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1. 发明授权

US07500980B2 Method and instrument for effecting anastomosis of respective tissues defining two body lumens 有权
标题翻译：用于影响限定两个体腔的各个组织的吻合的方法和仪器
公开(公告)号：US07500980B2
公开(公告)日：2009-03-10
申请号：US11094606
申请日：2005-03-30
申请人： Robert P. Gill , Christopher J. Hess , William B. Weisenburgh, II , James W. Voegele , Muta M. Issa
发明人： Robert P. Gill , Christopher J. Hess , William B. Weisenburgh, II , James W. Voegele , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B17/0482 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/11 , A61B17/115 , A61B17/1155 , A61B2017/00004 , A61B2017/0412 , A61B2017/0417 , A61B2017/0419 , A61B2017/0427 , A61B2017/06176 , A61B2017/0647 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2017/22069 , A61B2017/2905 , A61B2017/2923
摘要： The instrument disclosed may comprise a tube assembly further comprising substantially coaxially situated and relatively longitudinally movable tubes, supporting and operating an end effector that may be adapted for insertion into and through the urethra, and adapted for use in effecting the anastomosis of a patient's bladder and urethra following a prostatectomy. In alternative embodiments the tube assembly may comprise a rod and two tubes, three tubes, a rod and three tubes, or four tubes. The method disclosed may comprise inserting an instrument having an end effector into the bladder lumen, and using the end effector to urge the bladder wall to the pelvic floor and drive an anchor through the bladder wall and into the pelvic floor.
摘要翻译：所公开的仪器可以包括管组件，其还包括基本上同轴位置并且相对纵向移动的管，其支撑和操作端部执行器，所述末端执行器可以适于插入并穿过尿道，并适于用于实现患者膀胱的吻合，经过前列腺切除术后的尿道。在替代实施例中，管组件可以包括杆和两个管，三个管，杆和三个管，或四个管。所公开的方法可以包括将具有末端执行器的器具插入膀胱腔内，并且使用末端执行器将膀胱壁推动到盆底并驱动锚通过膀胱壁并进入盆底。

2. 发明授权

US07824421B2 Anchors for use in anastomotic procedures 有权
标题翻译：用于吻合手术的锚点
公开(公告)号：US07824421B2
公开(公告)日：2010-11-02
申请号：US11268137
申请日：2005-11-07
申请人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
发明人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/1114 , A61B17/0401 , A61B17/08 , A61B17/10 , A61B17/11 , A61B17/115 , A61B2017/00274 , A61B2017/00367 , A61B2017/0409 , A61B2017/0412 , A61B2017/0437 , A61B2017/047 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2018/00547
摘要： Disclosed is an instrument for use in a procedure to effect anastomosis of a patient's bladder and urethra following a prostatectomy having a tube assembly, and an end effector assembly operably supported by the tube assembly, where the end effector assembly includes an anchor for insertion into and through the patient's bladder wall and pelvic floor and an anchor guide associated therewith.
摘要翻译：公开了一种用于在具有管组件的前列腺切除术之后进行患者膀胱和尿道吻合的手术中的仪器，以及由管组件可操作地支撑的端部执行器组件，其中末端执行器组件包括用于插入和通过患者的膀胱壁和盆底以及与之相关联的锚定导向件。

3. 发明授权

US07708748B2 Anastomosis device 有权
标题翻译：吻合装置
公开(公告)号：US07708748B2
公开(公告)日：2010-05-04
申请号：US11268153
申请日：2005-11-07
申请人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
发明人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/1114 , A61B17/0401 , A61B17/08 , A61B17/10 , A61B17/11 , A61B17/115 , A61B2017/00274 , A61B2017/00367 , A61B2017/0409 , A61B2017/0412 , A61B2017/0437 , A61B2017/047 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2018/00547
摘要： Disclosed is an instrument for use in a procedure to effect anastomosis of a patient's bladder and urethra following a prostatectomy having a tube assembly, and an end effector assembly operably supported by the tube assembly. The end effector assembly includes a positioner assembly and an anchor driver assembly in operable mechanical communication with first and second rods of the tube assembly, so as to be actuable by movement of the first and the second rods with respect to a spine member.
摘要翻译：公开了一种用于在具有管组件的前列腺切除术之后进行患者膀胱和尿道吻合的手术中的仪器，以及由管组件可操作地支撑的端部执行器组件。端部执行器组件包括定位器组件和锚定器驱动器组件，其可与管组件的第一和第二杆可操作地机械连通，以便通过第一和第二杆相对于脊部构件的运动来致动。

