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1. 发明申请

US20090252652A1 Apparatus And Method For Handling Fluids For Analysis 有权
公开(公告)号：US20090252652A1
公开(公告)日：2009-10-08
申请号：US12486074
申请日：2009-06-17
申请人： Scott Safar , Stephen Herchenbach , Chadwick M. Dunn , Charles Michael Galitz , Julius J. Toth , Ronald E. Kukla , Michael G. Lowery , Eric B. Shain
发明人： Scott Safar , Stephen Herchenbach , Chadwick M. Dunn , Charles Michael Galitz , Julius J. Toth , Ronald E. Kukla , Michael G. Lowery , Eric B. Shain
IPC分类号： B01L3/00
CPC分类号： G01N35/1004 , B01L3/50255 , B01L3/5082 , B01L99/00 , B01L2200/0668 , B01L2400/049 , B01L2400/0655 , B01L2400/0688 , G01N35/0098 , G01N35/1065 , Y10T137/0391 , Y10T137/0396 , Y10T436/25375 , Y10T436/2575
摘要： A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.

2. 发明授权

US08409528B2 Apparatus and method for handling fluids for analysis 失效
标题翻译：处理流体用于分析的装置和方法
公开(公告)号：US08409528B2
公开(公告)日：2013-04-02
申请号：US10865207
申请日：2004-06-10
申请人： Scott Safar , Stephen Herchenbach , Chadwick M. Dunn , Charles Michael Galitz , Julius J. Toth , Ronald E. Kukla , Michael G. Lowery , Eric B. Shain
发明人： Scott Safar , Stephen Herchenbach , Chadwick M. Dunn , Charles Michael Galitz , Julius J. Toth , Ronald E. Kukla , Michael G. Lowery , Eric B. Shain
IPC分类号： B01L3/00
CPC分类号： G01N35/1004 , B01L3/50255 , B01L3/5082 , B01L99/00 , B01L2200/0668 , B01L2400/049 , B01L2400/0655 , B01L2400/0688 , G01N35/0098 , G01N35/1065 , Y10T137/0391 , Y10T137/0396 , Y10T436/25375 , Y10T436/2575
摘要： A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.
摘要翻译：具有底部排放开口的反应容器，其通过流体的表面张力支撑选定的未压缩流体的头部。装置处理区域包括支撑隔离排列的反应容器，与其支撑的容器的排放开口连通的通道，以及用于选择性地通过排放开口排出流体的压力源。通常，水平条形磁体被支撑用于在容器列之间选择的垂直运动。分配头具有可选择性地定位在X选择的反应容器上的X个排出口。计量泵机构选择性地将X选定量的流体计量为批量供应（其中X为至少四个），并且选择性地将计量的所选量通过排放开口泵送到选定的反应容器。还包括使用压力源从容器中抽取流体并移动磁体以形成分析物颗粒的方法。

