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1. 发明申请

US20210214868A1 BRAIDING MECHANISM AND METHODS OF USE 有权
公开(公告)号：US20210214868A1
公开(公告)日：2021-07-15
申请号：US17130224
申请日：2020-12-22
申请人： SEQUENT MEDICAL, INC.
发明人： James M. Thompson , Brian J. Cox , Robert Rosenbluth , Philippe Marchand , John Nolting , Darrin J. Kent , Tan Q. Dinh , Hung P. Tran , James A. Millburn
IPC分类号： D04C3/40 , D04C3/42 , D04C1/12 , D04C3/48
摘要： Methods of braiding using a braiding mechanism are described. The braiding mechanism includes an array of filament engagement elements, a mandrel extending from the center of the circular array, a plurality of actuators disposed operably about the array, and a rotating mechanism adapted to rotate one or more filaments. The plurality of filaments are loaded onto the mandrel by looping a middle portion of each filament of the plurality of filaments over an end of the mandrel and extend radially toward and contact the circumferential edge of the circular array of filament engagement elements. The plurality of actuators are operated to engage a first subset of the plurality of filaments and move the engaged filaments in a generally radial direction to a position beyond the circumferential edge of the array. The rotating mechanism is operated to move the engaged filaments about the mandrel axis.

2. 发明申请

US20140330299A1 EMBOLIC OCCLUSION DEVICE AND METHOD 审中-公开
标题翻译： EMBOLIC OCCLUSION设备和方法
公开(公告)号：US20140330299A1
公开(公告)日：2014-11-06
申请号：US14271099
申请日：2014-05-06
申请人： Sequent Medical, Inc.
发明人： Robert Rosenbluth , Brian J. Cox , William R. Patterson
IPC分类号： A61B17/12
CPC分类号： A61B17/1214 , A61B17/12113 , A61B17/1215 , A61B17/12154 , A61B17/12163 , A61B17/12168 , A61B2017/00526
摘要： An occlusion device including a tubular braided member having a first end and a second end and extending along a longitudinal axis, the tubular braided member having a repeating pattern of larger diameter portions and smaller diameter portions arrayed along the longitudinal axis, and at least one metallic coil member extending coaxially along at least a portion of the braided member, the at least one metallic coil member having an outer diameter and an inner diameter, wherein the smaller diameter portions of the tubular braided member have an outer diameter and an inner diameter, and wherein at least one of the outer diameter and inner diameter of the tubular braided member is configured to closely match a directly opposing diameter of the metallic coil member.
摘要翻译：一种闭塞装置，包括具有第一端和第二端并沿着纵向轴线延伸的管状编织构件，所述管状编织构件具有沿着纵向轴线排列的较大直径部分和较小直径部分的重复图案，以及至少一个金属所述线圈构件沿着所述编织构件的至少一部分同轴地延伸，所述至少一个金属线圈构件具有外径和内径，其中所述管状编织构件的较小直径部分具有外径和内径，以及其中所述管状编织构件的外径和内径中的至少一个被配置为紧密地匹配所述金属线圈构件的直接相对的直径。

3. 发明授权

US11352724B2 Braiding mechanism and methods of use 有权
公开(公告)号：US11352724B2
公开(公告)日：2022-06-07
申请号：US17130224
申请日：2020-12-22
申请人： SEQUENT MEDICAL, INC.
发明人： James M. Thompson , Brian J. Cox , Robert Rosenbluth , Philippe Marchand , John Nolting , Darrin J. Kent , Tan Q. Dinh , Hung P. Tran , James A. Millburn
IPC分类号： D04C3/40 , D04C3/42 , D04C1/12 , D04C3/48
摘要： Methods of braiding using a braiding mechanism are described. The braiding mechanism includes an array of filament engagement elements, a mandrel extending from the center of the circular array, a plurality of actuators disposed operably about the array, and a rotating mechanism adapted to rotate one or more filaments. The plurality of filaments are loaded onto the mandrel by looping a middle portion of each filament of the plurality of filaments over an end of the mandrel and extend radially toward and contact the circumferential edge of the circular array of filament engagement elements. The plurality of actuators are operated to engage a first subset of the plurality of filaments and move the engaged filaments in a generally radial direction to a position beyond the circumferential edge of the array. The rotating mechanism is operated to move the engaged filaments about the mandrel axis.

