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1. 外观设计

USD303007S Electrophoresis sequencing apparatus 失效
公开(公告)号：USD303007S
公开(公告)日：1989-08-22
申请号：US10113
申请日：1987-02-02
申请人： Robert W. Flesher , Kevin J. Barnes , Robert W. Blakesley , Robert W. Lynn
设计人： Robert W. Flesher , Kevin J. Barnes , Robert W. Blakesley , Robert W. Lynn

2. 发明授权

US06170689B2 Collapsible container 失效
标题翻译：可折叠集装箱
公开(公告)号：US06170689B2
公开(公告)日：2001-01-09
申请号：US09464748
申请日：1999-12-16
申请人： Robert W. Flesher , Kevin J. Barnes , Michael Monteleone
发明人： Robert W. Flesher , Kevin J. Barnes , Michael Monteleone
IPC分类号： B65D616
CPC分类号： B65D19/06 , B65D19/18 , B65D2519/00034 , B65D2519/00069 , B65D2519/00159 , B65D2519/00174 , B65D2519/00208 , B65D2519/00268 , B65D2519/00288 , B65D2519/00318 , B65D2519/00338 , B65D2519/00407 , B65D2519/00412 , B65D2519/00422 , B65D2519/00427 , B65D2519/00497 , B65D2519/00527 , B65D2519/00557 , B65D2519/00597 , B65D2519/00621 , B65D2519/00651 , B65D2519/00711 , B65D2519/009 , B65D2519/0091 , B65D2519/00925 , B65D2519/00965 , B65D2519/0099
摘要： A collapsible container includes a substantially rectangular plastic base, a first plastic wall coupled by a first hinge to a first edge of the base, and a second plastic wall coupled by a second hinge to a second edge of the base opposite the first edge of the base. A first corrugated element is folded to form a first corrugated floor portion and a first corrugated wall portion, wherein the first corrugated floor portion is attached to the base so that the first corrugated wall portion is positioned between and adjacent to the first and second plastic walls. The first corrugated wall portion mates with a first lip of the first plastic wall and a first lip of the second plastic wall. Similarly, a second corrugated element is folded to form a second corrugated floor portion and a second corrugated wall portion, wherein the second corrugated floor portion is attached to the base so that the second corrugated wall portion is positioned between and adjacent to the first and second plastic walls, and opposite said first corrugated wall portion. The second corrugated wall portion mates with a second lip of the first plastic wall and a second lip of the second plastic wall. When the container is in a collapsed position, the first and second corrugated wall portions are folded in toward the base, and the first and second plastic walls are folded in toward the base and over the folded-in first and second corrugated wall portions.
摘要翻译：可折叠的容器包括基本上矩形的塑料基座，通过第一铰链连接到基座的第一边缘的第一塑料壁，以及通过第二铰链连接到基座的第二边缘的第二塑料壁，基础。第一波纹元件被折叠以形成第一波纹状底板部分和第一波纹壁部分，其中第一波纹底板部分附接到基座，使得第一波纹壁部分位于第一和第二波纹壁部分之间并且邻近第一和第二塑料壁。第一波纹壁部分与第一塑料壁的第一唇缘和第二塑料壁的第一唇缘配合。类似地，第二波纹状元件被折叠以形成第二波纹状底板部分和第二波纹壁部分，其中第二波纹状底板部分附接到基座，使得第二波纹壁部分位于第一和第二波纹壁部分之间塑料壁，和相对的第一波纹壁部分。第二波纹壁部分与第一塑料壁的第二唇缘和第二塑料壁的第二唇缘配合。当容器处于折叠位置时，第一和第二波纹壁部分朝向基部折叠，并且第一和第二塑料壁朝向基部折叠并折叠在折叠的第一和第二波纹壁部分之上。

