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1. 发明申请

US20070219464A1 Guidewire with deflectable re-entry tip 审中-公开
标题翻译：导丝具有可偏转的再入口尖端
公开(公告)号：US20070219464A1
公开(公告)日：2007-09-20
申请号：US11590537
申请日：2006-10-31
申请人： Stephen Davis , David Grewe , Hikmat Hojeibane , Steven Omiecinski
发明人： Stephen Davis , David Grewe , Hikmat Hojeibane , Steven Omiecinski
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61B2017/22044 , A61B2017/22095 , A61M25/0045 , A61M25/0138 , A61M25/0147 , A61M25/0152 , A61M25/09033 , A61M2025/0042 , A61M2025/0046 , A61M2025/09066 , A61M2025/09083 , A61M2025/091 , A61M2025/09133
摘要： A steerable guidewire having a sharpened re-entry tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the re-entry tip.
摘要翻译：一种可转向导丝，其具有锐化的再进入尖端，其包括纵向海波管和附接到海波管的远端的互锁弹簧线圈，并且还包括连接到弹簧线圈的远端的可纵向移动的偏转构件，保持构件，其从海波波的远端延伸到弹簧线圈的远端，以提供重入口尖端的非常精确的偏转。

2. 发明申请

US20060241519A1 Guidewire with deflectable tip 审中-公开
公开(公告)号：US20060241519A1
公开(公告)日：2006-10-26
申请号：US11473764
申请日：2006-06-23
申请人： Hikmat Hojeibane , David Grewe
发明人： Hikmat Hojeibane , David Grewe
IPC分类号： A61M25/00
CPC分类号： A61M25/0147 , A61M25/0138 , A61M25/0152 , A61M25/09 , A61M25/09033 , A61M2025/0042 , A61M2025/09083 , A61M2025/09133
摘要： A bi-directional steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and a spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip.

3. 发明申请

US20070219465A1 Guidewire with deflectable tip having improved flexibility 有权
标题翻译：具有可偏转尖端的导丝具有改善的柔性
公开(公告)号：US20070219465A1
公开(公告)日：2007-09-20
申请号：US11590625
申请日：2006-10-31
申请人： Rudolph Cedro , David Grewe , Hikmat Hojeibane
发明人： Rudolph Cedro , David Grewe , Hikmat Hojeibane
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61M25/0045 , A61M25/01 , A61M25/0138 , A61M25/0147 , A61M25/0152 , A61M25/09033 , A61M2025/0042 , A61M2025/0046 , A61M2025/09066 , A61M2025/09083 , A61M2025/091 , A61M2025/09133
摘要： A steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining ribbon which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip. The distal end of the deflection member has “skived,” or tapered, sides to enhance the flexibility of the guidewire.
摘要翻译：一种可导向的导丝，其具有可偏转的远端，其包括纵向海波管和附接到海波管的远端的互锁弹簧线圈，并且还包括可纵向移动的偏转构件，其连接到弹簧线圈的远端，并且尖端保持带其从海波管的远端延伸到弹簧线圈的远端，以提供远端尖端的非常精确的偏转。偏转构件的远端具有“滑动”或锥形侧面以增强导丝的柔性。

4. 发明申请

US20070213689A1 Deflectable tip infusion guidewire 审中-公开
标题翻译：可偏转尖端输液导丝
公开(公告)号：US20070213689A1
公开(公告)日：2007-09-13
申请号：US11590536
申请日：2006-10-31
申请人： David Grewe , Hikmat Hojeibane
发明人： David Grewe , Hikmat Hojeibane
IPC分类号： A61M25/08
CPC分类号： A61M25/09 , A61M25/0045 , A61M25/0138 , A61M25/0147 , A61M25/0152 , A61M25/09033 , A61M2025/0042 , A61M2025/0046 , A61M2025/09083 , A61M2025/091 , A61M2025/09133
摘要： A steerable infusion guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil which carry an infusion tube which is attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip of the guidewire.
摘要翻译：一种具有可偏转的远端的可引导输注导线，其包括纵向海波管和携带输注管的互锁弹簧线圈，所述输液管附接到所述海波管的远端，并且还包括可纵向移动的偏转构件，所述弹簧线圈和从所述海波管的远端延伸到所述弹簧线圈的远端的尖端保持构件，用于提供所述导丝的远侧末端的非常精确的偏转。

5. 发明授权

US07128718B2 Guidewire with deflectable tip 有权
公开(公告)号：US07128718B2
公开(公告)日：2006-10-31
申请号：US10224168
申请日：2002-08-20
申请人： Hikmat Hojeibane , David Grewe
发明人： Hikmat Hojeibane , David Grewe
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/0147 , A61M25/0138 , A61M25/0152 , A61M25/09 , A61M25/09033 , A61M2025/0042 , A61M2025/09083 , A61M2025/09133
摘要： A bi-directional steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and a spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip.

