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1. 发明授权

US06327493B1 Light scanning devices of a water-tight structure to be inserted into a body cavity to obtain optical information on inside of a biological tissue 有权
标题翻译：将要插入体腔的水密结构的光扫描装置获得生物组织内部的光学信息
公开(公告)号：US06327493B1
公开(公告)日：2001-12-04
申请号：US09141572
申请日：1998-08-27
申请人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Atsushi Okawa , Hiroki Hibino , Hiroyuki Sangu , Hitoshi Ueno , Hitoshi Mizuno , Jun Hiroya , Katsuichi Imaizumi , Hidemichi Aoki , Masahiro Ohno , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino , Sakae Takehana , Isami Hirao , Takefumi Uesugi , Toshimasa Kawai
发明人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Atsushi Okawa , Hiroki Hibino , Hiroyuki Sangu , Hitoshi Ueno , Hitoshi Mizuno , Jun Hiroya , Katsuichi Imaizumi , Hidemichi Aoki , Masahiro Ohno , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino , Sakae Takehana , Isami Hirao , Takefumi Uesugi , Toshimasa Kawai
IPC分类号： A61B600
CPC分类号： A61B5/0073 , A61B5/0066 , A61B5/0068
摘要： A light scanning device has a tip structure which includes a light scanning part connected to a light source, and which is insertable into a body cavity and is formed so as to be water-tight. A controlling part controls the light scan through the tip structure, and the tip structure and the controlling part are also connected to each other in a water-tight manner by a slender tube through which a plurality of electrical cables pass. An electric connector is fixed with the proximal end portion of the tube in a water-tight manner, and is electrically connectable so as to be water-tight with and removable from this controlling part.
摘要翻译：光扫描装置具有尖端结构，该尖端结构包括连接到光源的光扫描部分，并且其可插入体腔中并且被形成为防水的。控制部分通过尖端结构控制光扫描，并且尖端结构和控制部分也通过多根电缆通过的细长管以水密的方式彼此连接。电连接器以水密方式与管的近端部分固定，并且可电连接以便与该控制部件具有防水性和可拆卸性。

2. 发明授权

US6069698A Optical imaging apparatus which radiates a low coherence light beam onto a test object, receives optical information from light scattered by the object, and constructs therefrom a cross-sectional image of the object 有权
标题翻译：将低相干光束照射到测试对象上的光学成像设备从由物体散射的光接收光学信息，并由其构造物体的横截面图像
公开(公告)号：US6069698A
公开(公告)日：2000-05-30
申请号：US141430
申请日：1998-08-27
申请人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Hitoshi Ueno , Sakae Takehana , Hiroyuki Sangu , Isami Hirao , Hitoshi Mizuno , Toshimasa Kawai , Hiroki Hibino , Hideyuki Adachi , Hironobu Takizawa , Takefumi Uesugi , Masahiro Ohno , Hidemichi Aoki , Jun Hiroya , Katsuichi Imaizumi , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino
发明人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Hitoshi Ueno , Sakae Takehana , Hiroyuki Sangu , Isami Hirao , Hitoshi Mizuno , Toshimasa Kawai , Hiroki Hibino , Hideyuki Adachi , Hironobu Takizawa , Takefumi Uesugi , Masahiro Ohno , Hidemichi Aoki , Jun Hiroya , Katsuichi Imaizumi , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino
IPC分类号： A61B5/00 , G01B9/02
CPC分类号： G01B9/02069 , A61B5/0062 , A61B5/0066 , A61B5/0084 , G01B9/0205 , G01B9/02064 , G01B9/02091 , A61B5/0086 , G01B2290/35 , G01B2290/65
摘要： A low coherence beam emitted by a low coherence light source is split into two portions. One portion is transmitted from the outward end of a first single mode fiber via a detachable connector to a beam scanning probe, and then to a biological tissue; and the other is transmitted from an optical coupler placed midway along the light path via a second single mode fiber to a light path modifier. The light path modifier includes a galvanometer mirror to modify the light path length in accordance with a scan range, and a uniaxial stage to adjust the light path length to absorb the variation in lengths of different beam scanning probes. The light path is adjusted by the uniaxial stage such that the beam interference is detected for the scan range, to ensure stable acquisition of tomographic images.
摘要翻译：由低相干光源发射的低相干光束被分成两部分。一部分从第一单模光纤的外端通过可拆卸连接器传输到光束扫描探针，然后传输到生物组织; 另一个从位于光路的中途的光耦合器经由第二单模光纤传输到光路修正器。光路修正器包括根据扫描范围修改光路长度的电流计镜，以及调整光路长度以吸收不同束扫描探针的长度变化的单轴阶段。通过单轴阶段调整光路，使得在扫描范围内检测光束干涉，以确保断层图像的稳定采集。

