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    • 4. 发明授权
    • Systems and methods for delivering substances into nanoporous mineralized tissues
    • 将物质输送到纳米多孔矿化组织中的系统和方法
    • US08905759B2
    • 2014-12-09
    • US13492090
    • 2012-06-08
    • Hiongyap GanJongyoon HanFrederico Barbosa de Sousa
    • Hiongyap GanJongyoon HanFrederico Barbosa de Sousa
    • A61C5/00A61C19/06A61N1/05A61N1/30
    • A61C19/066A61N1/0548A61N1/306
    • Methods and systems are provided for transporting a therapeutic or cosmetic substance into nanoporous mineralized tissue structures, such as teeth. The method may include contacting the nanoporous mineralized tissue structure with an ionic solution including the therapeutic or cosmetic substance; and simultaneously applying to the nanoporous mineralized tissue structure an electrical potential effective to transport the therapeutic or cosmetic substance into the nanopores of the nanoporous mineralized tissue structure. The system may include at least one pair of electrodes which includes a first electrode configured for contacting the nanoporous mineralized tissue structure and a second electrode; and a power source and control circuitry for generating an electrical potential between the first electrode and the second electrode effective to transport a therapeutic or cosmetic substance, in an ionic solution in contact with a surface of the nanoporous mineralized tissue structure, into the nanopores of the nanoporous mineralized tissue structure.
    • 提供了用于将治疗或化妆物质运输到纳米多孔矿化组织结构(如牙齿)中的方法和系统。 该方法可包括使纳米多孔矿化组织结构与包含治疗或化妆物质的离子溶液接触; 并且同时向纳米多孔矿化组织结构施加有效地将治疗或化妆物质输送到纳米多孔矿化组织结构的纳米孔中的电势。 该系统可以包括至少一对电极,其包括构造成用于接触纳米多孔矿化组织结构和第二电极的第一电极; 以及用于在第一电极和第二电极之间产生电位的电源和控制电路,其有效地将治疗或化妆品物质在与纳米多孔矿化组织结构的表面接触的离子溶液中输送到纳米孔的纳米孔中 纳米多孔矿化组织结构。
    • 5. 发明申请
    • SYSTEMS AND METHODS FOR DELIVERING SUBSTANCES INTO NANOPOROUS MINERALIZED TISSUES
    • 将物质输送到纳米矿物组织的系统和方法
    • US20120315596A1
    • 2012-12-13
    • US13492090
    • 2012-06-08
    • Hiongyap GanJongyoon HanFrederico Barbosa de Sousa
    • Hiongyap GanJongyoon HanFrederico Barbosa de Sousa
    • A61C19/06
    • A61C19/066A61N1/0548A61N1/306
    • Methods and systems are provided for transporting a therapeutic or cosmetic substance into nanoporous mineralized tissue structures, such as teeth. The method may include contacting the nanoporous mineralized tissue structure with an ionic solution including the therapeutic or cosmetic substance; and simultaneously applying to the nanoporous mineralized tissue structure an electrical potential effective to transport the therapeutic or cosmetic substance into the nanopores of the nanoporous mineralized tissue structure. The system may include at least one pair of electrodes which includes a first electrode configured for contacting the nanoporous mineralized tissue structure and a second electrode; and a power source and control circuitry for generating an electrical potential between the first electrode and the second electrode effective to transport a therapeutic or cosmetic substance, in an ionic solution in contact with a surface of the nanoporous mineralized tissue structure, into the nanopores of the nanoporous mineralized tissue structure.
    • 提供了用于将治疗或化妆物质运输到纳米多孔矿化组织结构(如牙齿)中的方法和系统。 该方法可包括使纳米多孔矿化组织结构与包含治疗或化妆物质的离子溶液接触; 并且同时向纳米多孔矿化组织结构施加有效地将治疗或化妆物质输送到纳米多孔矿化组织结构的纳米孔中的电势。 该系统可以包括至少一对电极,其包括构造成用于接触纳米多孔矿化组织结构和第二电极的第一电极; 以及用于在第一电极和第二电极之间产生电位的电源和控制电路,其有效地将治疗或化妆品物质在与纳米多孔矿化组织结构的表面接触的离子溶液中输送到纳米孔的纳米孔中 纳米多孔矿化组织结构。