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1. 发明授权

US08530417B2 Y-shaped polyethylene glycol modified G-CSF, the preparation and use thereof 有权
标题翻译： Y型聚乙二醇改性G-CSF，的制备及应用
公开(公告)号：US08530417B2
公开(公告)日：2013-09-10
申请号：US12811103
申请日：2007-12-29
申请人： Shiyuan Wang , Jianhua Zheng , Li Sun , Huili Cai , Meihua Yang , Yan He , Ping Chen , Hongyuan Deng , Liping Zhong , Shuying Huang
发明人： Shiyuan Wang , Jianhua Zheng , Li Sun , Huili Cai , Meihua Yang , Yan He , Ping Chen , Hongyuan Deng , Liping Zhong , Shuying Huang
IPC分类号： A61K38/00 , A61K38/16 , A61K38/17 , A61K38/24 , C07K1/00 , C07K16/00
CPC分类号： C07K1/1077 , A61K47/60 , C07K14/535
摘要： The present invention relates to granulocyte colony stimulating factor (G-CSF) modified with Y-shaped branched polyethylene glycol (YPEG-G-CSF) at a specific lysine (Lys 17) and the preparation thereof, as well as the pharmaceutical composition comprising YPEG-G-CSF and use thereof.
摘要翻译：本发明涉及用特定赖氨酸（Lys 17）Y型支链聚乙二醇（YPEG-G-CSF）修饰的粒细胞集落刺激因子（G-CSF）及其制备方法，以及包含YPEG的药物组合物 -G-CSF及其用途。

2. 发明申请

US20110280826A1 Y-SHAPED POLYETHYLENE GLYCOL MODIFIED G-CSF, THE PREPARATION AND USE THEREOF 有权
标题翻译： Y型聚乙烯甘油改性G-CSF，的制备及其用途
公开(公告)号：US20110280826A1
公开(公告)日：2011-11-17
申请号：US12811103
申请日：2007-12-29
申请人： Shiyuan Wang , Jianhua Zheng , Li Sun , Huili Cai , Meihua Yang , Yan He , Ping Chen , Hongyuan Deng , Liping Zhong , Shuying Huang
发明人： Shiyuan Wang , Jianhua Zheng , Li Sun , Huili Cai , Meihua Yang , Yan He , Ping Chen , Hongyuan Deng , Liping Zhong , Shuying Huang
IPC分类号： A61K38/19 , C07K14/535 , A61P37/06 , A61P35/00 , A61P7/00 , A61P35/02
CPC分类号： C07K1/1077 , A61K47/60 , C07K14/535
摘要： The present invention relates to granulocyte colony stimulating factor (G-CSF) modified with Y-shaped branched polyethylene glycol (YPEG-G-CSF) at a specific lysine (Lys 17) and the preparation thereof, as well as the pharmaceutical composition comprising YPEG-G-CSF and use thereof.
摘要翻译：本发明涉及用特定赖氨酸（Lys 17）Y型支链聚乙二醇（YPEG-G-CSF）修饰的粒细胞集落刺激因子（G-CSF）及其制备方法，以及包含YPEG的药物组合物 -G-CSF及其用途。

3. 发明申请

US20120187089A1 HIGH-VOLTAGE, SUPER-VOLTAGE AND HEAVY CURRENT BREAKER 审中-公开
标题翻译：高电压，超电流和重电流断路器
公开(公告)号：US20120187089A1
公开(公告)日：2012-07-26
申请号：US13393225
申请日：2009-10-27
申请人： Xuanshu Chen , Yuan Pan , Fei Liu , Junjia He , Zhao Yuan , Ting Yin , Yan Du , Yan He
发明人： Xuanshu Chen , Yuan Pan , Fei Liu , Junjia He , Zhao Yuan , Ting Yin , Yan Du , Yan He
IPC分类号： H01H33/14
CPC分类号： H01H33/14 , H01H9/167 , H01H9/563 , H01H33/16 , H01H33/59 , H01H33/6662 , H01H2009/543
摘要： A high-voltage, super-voltage and heavy current breaker is formed by combining intelligent optical vacuum breaker modules (21) with phase selection function in series and/or parallel connection. Each vacuum breaker module (21) is connected each other in series after being connected in parallel with a resistance capacitance device or with a resistance capacitance device and a zinc oxide arrester valve plate (22). Tight coupling reactors are connected with several serial branches of the vacuum breaker module (21) simultaneously to achieve parallel connection of several serial branches of the vacuum breaker module (21). The breaker distributes the high-voltage and heavy current into the low voltage and low current serial and parallel vacuum breaker modules (21) to share.
摘要翻译：通过将智能光学真空断路器模块（21）与串联和/或并联的相位选择功能相结合，形成高压，超电压和大电流断路器。每个真空断路器模块（21）在与电阻电容器件或电阻电容器件和氧化锌避雷器阀板（22）并联连接之后彼此串联连接。紧耦合电抗器同时与真空断路器模块（21）的几个串联连接，以实现真空断路器模块（21）的几个串联分支的并联连接。断路器将高压和大电流分配到低压和低电流串联和并联真空断路器模块（21）中以共享。

