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1. 发明授权

US08974422B2 Neurological apparatus comprising a percutaneous access device 有权
标题翻译：包括经皮进入装置的神经病学装置
公开(公告)号：US08974422B2
公开(公告)日：2015-03-10
申请号：US12312584
申请日：2007-11-21
申请人： Steven Streatfield Gill , Paul David Fielder
发明人： Steven Streatfield Gill , Paul David Fielder
IPC分类号： A61M5/32 , A61M39/02
CPC分类号： A61M39/0247 , A61M2039/025 , A61M2039/0264 , A61M2039/0276 , A61M2039/0282 , A61M2039/0285 , A61M2039/0291 , A61M2210/0693
摘要： Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus comprises at least one intracranial catheter and a percutaneous access device. The percutaneous access device comprises a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described.
摘要翻译：描述了将治疗剂递送到受试者的中枢神经系统的装置。该装置包括至少一个颅内导管和经皮进入装置。经皮进入装置包括具有至少一个体外表面和至少一个皮下表面的主体，该主体限定用于连接到植入的颅内导管的至少一个端口。该端口可从装置的体外表面接近，但是在端口的内腔和体外表面之间设置有诸如橡胶塞之类的密封件。经皮进入装置可具有多于两个的端口和/或凸缘。还描述了植入经皮进入装置的方法。

2. 发明申请

US20110009879A1 APPARATUS FOR STEREOTACTIC NEUROSURGERY 审中-公开
标题翻译：装置神经外科手术
公开(公告)号：US20110009879A1
公开(公告)日：2011-01-13
申请号：US12733562
申请日：2008-10-06
申请人： Hugo George Derrick , Paul David Fielder , Steven Streatfield Gill
发明人： Hugo George Derrick , Paul David Fielder , Steven Streatfield Gill
IPC分类号： A61B19/00
CPC分类号： A61B17/3403 , A61B17/3415 , A61B17/3423 , A61B90/11 , A61B2017/3407 , A61B2090/103
摘要： A skull mount (50;150;170;200;300) is described that is attachable to a hole (60) formed in the skull. The skull mount (50;150;170;200;300) comprises an alignment guide (62;152;172;216;306) defining an alignment axis (22;210;312) along which neurosurgical instruments can be passed. The skull mount, when attached to a hole in a skull, is arranged such that it does not substantially protrude from the outermost surface of the skull and does not extend into the brain parenchyma. Also described is a neurosurgical alignment instrument (30,206) for aligning such a skull mount (50;150;170;200;300) that comprises an elongate shaft (32) and an element (34,36) protruding from the distal end of the elongate shaft (32) for engaging and aligning the alignment guide (62;152;172;216;306) of an associated skull mount (50;150;170;200;300). When the alignment instrument is engaged with a skull mount attached to a hole formed in the skull, the protruding element passes through the alignment guide of the skull mount and into the cortex of the subject's brain.
摘要翻译：描述了可附接到形成在颅骨中的孔（60）的颅骨支座（50; 150; 170; 200; 300）。颅骨支架（50; 150; 170; 200; 300）包括限定可以通过神经外科器械的对准轴线（22; 210; 312）的对准引导件（62; 152; 172; 216; 306）颅骨安装件当附着在颅骨中的孔时被布置成使得其不会从颅骨的最外表面突出并且不延伸到脑实质中。还描述了一种用于对准这样的颅骨支架（50; 150; 170; 200; 300）的神经外科对准仪器（30,206），其包括细长轴（32）和从所述头部远端突出的元件（34,36）细长轴（32），用于接合和对准相关联的颅骨支架（50; 150; 170; 200; 300）的对准引导件（62; 152; 172; 216; 306）。当对准仪器与附接到形成在颅骨中的孔的颅骨支架接合时，突出元件穿过颅骨支架的对准引导件并进入受试者大脑的皮层。

3. 发明申请

US20100042070A1 NEUROLOGICAL APPARATUS COMPRISING A PERCUTANEOUS ACCESS DEVICE 有权
标题翻译：包含PERCUTANEUSUS访问设备的神经病学设备
公开(公告)号：US20100042070A1
公开(公告)日：2010-02-18
申请号：US12312584
申请日：2007-11-21
申请人： Steven Streatfield Gill , Paul David Fielder
发明人： Steven Streatfield Gill , Paul David Fielder
IPC分类号： A61M5/142 , A61M25/00
CPC分类号： A61M39/0247 , A61M2039/025 , A61M2039/0264 , A61M2039/0276 , A61M2039/0282 , A61M2039/0285 , A61M2039/0291 , A61M2210/0693
摘要： Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus comprises at least one intracranial catheter and a percutaneous access device. The percutaneous access device comprises a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described.
摘要翻译：描述了将治疗剂递送到受试者的中枢神经系统的装置。该装置包括至少一个颅内导管和经皮进入装置。经皮进入装置包括具有至少一个体外表面和至少一个皮下表面的主体，该主体限定用于连接到植入的颅内导管的至少一个端口。该端口可从装置的体外表面接近，但是在端口的内腔和体外表面之间设置有诸如橡胶塞之类的密封件。经皮进入装置可具有多于两个的端口和/或凸缘。还描述了植入经皮进入装置的方法。

