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1. 发明申请

US20090111176A1 Trehalose transporter gene and method of introducing trehalose into cells 有权
标题翻译：海藻糖转运蛋白基因和将海藻糖引入细胞的方法
公开(公告)号：US20090111176A1
公开(公告)日：2009-04-30
申请号：US12073457
申请日：2008-03-05
申请人： Takahiro Kikawada , Takashi Okuda , Masahiko Watanabe , Ayako Saito , Yasushi Kanamori , Yuichi Nakahara
发明人： Takahiro Kikawada , Takashi Okuda , Masahiko Watanabe , Ayako Saito , Yasushi Kanamori , Yuichi Nakahara
IPC分类号： C12N5/06 , C12N15/11 , C07K14/00 , C12N15/00
CPC分类号： C07K14/43563 , C07K14/43577
摘要： There are provided trehalose transporter gene and a method of introducing trehalose into cells by using the gene. Candidates for the trehalose transporter genes were searched in P. vanderplanki EST, resulting in being obtained cDNA designated as Tret1. Tret1 encodes a 504 amino acid protein with 12 trans-membrane structures. Tret1 expression was induced by desiccation stress and predominant in the fat body. Functional expression of TRET1 in Xenopus oocytes showed that transport activity was specific for trehalose and independent of extracellular pH and electrochemical membrane potential. The direction of transport of TRET1 was reversible depending on the concentration gradient of trehalose. Apparent Km and Vmax of TRET1 for trehalose were extraordinarily high values. These results indicate that TRET1 is a facilitated, high-capacity trehalose-specific transporter. Tret1 is widespread in insects. Furthermore, TRET1 conferred trehalose permeability upon cells including those of vertebrates as well as insects.
摘要翻译：提供海藻糖转运蛋白基因和通过使用该基因将海藻糖引入细胞的方法。在P. vanderplanki EST中搜索海藻糖转运蛋白基因的候选物，得到获得的命名为Tret1的cDNA。 Tret1编码具有12个跨膜结构的504个氨基酸的蛋白质。 Tret1表达由干燥应激诱导，在脂肪体中占优势。非洲爪蟾卵母细胞中TRET1的功能表达显示，转运活性对海藻糖是特异性的，独立于细胞外pH和电化学膜电位。根据海藻糖的浓度梯度，TRET1的转运方向是可逆的。 TRET1对于海藻糖的表观Km和Vmax是非常高的值。这些结果表明TRET1是一种促进的高容量海藻糖特异性转运蛋白。 Tret1在昆虫中广泛存在。此外，TRET1在包括脊椎动物以及昆虫的细胞中赋予海藻糖通透性。

2. 发明授权

US07892789B2 Method of increasing cell permeability to trehalose by recombinantly producing a trehalose transporter 有权
标题翻译：通过重组产生海藻糖转运蛋白增加海藻糖的细胞渗透性的方法
公开(公告)号：US07892789B2
公开(公告)日：2011-02-22
申请号：US12073457
申请日：2008-03-05
申请人： Takahiro Kikawada , Takashi Okuda , Masahiko Watanabe , Ayako Saito , Yasushi Kanamori , Yuichi Nakahara
发明人： Takahiro Kikawada , Takashi Okuda , Masahiko Watanabe , Ayako Saito , Yasushi Kanamori , Yuichi Nakahara
IPC分类号： C12P21/06
CPC分类号： C07K14/43563 , C07K14/43577
摘要： There are provided trehalose transporter gene and a method of introducing trehalose into cells by using the gene. Candidates for the trehalose transporter genes were searched in P. vanderplanki EST, resulting in being obtained cDNA designated as Tret1. Tret1 encodes a 504 amino acid protein with 12 trans-membrane structures. Tret1 expression was induced by desiccation stress and predominant in the fat body. Functional expression of TRET1 in Xenopus oocytes showed that transport activity was specific for trehalose and independent of extracellular pH and electrochemical membrane potential. The direction of transport of TRET1 was reversible depending on the concentration gradient of trehalose. Apparent Km and Vmax of TRET1 for trehalose were extraordinarily high values. These results indicate that TRET1 is a facilitated, high-capacity trehalose-specific transporter. Tret1 is widespread in insects. Furthermore, TRET1 conferred trehalose permeability upon cells including those of vertebrates as well as insects.
摘要翻译：提供海藻糖转运蛋白基因和通过使用该基因将海藻糖引入细胞的方法。在P. vanderplanki EST中搜索海藻糖转运蛋白基因的候选物，得到获得的命名为Tret1的cDNA。 Tret1编码具有12个跨膜结构的504个氨基酸的蛋白质。 Tret1表达由干燥应激诱导，在脂肪体中占优势。非洲爪蟾卵母细胞中TRET1的功能表达显示，转运活性对海藻糖是特异性的，独立于细胞外pH和电化学膜电位。根据海藻糖的浓度梯度，TRET1的转运方向是可逆的。 TRET1对于海藻糖的表观Km和Vmax是非常高的值。这些结果表明TRET1是一种促进的高容量海藻糖特异性转运蛋白。 Tret1在昆虫中广泛存在。此外，TRET1在包括脊椎动物以及昆虫的细胞中赋予海藻糖通透性。