4. 发明授权

US06969452B2 Two-dimensional protein separations using chromatofocusing and multiplexed capillary gel electrophoresis 有权
标题翻译：使用色谱聚焦和多重毛细管凝胶电泳的二维蛋白质分离
公开(公告)号：US06969452B2
公开(公告)日：2005-11-29
申请号：US10377909
申请日：2003-02-28
申请人： Yan He , Ho-Ming Pang , Siquan Luo , Futian Han
发明人： Yan He , Ho-Ming Pang , Siquan Luo , Futian Han
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44773
摘要： Disclosed is a two-dimensional protein separation method. It makes separating a protein sample by chromatofocusing into a plurality of aliquots, and then loading each aliquot into a separate capillary tube; and separating each aliquot by multiplexed capillary electrophoresis to produce a two-dimensional array of separated proteins. A preferred integrated buffer for this system is also disclosed.
摘要翻译：公开了二维蛋白质分离方法。它使蛋白质样品通过色谱聚焦分成多个等分试样，然后将每个等分试样装载到单独的毛细管中; 并通过多重毛细管电泳分离每个等分试样以产生分离的蛋白质的二维阵列。还公开了该系统的优选集成缓冲器。

5. 发明申请

US20120036459A1 Apparatuses and Methods for Arranging and Manipulating Menu Items 审中-公开
标题翻译：用于排列和操作菜单项的设备和方法
公开(公告)号：US20120036459A1
公开(公告)日：2012-02-09
申请号：US13052786
申请日：2011-03-21
申请人： Cheng-Yu Pei , Yan He
发明人： Cheng-Yu Pei , Yan He
IPC分类号： G06F3/048
CPC分类号： G06F3/04883 , G06F3/04815 , G06F3/0482
摘要： An electronic interaction apparatus is provided with a processing unit. The processing unit configures a touch screen to display a first set of the menu items in a first row on the touch screen, and to display a second set of the menu items in a second row on the touch screen. Particularly, the first row is lower than the second row, and the menu items in the second set are smaller than the menu items in the first set.
摘要翻译：电子交互装置具有处理单元。处理单元配置触摸屏以在触摸屏上的第一行中显示菜单项的第一组，并且在触摸屏上的第二行中显示第二组菜单项。特别地，第一行低于第二行，并且第二组中的菜单项小于第一组中的菜单项。

6. 发明申请

US20110156683A1 Current mode buck-boost DC-DC controller 有权
标题翻译：电流模式降压 - 升压DC-DC控制器
公开(公告)号：US20110156683A1
公开(公告)日：2011-06-30
申请号：US12925130
申请日：2010-10-14
申请人： Hai Bo Zhang , Yan He
发明人： Hai Bo Zhang , Yan He
IPC分类号： G05F1/10
CPC分类号： H02M3/1582
摘要： A current mode DC-DC controller operates with high efficiency even when the input and output voltages are close. Switches selectively connecting an input, ground and an output to inductor terminals are controlled in a buck/boost region to alternate between operation as a buck converter and operation as a boost converter. The number of switches repeatedly changing state is thus reduced, lowering switching losses and improving conversion efficiency. Current through the inductor during operation is sensed and compared to an error value to control switching from buck mode operation to boost mode operation and back.
摘要翻译：即使输入和输出电压接近，电流模式DC-DC控制器也能以高效率运行。选择性地将输入，接地和输出连接到电感器端子的开关在降压/升压区域中被控制，以在作为降压转换器的操作和作为升压转换器的操作之间交替。因此，重复改变状态的开关数量减少，降低开关损耗并提高转换效率。在运行期间通过电感器的电流被感测并与误差值进行比较，以控制从降压模式操作到升压模式操作和返回的切换。

7. 发明授权

US09071140B2 Current mode buck-boost DC-DC controller 有权
标题翻译：电流模式降压 - 升压DC-DC控制器
公开(公告)号：US09071140B2
公开(公告)日：2015-06-30
申请号：US12925130
申请日：2010-10-14
申请人： Hai Bo Zhang , Yan He
发明人： Hai Bo Zhang , Yan He
IPC分类号： G05F1/00 , H02M3/158
CPC分类号： H02M3/1582
摘要： A current mode DC-DC controller operates with high efficiency even when the input and output voltages are close. Switches selectively connecting an input, ground and an output to inductor terminals are controlled in a buck/boost region to alternate between operation as a buck converter and operation as a boost converter. The number of switches repeatedly changing state is thus reduced, lowering switching losses and improving conversion efficiency. Current through the inductor during operation is sensed and compared to an error value to control switching from buck mode operation to boost mode operation and back.
摘要翻译：即使输入和输出电压接近，电流模式DC-DC控制器也能以高效率运行。选择性地将输入，接地和输出连接到电感器端子的开关在降压/升压区域中被控制，以在作为降压转换器的操作和作为升压转换器的操作之间交替。因此，重复改变状态的开关数量减少，降低开关损耗并提高转换效率。在运行期间通过电感器的电流被感测并与误差值进行比较，以控制从降压模式操作到升压模式操作和返回的切换。

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