4. 发明授权

US07789890B2 Harness and balloon catheter assembly and method for use in anastomosis procedures 有权
标题翻译：线束和球囊导管组装及方法用于吻合手术
公开(公告)号：US07789890B2
公开(公告)日：2010-09-07
申请号：US11268337
申请日：2005-11-07
申请人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
发明人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/1114 , A61B17/0401 , A61B17/08 , A61B17/10 , A61B17/11 , A61B17/115 , A61B2017/00274 , A61B2017/00367 , A61B2017/0409 , A61B2017/0412 , A61B2017/0437 , A61B2017/047 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2018/00547
摘要： Disclosed is an instrument, assembly, and method for use in a procedure to effect anastomosis of a patient's bladder and urethra following a prostatectomy. The instrument comprises a tube assembly having an end effector assembly operably supported thereby, where the end effector assembly includes a harness adapted to receive a balloon portion of a balloon catheter assembly.
摘要翻译：公开了用于在前列腺切除术后进行患者膀胱和尿道吻合的手术中的器械，组装和方法。仪器包括具有可操作地支撑的端部执行器组件的管组件，其中端部执行器组件包括适于容纳球囊导管组件的球囊部分的线束。

5. 发明授权

US07585308B2 Handle system and method for use in anastomotic procedures 有权
标题翻译：手术系统和方法用于吻合手术
公开(公告)号：US07585308B2
公开(公告)日：2009-09-08
申请号：US11268001
申请日：2005-11-07
申请人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
发明人： William B. Weisenburgh, II , Christopher J. Hess , James W. Voegele , Robert P. Gill , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/1114 , A61B17/0401 , A61B17/08 , A61B17/10 , A61B17/11 , A61B17/115 , A61B2017/00274 , A61B2017/00367 , A61B2017/0409 , A61B2017/0412 , A61B2017/0437 , A61B2017/047 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2018/00547
摘要： Disclosed is an instrument and method for use in a procedure to effect anastomosis of a patient's bladder and urethra following a prostatectomy. The instrument comprises a tube assembly, and an end effector assembly operably supported thereby, where the end effector assembly includes a positioner assembly and an anchor driver assembly in operable mechanical communication with a handle, for use in performing anastomotic procedures.
摘要翻译：公开了一种用于在前列腺切除术后进行患者膀胱和尿道吻合的手术中的手段和方法。仪器包括管组件和由其可操作地支撑的端部执行器组件，其中端部执行器组件包括定位器组件和与手柄可操作地机械连通的锚固器驱动器组件，用于执行吻合过程。

6. 发明授权

US07559939B2 Instrument for effecting anastomosis of respective tissues defining two body lumens 有权
标题翻译：用于实现定义两个体腔的各组织吻合的仪器
公开(公告)号：US07559939B2
公开(公告)日：2009-07-14
申请号：US11093694
申请日：2005-03-30
申请人： Robert P. Gill , Christopher J. Hess , William B. Weisenburgh, II , James W. Voegele , Muta M. Issa
发明人： Robert P. Gill , Christopher J. Hess , William B. Weisenburgh, II , James W. Voegele , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B17/0482 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/11 , A61B17/115 , A61B17/1155 , A61B2017/00004 , A61B2017/0412 , A61B2017/0417 , A61B2017/0419 , A61B2017/0427 , A61B2017/06176 , A61B2017/0647 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2017/22069 , A61B2017/2905 , A61B2017/2923
摘要： The instrument disclosed may comprise a tube assembly supporting an end effector that may be adapted for insertion into and through the urethra, and adapted for use in effecting the anastomosis of a patient's bladder and urethra following a prostatectomy. In one embodiment the end effector may comprise a positioner having an extendable and retractable petal operably connected to a tube, an anchor driver, and an anchor releasably held by the anchor driver. In another embodiment the end effector may comprise a positioner and an anchor driver having a driver pin operably connected to a tube.
摘要翻译：所公开的仪器可以包括支撑末端执行器的管组件，其可以适于插入和穿过尿道，并适于用于在前列腺切除术之后实现患者膀胱和尿道的吻合。在一个实施例中，端部执行器可以包括定位器，该定位器具有可操作地连接到管子，锚固器驱动器和由锚固器可释放地保持的锚固件的可伸缩和可缩回的花瓣。在另一个实施例中，末端执行器可以包括定位器和锚定器驱动器，其具有可操作地连接到管的驱动器销。