3. 发明授权

US08298498B2 Apparatus and method for handling fluids for analysis 有权
标题翻译：处理流体用于分析的装置和方法
公开(公告)号：US08298498B2
公开(公告)日：2012-10-30
申请号：US11491214
申请日：2006-07-21
申请人： Scott Safar , Stephen Herchenbach
发明人： Scott Safar , Stephen Herchenbach
IPC分类号： B01L9/00
CPC分类号： B01L3/0234 , B01J2219/00585 , B01L3/545 , B01L9/06 , B01L2200/021 , B01L2200/025 , B01L2200/0642 , B01L2200/14 , B01L2200/16 , B01L2300/021 , G01N35/00732 , G01N35/0099 , G01N35/028 , G01N35/04 , G01N35/1002 , G01N35/1011 , G01N35/1067 , G01N35/1083 , G01N2035/00772 , G01N2035/00801 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： An apparatus and method of loading reagent in a specimen handling device is disclosed, where the apparatus includes a deck with a plurality of positions defined thereon and each of the positions visually marked by a distinct one of a first set of icons. Each of a plurality of trays is removably securable to a selected one of the positions on the deck and includes the distinct one of the first set of icons visually marking the selected one of the positions. Reagent receptacles on each of the plurality of trays are visually marked by a distinct one of a second set of icons, and a kit is provided with a plurality of containers with selected reagents therein, each of the containers being visually marked by the distinct one of the second set of icons visually marking the receptacle into which that reagent is to be poured. The fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate. The apparatus may be used in a method including emptying reagents into the reagent receptacles that are visually marked with the same distinct one of the set of icons visually marking the reagent container, and mounting the trays in selected positions in the specimen handling device.
摘要翻译：公开了一种将试剂加载到试样处理装置中的装置和方法，其中装置包括具有限定在其上的多个位置的甲板，并且每个位置由第一组图标中的不同的一个目视标记。多个托盘中的每个托盘可拆卸地固定到甲板上的所选位置之一，并且包括第一组图标中的不同的一个图标，其可视地标记所选择的一个位置。多个托盘中的每个托盘上的试剂容器由第二组图标中的不同的一个目视标记，并且试剂盒在其中设置有多个具有选定试剂的容器，每个容器由视觉上由不同的一个第二组图标可视地标记待倾倒试剂的容器。包括标本样品和试剂的流体在加工过程中在管之间移动，而不会直接通过试剂可能污染的管。该装置可以用于将试剂清空到试剂容器中的方法中，所述试剂容器用视觉上标有试剂容器的视觉标记的一组图标中相同的不同的一个，并且将托盘安装在试样处理装置中的选定位置。

4. 发明申请

US20130065315A1 Apparatus and Method for Handling Fluids for Analysis 有权
标题翻译：处理流体的装置和方法进行分析
公开(公告)号：US20130065315A1
公开(公告)日：2013-03-14
申请号：US13618891
申请日：2012-09-14
申请人： Scott Safar , Stephen Herchenbach
发明人： Scott Safar , Stephen Herchenbach
IPC分类号： G01N33/50
CPC分类号： B01L3/0234 , B01J2219/00585 , B01L3/545 , B01L9/06 , B01L2200/021 , B01L2200/025 , B01L2200/0642 , B01L2200/14 , B01L2200/16 , B01L2300/021 , G01N35/00732 , G01N35/0099 , G01N35/028 , G01N35/04 , G01N35/1002 , G01N35/1011 , G01N35/1067 , G01N35/1083 , G01N2035/00772 , G01N2035/00801 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： An apparatus and method of loading reagent in a specimen handling device is disclosed. Fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate. The apparatus may also include a head adapted to carry selected fluids in pipettes and a reagent receptacle adapted to permit entry of the head.
摘要翻译：公开了一种将试剂加载到试样处理装置中的装置和方法。包括样品样品和试剂的流体在加工过程中在管之间移动，而不会直接通过试剂可能污染的管。该装置还可以包括头部，该头部适用于将选定的流体携带在移液管中，以及适于允许头部进入的试剂容器。

5. 发明申请

US20060081539A1 Structure and method for handling magnetic particles in biological assays 有权
标题翻译：在生物测定中处理磁性颗粒的结构和方法
公开(公告)号：US20060081539A1
公开(公告)日：2006-04-20
申请号：US10512033
申请日：2003-04-25
申请人： Scott Safar , Charles Galitz , Stephen Herchenbach , Chadwick Dunn , Larry McDowell
发明人： Scott Safar , Charles Galitz , Stephen Herchenbach , Chadwick Dunn , Larry McDowell
IPC分类号： C02F1/48 , G01N35/02
CPC分类号： B01L3/5085 , B01D35/06 , B01L3/5082 , B01L9/06 , B01L2300/0848 , B03C1/02 , B03C1/0332 , B03C1/288 , B03C2201/18 , B03C2201/26 , G01N35/0098 , G01N2035/00564 , G01N2035/103 , Y10S436/809 , Y10T436/11 , Y10T436/113332 , Y10T436/25375 , Y10T436/2575
摘要： Magnetic handling structure (1a) comprising a retractable magnet (4) and a probe (3) for the manipulation of magnetic particles in biological samples and methods of handling magnetic particles in biological samples.
摘要翻译：磁性处理结构（1a）包括用于操纵生物样品中的磁性颗粒的可伸缩磁体（4）和探针（3）和处理生物样品中的磁性颗粒的方法。