3. 发明授权

US5876325A Surgical manipulation system 失效
标题翻译：手术操纵系统
公开(公告)号：US5876325A
公开(公告)日：1999-03-02
申请号：US940613
申请日：1997-09-30
申请人： Hitoshi Mizuno , Yuuichi Ikeda , Akihiro Horii , Shuichi Takayama , Akio Nakada , Naoki Uchiyama , Yasuhiro Ueda , Koichi Umeyama , Sakae Takehana
发明人： Hitoshi Mizuno , Yuuichi Ikeda , Akihiro Horii , Shuichi Takayama , Akio Nakada , Naoki Uchiyama , Yasuhiro Ueda , Koichi Umeyama , Sakae Takehana
IPC分类号： A61B1/00 , A61B1/04 , A61B19/00
CPC分类号： A61B1/00193 , A61B1/00048 , A61B1/00149 , A61B1/00188 , A61B34/30 , A61B34/37 , A61B34/74 , A61B1/042 , A61B2034/301 , A61B2034/742 , A61B2090/502 , A61B2090/506 , G05B2219/39442
摘要： A surgical manipulator system comprising at least one surgical manipulator, at least one guide, a detector, and a drive controller. The surgical manipulator has a surgical device for performing a desired operation. The guide guides the surgical device. The detector detects a position and/or orientation relationship between the surgical device and the guide, and/or a position and/or orientation relationship between the surgical device and another surgical device. The drive controller controls the surgical manipulator such that the surgical device is guided by the guide.
摘要翻译：一种手术操纵器系统，包括至少一个手术操纵器，至少一个引导件，检测器和驱动器控制器。手术操纵器具有用于执行所需操作的手术装置。引导件引导手术装置。检测器检测手术装置和引导件之间的位置和/或取向关系，和/或手术装置与另一手术装置之间的位置和/或取向关系。驱动器控制器控制手术操纵器，使得外科装置由引导件引导。

4. 发明授权

US5836869A Image tracking endoscope system 失效
标题翻译：图像跟踪内窥镜系统
公开(公告)号：US5836869A
公开(公告)日：1998-11-17
申请号：US551713
申请日：1995-11-01
申请人： Masahiro Kudo , Kuniaki Kami , Hiroki Hibino , Hitoshi Mizuno , Akihiro Horii , Susumu Takahashi , Noriyuki Tateyama
发明人： Masahiro Kudo , Kuniaki Kami , Hiroki Hibino , Hitoshi Mizuno , Akihiro Horii , Susumu Takahashi , Noriyuki Tateyama
IPC分类号： A61B1/00 , A61B1/01 , A61B1/04 , A61B1/313 , A61B5/11 , A61B19/00
CPC分类号： A61B1/00149 , A61B1/00006 , A61B1/00009 , A61B1/00039 , A61B1/00188 , A61B1/042 , A61B34/20 , A61B5/064 , A61B90/92 , A61B1/313 , A61B17/3421 , A61B2034/2051 , A61B2034/2055 , A61B2034/2065 , A61B2090/3937 , A61B2090/502 , A61B2090/571 , A61B5/11 , A61B90/36 , A61B90/361 , A61B90/50
摘要： An endoscope system having an endoscope, a scope holder holding the endoscope, a magnetic three-dimensional position sensor, and a TV monitor. The sensor detects the position of an object and generates data representing this position. According to the data, the view field of the endoscope is switched.
摘要翻译：具有内窥镜的内窥镜系统，保持内窥镜的镜架，磁性三维位置传感器和TV监视器。传感器检测物体的位置并产生表示该位置的数据。根据该数据，切换内窥镜的视野。