4. 发明申请

US20160015396A1 METHODS AND DEVICES FOR TREATMENT OF VASCULAR DEFECTS 审中-公开
标题翻译：用于治疗血管缺损的方法和装置
公开(公告)号：US20160015396A1
公开(公告)日：2016-01-21
申请号：US14869688
申请日：2015-09-29
申请人： SEQUENT MEDICAL, INC.
发明人： Brian J. Cox , Dean Schaefer , Robert F. Rosenbluth
IPC分类号： A61B17/12 , A61F2/91 , A61F2/915 , A61F2/90
CPC分类号： A61B17/12031 , A61B17/12022 , A61B17/12118 , A61B17/12172 , A61B17/12177 , A61B17/12181 , A61B17/1219 , A61B2017/1205 , A61F2/0077 , A61F2/06 , A61F2/82 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/823 , A61F2002/9155 , A61F2002/91558 , A61F2210/0076 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/006 , A61F2230/0069 , A61F2230/0076
摘要： Devices for treatment of a patient's vasculature are described. The device includes a first hub, a second hub, a support structure including a plurality of struts disposed between the first hub and the second hub, and a layer of material disposed over the plurality of struts. The support structure has a low profile, radially constrained state with an elongated tubular configuration suitable for delivery from a microcatheter. The support structure also has an expanded state, a smooth outer surface, and has an axially shortened configuration relative to the radially constrained state. The layer of material may be made from acrylic, silk, silicone, polyvinyl alcohol, polypropylene, polyester, PolyEtherEther Ketone (PEEK), polytetrafluoroethylene (PTFE), polycarbonate urethane (PCU), or polyurethane (PU). The support structure may be formed from a slotted tubular member.
摘要翻译：描述了用于治疗患者脉管系统的装置。所述装置包括第一轮毂，第二轮毂，支撑结构，所述支撑结构包括设置在所述第一轮毂和所述第二轮毂之间的多个支杆以及设置在所述多个支柱上的材料层。支撑结构具有低轮廓的径向约束状态，其具有适合于从微导管输送的细长管状构造。支撑结构还具有膨胀状态，光滑的外表面，并且相对于径向约束状态具有轴向缩短的构造。材料层可以由丙烯酸，丝，硅酮，聚乙烯醇，聚丙烯，聚酯，聚醚醚酮（PEEK），聚四氟乙烯（PTFE），聚碳酸酯聚氨酯（PCU）或聚氨酯（PU）制成。支撑结构可以由开槽的管状构件形成。

5. 发明申请

US20150150563A1 FILAMENTARY DEVICES FOR TREATMENT OF VASCULAR DEFECTS 审中-公开
公开(公告)号：US20150150563A1
公开(公告)日：2015-06-04
申请号：US14577923
申请日：2014-12-19
申请人： Sequent Medical Inc.
发明人： Philippe Marchand , Brian J. Cox , Robert F. Rosenbluth
IPC分类号： A61B17/12
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12145 , A61B17/12177 , A61B17/1219 , A61B2017/00526 , A61B2017/00867 , A61B2017/12054 , A61B2017/12068 , A61M29/02 , A61M2025/105
摘要： Devices and methods for treatment of a patient's vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments may include a permeable shell configured to occlude blood flow therethrough.

6. 发明授权

US11179159B2 Methods and devices for treatment of vascular defects 有权
公开(公告)号：US11179159B2
公开(公告)日：2021-11-23
申请号：US15595660
申请日：2017-05-15
申请人： SEQUENT MEDICAL, INC.
发明人： Brian J. Cox , Dean Schaefer , Robert F. Rosenbluth
IPC分类号： A61F2/91 , A61F2/915 , A61F2/06 , A61F2/86 , A61F2/82 , A61F2/90 , A61F2/00 , A61B17/12
摘要： Methods of implanting a device in the lumen of a blood vessel are described. The method includes providing a microcatheter and a device. The device includes a first hub, a second hub, a support structure including a plurality of struts disposed between the first hub and the second hub, and a layer of material disposed over the plurality of struts. The support structure has a low profile, radially constrained state with an elongated tubular configuration suitable for delivery from a microcatheter. The support structure also has an expanded state, a smooth outer surface, and has an axially shortened configuration relative to the radially constrained state. The microcatheter is advanced to a region of interest within the blood vessel. The support structure is advanced through the lumen of and out the distal end of the microcatheter where it expands to the expanded state.

7. 发明申请

US20190218696A1 BRAIDING MECHANISM AND METHODS OF USE 审中-公开
公开(公告)号：US20190218696A1
公开(公告)日：2019-07-18
申请号：US16287878
申请日：2019-02-27
申请人： SEQUENT MEDICAL, INC.
发明人： James M. Thompson , Brian J. Cox , Robert Rosenbluth , Philippe Marchand , John Nolting , Darrin J. Kent , Tan Q. Dinh , Hung P. Tran , James A. Milburn
IPC分类号： D04C3/40 , D04C1/12 , D04C1/02 , D04C3/42 , D04C1/00 , D04C1/06 , D04C3/48
CPC分类号： D04C3/40 , D04C1/00 , D04C1/02 , D04C1/06 , D04C1/12 , D04C3/42 , D04C3/48 , D10B2509/04
摘要： Methods of braiding using a braiding mechanism are described. The braiding machine includes first and second annular members, the second annular member being concentric with the first annular member. A mandrel extends perpendicularly to and intersects a horizontal plane defined by a substantially circular region of the second annular member substantially at the center of the circular region. Each of the annular members has a plurality of tubular guide wires slideably mounted thereon and a plurality of wires extend from the mandrel through each of the tubular wire guides. The first annular member rotates circumferentially relative to the second annular member. The first plurality of tubular wire guides slides radially inward to align with the second annular member, and the second plurality of tubular wire guides slides radially outward so as to align with the first annular member.