6. 发明申请

US20050047963A1 Apparatus and method for handling fluids for analysis 失效
标题翻译：处理流体用于分析的装置和方法
公开(公告)号：US20050047963A1
公开(公告)日：2005-03-03
申请号：US10865207
申请日：2004-06-10
申请人： Scott Safar , Stephen Herchenbach , Chadwick Dunn , Charles Galitz , Julius Toth , Ronald Kukla , Michael Lowery , Eric Shain
发明人： Scott Safar , Stephen Herchenbach , Chadwick Dunn , Charles Galitz , Julius Toth , Ronald Kukla , Michael Lowery , Eric Shain
IPC分类号： B01L3/00 , B01L3/14 , B67D99/00 , G01N1/00 , G01N35/00 , G01N35/10
CPC分类号： G01N35/1004 , B01L3/50255 , B01L3/5082 , B01L99/00 , B01L2200/0668 , B01L2400/049 , B01L2400/0655 , B01L2400/0688 , G01N35/0098 , G01N35/1065 , Y10T137/0391 , Y10T137/0396 , Y10T436/25375 , Y10T436/2575
摘要： A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.
摘要翻译：具有底部排放开口的反应容器，其通过流体的表面张力支撑选定的未压缩流体的头部。装置处理区域包括支撑隔离排列的反应容器，与其支撑的容器的排放开口连通的通道，以及用于选择性地通过排放开口排出流体的压力源。通常，水平条形磁体被支撑用于在容器列之间选择的垂直运动。分配头具有可选择性地定位在X选择的反应容器上的X个排出口。计量泵机构选择性地测量选定量的流体的批量供应（其中X是至少四个），并且选择性地将经计量的所选量通过排放开口泵送到选定的反应容器。还包括使用压力源从容器中抽取流体并移动磁体以形成分析物颗粒的方法。

7. 发明授权

US09114392B2 Apparatus and method for handling fluids for analysis 有权
标题翻译：处理流体用于分析的装置和方法
公开(公告)号：US09114392B2
公开(公告)日：2015-08-25
申请号：US13618891
申请日：2012-09-14
申请人： Scott Safar , Stephen Herchenbach
发明人： Scott Safar , Stephen Herchenbach
IPC分类号： B01L3/02 , B01L3/00 , B01L9/06 , G01N35/02 , G01N35/04 , G01N35/00 , G01N35/10
CPC分类号： B01L3/0234 , B01J2219/00585 , B01L3/545 , B01L9/06 , B01L2200/021 , B01L2200/025 , B01L2200/0642 , B01L2200/14 , B01L2200/16 , B01L2300/021 , G01N35/00732 , G01N35/0099 , G01N35/028 , G01N35/04 , G01N35/1002 , G01N35/1011 , G01N35/1067 , G01N35/1083 , G01N2035/00772 , G01N2035/00801 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： An apparatus and method of loading reagent in a specimen handling device is disclosed. Fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate. The apparatus may also include a head adapted to carry selected fluids in pipettes and a reagent receptacle adapted to permit entry of the head.
摘要翻译：公开了一种将试剂加载到试样处理装置中的装置和方法。包括样品样品和试剂的流体在加工过程中在管之间移动，而不会直接通过试剂可能污染的管。该装置还可以包括头部，该头部适用于将选定的流体携带在移液管中，以及适于允许头部进入的试剂容器。