5. 发明授权

US07133138B2 Rapid depth scanning optical imaging device 有权
标题翻译：快速深度扫描光学成像装置
公开(公告)号：US07133138B2
公开(公告)日：2006-11-07
申请号：US10727302
申请日：2003-12-02
申请人： Akihiro Horii , Mamoru Kaneko , Tadashi Hirata , Hitoshi Mizuno
发明人： Akihiro Horii , Mamoru Kaneko , Tadashi Hirata , Hitoshi Mizuno
IPC分类号： G01B9/02
CPC分类号： G01B9/02007 , G01B9/02003 , G01B9/0201 , G01B9/0205 , G01B9/02091 , G01B2290/20 , G01B2290/35 , G01B2290/40 , G01B2290/65 , G01B2290/70
摘要： An optical imaging device includes a reference scanning unit offering a high signal-to-noise ratio and capable of scanning an object rapidly. An interference optical system can be realized inexpensively. In the optical imaging device, low coherent light passed through an optical coupler and another optical coupler, irradiated from an optical scanner probe, reflected from an observed point in a living tissue, returned to the optical coupler, propagated over a fourth SM optical fiber, and routed to another optical coupler shall be referred to as sample light. Light passed through an optical length variation optical system via the optical coupler and routed to the optical coupler shall be referred to as reference light. At this time, a difference between a delay time undergone by the sample light and a delay time undergone by the reference light is proportional to a difference between an optical length for the sample light and an optical length for the reference light. When the optical length difference falls within a coherence length, the sample light and reference light interfere with each other. An interfering signal is acquired into a computer through detectors, a differential amplifier, a demodulator, and an A/D converter.
摘要翻译：光学成像装置包括提供高信噪比并且能够快速扫描物体的参考扫描单元。可以廉价地实现干涉光学系统。在光学成像装置中，通过光耦合器和从光学扫描器探针照射的另一光耦合器的低相干光从活组织中的观察点反射回到光耦合器，在第四SM光纤上传播，并且路由到另一个光耦合器应被称为采样光。通过光学长度变化光学系统的光通过光耦合器并被路由到光耦合器的光线将被称为参考光。此时，由采样光所经历的延迟时间与参考光经历的延迟时间之间的差异与样本光的光学长度与参考光的光学长度之间的差成正比。当光学长度差落入相干长度时，样品光和参考光彼此干涉。通过检测器，差分放大器，解调器和A / D转换器将干扰信号采集到计算机中。

6. 发明授权

US07029436B2 Optical probe for producing tomogram of specimen by the use of low-coherence light 失效
公开(公告)号：US07029436B2
公开(公告)日：2006-04-18
申请号：US10095225
申请日：2002-03-08
申请人： Shuhei Iizuka , Akihiro Horii , Mamoru Kaneko , Kenji Hirooka , Hitoshi Mizuno
发明人： Shuhei Iizuka , Akihiro Horii , Mamoru Kaneko , Kenji Hirooka , Hitoshi Mizuno
IPC分类号： A61B1/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0073
摘要： On the side at hand of an optical probe, a whole rotation transfer connector rotates while being supported by a ball bearing and a slide bearing and, therefore, rotation is transferred to a flexible shaft. The relative position between the flexible shaft and an optical sheath is changed in accordance with the amount of screwing of a sheath stopping member on the side at hand into an outer cylinder by an external thread portion and an internal thread portion. When the optical sheath is moved furthermore, the flexible shaft is elongated due to elastic deformation because the length of the flexible shaft is regulated by the interval between a locking part of a locking member at the tip and a shaft stopping member. A tip housing is made to contact with the locking member while tension is applied to the flexible shaft by the rear end surface in the direction of the side at hand. During the use of optical probe, even when the optical probe is curved and the inner surface of the flexible shaft is contacted with the inner surface of the optical sheath, moving of the tip housing is canceled by the elongation amount of the flexible shaft elongated in advance and, therefore, the tip housing rotates at a constant position relative to the probe longitudinal direction on all occasions.

7. 发明授权

US06687010B1 Rapid depth scanning optical imaging device 有权
公开(公告)号：US06687010B1
公开(公告)日：2004-02-03
申请号：US09656799
申请日：2000-09-07
申请人： Akihiro Horii , Mamoru Kaneko , Tadashi Hirata , Hitoshi Mizuno
发明人： Akihiro Horii , Mamoru Kaneko , Tadashi Hirata , Hitoshi Mizuno
IPC分类号： G01B902
CPC分类号： G01B9/02007 , G01B9/02003 , G01B9/0201 , G01B9/0205 , G01B9/02091 , G01B2290/20 , G01B2290/35 , G01B2290/40 , G01B2290/65 , G01B2290/70
摘要： An optical imaging device includes a reference scanning unit offering a high signal-to-noise ratio and capable of scanning an object rapidly. An interference optical system can be realized inexpensively. In the optical imaging device, low coherent light passed through an optical coupler and another optical coupler, irradiated from an optical scanner probe, reflected from an observed point in a living tissue, returned to the optical coupler, propagated over a fourth SM optical fiber, and routed to another optical coupler shall be referred to as sample light. Light passed through an optical length variation optical system via the optical coupler and routed to the optical coupler shall be referred to as reference light. At this time, a difference between a delay time undergone by the sample light and a delay time undergone by the reference light is proportional to a difference between an optical length for the sample light and an optical length for the reference light. When the optical length difference falls within a coherence length, the sample light and reference light interfere with each other. An interfering signal is acquired into a computer through detectors, a differential amplifier, a demodulator, and an A/D converter.