3. 发明授权

US06387552B1 TiCN-based cermet 失效
标题翻译： TiCN基金属陶瓷
公开(公告)号：US06387552B1
公开(公告)日：2002-05-14
申请号：US09666538
申请日：2000-09-21
申请人： Yusuke Iyori , Yuichi Nakahara , Yoshio Kimura
发明人： Yusuke Iyori , Yuichi Nakahara , Yoshio Kimura
IPC分类号： B32B5102
CPC分类号： C22C29/04 , Y10T428/252
摘要： A TiCN-based cermet comprises 5-25 weight % of a binder phase mainly composed of Co and/or Ni, the balance being substantially a hard phase and inevitable impurities, the hard phase being mainly composed of carbide, nitride and/or carbonitride and containing at least Ti and W, the cermet having a cross-section microstructure in which the number of Ti-rich particles having an area of 0.02 &mgr;m2 or more is 1000 or less per a unit area of 1000 &mgr;m2.
摘要翻译：基于TiCN的金属陶瓷包括5-25重量％的主要由Co和/或Ni组成的粘结相，余量基本上是硬相和不可避免的杂质，硬相主要由碳化物，氮化物和/或碳氮化物组成，含有至少Ti和W的金属陶瓷具有横截面微观结构，其中面积为0.02mum2以上的富钛颗粒的数量为1000mum2的单位面积为1000以下。

4. 发明申请

US20130190078A1 RELAY DEVICE AND GAME SYSTEM 审中-公开
标题翻译：继电器和游戏系统
公开(公告)号：US20130190078A1
公开(公告)日：2013-07-25
申请号：US13876647
申请日：2011-12-20
申请人： Nobuhiro Goto , Tetsuo Ishida , Jun Komatsu , Yuichi Nakahara , Teruhiko Kimura
发明人： Nobuhiro Goto , Tetsuo Ishida , Jun Komatsu , Yuichi Nakahara , Teruhiko Kimura
IPC分类号： G07F17/32
CPC分类号： G07F17/3248 , G07F17/3225 , G07F17/3258
摘要： A relay device connected to a game device receives an increase instruction for increasing a credit number via a communication unit that communicates with an outside, and stores the credit number to be increased. The relay device generates pseudo medal detection pulses, and supplies medal detection pulses obtained by a logical sum between normal medal detection pulses that are generated in the game device and the pseudo medal detection pulses to a game device. When receiving the increase instruction, the relay device generates a pseudo discharge signal that gives an instruction to discharge medals inserted in the game device out of the device, and supplies a discharge signal obtained by a logical sum between a normal discharge signal that is generated in the game device and the pseudo discharge signal to the game device. After the pseudo discharge signal is generated, the relay device generates the pseudo medal detection pulses, whose number corresponds to the credit number stored in a storage unit.
摘要翻译：连接到游戏装置的中继装置经由与外部通信的通信单元接收用于增加信用号的增加指示，并存储要增加的信用号。中继装置生成伪奖牌检测脉冲，并且将通过在游戏装置中生成的正常奖牌检测脉冲和伪奖牌检测脉冲之间的逻辑和获得的奖牌检测脉冲提供给游戏装置。当接收到增加指令时，继电器装置产生伪放电信号，该伪放电信号指示将从游戏装置插入的装置中的奖牌放出装置，并且通过逻辑和获得的放电信号，游戏装置和伪放电信号发送到游戏装置。在产生伪放电信号之后，中继装置产生伪存储体检测脉冲，其数量对应于存储在存储单元中的信用号。