4. 发明授权

US08442653B2 Brain electrode 有权
标题翻译：脑电极
公开(公告)号：US08442653B2
公开(公告)日：2013-05-14
申请号：US13019670
申请日：2011-02-02
申请人： Steven Streatfield Gill
发明人： Steven Streatfield Gill
IPC分类号： A61N1/375
CPC分类号： A61N1/0534 , Y10T29/49224
摘要： An electrode, in particular a deep brain stimulating (DBS) electrode or a deep brain lesioning electrode, a method for manufacturing an electrode and use of the electrode, and a directional electrode.
摘要翻译：电极，特别是深部脑刺激（DBS）电极或深部脑损伤电极，电极的制造方法和电极的使用以及定向电极。

5. 发明申请

US20090030373A1 Method and Apparatus for Fluid Delivery 失效
标题翻译：流体输送方法和装置
公开(公告)号：US20090030373A1
公开(公告)日：2009-01-29
申请号：US12224655
申请日：2007-03-12
申请人： Steven Streatfield Gill
发明人： Steven Streatfield Gill
IPC分类号： A61M5/00
CPC分类号： A61M39/0208 , A61M5/14 , A61M5/1408 , A61M5/142 , A61M5/14244 , A61M39/0247 , A61M39/10 , A61M2039/0205 , A61M2039/0229 , A61M2039/0232 , A61M2039/025 , A61M2039/1066 , A61M2205/04 , A61M2210/0693
摘要： Fluid delivery apparatus is described for the delivery of fluids to regions of the body, especially for delivery to regions of the brain. The apparatus includes a first length of implantable tubing having a first end and a first fluid connector portion attached to the first end of the first length of implantable tubing. The first fluid connector portion is releaseably connectable to a complementary second fluid connector portion. An implantable housing is also provided for enclosing and protecting the first fluid connector portion. The implantable housing is openable to provide access to the first fluid connector portion. For example, the housing may have a hinged lid or cover portion. A corresponding method is also described.
摘要翻译：流体输送装置被描述为用于将流体输送到身体的区域，特别是用于输送到脑的区域。该装置包括第一长度的可植入管，其具有连接到第一长度可植入管的第一端的第一端和第一流体连接器部分。第一流体连接器部分可释放地连接到互补的第二流体连接器部分。还提供可植入外壳以封闭和保护第一流体连接器部分。可植入外壳可打开以提供对第一流体连接器部分的通路。例如，壳体可以具有铰接盖或盖部分。还描述了相应的方法。

6. 发明申请

US20130279784A1 METHOD AND APPARATUS FOR ANALYSING IMAGES 有权
标题翻译：用于分析图像的方法和装置
公开(公告)号：US20130279784A1
公开(公告)日：2013-10-24
申请号：US13994459
申请日：2011-12-21
申请人： Steven Streatfield Gill , Jian-Kun Shen
发明人： Steven Streatfield Gill , Jian-Kun Shen
IPC分类号： G06T7/00
CPC分类号： A61B90/37 , A61B6/032 , A61B6/501 , A61B34/20 , A61B34/30 , A61B90/39 , A61B2017/00694 , A61B2034/107 , A61B2034/2065 , A61B2034/303 , A61B2090/363 , A61B2090/364 , A61B2090/374 , A61B2090/3762 , A61B2090/3966 , A61B2090/3983 , A61G13/00 , G06T7/0014 , G06T7/337 , G06T7/74 , G06T2200/04 , G06T2207/10081 , G06T2207/30016 , G06T2207/30101 , G06T2210/41
摘要： A method is described for determining brain shift, such as the brain shift that occurs following a neurosurgical intervention. The method includes taking a first image of the brain of a subject, the first image showing the position of blood vessels in the brain relative to a reference position. A second image of the brain that has been acquired following an intervention on the subject is also taken. This second image has been acquired using computed tomography imaging apparatus. The second image shows the position of blood vessels in the brain relative to the reference position. Brain shift is then determined from the shift in position of the blood vessels in at least one region of interest of the brain, with respect to the reference position, between the first and second images. Corresponding apparatus is also described.
摘要翻译：描述了一种用于确定脑移位的方法，例如在神经外科手术后发生的脑移位。该方法包括拍摄对象的大脑的第一图像，第一图像显示相对于参考位置的脑中的血管的位置。还采取干预措施后获得的大脑的第二张图像。该第二图像已经使用计算机断层摄影成像装置获得。第二个图像显示大脑相对于参考位置的血管位置。然后，从第一和第二图像之间相对于参考位置的大脑的至少一个感兴趣区域中的血管位置的移位来确定脑移位。还描述了相应的装置。