8. 发明申请

US20050168751A1 Optical imaging apparatus 有权
标题翻译：光学成像装置
公开(公告)号：US20050168751A1
公开(公告)日：2005-08-04
申请号：US10874573
申请日：2004-06-24
申请人： Akihiro Horii , Hitoshi Ueno , Shuhei Iizuka , Hitoshi Mizuno , Tadashi Hirata
发明人： Akihiro Horii , Hitoshi Ueno , Shuhei Iizuka , Hitoshi Mizuno , Tadashi Hirata
IPC分类号： A61B5/00 , G01N21/47 , G01B9/02
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , G01N21/4795
摘要： An optical imaging apparatus has an optical scanning probe configured to irradiate low-coherence light onto a subject and to perform photo-reception of light scattered at the subject, and an observation device adapted to construct a cross-section image of the subject based on information from the light received through the optical scanning probe. The optical scanning probe is detachably connected to the observation device.
摘要翻译：光学成像装置具有：光学扫描探针，被配置为将低相干光照射到被摄体上并对被检体散射的光进行光接收;以及观察装置，其适于基于信息构建被检体的截面图像从通过光学扫描探测器接收的光线。光学扫描探针可拆卸地连接到观察装置。

9. 发明授权

US07180600B2 Optical imaging apparatus 有权
标题翻译：光学成像装置
公开(公告)号：US07180600B2
公开(公告)日：2007-02-20
申请号：US10874573
申请日：2004-06-24
申请人： Akihiro Horii , Hitoshi Ueno , Shuhei Iizuka , Hitoshi Mizuno , Tadashi Hirata
发明人： Akihiro Horii , Hitoshi Ueno , Shuhei Iizuka , Hitoshi Mizuno , Tadashi Hirata
IPC分类号： G01B9/02 , A61B6/00
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , G01N21/4795
摘要： An optical imaging apparatus has an optical scanning probe configured to irradiate low-coherence light onto a subject and to perform photo-reception of light scattered at the subject, and an observation device adapted to construct a cross-section image of the subject based on information from the light received through the optical scanning probe. The optical scanning probe is detachably connected to the observation device.
摘要翻译：光学成像装置具有：光学扫描探针，被配置为将低相干光照射到被摄体上并对被检体散射的光进行光接收;以及观察装置，其适于基于信息构建被检体的截面图像从通过光学扫描探测器接收的光线。光学扫描探针可拆卸地连接到观察装置。

10. 发明授权

US07129473B2 Optical image pickup apparatus for imaging living body tissue 有权
标题翻译：用于对活体组织进行成像的光学图像拾取装置
公开(公告)号：US07129473B2
公开(公告)日：2006-10-31
申请号：US10846967
申请日：2004-05-14
申请人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
发明人： Yasushige Ishihara , Atsushi Okawa , Hiroshi Tosaka , Tianyu Xie , Tadashi Hirata , Akihiro Horii , Kazunari Tokuda
IPC分类号： G01B5/28 , G02B26/08
CPC分类号： A61B1/04 , A61B1/0008 , A61B1/00096 , A61B1/00165 , A61B1/00172 , A61B1/00183 , A61B1/00188 , A61B1/07 , G02B21/0032 , G02B21/0036
摘要： A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.
摘要翻译：光学摄像装置的控制部分包括扫描驱动器，锁定放大器和A / D转换器。扫描驱动器向Y扫描镜和X扫描镜输出预定的驱动信号，扫描Y扫描镜和X扫描镜。锁定放大器在由检测器部分检测的信号中检测扫描驱动器的驱动信号的频率分量的信号电平Vout。 A / D转换器将由检测器部分检测的信号和由锁定放大器检测的驱动信号的频率分量的检测信号的信号电平转换为数字信号，并将数字信号输出到图像处理器。因此，可以可靠地检测扫描镜的镜像扫描操作。

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