultrasonic oscillation source disposed outside the water tank, on a plane substantially parallel with the interface between the continuous and dispersion phases, a separation ultrasonic oscillation source disposed outside the water tank, an ultrasonic-oscillation-source driving circuit configured to drive the emulsification ultrasonic oscillation source and the separation ultrasonic oscillation source, and a control unit configured to control the ultrasonic-oscillation-source driving circuit such that it sequentially drives the emulsification ultrasonic oscillation source and the separation ultrasonic oscillation source.
摘要翻译：本发明旨在减少液 - 液萃取的处理时间，减少溶质萃取量的变化，提高萃取效率。提供一种容器，其适于容纳相互不混溶的液体的连续相和分散相，以及溶解在至少一个连续分散相中的溶质，在其中容纳容器并在容器周围容纳水的水箱，乳化超声波振荡源设置在水箱外部，与基本上平行于连续分散相之间的界面的平面上，设置在水箱外部的分离超声波振荡源，构造成驱动乳化超声波的超声波振荡源驱动电路振荡源和分离超声波振荡源，以及控制单元，被配置为控制超声波振荡源驱动电路，使得其依次驱动乳化超声波振荡源和分离超声波振荡源。

7. 发明授权

US07561389B2 Alternating-current voltage output apparatus 有权
标题翻译：交流电压输出装置
公开(公告)号：US07561389B2
公开(公告)日：2009-07-14
申请号：US11660084
申请日：2006-05-02
申请人： Tetsuhiro Ishikawa , Hichirosai Oyobe , Yukihiro Minezawa , Shigenori Togashi
发明人： Tetsuhiro Ishikawa , Hichirosai Oyobe , Yukihiro Minezawa , Shigenori Togashi
IPC分类号： H02H3/00 , H02H9/08 , F21V7/04 , H02M7/48
CPC分类号： H02H3/00 , B60L3/0069 , B60L3/0092 , B60L3/04 , B60L11/123 , B60L11/14 , B60L11/1814 , B60L11/1842 , B60L2210/20 , B60L2220/14 , B60L2220/54 , B60L2240/423 , B60W10/08 , B60W20/00 , B60W2710/083 , H02H9/08 , Y02E60/721 , Y02T10/6217 , Y02T10/641 , Y02T10/642 , Y02T10/7005 , Y02T10/7022 , Y02T10/7072 , Y02T10/7077 , Y02T10/725 , Y02T90/121 , Y02T90/127 , Y02T90/128 , Y02T90/14 , Y02T90/163 , Y04S10/126
摘要： Inverters, based on signals from a control device, generate a commercial AC voltage across neutral points of 3-phase coils. A Y-capacitor for removing noise is connected to a load outside the vehicle receiving the supply of the commercial AC voltage. A relay connected in series with a leakage detecting device is provided inside the vehicle. The relay is turned off when a plug of the load outside the vehicle is connected to a connector, and prevents a leakage current from flowing via a ground.
摘要翻译：逆变器基于来自控制装置的信号，在三相线圈的中性点上产生商业交流电压。用于消除噪声的Y电容器连接到接收商用AC电压供应的车辆外的负载。在车辆内部设置有与泄漏检测装置串联连接的继电器。当车辆外部的负载插头连接到连接器时，继电器关闭，并防止漏电流通过地面流动。

8. 发明授权

US07330334B2 Magnetic disk apparatus with shroud and having open space downstream of moveable arms in communication with bypass channel 失效
标题翻译：具有护罩的磁盘装置，并且具有与旁路通道连通的可动臂下游的开放空间
公开(公告)号：US07330334B2
公开(公告)日：2008-02-12
申请号：US11129335
申请日：2005-05-16
申请人： Hayato Shimizu , Masao Iwakura , Shigeo Nakamura , Kazuo Sakai , Shigenori Togashi , Masayuki Kaiho , Toshiaki Kobari , Mikio Tokuyama , Satomitsu Imai , Shozo Saegusa , Masahiko Sega , Toshihisa Okazaki , Yuzo Yamaguchi
发明人： Hayato Shimizu , Masao Iwakura , Shigeo Nakamura , Kazuo Sakai , Shigenori Togashi , Masayuki Kaiho , Toshiaki Kobari , Mikio Tokuyama , Satomitsu Imai , Shozo Saegusa , Masahiko Sega , Toshihisa Okazaki , Yuzo Yamaguchi
IPC分类号： G11B33/14
CPC分类号： G11B25/043 , G11B5/6005 , G11B33/142 , G11B33/1446 , G11B33/148
摘要： A magnetic disk apparatus includes a plurality of magnetic disks driven to rotate by a spindle motor, arms supporting magnetic heads on the magnetic disks, an actuator for moving the arms on the magnetic disks by a voice coil motor, and a housing which surrounds the magnetic disks, the arms and the actuator. A shroud which arcuately surrounds the magnetic disks along the outer periphery thereof has an opened portion for inserting the arms is formed in a part of the housing. The shroud on an upstream side of the arms relative to airflow generated by the magnetic disks when rotating is provided with an opening having a greater width than that of a gap defined between the shroud and the outer periphery of the magnetic disks. An empty bypass channel is provided which communicates from the opening through a rear side of the voice coil motor to the downstream side of the arms.
摘要翻译：一种磁盘装置，包括由主轴电动机驱动旋转的多个磁盘，支撑在磁盘上的磁头的臂，用于通过音圈电机将臂支撑在磁盘上的致动器，以及围绕磁性的壳体磁盘，臂和致动器。沿其外周弧形围绕磁盘的护罩具有用于插入臂的开口部分形成在壳体的一部分中。臂相对于旋转时由磁盘产生的气流在臂的上游侧的护罩设置有具有比限定在护罩与磁盘外周之间的间隙大的宽度的开口。提供了一个空的旁路通道，其从开口通过音圈马达的后侧连通到臂的下游侧。