7. 发明申请

US20110131808A1 BRAIN ELECTRODE 有权
标题翻译：脑电极
公开(公告)号：US20110131808A1
公开(公告)日：2011-06-09
申请号：US13019670
申请日：2011-02-02
申请人： Steven Streatfield Gill
发明人： Steven Streatfield Gill
IPC分类号： H01R43/00
CPC分类号： A61N1/0534 , Y10T29/49224
摘要： An electrode, in particular a deep brain stimulating (DBS) electrode or a deep brain lesioning electrode, a method for manufacturing an electrode and use of the electrode, and a directional electrode.
摘要翻译：电极，特别是深部脑刺激（DBS）电极或深部脑损伤电极，电极的制造方法和电极的使用以及定向电极。

8. 发明授权

US07351239B2 Implantable drug delivery pump 失效
标题翻译：可植入药物输送泵
公开(公告)号：US07351239B2
公开(公告)日：2008-04-01
申请号：US11698571
申请日：2007-01-26
申请人： Steven Streatfield Gill
发明人： Steven Streatfield Gill
IPC分类号： A61K9/22 , A61M31/00
CPC分类号： A61M5/14276 , A61M5/14232 , A61M2209/045 , A61M2210/0693
摘要： The pump includes a metering pump including a rotor, at least two lengths of tubing against which the rotor is movable to urge the drug therethrough, and an outlet port associated with each of the at least two lengths of tubing. In this way, a drug may be supplied to more than one neurological target.
摘要翻译：所述泵包括计量泵，所述计量泵包括转子，所述至少两个长度的管，所述转子可通过所述至少两个长度段移动以推动所述药物通过其中;以及出口与所述至少两个管段中的每一个相关联。以这种方式，可以向多于一个的神经系统靶标提供药物。

9. 发明授权

US07329262B2 Stereoguide for clamping neurosurgical instruments 失效
标题翻译：用于夹紧神经外科器械的立体声
公开(公告)号：US07329262B2
公开(公告)日：2008-02-12
申请号：US10507360
申请日：2003-03-11
申请人： Steven Streatfield Gill
发明人： Steven Streatfield Gill
IPC分类号： A61F5/00 , A61B19/00 , A61B1/00 , A61B5/04 , A61B18/14 , A61M5/00
CPC分类号： A61B90/11
摘要： The present invention relates to apparatus for use in neurosurgery, and to a method of positioning neurosurgical apparatus. The stereoguide comprises first and second guide elements through which instruments are passed along an axis of insertion towards a target and a first clamp (25) having a clamping position on the axis between the guide elements and the target.
摘要翻译：神经外科手术装置技术领域本发明涉及神经外科手术装置以及神经外科装置的定位方法。立体视图包括第一和第二引导元件，仪器通过该导向元件沿着插入轴线朝向目标物通过;以及第一夹具（25），其在引导元件和靶之间的轴线上具有夹紧位置。

10. 发明授权

US06355049B1 Head fixation apparatus 失效
标题翻译：头部固定装置
公开(公告)号：US06355049B1
公开(公告)日：2002-03-12
申请号：US09489580
申请日：2000-01-21
申请人： Steven Streatfield Gill
发明人： Steven Streatfield Gill
IPC分类号： A61B1900
CPC分类号： A61B90/14
摘要： A Head fixation apparatus includes a frame and a fixation structure for repeatably and reproducibily fixing the frame to a patient's head such that locations within the head are spatially definable with reference to frame. The fixation structure includes a cast of the patient's upper teeth and/or palate. The fixation structure further includes a support for rigidly connecting the cast to the frame and biasing structure operable between the head and the frame and/or the fixation structure to bias the cast into positive contact with the upper teeth and/or palate. The apparatus is used in stereotatic diagnosis and treatment.
摘要翻译：头部固定装置包括框架和固定结构，用于将框架重复地和可重复地固定到患者的头部，使得头部内的位置可以参考框架被空间定义。该固定结构包括患者上牙和/或上腭的铸件。固定结构还包括用于将铸件刚性地连接到框架的支撑件和可操作于头部和框架和/或固定结构之间的偏置结构，以将铸件偏置成与上牙和/或上颚的正接触。该仪器用于立体诊断和治疗。

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