6. 发明申请

US20120130412A1 TOTAL OCCLUSION GUIDEWIRE DEVICE 有权
标题翻译：总体指导设备
公开(公告)号：US20120130412A1
公开(公告)日：2012-05-24
申请号：US13297719
申请日：2011-11-16
申请人： Thomas W. Duerig , Hikmat Hojeibane , David C. Majercak
发明人： Thomas W. Duerig , Hikmat Hojeibane , David C. Majercak
IPC分类号： A61B17/22
CPC分类号： A61B17/22 , A61B17/3207 , A61B17/320758 , A61B2017/22042 , A61B2017/22044 , A61B2017/22068 , A61B2017/22069 , A61B2017/320004 , A61M25/09 , A61M25/0905 , A61M2025/09183
摘要： A guidewire comprising a spreader or at least one centering device which may be used to open occluded vessels or other biological passages, especially chronic total occlusions. The guidewire may be used to either open the lumen or to center a boring device within the lumen, so that the chronic total occlusion can be crossed, and an interventional procedure can then be performed.
摘要翻译：一种导丝，其包括可以用于打开闭塞血管或其他生物通道的扩张器或至少一个定中心装置，特别是慢性完全闭塞。导丝可以用于打开内腔或使镗孔装置居中在管腔内，使得慢性全部闭塞可以交叉，然后可以执行介入手术。

7. 发明授权

US07867176B2 Variable stiffness guidewire 有权
标题翻译：可变刚度导丝
公开(公告)号：US07867176B2
公开(公告)日：2011-01-11
申请号：US11318825
申请日：2005-12-27
申请人： Mina Wu , Hikmat Hojeibane
发明人： Mina Wu , Hikmat Hojeibane
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/09158 , A61M2025/09175
摘要： A guidewire navigable through body vessels of a human subject for delivery of a catheter or the like is provided. The guidewire has a tube which receives a corewire that protrudes beyond a distal portion of the tube. The protruding portion of the corewire is surrounded by a spring and shapeable into a curve or arc. The cross-sectional shape of the spring may be varied in order to promote bending flexibility and curvature or to favor curvature of a chosen type. The corewire is axially movable with respect to the tube, which compresses or stretches the spring to change the stiffness of the spring. The tube has a proximal portion comprised of a relatively rigid material, such as stainless steel, while a distal portion is comprised of a more flexible material, such as a nitinol.
摘要翻译：提供了可以通过人体受试者的身体血管导航以便传送导管等的导丝。引导线具有一个管，该管接收突出超过管的远端部分的芯线。芯线的突出部分被弹簧包围，并可成形成曲线或弧形。可以改变弹簧的横截面形状，以便促进弯曲柔性和曲率，或者有助于所选类型的曲率。芯线可相对于管轴向移动，该管压缩或拉伸弹簧以改变弹簧的刚度。管具有由相对刚性的材料（例如不锈钢）组成的近端部分，而远侧部分由更柔性的材料（例如镍钛诺）组成。

8. 发明申请

US20080058764A1 Catheter Tip Configuration for Improved Crossability and Trackability 审中-公开
标题翻译：导管尖端配置提高了可交叉性和可追溯性
公开(公告)号：US20080058764A1
公开(公告)日：2008-03-06
申请号：US11468200
申请日：2006-08-29
申请人： David C. Majercak , Hikmat Hojeibane
发明人： David C. Majercak , Hikmat Hojeibane
IPC分类号： A61M25/00
CPC分类号： A61M25/0041 , A61M25/0068 , A61M25/008 , A61M25/01 , A61M25/10
摘要： Balloon catheter designs are disclosed where the as-molded distal tip portion assumes a generally non-linear configuration. The non-linear tip configuration minimizes the gap between the wall of the catheter and the guidewire when the catheter passes over the guidewire when threaded through tortuous portions of the vasculature. The edge of the tip portion may be bias-cut angled with respect to the axis of the catheter to further reduce the gap. The disclosure also describes methods to use the catheter designs.
摘要翻译：公开了气囊导管设计，其中模制的远端尖端部分呈现大致非线性构型。当螺纹穿过脉管系统的曲折部分时，当导管通过导丝时，非线性尖端构造使导管的壁和导丝之间的间隙最小化。尖端部分的边缘可以相对于导管的轴线偏置成角度以进一步减小间隙。本公开还描述了使用导管设计的方法。

