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1. 发明授权

US11186810B2 Cell culture vessel 有权
公开(公告)号：US11186810B2
公开(公告)日：2021-11-30
申请号：US16084283
申请日：2016-03-16
申请人： Shimadzu Corporation , Yokohama City University , Osaka University , CORNING INCORPORATED
发明人： Tomoki Ohkubo , Masaki Kanai , Hirohisa Abe , Hideki Taniguchi , Masahiro Kinooka , Goro Kobayashi , Takanori Takebe
IPC分类号： C12M1/00 , C12M3/00 , C12M3/06 , C12M1/34
摘要： A cell culture container includes a storage container, a cell culture area, a culture solution supply unit, and a discharge unit. The cell culture area is a region for culturing cells, and is provided in the storage container. The culture solution supply unit supplies the culture solution into the cell culture area at a flow rate equal to or less than a predetermined flow rate. The discharge unit discharges the liquid in the cell culture area to the outside of the storage container. A rectification unit is a structure in which a plurality of outflow ports are uniformly arranged in a direction perpendicular to the flow direction of the culture solution from the culture solution supply unit to the discharge unit.

2. 发明授权

US10684279B2 Device for operating magnetic particles 有权
公开(公告)号：US10684279B2
公开(公告)日：2020-06-16
申请号：US15891509
申请日：2018-02-08
申请人： SHIMADZU CORPORATION
发明人： Masaki Kanai , Hiroyuki Jikuya , Tetsuo Ohashi , Seiya Fujiwara
IPC分类号： G01N33/543 , G01N1/34 , B03C1/00 , G01N1/40
摘要： To provide a device for operating magnetic particles capable of treating large quantity, and retaining a gel-like medium layer stably, a vessel is formed so that an area perpendicular to a longitudinal direction in a large-diameter part packed with a liquid layer is larger than an area perpendicular to the longitudinal direction in the small-diameter part packed with a gel-like medium layer. Therefore, in the vessel, it is possible to reduce the diameter of the small-diameter part while keeping the capacity of the large-diameter part large. As a result, in the vessel, it is possible to treat large quantity in the liquid layer, and it is possible to retain the gel-like medium layer stably.

3. 发明申请

US20140290491A1 COLUMN UNIT AND GAS CHROMATOGRAPHY DEVICE PROVIDED WITH THE SAME 有权
标题翻译：色谱柱和气相色谱装置
公开(公告)号：US20140290491A1
公开(公告)日：2014-10-02
申请号：US14226018
申请日：2014-03-26
申请人： SHIMADZU CORPORATION
发明人： Masaki Kanai , Takahiro Nishimoto , Masanori Nishino , Satoshi Matsuoka
IPC分类号： G01N30/30
CPC分类号： G01N30/30 , G01N30/6052 , G01N30/6095 , G01N2030/025 , G01N2030/3007 , G01N2030/303 , G01N2030/3061 , G01N2030/3084
摘要： A housing of a column unit is tubular-shaped, and includes a first opening and a second opening, and an inner space separated from outside air by an insulating material. An air cooling section including a cooling device is arranged on a side of the first opening of the housing. At the time of cooling the inside of the inner space of the housing, air is caused, by a fan, to flow through the air cooling section and from the side of the first opening to a side of the second opening. A column section including a separation column and a heater is arranged inside the housing. A gap through which air flows from the first opening to the second opening is formed between the column section and an inner wall of the inner space of the housing.
摘要翻译：柱单元的壳体是管状的，并且包括第一开口和第二开口，以及通过绝缘材料与外部空气隔开的内部空间。包括冷却装置的空气冷却部分布置在壳体的第一开口的一侧。在冷却壳体的内部空间的内部，通过风扇使空气流过空气冷却部分并从第一开口的一侧流到第二开口的一侧。包括分离柱和加热器的柱部分布置在壳体内。在柱部和壳体的内部空间的内壁之间形成有从第一开口到第二开口的空气流过的间隙。

4. 发明授权

US10941394B2 Device for manipulating magnetic particles and method for manipulating magnetic particles 有权
公开(公告)号：US10941394B2
公开(公告)日：2021-03-09
申请号：US15543425
申请日：2015-01-15
申请人： SHIMADZU CORPORATION
发明人： Masaki Kanai , Tetsuo Ohashi , Takahiro Nishimoto
IPC分类号： B01L3/00 , C12N15/10 , B03C1/30 , B03C1/01 , B03C1/033 , B03C1/28 , C07K1/14 , C07K16/00
摘要： A device for manipulating magnetic particles includes a gelled medium layer and liquid layers alternately stacked in a tubular container along a longitudinal direction of the container. A magnetic particle movement portion for moving magnetic particles exists along an inner wall surface of the container, and the magnetic particle movement portion extends along the longitudinal direction of the container. At a portion where the gelled medium layer is loaded, the cross-sectional shape of the container inner wall in a plane perpendicular to the longitudinal direction of the container is non-circular, and the shape of the magnetic particle movement portion in the cross section is a curved shape or an angular shape.