7. 发明授权

US07713278B2 Method and instrument for effecting anastomosis of respective tissues defining two body lumens 有权
标题翻译：用于影响限定两个体腔的各个组织的吻合的方法和仪器
公开(公告)号：US07713278B2
公开(公告)日：2010-05-11
申请号：US11094585
申请日：2005-03-30
申请人： Christopher J. Hess , Robert P. Gill , William B. Weisenburgh, II , James W. Voegele , Muta M. Issa
发明人： Christopher J. Hess , Robert P. Gill , William B. Weisenburgh, II , James W. Voegele , Muta M. Issa
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B17/0482 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/11 , A61B17/115 , A61B17/1155 , A61B2017/00004 , A61B2017/0412 , A61B2017/0417 , A61B2017/0419 , A61B2017/0427 , A61B2017/06176 , A61B2017/0647 , A61B2017/1103 , A61B2017/1135 , A61B2017/1139 , A61B2017/22069 , A61B2017/2905 , A61B2017/2923
摘要： The method disclosed may be used following a prostatectomy, and may comprise inserting an instrument into the bladder lumen through incisions in the abdomen and bladder wall; using an end effector thereon to urge the bladder wall to the pelvic floor and align the openings of the bladder and urethra, and drive an anchor through the bladder wall into the pelvic floor, thereby connecting a balloon harness to the pelvic floor; inflating a balloon within the harness, which holds the bladder wall surrounding the bladder opening against the pelvic floor; maintaining the balloon in place and draining the bladder via a catheter during the time required for the tissues to effectively knit; and then deflating the balloon, disconnecting the harness, and withdrawing the instrument. The instrument may comprise one or more tubes that support an end effector comprising a positioner, an anchor driver, a harness, a balloon and a catheter.
摘要翻译：所公开的方法可以在前列腺切除术之后使用，并且可以包括通过腹部和膀胱壁中的切口将器械插入膀胱腔内; 使用其上的端部执行器将膀胱壁推动到骨盆底部并对准膀胱和尿道的开口，并且将锚定件穿过膀胱壁驱动到骨盆底部，从而将气囊束连接到盆底; 使线束内的气囊膨胀，其将围绕膀胱开口的膀胱壁抵靠在盆底上; 在组织有效编织所需的时间期间通过导管将气囊保持在适当位置并排出膀胱; 然后放气气球，断开线束并取出仪器。仪器可以包括一个或多个支撑包括定位器，锚定器驱动器，线束，球囊和导管的末端执行器的管。