5. 发明申请

US20120040415A1 METHOD FOR PRODUCING AN L-AMINO ACID 审中-公开
标题翻译：生产L-氨基酸的方法
公开(公告)号：US20120040415A1
公开(公告)日：2012-02-16
申请号：US13170661
申请日：2011-06-28
申请人： Yuichi Nakahara , Yusuke Hagiwara , Yuri Nagai , Takuji Ueda , Kazuyuki Hayashi , Yuki Yano
发明人： Yuichi Nakahara , Yusuke Hagiwara , Yuri Nagai , Takuji Ueda , Kazuyuki Hayashi , Yuki Yano
IPC分类号： C12P13/08 , C12P13/04
CPC分类号： C12P13/08 , C12P13/04
摘要： A method is provided for producing an L-amino acid which includes the steps of culturing a bacterium, which belongs to the family Enterobacteriaceae and is able to produce an L-amino acid, in a medium containing glycerol as a carbon source to produce and accumulate an L-amino acid in the medium, and collecting the L-amino acid from the culture. The culture is performed as a fed-batch culture or a continuous culture, and a feed medium containing glycerol is added to the fermentation medium so that the glycerol concentration in the fermentation medium is 5 g/L or higher.
摘要翻译：提供了一种生产L-氨基酸的方法，其包括在含有甘油作为碳源的培养基中培养属于肠杆菌科并能够产生L-氨基酸的细菌以产生和积累的步骤培养基中的L-氨基酸，并从培养物中收集L-氨基酸。作为补料分批培养或连续培养进行培养，向发酵培养基中添加含有甘油的饲料培养基，发酵培养基中的甘油浓度为5g / L以上。

6. 发明授权

US08221235B2 Drawing machine and game apparatus using the same 有权
标题翻译：绘图机和游戏机使用相同
公开(公告)号：US08221235B2
公开(公告)日：2012-07-17
申请号：US12084328
申请日：2006-10-27
申请人： Nobuhiro Goto , Kazuhiro Kusuda , Daisuke Sato , Shingo Yasuda , Yuichi Nakahara
发明人： Nobuhiro Goto , Kazuhiro Kusuda , Daisuke Sato , Shingo Yasuda , Yuichi Nakahara
IPC分类号： A63F9/24
CPC分类号： G07F17/3276 , G07F17/32 , G07F17/3286
摘要： The present invention provides a drawing machine and a game apparatus using the same by which it is easier to give the participants of the drawing an impression like drawing is carried out fairly when the computer drawing in which a winning-probability of each of drawing-objects is changed is carried out.A drawing machine for determining a winning-object from a plurality of drawing-objects includes: a winning-probability data storage unit for storing winning-probability data showing respective winning-probabilities of the plurality of drawing-objects; a drawing unit for carrying out a drawing in accordance with the winning-probability of each of the drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit and determining a winning-object from the plurality of drawing-objects; a winning-probability data changing unit for changing the winning-probability data stored in the winning-probability data storage unit; a winning-probability image displaying unit for displaying a winning-probability image showing the winning-probability of each of the drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit; and a winning-probability displaying control unit for changing the winning-probability image displayed on the winning-probability image displaying unit, when the winning-probability data changing unit changes the winning-probability data, so as to correspond to the changed winning-probability data.
摘要翻译：本发明提供了一种绘图机和使用该绘图机的游戏装置，其中当每个绘图对象的获胜概率的计算机绘图时，更容易给予绘图的参与者像绘图的印象被改变了。用于从多个绘图对象确定获胜对象的绘图机包括：获胜概率数据存储单元，用于存储显示多个绘图对象的各个获胜概率的获胜概率数据; 绘制单元，用于根据存储在获胜概率数据存储单元中的获胜概率数据确定的每个绘制对象的获胜概率执行绘图，并从多个绘制单元确定获胜对象，物体获胜概率数据改变单元，用于改变存储在获胜概率数据存储单元中的获胜概率数据; 获胜概率图像显示单元，用于显示表示由获胜概率数据存储单元中存储的获胜概率数据确定的每个绘图对象的获胜概率的获胜概率图像; 以及获胜概率显示控制单元，用于当获胜概率数据改变单元改变获胜概率数据时，改变在获胜概率图像显示单元上显示的获胜概率图像，以便对应于改变的获胜概率数据。