5. 发明申请

US20150268201A1 GAS CHROMATOGRAPH DEVICE 审中-公开
标题翻译：气体色谱装置
公开(公告)号：US20150268201A1
公开(公告)日：2015-09-24
申请号：US14437863
申请日：2012-10-25
申请人： SHIMADZU CORPORATION
发明人： Masaki Kanai , Satoshi Matsuoka , Masanori Nishino , Takahiro Nishimoto
IPC分类号： G01N30/30 , G01N30/16
CPC分类号： G01N30/30 , G01N30/16 , G01N30/54 , G01N30/60 , G01N2030/3084
摘要： A gas chromatograph includes a column module for independently adjusting the temperature of a separation column. The column module is held by an oven with the separation column being horizontal. The column module includes the separation column for separating a sample gas into components, a column accommodating member accommodating inside the separation column while surrounding the separation column by a heat insulating member, and including a gap between the separation column and the heat insulating member for air to flow along the separation column, and a heater, provided inside the column accommodating member, for heating the separation column by being in direct or indirect contact with the separation column. The column accommodating member includes an air inlet port for introducing external air into the gap between the separation column and the heat insulating member, and an air outlet port for exhausting air in the gap.
摘要翻译：气相色谱仪包括用于独立调节分离塔的温度的色谱柱模块。柱模块由烘箱保持，分离柱是水平的。柱模块包括用于将样品气体分离成组分的分离塔，容纳在分离塔内部的塔容纳构件，同时通过绝热构件围绕分离塔，并且在分离塔和用于空气的隔热构件之间包括间隙沿着分离柱流动，以及设置在塔容纳构件内部的加热器，用于通过与分离塔直接或间接接触来加热分离塔。塔容纳构件包括用于将外部空气引入分离柱和绝热构件之间的间隙的空气入口端口和用于排出间隙中的空气的空气出口。

6. 发明授权

US11142735B2 Cell treatment container and cell treatment device 有权
公开(公告)号：US11142735B2
公开(公告)日：2021-10-12
申请号：US16712238
申请日：2019-12-12
申请人： Shimadzu Corporation
发明人： Chikara Miyake , Masaki Kanai , Yoichi Fujiyama , Satoshi Kuramoto
IPC分类号： C12M3/06 , C12M1/00 , B01L3/00
摘要： To provide a cell treatment container, including: a first member having a flow path in which a cell suspension including a liquid and cells dispersed in the liquid flows through, the flow path formed on a surface of the first member; a second member arranged to face the surface of the first member; and a damming formed in one or both of the first member and the second member, in which the damming is provided with a protrusion part protruding from the first member into the flow path to form a gap for allowing the liquid in the cell suspension to pass through the gap and for damming up the cells in the cell suspension, and a pillar extending from the protrusion part at a first end and being joined to the second member at a second end.

7. 发明申请

US20190136171A1 CELL CULTURE CONTAINER AND CELL CULTURE METHOD USING THE CONTAINER 审中-公开
公开(公告)号：US20190136171A1
公开(公告)日：2019-05-09
申请号：US16235432
申请日：2018-12-28
申请人： SHIMADZU CORPORATION , KYOTO UNIVERSITY , WASEDA UNIVERSITY
发明人： Tatsuya Munaka , Hirohisa Abe , Masaki Kanai , Masakazu Akechi , Taira Maekawa , Shinya Kimura , Eishi Ashihara , Shuichi Shoji , Kentaro Kawai
IPC分类号： C12M1/04 , C12M1/12 , C12M1/00 , C12N5/074 , C12M1/32
摘要： A well has a pair of side surfaces, and one of the side surfaces is in contact with a compartment of a first channel with a gas-permeable membrane being interposed therebetween and the other side surface is in contact with a compartment of a second channel with a gas-permeable membrane being interposed therebetween. The well is filled with a liquid cell culture medium, and in such a state, a high-concentration gas and a low-concentration gas, which are different in the concentration of a specific component from each other, are allowed to flow through the first and second channels, respectively, to form a concentration distribution of the specific component in the well.