3. 发明授权

US6143391A One-piece, dual-material suction cup 失效
标题翻译：一体式双材料吸盘
公开(公告)号：US6143391A
公开(公告)日：2000-11-07
申请号：US209297
申请日：1998-12-11
申请人： Kevin J. Barnes , Robert W. Flesher , Michael D. Monteleone
发明人： Kevin J. Barnes , Robert W. Flesher , Michael D. Monteleone
IPC分类号： F16B47/00 , B32B1/04
CPC分类号： F16B47/00 , Y10T428/21 , Y10T428/219 , Y10T428/24008 , Y10T428/24174 , Y10T428/24983
摘要： A one-piece, dual-material suction cup includes an inner face having a concave shape when the cup is inactive (that is, unattached to a surface) and an outer portion having a convex shape when the cup is inactive. The inner and outer portions are formed from different elastic materials. The characteristics of the outer material are selected to exhibit relatively high memory, elasticity and recovery to provide a biasing force on the inner face of the cup to increase the vacuum and enhance attachment. The characteristics of the inner material are selected to exhibit conformity, compliance and softness as compared to the outer material. Such characteristics enhance mating and sealing with a surface to which the cup is to be attached. The inner and outer portions are permanently bonded together to form the one-piece suction cup.
摘要翻译：一体式双材料吸盘包括当杯不活动时（即，未附着于表面）的具有凹形形状的内表面和当杯不活动时具有凸形形状的外部部分。内部和外部由不同的弹性材料形成。选择外部材料的特性以显示相对高的记忆力，弹性和恢复性，以在杯的内表面上提供偏压力以增加真空度并增强附着力。与外部材料相比，选择内部材料的特性以表现出一致性，顺应性和柔软性。这种特征增强了与杯子要附着的表面的配合和密封。内部和外部部分永久地结合在一起以形成一体式吸盘。

4. 发明授权

US5213766A Liquid collecting apparatus for sample testing 失效
标题翻译：用于样品测试的液体收集装置
公开(公告)号：US5213766A
公开(公告)日：1993-05-25
申请号：US693654
申请日：1991-04-30
申请人： Robert W. Flesher , Kevin J. Barnes
发明人： Robert W. Flesher , Kevin J. Barnes
IPC分类号： B01L3/00 , G01N35/00
CPC分类号： B01L3/5025 , G01N2035/00118 , Y10S435/809 , Y10S436/809 , Y10T436/110833 , Y10T436/2575
摘要： For collecting a batch of liquid samples, such as in the laboratory testing of body fluids, there is provided a collecting sheet having an array of resiliently deflectable fingers formed in the sheet. The fingers can be deflected out of the plane of the sheet to dip into respective liquid containers such as wells in a microtiter plate so as to absorb liquid samples therefrom. When released, the fingers snap back into the plane of the sheet retaining the liquid samples therein.
摘要翻译：为了收集一批液体样品，例如在体液的实验室测试中，提供了具有形成在片材中的可弹性偏转的指状物的阵列的收集片。指状物可以从片材的平面偏转以浸入微量滴定板中的相应的液体容器如孔中，以从其中吸收液体样品。当释放时，手指卡回到保持其中的液体样品的片材的平面中。

5. 发明授权

US4773984A Vertical gel slab electrophoresis apparatus 失效
标题翻译：立式凝胶板电泳仪
公开(公告)号：US4773984A
公开(公告)日：1988-09-27
申请号：US009708
申请日：1987-02-02
申请人： Robert W. Flesher , Kevin J. Barnes , Robert W. Lynn , Robert W. Blakesley
发明人： Robert W. Flesher , Kevin J. Barnes , Robert W. Lynn , Robert W. Blakesley
IPC分类号： G01N27/447 , G01N27/28 , G01N27/26
CPC分类号： G01N27/44704 , G01N27/44756
摘要： A vertical gel slab electrophoresis apparatus is disclosed comprised of a vertically oriented gel slab arranged between upper and lower buffer solution reservoirs. A bifurcated movable lower tray contains both an upper buffer reservoir drain and lower buffer reservoir. Both upper and lower buffer reservoirs are provided with hinged covers which act as electrical interlocks to prevent unsafe operation of the apparatus, as well as prevent spillage of buffer solution. The design overcomes safety problems associated with both electrical shock and radioactive chemical contamination. The apparatus is provided with handles for each relocation. Cooling vents are provided for ambient air cooling of the apparatus. A gel mold experiment can be assembled and disassembled with unusual ease with the aid of unique self-locking clamp assemblies.
摘要翻译：公开了一种垂直凝胶板电泳装置，其包括布置在上部和下部缓冲溶液储存器之间的垂直取向的凝胶板。一个分叉的可移动下部托盘包含一个上部缓冲储存器排水和下部缓冲储存器。上部和下部缓冲储存器均设有铰链盖，其作为电气互锁，以防止装置的不安全的操作，以及防止缓冲溶液的溢出。该设计克服了与电击和放射性化学污染相关的安全问题。该设备为每个搬迁提供手柄。提供冷却通风口用于设备的环境空气冷却。借助于独特的自锁夹具组件，凝胶模具实验可以非常容易地组装和拆卸。