9. 发明授权

US07070616B2 Implantable valvular prosthesis 有权
标题翻译：可植入瓣膜假体
公开(公告)号：US07070616B2
公开(公告)日：2006-07-04
申请号：US10699014
申请日：2003-10-31
申请人： David Christopher Majercak , Hikmat Hojeibane
发明人： David Christopher Majercak , Hikmat Hojeibane
IPC分类号： A61F2/06
CPC分类号： A61F2/2475 , A61F2/2418 , A61F2220/0016 , A61F2230/0054
摘要： The present invention relates to a medical device, and in particular, to a stent-based valve. The valve includes a radially expandable structural frame including an anchor structure having a first and a second open end, a connecting member having a first and a second end, and a cantilever valve strut having a first and a second end. The first end of the connecting member is attached to the second end of the anchor structure. The first end of the cantilever valve strut is cooperatively associated with the second end of the connecting member. The prosthetic valve further includes a biocompatible membrane assembly having a substantially tubular configuration disposed longitudinally about at least a portion of the connecting member. The membrane assembly has a first end having a first diameter and a second end having a second diameter, wherein the first diameter is greater than the second diameter. The first end of the membrane assembly is attached along the second end of the cantilever valve strut.
摘要翻译：本发明涉及一种医疗装置，特别涉及一种基于支架的阀。该阀包括具有第一和第二开口端的锚定结构的可径向扩张的结构框架，具有第一和第二端的连接构件以及具有第一和第二端的悬臂阀支柱。连接构件的第一端附接到锚结构的第二端。悬臂阀支柱的第一端与连接构件的第二端协作关联。假体瓣膜还包括生物相容性膜组件，其具有围绕连接构件的至少一部分纵向设置的大致管状结构。膜组件具有第一端和第二端，第一端具有第一直径，第二端具有第二直径，其中第一直径大于第二直径。膜组件的第一端沿悬臂阀支柱的第二端连接。

10. 发明授权

US06565600B2 Articulated expandable intraluminal stent 有权
标题翻译：铰接式扩张型管腔内支架
公开(公告)号：US06565600B2
公开(公告)日：2003-05-20
申请号：US09778148
申请日：2001-02-07
申请人： Hikmat Hojeibane
发明人： Hikmat Hojeibane
IPC分类号： A61M2900
CPC分类号： A61F2/91 , A61F2/07 , A61F2/89 , A61F2/915 , A61F2/958 , A61F2002/30143 , A61F2002/30153 , A61F2002/30154 , A61F2002/30156 , A61F2002/825 , A61F2002/828 , A61F2002/91525 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2220/005 , A61F2220/0058 , A61F2230/0013 , A61F2230/0017 , A61F2230/0019 , A61F2230/0021 , A61F2230/0023
摘要： The present invention includes: an expandable, tubular shaped prosthesis having first and second ends and a wall surface disposed between the first and second ends, the wall surface being formed by a plurality of intersecting elongate members; and a catheter, having an expandable, inflatable portion associated therewith and including means for mounting and retaining the expandable tubular shaped prosthesis on the expandable, inflatable portion, whereby upon inflation of the expandable, inflatable portion of the catheter, the prosthesis is formed radially outwardly into contact with the body passageway. The articulation in the form of a rounded wire frame loop connects similar stent bodies. Also, rounded open connectors and shortened cells in the stent allow for greater flexibility.
摘要翻译：本发明包括：具有第一和第二端以及设置在第一和第二端之间的壁表面的可膨胀的管状假体，所述壁表面由多个相交的细长构件形成; 以及导管，其具有与之相关联的可膨胀的可充气部分，并且包括用于将可膨胀管状假体安装并保持在可膨胀的可充气部分上的装置，由此在导管的可膨胀的可充气部分膨胀时，假体径向向外形成与身体通道接触。圆形线框环形式的铰接连接相似的支架体。此外，支架中的圆形开放连接器和缩短的细胞允许更大的灵活性。

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