8. 发明申请

US20160045201A1 BLOOD FLOW DISRUPTION DEVICES AND METHODS FOR THE TREATMENT OF VASCULAR DEFECTS 审中-公开
标题翻译：血液流量破坏装置及治疗血管缺损的方法
公开(公告)号：US20160045201A1
公开(公告)日：2016-02-18
申请号：US14926423
申请日：2015-10-29
申请人： Sequent Medical, Inc.
发明人： Robert Rosenbluth , Brian J. Cox
IPC分类号： A61B17/12 , A61F2/90 , A61F2/962 , A61F2/07
CPC分类号： A61B17/12113 , A61B17/12036 , A61B17/12118 , A61B17/12168 , A61B17/12172 , A61B17/12177 , A61B2017/00004 , A61B2017/00477 , A61B2017/00526 , A61B2017/00867 , A61F2/07 , A61F2/90 , A61F2/962 , A61F2002/075 , A61F2002/077 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0033 , A61F2220/005 , A61F2220/0058 , A61F2230/0006 , A61F2230/0065 , A61F2250/0014 , A61F2250/0036 , D04C1/06 , D04C3/48 , D10B2509/06
摘要： A blood flow disruption device for embolizing blood flowing into a vascular defect between a proximal vascular segment and a distal vascular segment, wherein the device includes a porous inner flow disruption element configured to extend through the defect between the proximal vascular segment and the distal vascular segment, whereby a first portion of the blood flowing into the inner flow disruption element from the proximal vascular segment is directed to flow into the defect and a second portion of the blood flowing into the inner flow disruption element is directed to flow into the distal vascular segment. A porous outer flow disruption element coaxially surrounds the inner flow disruption element and is radially expansible from a collapsed state to an expanded state. The outer flow disruption element, in its expanded state, promotes sufficient hemostasis of the first portion of the blood within the defect to embolize the defect.
摘要翻译：一种血流破坏装置，用于栓塞流入近端血管段和远侧血管段之间的血管缺损的血液，其中所述装置包括多孔内部流动破坏元件，其构造成延伸穿过近端血管段和远侧血管段之间的缺陷由此，从近端血管段流入内部流动破坏元件的血液的第一部分被引导流入缺陷，并且流入内部流动破坏元件的血液的第二部分被引导流入远端血管段。多孔外流破坏元件同轴地围绕内部流动破坏元件并且可以从折叠状态径向扩展到膨胀状态。处于其膨胀状态的外部流动破坏元件促进缺陷中血液的第一部分的充分止血以使缺陷栓塞。

9. 发明申请

US20200281603A1 FILAMENTARY DEVICES FOR TREATMENT OF VASCULAR DEFECTS 审中-公开
公开(公告)号：US20200281603A1
公开(公告)日：2020-09-10
申请号：US16803515
申请日：2020-02-27
申请人： SEQUENT MEDICAL, INC.
发明人： Philippe Marchand , Brian J. Cox , Robert F. Rosenbluth
IPC分类号： A61B17/12 , A61M29/02
摘要： Methods and devices for treatment of a patient's cerebral aneurysm is described. The device includes a permeable shell having a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments that are woven together to form a mesh. The proximal ends of each of the plurality of filaments are gathered by a proximal hub and the distal ends of each of the plurality of filaments are gathered by a distal hub. The proximal portion of the permeable shell includes a swellable polymer. The method includes advancing the implant in a microcatheter to a region of interest in the cerebral vasculature, deploying the implant within the cerebral aneurysm, and withdrawing the microcatheter from the region of interest after deploying the implant.

10. 发明授权

US10238393B2 Multiple layer filamentary devices for treatment of vascular defects 有权
公开(公告)号：US10238393B2
公开(公告)日：2019-03-26
申请号：US15094084
申请日：2016-04-08
申请人： SEQUENT MEDICAL INC.
发明人： Philippe Marchand , Brian J. Cox , Robert F. Rosenbluth , John Nolting , Tan Q. Dinh
IPC分类号： A61M29/00 , A61B17/12 , A61B17/00 , A61B17/22
摘要： Devices and methods for treatment of a patient's vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments may include a permeable shell and inner structure configured to occlude blood flow therethrough.

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