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    • 4. 发明授权
    • Camshaft rotational phase detecting apparatus and cylinder intake air quantity calculating apparatus for engine
    • 用于发动机的凸轮轴转动相位检测装置和气缸进气量计算装置
    • US06718920B2
    • 2004-04-13
    • US10062566
    • 2002-02-05
    • Masato HoshinoYoshiaki YoshiokaTetsuya Iwasaki
    • Masato HoshinoYoshiaki YoshiokaTetsuya Iwasaki
    • F01L134
    • F01L1/34
    • A camshaft rotational phase detecting apparatus for an engine provided with a variable valve timing control mechanism which controls a camshaft rotational phase of an engine valve to a target camshaft rotational phase by varying a rotational phase of a camshaft relative to a crankshaft. The camshaft rotational phase detecting apparatus is configured to detect a camshaft rotational phase as a detected camshaft rotational phase based on a signal from a sensor. In the apparatus, the detected camshaft rotational phase is substituted with a maintained rotational phase for a predetermined period and is substituted with a target camshaft rotational phase after a lapse of the predetermined period, when the camshaft rotational phase is not detected. In the apparatus, the maintained rotational phase is set corresponding to the detected camshaft rotational phase detected before a timing that the camshaft rotational phase is not detected. Additionally, in the apparatus, the predetermined period is set in accordance with an engine temperature.
    • 一种用于发动机的凸轮轴旋转相位检测装置,其具有可变气门正时控制机构,其通过改变凸轮轴相对于曲轴的旋转相位来将发动机气门的凸轮轴转动相位控制到目标凸轮轴转动相位。 凸轮轴转动相位检测装置被配置为基于来自传感器的信号来检测凸轮轴转动相位作为检测到的凸轮轴转动相位。 在该装置中,检测到的凸轮轴旋转相位被保持的旋转相位取代预定时间段,并且在未检测到凸轮轴转动相位之后经过预定时间段后被目标凸轮轴转动相位代替。 在该装置中,对应于在没有检测到凸轮轴旋转相位的定时之前检测到的检测到的凸轮轴转动相位来设定保持的旋转相位。 此外,在该装置中,根据发动机温度来设定预定时间。
    • 5. 发明授权
    • Knock control system
    • 敲门控制系统
    • US06736109B2
    • 2004-05-18
    • US10444731
    • 2003-05-27
    • Masato Hoshino
    • Masato Hoshino
    • F02P500
    • G01L23/225
    • A knock control system is configured to precisely determine situations in which the knock signal cannot be detected and to suppress the occurrence of reductions in fuel efficiency, exhaust performance, and output performance. The knock control system has a knock sensor that detects an engine knocking condition to produce a knock signal of a prescribed level and a variable valve mechanism that can change the intake valve closing timing. Based on the ratio of the estimated knock signal during knocking to the estimated noise signal during no knocking, the knock control system determines if an accurate knock signal can be detected. The knock control system also determines if the valve seating position corresponding to the intake valve closing timing is within the knock detection interval and, if so, the estimated mechanical noise component of the estimated noise signal is updated.
    • 敲击控制系统被配置为精确地确定不能检测到爆震信号的情况,并且抑制燃料效率,排气性能和输出性能的降低的发生。 爆震控制系统具有检测发动机爆震条件以产生规定级别的爆震信号的爆震传感器以及可改变进气门关闭正时的可变气门机构。 基于爆震期间估计的爆震信号与无爆震期间估计的噪声信号的比率,爆震控制系统确定是否能够检测到准确的爆震信号。 敲击控制系统还确定与进气门关闭正时相对应的阀座位置是否在爆震检测间隔内,如果是,则更新估计噪声信号的估计机械噪声分量。
    • 6. 发明授权
    • Resin composition for solder resist ink
    • 阻焊油墨用树脂组合物
    • US4888269A
    • 1989-12-19
    • US231606
    • 1988-08-11
    • Yoneji SatoMasato HoshinoSeiichi KitazawaTadashi Yasuda
    • Yoneji SatoMasato HoshinoSeiichi KitazawaTadashi Yasuda
    • B23K35/22G03F7/032H05K3/28
    • G03F7/032B23K35/224H05K3/287H05K2203/0783
    • A resin composition for use in a solder resist ink, said composition comprising as essential ingredients(A) an epoxy vinyl ester resin solution obtained by dissolving (A-a) an epoxy vinyl ester resin obtained by reacting a phenol novolak-type epoxy resin and/or a cresol novolak-type epoxy resin with 0.40 to 0.85 mol, per epoxy group of the epoxy resin, of an unsaturated monobasic acid in (A-b) an organic and/or (A-c) at least one photopolymerizable polyfunctional vinyl monomer selected from the group consisting trifunctional or higher polyoxyalkylene glycol poly(meth)acrylates, poly(meth)acrylates of polyoxyalkyl isocyanurates and poly(meth)acrylates of acetal compounds,(B) a photopolymerization initiator, and(C) a curing agent of an amino group and/or imino group-containing epoxy resin.
