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1. 发明申请

US20100303746A1 GRINDING AIDES FOR MICRONIZED ORGANIC UV ABSORBERS 审中-公开
标题翻译：微波有机紫外线吸收剂研磨助剂
公开(公告)号：US20100303746A1
公开(公告)日：2010-12-02
申请号：US12744495
申请日：2008-11-20
申请人： Sebastien Mongiat , Julie Grumelard , Thomas Ehlis
发明人： Sebastien Mongiat , Julie Grumelard , Thomas Ehlis
IPC分类号： A61K8/49 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/494 , A61K2800/412
摘要： A method of preparing a composition, comprising (a) a micronised insoluble organic UV absorber, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus, in the presence of a grinding aid selected from the groups (b1) carboxylic acids and their salts; (b2) fatty acid esters (b3) alkyl phosphates or phosphoric acid esters; (b4) ethoxylated carboxylic acids or polyethyleneglycol (PEG) esters; (b5) fatty alcohol polyethyleneglycol (PEG) ethers of fatty alcohols; (b6) polyethylene/polypropylene -glycol ethers of saturated or unsaturated C4-C28 fatty acids; (b7) ethoxylated alkylphenols or ethoxylated alkylphenyl ethers; (b8) esters of polyol and mono-, di- or tri-glycerides; (b9) esters of fatty acids and saccharose; (b10) sorbitan mono- and di-esters of saturated and/or unsaturated C6-C22 fatty acids and ethylene oxide groups; and (b11) surfactants which are mainly acting as detergent or cleansing agents.
摘要翻译：一种制备组合物的方法，包括（a）微粉化的不溶性有机UV吸收剂，该方法包括在研磨装置中，在选自以下组的研磨助剂的存在下研磨粗颗粒形式的不溶性有机UV吸收剂（ b1）羧酸及其盐; （b2）脂肪酸酯（b3）磷酸烷基酯或磷酸酯; （b4）乙氧基化羧酸或聚乙二醇（PEG）酯; （b5）脂肪醇的脂肪醇聚乙二醇（PEG）醚; （b6）饱和或不饱和C4-C28脂肪酸的聚乙烯/聚丙二醇醚; （b7）乙氧基化烷基酚或乙氧基化烷基苯基醚; （b8）多元醇和甘油单酯，甘油二酯或甘油酯的酯; （b9）脂肪酸和蔗糖的酯; （b10）饱和和/或不饱和C6-C22脂肪酸和环氧乙烷基团的脱水山梨糖醇单酯和二酯; 和（b11）主要作为洗涤剂或清洁剂的表面活性剂。

2. 发明申请

US20090196894A1 Self Tanning Composition 审中-公开
标题翻译：自晒黑组合物
公开(公告)号：US20090196894A1
公开(公告)日：2009-08-06
申请号：US12227769
申请日：2007-05-21
申请人： Thomas Ehlis , Stefan Müller , Sebastien Mongiat
发明人： Thomas Ehlis , Stefan Müller , Sebastien Mongiat
IPC分类号： A61K9/14 , A61K8/49
CPC分类号： A61Q19/04 , A61K8/044 , A61K8/4973 , A61K8/498 , A61K8/60 , A61K2800/31 , A61K2800/412 , A61K2800/413 , A61Q5/10 , A61Q17/04 , B82Y5/00
摘要： Disclosed is a method for the colouration of skin or a keratinic fibre, characterized in that the skin or keratinic fibre is contacted with a formulation containing a dispersion of solid particles of a tanning substance selected from a compound of the formula (I) wherein i is 0 or 1 and each of R1, R2, R3, R4, R5, R6, R7, R8 independently of each other is selected from group consisting of hydrogen, OH, C1-C6alkyl, C1-C6hydroxyalkyl and C2-C6al-kenyl; in an organic liquid of low polarity or non-polar organic liquid.
摘要翻译：公开了一种使皮肤或角质纤维着色的方法，其特征在于使皮肤或角质纤维与含有鞣制物质的固体颗粒分散体的制剂接触，所述鞣制物质的分散体选自式（I）的化合物，其中i是 R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8彼此独立地选自氢，OH，C 1 -C 6烷基，C 1 -C 6羟烷基和C 2 -C 6α-烯基; 在低极性的有机液体或非极性有机液体中。