8. 发明申请

US20060258010A1 Apparatus and method for handling fluids for analysis 有权
标题翻译：处理流体用于分析的装置和方法
公开(公告)号：US20060258010A1
公开(公告)日：2006-11-16
申请号：US11491214
申请日：2006-07-21
申请人： Scott Safar , Stephen Herchenbach
发明人： Scott Safar , Stephen Herchenbach
IPC分类号： G01N35/00
CPC分类号： B01L3/0234 , B01J2219/00585 , B01L3/545 , B01L9/06 , B01L2200/021 , B01L2200/025 , B01L2200/0642 , B01L2200/14 , B01L2200/16 , B01L2300/021 , G01N35/00732 , G01N35/0099 , G01N35/028 , G01N35/04 , G01N35/1002 , G01N35/1011 , G01N35/1067 , G01N35/1083 , G01N2035/00772 , G01N2035/00801 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： An apparatus and method of loading reagent in a specimen handling device is disclosed, where the apparatus includes a deck with a plurality of positions defined thereon and each of the positions visually marked by a distinct one of a first set of icons. Each of a plurality of trays is removably securable to a selected one of the positions on the deck and includes the distinct one of the first set of icons visually marking the selected one of the positions. Reagent receptacles on each of the plurality of trays are visually marked by a distinct one of a second set of icons, and a kit is provided with a plurality of containers with selected reagents therein, each of the containers being visually marked by the distinct one of the second set of icons visually marking the receptacle into which that reagent is to be poured. The fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate. The apparatus may be used in a method including emptying reagents into the reagent receptacles that are visually marked with the same distinct one of the set of icons visually marking the reagent container, and mounting the trays in selected positions in the specimen handling device.
摘要翻译：公开了一种将试剂加载到试样处理装置中的装置和方法，其中装置包括具有限定在其上的多个位置的甲板，并且每个位置由第一组图标中的不同的一个目视标记。多个托盘中的每个托盘可拆卸地固定到甲板上的所选位置之一，并且包括第一组图标中的不同的一个图标，其可视地标记所选择的一个位置。多个托盘中的每个托盘上的试剂容器由第二组图标中的不同的一个目视标记，并且试剂盒在其中设置有多个具有选定试剂的容器，每个容器由视觉上由不同的一个第二组图标可视地标记待倾倒试剂的容器。包括标本样品和试剂的流体在加工过程中在管之间移动，而不会直接通过试剂可能污染的管。该装置可以用于将试剂清空到试剂容器中的方法中，所述试剂容器用视觉上标有试剂容器的视觉标记的一组图标中相同的不同的一个，并且将托盘安装在试样处理装置中的选定位置。

9. 发明授权

US07125722B2 Apparatus and method for handling fluids for analysis 有权
公开(公告)号：US07125722B2
公开(公告)日：2006-10-24
申请号：US10360956
申请日：2003-02-07
申请人： Scott Safar , Stephen Herchenbach
发明人： Scott Safar , Stephen Herchenbach
IPC分类号： G01N35/00
CPC分类号： B01L3/0234 , B01J2219/00585 , B01L3/545 , B01L9/06 , B01L2200/021 , B01L2200/025 , B01L2200/0642 , B01L2200/14 , B01L2200/16 , B01L2300/021 , G01N35/00732 , G01N35/0099 , G01N35/028 , G01N35/04 , G01N35/1002 , G01N35/1011 , G01N35/1067 , G01N35/1083 , G01N2035/00772 , G01N2035/00801 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： An apparatus and method of loading reagent in a specimen handling device is disclosed, where the apparatus includes a deck with a plurality of positions defined thereon and each of the positions visually marked by a distinct one of a first set of icons. Each of a plurality of trays is removably securable to a selected one of the positions on the deck and includes the distinct one of the first set of icons visually marking the selected one of the positions. Reagent receptacles on each of the plurality of trays are visually marked by a distinct one of a second set of icons, and a kit is provided with a plurality of containers with selected reagents therein, each of the containers being visually marked by the distinct one of the second set of icons visually marking the receptacle into which that reagent is to be poured. The fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate. The apparatus may be used in a method including emptying reagents into the reagent receptacles that are visually marked with the same distinct one of the set of icons visually marking the reagent container, and mounting the trays in selected positions in the specimen handling device.

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