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    • 3. 发明授权
    • Method for producing bioactive composites
    • 生物活性复合材料的生产方法
    • US08512732B2
    • 2013-08-20
    • US12305270
    • 2007-06-19
    • Takeshi YaoMitsuhiro HibinoTakeshi Yabutsuka
    • Takeshi YaoMitsuhiro HibinoTakeshi Yabutsuka
    • A61F2/00A01N59/26A61K33/42A61L27/32B05D3/00
    • A61L27/56A61L27/32C08J9/40C08J2201/038
    • An object of the present invention is to provide a method for producing bioactive composites having imparted thereto bioactivity, to thereby form and grow in vivo or in vitro a coating layer containing a calcium phosphate compound as the major component with a high adhesion strength on the surface of various types of porous substrates such as a porous shaped body comprising an organic polymer. The means for solving the problem is characterized by comprising at least (1) a step of immersing a porous substrate in a solution containing at least calcium ions and hydrogenphosphate ions, thereby distributing the solution to the inside of at least a part of the pores of the substrate, and (2) a step of depositing fine particles containing a calcium phosphate compound as the major component inside the pores into which the solution is introduced.
    • 本发明的目的是提供一种赋予生物活性的生物活性复合材料的方法,从而在体内或体外形成和生长含有磷酸钙化合物作为主要成分的涂层,在表面上具有高粘合强度 的各种类型的多孔基材,例如包含有机聚合物的多孔成形体。 解决问题的手段的特征在于至少包括(1)将多孔基材浸渍在至少含有钙离子和磷酸氢根离子的溶液中的步骤,从而将溶液分配到至少一部分孔的内部 所述基板,以及(2)将含有磷酸钙化合物的微粒子作为主要成分的细粒沉积在所述溶液引入的孔内的工序。
    • 4. 发明申请
    • METHOD FOR PRODUCING BIOACTIVE COMPOSITES
    • 生产生物复合材料的方法
    • US20090324673A1
    • 2009-12-31
    • US12305270
    • 2007-06-19
    • Takeshi YaoMitsuhiro HibinoTakeshi Yabutsuka
    • Takeshi YaoMitsuhiro HibinoTakeshi Yabutsuka
    • A61K33/42B05D3/00B05D3/06A61F2/28A61P19/00
    • A61L27/56A61L27/32C08J9/40C08J2201/038
    • An object of the present invention is to provide a method for producing bioactive composites having imparted thereto bioactivity, to thereby form and grow in vivo or in vitro a coating layer containing a calcium phosphate compound as the major component with a high adhesion strength on the surface of various types of porous substrates such as a porous shaped body comprising an organic polymer. The means for solving the problem is characterized by comprising at least (1) a step of immersing a porous substrate in a solution containing at least calcium ions and hydrogenphosphate ions, thereby distributing the solution to the inside of at least a part of the pores of the substrate, and (2) a step of depositing fine particles containing a calcium phosphate compound as the major component inside the pores into which the solution is introduced.
    • 本发明的目的是提供一种赋予生物活性的生物活性复合材料的方法,从而在体内或体外形成和生长含有磷酸钙化合物作为主要成分的涂层,在表面上具有高粘合强度 的各种类型的多孔基材,例如包含有机聚合物的多孔成形体。 解决问题的手段的特征在于至少包括(1)将多孔基材浸渍在至少含有钙离子和磷酸氢根离子的溶液中的步骤,从而将溶液分配到至少一部分孔的内部 所述基板,以及(2)将含有磷酸钙化合物的微粒子作为主要成分的细粒沉积在所述溶液引入的孔内的工序。
    • 9. 发明授权
    • Metal oxide pattern forming method
    • 金属氧化物图案形成方法
    • US06679996B1
    • 2004-01-20
    • US09680257
    • 2000-10-05
    • Takeshi Yao
    • Takeshi Yao
    • B44C122
    • H01L21/31604C23C18/06C23C18/1216C23C26/00
    • In a pattern forming method for selectively forming an oxide layer on a substrate surface, the substrate surface is selectively coated with a coating layer. On the coating layer and an exposed part of the substrate surface, an oxide layer is formed by the use of a predetermined solution. Subsequently, the oxide layer on the coating layer is removed together with the coating layer to selectively leave the oxide layer on the substrate surface. Thus, a pattern is formed. The coating layer is removed in a liquid phase or optically together with the oxide layer on the coating layer. The oxide layer is formed by the use of, as the predetermined solution, an aqueous solution or a hydrofluoric acid solution of a fluoro metal complex compound and/or metal fluoride of at least one element selected from the group consisting of alkaline earth metal, transition metal, gallium, indium, silicon, tin, lead, antimony, and bismuth in the presence of an fluoride ion capturing agent.
    • 在用于在衬底表面上选择性地形成氧化物层的图案形成方法中,衬底表面选择性地涂覆有涂层。 在涂层和基板表面的暴露部分上,通过使用预定的溶液形成氧化物层。 随后,涂层上的氧化物层与涂层一起被去除,以选择性地将氧化物层留在衬底表面上。 因此,形成图案。 将涂层以液相或与涂层上的氧化物层一起光学地除去。 通过使用作为预定溶液的氟化金属络合物和/或选自碱土金属,过渡金属的至少一种元素的金属氟化物的水溶液或氢氟酸溶液形成氧化物层 金属,镓,铟,硅,锡,铅,锑和铋在氟离子捕获剂的存在下。