7. 发明申请

US20090264175A1 Drawing Machine and Game Apparatus Using the Same 审中-公开
标题翻译：绘图机和使用它的游戏装置
公开(公告)号：US20090264175A1
公开(公告)日：2009-10-22
申请号：US12084327
申请日：2006-10-27
申请人： Nobuhiro Goto , Kazuhiro Kusuda , Yuichi Nakahara , Daisuke Sato , Monju Wada
发明人： Nobuhiro Goto , Kazuhiro Kusuda , Yuichi Nakahara , Daisuke Sato , Monju Wada
IPC分类号： A63F9/24
CPC分类号： G07F17/32 , G07F17/323
摘要： The present invention provides a drawing machine and a game apparatus using the same by which participants of drawing can intervene in a process of drawing.A drawing machine for determining a winning-object from a plurality of drawing-objects includes: a winning-probability data storage unit for storing winning-probability data showing respective winning-probabilities of the plurality of drawing-objects; a drawing unit for carrying out drawings in accordance with the winning-probabilities of the respective drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit and determining the winning-object from the plurality of drawing-objects; an operation unit operated by a participant of the drawing; a desired drawing-object determination unit for determining a desired drawing-object which the participant of drawing desires to win or not win, from the plurality of drawing-objects based on an operation of the operation unit; and a winning-probability data changing unit for changing the winning-probability data stored in the winning-probability data storage unit so that a winning-probability of the desired drawing-object determined by the desired drawing-object determination unit is changed.
摘要翻译：本发明提供一种拉丝机和使用该拉丝机的游戏装置，通过该装置，绘图参与者可以介入绘图过程。用于从多个绘图对象确定获胜对象的绘图机包括：获胜概率数据存储单元，用于存储显示多个绘图对象的各个获胜概率的获胜概率数据; 绘制单元，用于根据存储在获胜概率数据存储单元中的获胜概率数据确定的各个绘图对象的获胜概率进行绘图，并从多个绘图对象中确定获胜对象; 由图纸参与者操作的操作单元; 基于操作单元的操作从所述多个绘图对象中确定所述绘图参与者想要赢得或不赢的期望绘图对象确定单元; 以及获胜概率数据改变单元，用于改变存储在获胜概率数据存储单元中的获胜概率数据，使得由期望的绘图对象确定单元确定的期望绘图对象的获胜概率改变。

8. 发明申请

US20100173706A1 IMAGE DISPLAY CONTROL DEVICE, GAME APPARATUS, AND PROGRAM AND RECORDING MEDIUM HAVING THE SAME 审中-公开
标题翻译：图像显示控制装置，游戏装置以及具有该图像的程序和记录介质
公开(公告)号：US20100173706A1
公开(公告)日：2010-07-08
申请号：US12663024
申请日：2008-06-02
申请人： Yuichi Nakahara , Kotaro Matsumura , Daisuke Sato , Yoshitaka Tamura , Shinya Ito
发明人： Yuichi Nakahara , Kotaro Matsumura , Daisuke Sato , Yoshitaka Tamura , Shinya Ito
IPC分类号： A63F13/00 , A63F9/24
CPC分类号： A63F13/52 , A63F13/10 , A63F2300/203 , A63F2300/6653 , G06T15/50 , G06T2210/62
摘要： The present invention provides an image display control device, etc., capable of preventing a specific object, which is required not to be seen by the user when the specific object is positioned outside a visible field, among various objects located in a virtual field from being seen by the user in an easy method when the specific object is positioned outside the visible field.An image display control device comprises: an image information storage unit for storing image information necessary for displaying, at a display unit, an image of various objects located in a virtual field constituted of a two-dimensional virtual plane or a three-dimensional virtual space; a location decision unit for deciding location of various objects in the virtual field; and a display control unit for executing display control to display, at the display unit, the image of the object located in a visible field, which is a part of the virtual field, in a state where the visible field is viewed from a predetermined viewpoint direction, based on location of the objects decided by the location decision unit and image information stored in the image information storage unit, a transparentizing process for transparentizing an image of a specific object located in the virtual field by the location decision unit when the specific object is positioned at least in an adjacent field adjacent to the visible field on the outside of the visible field, and an opacifying process for opacifying an image of the specific object when the specific object is positioned inside the visible field.
摘要翻译：本发明提供一种图像显示控制装置等，能够防止特定对象在特定对象位于可视场外部时被用户看不到，特定对象位于虚拟场中的各种对象中当特定对象位于可见字段之外时，用户可以通过简单的方法看到它。图像显示控制装置包括：图像信息存储单元，用于存储在显示单元处显示位于由二维虚拟平面或三维虚拟空间构成的虚拟场中的各种对象的图像所需的图像信息 ; 位置决定单元，用于确定虚拟场中的各种物体的位置; 以及显示控制单元，用于执行显示控制，以在从所述显示单元在从预定视点观看所述可视场的状态下显示位于所述虚拟场的一部分的可视区域中的对象的图像方向，基于由位置决定单元确定的对象的位置和存储在图像信息存储单元中的图像信息，透明化处理，用于当特定对象由位置决定单元透明位于虚拟场中的特定对象的图像时至少位于与可视场外侧的可视场相邻的相邻场中，以及当特定物体位于可见场内时，使不透明的特定物体的图像不透明化的过程。