6. 发明授权

US6113767A Electrophoresis sequencing apparatus 失效
标题翻译：电泳测序装置
公开(公告)号：US6113767A
公开(公告)日：2000-09-05
申请号：US65901
申请日：1998-04-24
申请人： Robert W. Flesher , Kevin J. Barnes
发明人： Robert W. Flesher , Kevin J. Barnes
IPC分类号： G01N27/447 , G01N27/27 , G01N27/403
CPC分类号： G01N27/44721 , G01N27/44704 , G01N27/44708 , G01N27/44782
摘要： A compact, low cost, automated electrophoresis apparatus provides for the optical detection of multiple DNA samples. A substantially cylindrical gel cartridge houses multiple sample lanes that are sealed on the outer periphery by a shrink tube, which allows for straightforward gel casting, as well as for the pre-casting of sequencing gels. The radial column design of the gel cartridge also facilitates the use of a light source to illuminate one or more sample lanes at the same time. The radial column design further provides for an increased sample lane depth that allows for reading through a greater optical path length of the migrated samples, yielding greater optical signal strength, and an increased signal to noise ratio. The gel lanes can be designed to vary in depth as a function of longitudinal length, allowing for a variable current density. Additionally, this radial design allows for different types of optical detection techniques to be performed on the sample, including transmittance and fluorescence. A system of cooling channels incorporated into the radial column design allows for a coolant to be recirculated in the cooling channels between the actual running sample lanes for better lane-to-lane thermal control. This cooling system allows higher operating voltages and facilitates the use of multiple thermal zones, as required, for instance, for single-strand conformation polymorphism (SSCP) applications.
摘要翻译：一种紧凑，低成本的自动电泳装置提供多个DNA样品的光学检测。基本上圆柱形的凝胶盒容纳多个样品通道，其通过收缩管密封在外周上，这允许直接的凝胶浇铸以及用于预先测定凝胶。凝胶盒的径向柱设计也有助于使用光源同时照亮一个或多个样品通道。径向柱设计进一步提供增加的样品通道深度，其允许读取迁移样品的较大光程长度，产生更大的光信号强度和增加的信噪比。凝胶泳道可以设计成随着纵向长度的变化而变化，允许可变电流密度。另外，这种径向设计允许对样品进行不同类型的光学检测技术，包括透射率和荧光。结合到径向柱设计中的冷却通道的系统允许冷却剂在实际运行的样品通道之间的冷却通道中再循环，以获得更好的车道到车道的热控制。该冷却系统允许更高的工作电压，并且有助于根据需要使用多个热区域，例如单链构象多态性（SSCP）应用。

7. 发明授权

US07066062B2 Torque-setting, tamper-resistant fastener and method and tool for use with same 失效
标题翻译：扭矩设定，防篡改紧固件以及与其一起使用的方法和工具
公开(公告)号：US07066062B2
公开(公告)日：2006-06-27
申请号：US10970274
申请日：2004-10-22
申请人： Robert W. Flesher
发明人： Robert W. Flesher
IPC分类号： B25B23/08 , F16B23/00
CPC分类号： B25B13/485 , F16B23/0023 , F16B23/0046 , F16B23/0069 , F16B31/021 , F16B41/005
摘要： A fastener includes a round, blind hole or pocket in its head. Installation and removal of the fastener is accomplished with a tool containing an eccentric segment on the end of a shaft. When rotated within the pocket, the eccentric segment displaces laterally relative to the shaft to provide a friction grip to the lateral wall of the pocket. The strength of the grip is proportional to the applied torque. Eccentric displacement allows rotation but prevents the tool from spinning out of the fastener thereby eliminating cam-out and surface damage resulting from contact with a spinning tool tip. The eccentric head of the tool can be made disposable and to shear off when a predetermined torque is reached. The smooth-sided round hole offers no purchase for commonly available tools; making the fastener tamper-resistance. In another embodiment, the fastener includes a raised portion in the pocket. A tool having a complementary opening shears off the raised portion at a predetermined torque.
摘要翻译：紧固件在其头部包括圆形，盲孔或口袋。紧固件的安装和拆卸通过在轴的端部上包含偏心段的工具来实现。当在口袋内旋转时，偏心部分相对于轴横向移位，以向口袋的侧壁提供摩擦抓握。把手的强度与施加的扭矩成比例。偏心位移允许旋转，但是防止工具从紧固件中脱出，从而消除了与旋转工具尖端接触造成的凸出和表面损伤。工具的偏心头可以制成一次性的，并且在达到预定扭矩时被剪断。光滑圆孔不提供常用工具的购买; 使紧固件防篡改。在另一个实施例中，紧固件包括在口袋中的凸起部分。具有互补的开口的工具以预定的扭矩剪切掉凸起部分。