8. 发明授权

US10029253B2 Micro droplet operation device and reaction processing method using the same 有权
公开(公告)号：US10029253B2
公开(公告)日：2018-07-24
申请号：US14052299
申请日：2013-10-11
申请人： SHIMADZU CORPORATION
发明人： Masakazu Akechi , Masaki Kanai , Takahiro Nishimoto , Nobuhiro Hanafusa
IPC分类号： B01L3/00 , C12M1/32 , G01N35/00 , G01N35/10
摘要： Micro droplets are accurately placed in a reaction well. The reaction well (5) is formed in one surface of a well base (3). A channel base (11) is placed on the well base (3). The channel base (11) has, in its surface joined to the well base (3), a liquid introduction channel (12a) and a reaction well air vent channel (18a). The channel base (11) also has a recess (27) formed opposite to the reaction well (5) and recessed upward from the upper surface of the liquid introduction channel (12a). When viewed from above, a shoulder part (26) of the recess (27) is placed near the connection part between the reaction well (5) and the liquid introduction channel (12a) and is closer to the center of the reaction well (5) than a shoulder part (16) of the reaction well (5).

9. 发明申请

US20170120259A1 DEVICE FOR CONSTANT-VOLUME COLLECTION USING CENTRIFUGATION OR FOR FURTHER STORAGE 审中-公开
公开(公告)号：US20170120259A1
公开(公告)日：2017-05-04
申请号：US15319960
申请日：2015-05-25
申请人： SHIMADZU CORPORATION
发明人： Ippei Takeuchi , Masakazu Akechi , Masaki Kanai , Shinobu Kudoh
IPC分类号： B04B5/02 , G01N1/40 , B04B11/04
CPC分类号： B04B5/02 , B01L3/50273 , B01L2200/026 , B01L2200/04 , B01L2300/0803 , B01L2300/0864 , B01L2400/0406 , B01L2400/0409 , B01L2400/0683 , B04B5/0407 , B04B11/04 , G01N1/4077 , G01N21/07 , G01N33/491 , G01N2001/4083 , G01N2035/00504 , G01N2035/0441
摘要： A centrifugal separation device including a supporter attached to a centrifuge and a divisional part removable from the supporter is provided. The divisional part has two flow channels and an extracting part. The flow channels extend substantially in parallel to the direction in which centrifugal force acts, and are connected to each other on the leading end side in the direction in which centrifugal force acts. One of the flow channels is a sample flow channel having a sample inlet on the base end side in the direction in which centrifugal force acts, and the other flow channel is an air-discharging flow channel having an outlet on the base end side. The extracting part includes part of the sample flow channel, and has a connecting part for the part to be cut off from the remainder of the sample flow channel.

10. 发明授权

US09594064B2 Plate-type column, temperature regulation system and gas chromatograph system 有权
标题翻译：板式柱，温度调节系统和气相色谱系统
公开(公告)号：US09594064B2
公开(公告)日：2017-03-14
申请号：US13896138
申请日：2013-05-16
申请人： SHIMADZU CORPORATION
发明人： Masaki Kanai , Takahiro Nishimoto , Masanori Nishino , Satoshi Matsuoka
IPC分类号： G01N30/90 , G01N30/30 , G01N30/54 , G01N30/60
CPC分类号： G01N30/90 , G01N30/30 , G01N30/54 , G01N30/6004 , G01N2030/3007
摘要： Provided is a plate-type column which allows the temperature of its inner passage to be rapidly increased or decreased while ensuring the correctness of an analysis or other operations. A plate-type column 10 includes: a plate-shaped main body 11; projecting portions 12 and 13 protruding from a circumferential edge of the main body 11; and a fluid-flow passage 14 extending in the main body 11 and the projecting portions 12 and 13. An intermediate portion of the passage 14 is provided in the main body 11, while each of the end portions of the passage 14 extends from the main body 11 through the projecting portion 12 or 13, with each of the end portions being open to the outside at the tip of the projecting portion 12 or 13.
摘要翻译：提供一种板型柱，其允许其内通道的温度快速增加或减少，同时确保分析或其他操作的正确性。板状柱10包括：板状主体11; 从主体11的周缘突出的突出部12,13; 以及在主体11和突出部分12和13中延伸的流体流动通道14.通道14的中间部分设置在主体11中，而通道14的每个端部从主体主体11穿过突出部分12或13，其中每个端部在突出部分12或13的尖端处向外开口。

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