3. 发明申请

US20090060853A1 Aminophenylbenzothiazole compounds 审中-公开
公开(公告)号：US20090060853A1
公开(公告)日：2009-03-05
申请号：US12284044
申请日：2008-09-18
申请人： Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
发明人： Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
IPC分类号： A61K8/49 , C07D277/62 , C07D417/10 , A61Q17/04
CPC分类号： A61K8/49 , A61K8/893 , A61K8/894 , A61Q17/04 , C07D277/66
摘要： The Use, as a UV filter, of a compound of formula R1 and R2 are each independently of the other hydrogen; unsubstituted or halo-, amino-, mono- or di-C1-C5alkylamino-, cyano- or C1-C5alkoxy-substituted C1-C22alkyl, C5-C10cycloalkyl, carboxy-C1-C22alkyl, carboxy-C6-C10aryl, C6-C10aryl, C6-C10aryl-C1-C5alkyl; carbamoyl; or sulfamoyl; or R1 and R2, together with the nitrogen atom linking them, form a 5- to 7-membered heterocyclic radical; and R3 is hydrogen; or C1-C22alkyl; and R4 is hydrogen; hydroxy; C1-C22alkyl; or C1-C22alkoxy; is described. The compounds of formula (1) are suitable especially as UV filters in cosmetic preparations.

4. 发明申请

US20050175554A1 Aminophenylbenzothiazole compounds 审中-公开
标题翻译：氨基苯基苯并噻唑化合物
公开(公告)号：US20050175554A1
公开(公告)日：2005-08-11
申请号：US10511852
申请日：2003-04-14
申请人： Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
发明人： Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
IPC分类号： A61K8/00 , A61K8/49 , A61K8/893 , A61K8/894 , A61K8/898 , A61K8/92 , A61K31/428 , A61P17/16 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q5/02 , A61Q17/04 , A61Q19/00 , C07D277/66 , A61K7/42 , C07D277/60
CPC分类号： A61K8/49 , A61K8/893 , A61K8/894 , A61Q17/04 , C07D277/66
摘要： The Use, as a UV filter, of a compound of formula (I), wherein R1 and R2 are each independently of the other hydrogen; unsubstituted or halo-, amino-, mono- or di-C1-C5alkylamino-, cyano- or C1-C5alkoxy-substituted C1-C22alkyl, C5-C10cycloalkyl, carboxy-C1-C22alkyl, carboxy-C6-C10aryl, C6-C10aryl, C6-C10aryl-C1-C5alkyl; carbamoyl; or sulfamoyl; or R1 and R2, together with the nitrogen atom linking them, form a 5- to 7-membered heterocyclic radical; and R3 is hydrogen; or C1-C22alkyl; and R4 is hydrogen; hydroxy; C1-C22alkyl; or C1-C22alkoxy; is described. The compounds of formula (I) are suitable especially as UV filters in cosmetic preparations.
摘要翻译：用作UV过滤器的式（I）化合物，其中R 1和R 2各自独立于另一个氢; 未取代的或卤代，氨基 - ，单 - 或二-C 1 -C 5烷基氨基 - ，氰基 - 或C 1 -C 1 - C 5烷氧基取代的C 1 -C 22烷基，C 5 -C 10烷基，C 5 -C 20烷基，环烷基，羧基-C 1 -C 22烷基，羧基-C 6 -C 10芳基，C 1 -C 6烷基， C 6 -C 10芳基，C 6 -C 10芳基-C 1 - C 5烷基; 氨基甲酰基; 或氨磺酰; 或R 1和R 2 2与连接它们的氮原子一起形成5-至7-元杂环基; 和R 3是氢; 或C 1 -C 22烷基; 并且R 4是氢; 羟基; C 1 -C 22烷基; C 1 -C 12烷基; 或C 1 -C 22烷氧基; 被描述。式（I）的化合物特别适用于化妆品制剂中的UV过滤器。