8. 发明授权

US5149418A Vertical gel electrophoresis apparatus having universal gel assembly support structure 失效
标题翻译：具有通用凝胶组装支撑结构的立式凝胶电泳装置
公开(公告)号：US5149418A
公开(公告)日：1992-09-22
申请号：US754530
申请日：1991-09-04
申请人： Robert W. Flesher
发明人： Robert W. Flesher
IPC分类号： B01D57/02 , G01N27/447
CPC分类号： B01D57/02 , G01N27/44704
摘要： A vertical gel electrophoresis apparatus featuring a support plate mounted in a buffer solution container, the support plate securing a gel assembly in position and dividing the container into two laterally juxtaposed isolated chambers. The support plate includes two vertical support members which are mounted along opposite vertical sides of the container, and an integral support member mounted along the bottom of the container. A face is cut in each vertical support member to receive opposite vertical edges of a gel assembly. The integral bottom support member includes a face terminating at flanges proximate the vertical support members. The bottom edge of the gel assembly rests on the flanges over the face of the integral bottom support member. The gel assembly is sealed against the integral bottom support member isolating the top opening of the gel assembly from the bottom opening and the gel assembly effectively separates the container into two chambers with the bottom opening being exposed in one electrically charged chamber and the top opening being exposed in the other electrically charged chamber of the opposite polarity.
摘要翻译：一种垂直凝胶电泳装置，其特征在于安装在缓冲溶液容器中的支撑板，支撑板将凝胶组件固定就位并将容器分成两个横向并置的隔离室。支撑板包括沿着容器的相对的垂直侧安装的两个垂直支撑构件，以及沿着容器的底部安装的整体支撑构件。在每个垂直支撑构件中切割面以接收凝胶组件的相对的竖直边缘。整体底部支撑构件包括终止于靠近垂直支撑构件的凸缘处的面。凝胶组件的底部边缘位于整个底部支撑构件的表面上的凸缘上。将凝胶组件密封在一体的底部支撑构件上，该底部支撑构件将凝胶组件的顶部开口与底部开口隔离，并且凝胶组件有效地将容器分离成两个室，底部开口暴露在一个带电室中，顶部开口为暴露在相反极性的另一个充电室中。

9. 发明授权

US4889610A Pop up electrophoresis apparatus and method 失效
标题翻译：弹出电泳仪和方法
公开(公告)号：US4889610A
公开(公告)日：1989-12-26
申请号：US219930
申请日：1988-07-15
申请人： Robert W. Flesher , Mark S. Berninger , Robert W. Blakesley
发明人： Robert W. Flesher , Mark S. Berninger , Robert W. Blakesley
IPC分类号： B01D57/02 , G01N27/447
CPC分类号： G01N27/44704
摘要： An apparatus provides for casting a gel and for presenting the gel for electrophoresis. The apparatus comprises a casting tray and the casting plate which combine to form a mold for the gelable liquid, and an electrophoresis tank in which the electrophoresis process occurs. The floor of the electrophoresis tank rises to form the plate pedestal upon which the casting plate rests during electrophoresis. The floor of the electrophoresis tank forms a cavity at the edges of the plate pedestal in which the casting tray rests during the electrophoresis process. The casting plate is first firmly seated in the bottom of the casting tray forming a mold for the gelable liquid. The gelable liquid is poured into the mold. The comb is placed in the comb slots so as to form wells in the gel. The gelable liquid is allowed to gel, and the comb is removed. The material to undergo electrophoresis is placed in the wells left by the comb. The entire assembly is then placed and aligned on the plate pedestal. The casting tray is then pushed down into the casting tray well. Electrophoresis buffer sufficient to fill the tank to approximately the top of the gel is then poured into the electrophoresis tank. An alternate embodiment is shown.

10. 外观设计

USD303012S Electrophoresis sequencing apparatus tray 失效
公开(公告)号：USD303012S
公开(公告)日：1989-08-22
申请号：US10112
申请日：1987-02-02
申请人： Robert W. Flesher , Kevin T. Barnes , Robert W. Blakesley , Robert W. Lynn
设计人： Robert W. Flesher , Kevin T. Barnes , Robert W. Blakesley , Robert W. Lynn

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