    • 一种用于阻焊油墨的树脂组合物,所述组合物包含作为(A)环氧乙烯基酯树脂溶液的必要成分(A),其通过将(Aa)通过使苯酚酚醛清漆型环氧树脂反应获得的环氧乙烯基酯树脂和/或 (Ab)有机和/或(Ac)至少一种可光聚合的多官能乙烯基单体的不饱和一元酸的环氧树脂为0.40〜0.85摩尔的甲酚酚醛清漆型环氧树脂,其选自: 三官能以上聚氧亚烷基二醇聚(甲基)丙烯酸酯,聚氧乙烯异氰脲酸酯的聚(甲基)丙烯酸酯和缩醛化合物的聚(甲基)丙烯酸酯,(B)光聚合引发剂,和(C)氨基和/或 含亚氨基的环氧树脂。
    • 7. 发明申请
    • COMPOSITION FOR MUCOSAL ADMINISTRATION CONTAINING AGENT FOR ENHANCING MUCOSAL ABSORPTION OF PEPTIDE DRUG, AND ADMINISTRATION METHOD THEREOF
    • 用于增强胶原蛋白吸收肽肽药物的包含药物的组合物的组合物及其施用方法
    • US20110165195A1
    • 2011-07-07
    • US12602576
    • 2008-06-27
    • Masuo KondohHiroshi UchidaTakeshi HanadaMasato Hoshino
    • Masuo KondohHiroshi UchidaTakeshi HanadaMasato Hoshino
    • C07K14/33A61K38/02A61K38/16
    • A61K38/29A61K9/0019A61K9/0043A61K9/0073A61K38/164A61K38/2214A61K38/25A61K47/42A61K2300/00
    • A mucosal absorption-enhancing agent is provided that enables oral, nasal or pulmonary administration of peptide drugs whose administration route has heretofore been limited to the injections due to their poor absorption from the mucosa. Specifically, the mucosal absorption of peptide drugs via intestinal, pulmonary or nasal route can be enhanced by allowing the peptide drugs with the C-terminal fragment (C-CPE) of an enterotoxin (CPE) produced by the bacterium Clostridium perfringens of the genus Clostridium, in particular with the C-CPE or its mutants resulting from the substitution and/or deletion of one or several amino acid residues of the C-CPE to act thereon. The composition for mucosal administration of the present invention significantly enhances absorption of peptide drugs, such as human parathyroid hormone hPTH(1-34), human ghrelin and human motilin, through the mucosa of small intestine, lung, nasal cavity and other mucosa. Also, unlike any of the conventional mucosal absorption-enhancers, the composition for mucosal administration of the present invention does not cause tissue damage and is therefore highly safe for use.
    • 提供了一种粘膜吸收增强剂,其能够口服,鼻或肺给予肽药物,其药物途径迄今为止由于其对粘膜的吸收差而限于注射。 具体地说,可以通过使具有由梭菌属产气荚膜梭菌(Clostridium perfringens)产生的肠毒素(CPE)的C末端片段(CPE)的C末端片段(CPE)的肽药物与肽药物的粘膜吸收, 特别是C-CPE或其由C-CPE的一个或几个氨基酸残基的取代和/或缺失产生的突变体作用于其上。 本发明的粘膜给药组合物通过小肠,肺,鼻腔和其他粘膜的粘膜显着增强肽药物如人甲状旁腺激素hPTH(1-34),人生长素释放肽和人胃动素的吸收。 此外,与任何常规的粘膜吸收增强剂不同,本发明的粘膜给药用组合物不会引起组织损伤,因此高度安全使用。
    • 8. 发明授权
    • Setting minimum spark advance for best torque in an internal combustion engine
    • 在内燃机中设置最佳扭矩的最小火花提前
    • US06557526B1
    • 2003-05-06
    • US10263855
    • 2002-10-04
    • Masato Hoshino
    • Masato Hoshino
    • F02P500
    • F02D35/02F02D35/026F02D35/028F02D37/02F02D2041/1433F02P5/1502F02P5/1512Y02T10/46
    • An internal combustion engine (1) causes an air-fuel mixture produced in a combustion chamber (23) to burn by means of ignition using a spark plug (24). A programmable controller (20) calculates a reaction probability expressing the combustibility of the air-fuel mixture inside the combustion chamber (23) and the combustion rate of the air-fuel mixture on the basis of the operating conditions of the engine 1 (S13, S27, S32). An air-fuel mixture combustion period is calculated on the basis of the volume of the combustion chamber at the combustion start timing, the reaction probability, and the combustion rate (S29, S34). On the basis of this combustion period, a target ignition timing of the spark plug (24) can be accurately set under a small calculation load.
    • 内燃机(1)使得在燃烧室(23)中产生的空气燃料混合物通过点火使用火花塞(24)燃烧。 可编程控制器(20)基于发动机1的运行条件计算表示燃烧室(23)内的空气燃料混合物的燃烧性和空气 - 燃料混合物的燃烧速率的反应概率(S13, S27,S32)。 基于燃烧开始时刻的燃烧室的体积,反应概率和燃烧率来计算空燃混合燃烧时间(S29,S34)。 在该燃烧期的基础上,可以在小的计算负荷下精确地设定火花塞(24)的目标点火正时。