5. 发明申请

US20090068129A1 Aminophenylbenzothiazole compounds 审中-公开
标题翻译：氨基苯基苯并噻唑化合物
公开(公告)号：US20090068129A1
公开(公告)日：2009-03-12
申请号：US12284043
申请日：2008-09-18
申请人： Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
发明人： Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
IPC分类号： A61K8/49 , C07D277/66
CPC分类号： A61K8/49 , A61K8/893 , A61K8/894 , A61Q17/04 , C07D277/66
摘要： The Use, as a UV filter, of a compound of formula R1 and R2 are each independently of the other hydrogen; unsubstituted or halo-, amino-, mono- or di-C1-C5alkylamino-, cyano- or C1-C5alkoxy-substituted C1-C22alkyl, C5-C10cycloalkyl, carboxy-C1-C22alkyl, carboxy-C6-C10aryl, C6-C10aryl, C6-C10aryl-C1-C5alkyl; carbamoyl; or sulfamoyl; or R1 and R2, together with the nitrogen atom linking them, form a 5- to 7-membered heterocyclic radical; and R3 is hydrogen; or C1-C22alkyl; and R4 is hydrogen; hydroxy; C1-C22alkyl; or C1-C22alkoxy; is described. The compounds of formula (1) are suitable especially as UV filters in cosmetic preparations.
摘要翻译：使用式R 1和R 2的化合物作为UV过滤器各自独立于另一个氢; 未取代或卤代，氨基 - ，单 - 或二-C 1 -C 5烷基氨基 - ，氰基 - 或C 1 -C 5烷氧基取代的C 1 -C 22烷基，C 5 -C 10环烷基，羧基-C 1 -C 22烷基，羧基-C 6 -C 10芳基，C 6 -C 10芳基， C 6 -C 10芳基-C 1 -C 5烷基; 氨基甲酰基; 或氨磺酰; 或R 1和R 2与连接它们的氮原子一起形成5-至7-元杂环基; 并且R 3是氢; 或C 1 -C 22烷基; R4为氢; 羟基; C 1 -C 22烷基; 或C 1 -C 22烷氧基; 被描述。式（1）的化合物特别适用于化妆品制剂中的UV过滤器。

6. 发明申请

US20090156563A1 Glucan Compositions 审中-公开
标题翻译：葡聚糖组合物
公开(公告)号：US20090156563A1
公开(公告)日：2009-06-18
申请号：US12085271
申请日：2006-11-20
申请人： Werner Baschong , Sebastien Mongiat , Dietmar Ochs
发明人： Werner Baschong , Sebastien Mongiat , Dietmar Ochs
IPC分类号： A61K31/60 , A61P17/00
CPC分类号： A61Q11/00 , A61K8/345 , A61K8/347 , A61K8/365 , A61K8/43 , A61K8/73 , A61K31/716 , A61Q1/10 , A61Q1/14 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08
摘要： A cosmetic or pharmaceutical composition is provided comprising: a) 0.001 to less than 0.2% by weight, based on the weight of the total composition, of a scleroglucan having a mean molecular weight of 1×106 to 12×106; b) a cosmetically or pharmaceutically acceptable carrier; and, optionally, c) lactic acid, a lactate and/or pentanediol. The composition shows advantageous effects, such as moisturization of skin or mucosa, and has an antiaging and revitalizing effect on the skin. When combined with a certain bactericide as explained in claim 1, compositions containing native polysaccharides of the glucan class in general, especially of the scleroglucan as of component a), are well suitable to reduce the number of bacteria in mucosal or oral environments and minimise adhesion, while retaining a pleasant feeling on the mucosa or gingiva. Plaque thus can be efficiently prevented or removed.
摘要翻译：提供了一种化妆品或药物组合物，其包含：a）以总组合物的重量计0.001至小于0.2重量％的平均分子量为1×10 6至12×10 6的硬皮葡聚糖; b）美容或药学上可接受的载体; 和任选地，c）乳酸，乳酸盐和/或戊二醇。该组合物显示出有益的效果，例如皮肤或粘膜的保湿，并且对皮肤具有抗衰老和振兴作用。当与根据权利要求1所述的某种杀菌剂组合时，含有葡聚糖类的天然多糖的组合物通常特别是组分a）的硬化葡聚糖是非常适合于减少粘膜或口腔环境中细菌的数量并最小化粘附同时保持对粘膜或牙龈的愉悦感。因此可以有效地防止或去除斑块。