9. 发明申请

US20070247770A1 Alternating-Current Voltage Output Appartus 有权
标题翻译：交流电压输出
公开(公告)号：US20070247770A1
公开(公告)日：2007-10-25
申请号：US11660084
申请日：2006-05-02
申请人： Tetsuhiro Ishikawa , Hichirosai Oyobe , Yukihiro Minezawa , Shigenori Togashi
发明人： Tetsuhiro Ishikawa , Hichirosai Oyobe , Yukihiro Minezawa , Shigenori Togashi
IPC分类号： H02H9/08
CPC分类号： H02H3/00 , B60L3/0069 , B60L3/0092 , B60L3/04 , B60L11/123 , B60L11/14 , B60L11/1814 , B60L11/1842 , B60L2210/20 , B60L2220/14 , B60L2220/54 , B60L2240/423 , B60W10/08 , B60W20/00 , B60W2710/083 , H02H9/08 , Y02E60/721 , Y02T10/6217 , Y02T10/641 , Y02T10/642 , Y02T10/7005 , Y02T10/7022 , Y02T10/7072 , Y02T10/7077 , Y02T10/725 , Y02T90/121 , Y02T90/127 , Y02T90/128 , Y02T90/14 , Y02T90/163 , Y04S10/126
摘要： Inverters (20, 30), based on signals PWM1, PWM2 from a control device (70), generate a commercial AC voltage Vac across neutral points (N1, N2) of 3-phase coils (12, 14). A Y-capacitor (84) for removing noise is connected to a load (80) outside the vehicle receiving the supply of the commercial AC voltage Vac. A relay (RY3) connected in series with a leakage detecting device (60) is provided inside the vehicle. The relay (RY3) is turned off when a plug (82) of the load (80) outside the vehicle is connected to a connector (50), and prevents a leakage current from flowing via a ground.
摘要翻译：基于来自控制装置（70）的信号PWM 1，PWM 2的逆变器（20,30）在三相线圈（12,14）的中性点（N 1，N 2）上产生商用AC电压Vac。用于消除噪声的Y电容器（84）连接到接收商用AC电压Vac的电源的车辆外的负载（80）。在车辆内部设置与漏电检测装置（60）串联连接的继电器（RY3）。当车辆外部的负载（80）的插头（82）连接到连接器（50）时，继电器（RY 3）被断开，并且防止漏电流经由地面流动。

10. 发明申请

US20060210444A1 Equipment and method for manufacturing substances 审中-公开
标题翻译：制造物质的设备和方法
公开(公告)号：US20060210444A1
公开(公告)日：2006-09-21
申请号：US11375114
申请日：2006-03-15
申请人： Yukako Asano , Shigenori Togashi , Masashi Oda , Tomofumi Shiraishi , Tsutomu Kawamura
发明人： Yukako Asano , Shigenori Togashi , Masashi Oda , Tomofumi Shiraishi , Tsutomu Kawamura
IPC分类号： B01L3/00
CPC分类号： B01J19/0093 , B01F13/0059 , B01F13/0093 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00961 , B01J2219/00984 , B01J2219/00986 , B01J2219/00995 , F28D2021/0077
摘要： There is provided means for increasing a yield and a selectivity of objective substancean objective substance in a consecutive reaction. A substance manufacturing equipment for reacting a substance A and a substance B that can perform a consecutive reaction to produce a product of a first stage reaction as an objective substance, including: a microchannel; a mixing portion including a channel for introducing a solution containing the substance A into the microchannel and a channel for introducing a solution containing the substance B into the microchannel; and a temperature control equipment for controlling a temperature of a reaction system in the microchannel, wherein the temperature control equipment controls the temperature of the reaction system in the microchannel within a temperature range higher than a reaction temperature by a batch method and lower than a boiling point of the reaction system.
摘要翻译：提供了在连续反应中提高目标物质的产率和选择性的方法。一种使物质A和物质B反应的物质制造设备，其可以进行连续反应以产生作为目标物质的第一级反应的产物，包括：微通道; 混合部分，其包括用于将含有物质A的溶液引入微通道的通道和用于将含有物质B的溶液引入微通道的通道; 以及用于控制微通道中的反应系统的温度的温度控制设备，其中温度控制设备通过间歇法控制微通道内的反应体系在比反应温度高的温度范围内的温度，并且低于沸点点反应体系。

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