9. 发明授权

US5468278A Cermet alloy 失效
标题翻译：金属陶瓷合金
公开(公告)号：US5468278A
公开(公告)日：1995-11-21
申请号：US149939
申请日：1993-11-10
申请人： Yuichi Nakahara , Katsuhiko Kojo
发明人： Yuichi Nakahara , Katsuhiko Kojo
IPC分类号： C22C29/02 , C22C29/00
CPC分类号： C22C29/02
摘要： This invention provides a cermet alloy having a structure comprising a hard phase and a bonding phase, wherein the hard phase comprising carbide particles rich An TiC, those rich in WC and (Ti, W, MO)C or (Ti, W, Mo)(C, N) and the bonding phase comprising at least one of Co and Ni. Mo contents in the bonding phase satisfies the conditions: 1.0.ltoreq.Mo (wt %)/Ti (wt %) and 6 (wt %).ltoreq.Ti+Mo. The cermet alloy has superior hardness and toughness as well as improved heat resistance and is applicable as a material for a wet machining tool.
摘要翻译：本发明提供一种具有包含硬质相和结合相的结构的金属陶瓷合金，其中，包含富Ti的碳化物颗粒，WC和（Ti，W，MO）C或（Ti，W，Mo）（C，N）和包含Co和Ni中的至少一种的结合相。粘结相中的Mo含量满足条件：1.0

10. 发明申请

US20090247260A1 Drawing Machine and Game Apparatus Using the Same 有权
标题翻译：绘图机和使用它的游戏装置
公开(公告)号：US20090247260A1
公开(公告)日：2009-10-01
申请号：US12084328
申请日：2006-10-27
申请人： Nobuhiro Goto , Kazuhiro kusuda , Daisuki Sato , Shingo Yasuda , Yuichi Nakahara
发明人： Nobuhiro Goto , Kazuhiro kusuda , Daisuki Sato , Shingo Yasuda , Yuichi Nakahara
IPC分类号： A63F9/24 , A63F13/00
CPC分类号： G07F17/3276 , G07F17/32 , G07F17/3286
摘要： The present invention provides a drawing machine and a game apparatus using the same by which it is easier to give the participants of the drawing an impression like drawing is carried out fairly when the computer drawing in which a winning-probability of each of drawing-objects is changed is carried out.A drawing machine for determining a winning-object from a plurality of drawing-objects includes: a winning-probability data storage unit for storing winning-probability data showing respective winning-probabilities of the plurality of drawing-objects; a drawing unit for carrying out a drawing in accordance with the winning-probability of each of the drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit and determining a winning-object from the plurality of drawing-objects; a winning-probability data changing unit for changing the winning-probability data stored in the winning-probability data storage unit; a winning-probability image displaying unit for displaying a winning-probability image showing the winning-probability of each of the drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit; and a winning-probability displaying control unit for changing the winning-probability image displayed on the winning-probability image displaying unit, when the winning-probability data changing unit changes the winning-probability data, so as to correspond to the changed winning-probability data.
摘要翻译：本发明提供了一种绘图机和使用该绘图机的游戏装置，其中当每个绘图对象的获胜概率的计算机绘图时，更容易给予绘图的参与者像绘图的印象进行了改变。用于从多个绘图对象确定获胜对象的绘图机包括：获胜概率数据存储单元，用于存储显示多个绘图对象的各个获胜概率的获胜概率数据; 绘制单元，用于根据存储在获胜概率数据存储单元中的获胜概率数据确定的每个绘制对象的获胜概率执行绘图，并从多个绘制单元确定获胜对象，物体获胜概率数据改变单元，用于改变存储在获胜概率数据存储单元中的获胜概率数据; 获胜概率图像显示单元，用于显示表示由获胜概率数据存储单元中存储的获胜概率数据确定的每个绘图对象的获胜概率的获胜概率图像; 以及获胜概率显示控制单元，用于当获胜概率数据改变单元改变获胜概率数据时，改变在获胜概率图像显示单元上显示的获胜概率图像，以便对应于改变的获胜概率数据。

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