7. 发明申请

US20100111884A1 UV ABSORBER FORMULATIONS 审中-公开
标题翻译：紫外线吸收剂配方
公开(公告)号：US20100111884A1
公开(公告)日：2010-05-06
申请号：US12520894
申请日：2007-12-21
申请人： Stephanie Acker , Sebastien Mongiat
发明人： Stephanie Acker , Sebastien Mongiat
IPC分类号： A61K8/49 , A61Q17/04
CPC分类号： A61K8/4966 , A61K8/046 , A61K8/42 , A61Q1/02 , A61Q1/06 , A61Q1/12 , A61Q17/04 , A61Q19/005
摘要： Disclosed is a UV filter composition comprising (a) an organic UV absorber of formula (1), wherein R1 and R2, independently of one another, are C3-C18alkyl; C2-C18alkenyl; a radical of the formula —CH2—CH(OH)—CH2—O-T1; or R1 and R2 are a radical of the formula (4a); R7 is a direct bond; a straight-chain or branched C1-C4alkylene radical or a radical of the formula (I) or (II); R8, R9 and R10, independently of one another, are C1-C18alkyl; C1-C18alkoxy or a radical of the formula (III); R11 is C1-C5 alkyl; m1 is a number from 1 to 4; p1 is 0; or a number from 1 to 5; A1 is a radical of the formula (1b), (1c) or (1d); R3 is hydrogen; C1-C10alkyl; —(CH2CHR5—O)n1-T2; or —CH2—CH(—OH)—CH2—O-T2; R4 is hydrogen; M; C1-C5alkyl; or —(CH2)m2—O-T3; R5 is hydrogen; or methyl; T1, T2 and T3 independently from each other are hydrogen; or C1-C18alkyl; Q1 is C1-C18alkyl, M is a metal cation; m2 is 1 to 4; and n1 is 1-16, (b) dimethyl capramide, (c) a cosmetically acceptable carrier; and water.
摘要翻译：公开了一种UV滤光组合物，其包含（a）式（1）的有机UV吸收剂，其中R 1和R 2彼此独立地为C 3 -C 18烷基; C 2 -C 18烯基; 式-CH 2 -CH（OH）-CH 2 -O-T 1的基团; 或者R1和R2是式（4a）的基团; R7是直接的债券; 直链或支链的C 1 -C 4亚烷基或式（I）或（II）的基团; R 8，R 9和R 10彼此独立地为C 1 -C 18烷基; C 1 -C 18烷氧基或式（III）的基团; R11是C1-C5烷基; m1是从1到4的数字; p1为0; 或从1到5的数字; A1是式（1b），（1c）或（1d）的基团; R3是氢; C1-C10烷基; - （CH 2 CHR 5 -O）n1-T2; 或-CH 2 -CH（-OH）-CH 2 -O-T 2; R4是氢; M; C1-C5烷基; 或 - （CH2）m2-O-T3; R5是氢; 或甲基; T1，T2和T3彼此独立是氢; 或C 1 -C 18烷基; Q1是C1-C18烷基，M是金属阳离子; m2为1〜4; n1为1-16，（b）癸酰二甲酰胺，（c）化妆品上可接受的载体; 和水。

8. 发明申请

US20100330009A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS 有权
标题翻译：氧化铝类抗氧化剂和紫外线吸收剂
公开(公告)号：US20100330009A1
公开(公告)日：2010-12-30
申请号：US12528357
申请日：2008-02-29
申请人： Barbara Wagner , Sebastien Mongiat , Bernd Herzog , Werner Baschong , Andreas Buthe , Reinhold Ohrlein
发明人： Barbara Wagner , Sebastien Mongiat , Bernd Herzog , Werner Baschong , Andreas Buthe , Reinhold Ohrlein
IPC分类号： A61K8/60 , A61K31/352 , C07D493/04 , A61K31/7048 , C07H17/04 , A61K31/7084 , A61K31/655 , A61K31/4355 , C07D491/04 , A61K8/92 , A61K8/49 , A61P17/00 , A61Q1/06 , A61Q1/10 , A61Q1/12 , A61Q5/00 , A61Q17/04 , C12P19/60 , C12P17/12 , C12P17/06 , A23L3/34
CPC分类号： C07D493/04 , A61K8/4973 , A61K8/498 , A61K2800/522 , A61Q17/04 , C07D491/04
摘要： The present invention relates to derivatives of the 1H-pyrano[4,3-b]benzofuran-1-one structure and their nitrogen analogues which possess powerful antioxidant properties combined with a highly effective UV absorbing functionality in one molecule. These compounds are especially useful in cosmetical and dermatological formulations.
摘要翻译：本发明涉及具有强大抗氧化性能的1H-吡喃并[4,3-b]苯并呋喃-1-酮结构的衍生物及其在一个分子中与高效UV吸收官能团结合的氮类似物。这些化合物在美容和皮肤病学制剂中特别有用。

9. 发明申请

US20080019929A1 Micro-Particulate Organic Uv Absorber Composition 审中-公开
标题翻译：微粒有机Uv吸收剂组合物
公开(公告)号：US20080019929A1
公开(公告)日：2008-01-24
申请号：US11661173
申请日：2005-08-29
申请人： Cyrille Deshayes , Sebastien Mongiat
发明人： Cyrille Deshayes , Sebastien Mongiat
IPC分类号： A61K8/00 , A61Q17/00
CPC分类号： A61K8/342 , A61Q17/04
摘要： Disclosed is a topically applicable water-in-oil (w/o) or water-in-silicone (w/Si) formulation comprising: (a) at least one aqueous phase; (b) at least one fatty phase; (c) an effective UV-photoprotecting composition comprising (c1) 20% to 99% of at least one insoluble micronized organic UV-screening active with a mean particle size ranging from 0.01 μm to 2 μm; and (c2) 0.5% to 80% of at least one primary C6-C28 fatty alcohol. The combination of a micronized organic UV absorber and a specific fatty alcohol allows a maximum of miscibility of micronized organic particles within the continuous oil phase of w/o emulsion wherein the micronized particles are stabilized in the oil phase of the composition. Simultaneously the crystal growth of micronized organic UV absorbers within W/O emulsions is limited or even eliminated.
摘要翻译：公开了一种局部适用的油包水（w / o）或水包硅（w / Si）制剂，其包含：（a）至少一种水相; （b）至少一个脂肪相; （c）有效的UV光保护组合物，其包含20％至99％的至少一种平均粒径为0.01μm至2μm的不溶性微粉化有机UV-筛选活性物质的（c-1）和（c 2/2）0.5％至80％的至少一种C 6 -C 28脂肪醇。微粉化有机UV吸收剂和特定脂肪醇的组合允许在w / o乳液的连续油相中的微粉化有机颗粒的最大混溶性，其中微粉化颗粒在组合物的油相中稳定。同时，W / O乳液中微粉化有机UV吸收剂的晶体生长受到限制或甚至消除。

10. 发明申请

US20050196360A1 Micropigment mixtures 有权
标题翻译：微孔混合物
公开(公告)号：US20050196360A1
公开(公告)日：2005-09-08
申请号：US10503151
申请日：2003-01-23
申请人： Christine Comte , Sebastien Mongiat
发明人： Christine Comte , Sebastien Mongiat
IPC分类号： A61K8/00 , A61K8/29 , A61K8/36 , A61K8/42 , A61K8/49 , A61Q5/00 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61K7/42
CPC分类号： A61K8/29 , A61K8/42 , A61K8/496 , A61Q17/04
摘要： Disclosed is a UV absorber mixture, comprising (a) 1% to 60% of a micronised UV broadband absorber of formula: Formula (I); wherein R1 is C1-C12alkyl; or phenyl-substituted C1-C12alkyl; and (b) 1% to 60% by weight of a water dispersible and/ir oil-dispersible coated titanium di-oxide. The UV absorber mixture shows synergistic effect with respect to the UPF.
摘要翻译：公开了一种UV吸收剂混合物，其包含（a）1％至60％的式（I）的微粉化UV宽带吸收剂; 其中R 1是C 1 -C 12烷基; 或苯基取代的C 1 -C 12烷基; 和（b）1重量％至60重量％的水分散性和/或油性分散涂层的二氧化钛。紫外线吸收剂混合物对UPF显示出协同效应。

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