8. 发明授权

US06338726B1 Treating urinary and other body strictures 失效
标题翻译：治疗尿液和其他身体狭窄
公开(公告)号：US06338726B1
公开(公告)日：2002-01-15
申请号：US08795656
申请日：1997-02-06
申请人： Stuart D. Edwards , Muta M. Issa
发明人： Stuart D. Edwards , Muta M. Issa
IPC分类号： A61M2900
CPC分类号： A61F2/82 , A61B17/00491 , A61B18/14 , A61B18/1485 , A61B18/1492 , A61B2017/005 , A61B2018/0022 , A61B2018/00404 , A61B2018/00553 , A61F2/07 , A61F2/90 , A61F2/94 , A61F2/958 , A61F2002/3008 , A61F2002/5015 , A61F2002/5052 , A61F2250/0098
摘要： The invention provides a method and system for treatment of body strictures to restore luminal diameter to within a normal diameter range, in which the stricture is dilated to stretch its lumen to a desired diameter, collagen is exuded near to existing tissue of the stricture so as to be absorbed by that tissue or adhere to that tissue, making a collagen-enhanced tissue structure, and energy is emitted to affect the collagen-enhanced tissue, such as by ablation or by hardening. Ablation and hardening may be repeated so as to create a set of layers of hardened collagen in the form of a supporting frame, preferably having a hollow cylindrical shape. Dilation of the stricture is achieved by expanding one or more balloons, or by the pressure of exuded collagen, until the stricture is larger than a normal diameter range. When energy is emitted into the collagen, the stricture contracts back to the normal diameter range, either by ablation of excess tissue or by plating of the stricture wall. The stricture's tissue is also isolated by a set of balloons at either or both ends of the stricture, so as to isolate the stricture and restrict the collagen to the stricture's tissue. The stricture's tissue is also supported by a stent, which is preferably tackwelded onto the stricture's tissue using collagen. Collagen adheres to the stent, which supports the stricture's tissue until the stent is absorbed into that tissue.
摘要翻译：本发明提供了一种用于治疗身体狭窄的方法和系统，以将管腔直径恢复到正常直径范围内，其中狭窄被扩张以将其内腔拉伸至期望的直径，胶原蛋白渗透到狭窄的现有组织附近，以便被该组织吸收或粘附到该组织，形成胶原增强的组织结构，并且发射能量以影响胶原增强组织，例如通过消融或硬化。可以重复消融和硬化，以便产生一组支撑框架形式的硬化胶原层，优选具有中空圆柱形状。通过扩张一个或多个气囊或通过渗出的胶原的压力来扩张狭窄，直到狭窄大于正常直径范围为止。当能量发射到胶原中时，通过消融多余的组织或通过电镀狭窄壁，狭窄可缩回到正常直径范围。狭窄的组织也通过一组气囊在狭窄的两端或两端分离，以隔离狭窄并将胶原限制在狭窄的组织上。狭窄的组织也由支架支撑，支架优选使用胶原粘合到狭窄组织上。胶原蛋白粘附到支架上，其支持狭窄的组织，直到支架被吸收到该组织中。

9. 发明授权

US5993445A Resectoscope electrode assembly with simultaneous cutting and coagulation 失效
标题翻译：同时切割和凝结的电镜组合电极
公开(公告)号：US5993445A
公开(公告)日：1999-11-30
申请号：US787779
申请日：1997-01-23
申请人： Muta M. Issa
发明人： Muta M. Issa
IPC分类号： A61B17/00 , A61B18/12 , A61B18/14 , A61B17/39
CPC分类号： A61B18/1206 , A61B18/1485 , A61B18/149 , A61B18/148 , A61B2017/00274 , A61B2018/00547 , A61B2018/00607
摘要： An electrode assembly for a resectoscope includes, a cutting electrode with a loop distal tip and a coagulation electrode with a loop distal tip. A support frame connects the cutting and coagulation electrodes to an energy source which supplies energy from the energy source to the electrodes. The coagulation electrode provides tissue coagulation simultaneously while the cutting electrode cuts tissue. A resectoscope is disclosed which includes the electrode assembly. The resectoscope includes a sheath with a sheath lumen, a working element, and a visualization apparatus.
摘要翻译：一种用于切除镜的电极组件包括具有环形远端的切割电极和具有环形远端的凝固电极。支撑框架将切割和凝固电极连接到从能量源向电极提供能量的能量源。凝固电极在切割电极切割组织时同时提供组织凝固。公开了一种包括电极组件的截面镜。该截面镜包括具有鞘腔的护套，工作元件和可视化装置。

10. 发明授权

US5658280A Resectoscope electrode assembly with simultaneous cutting and coagulation 失效
标题翻译：同时切割和凝结的电镜组合电极
公开(公告)号：US5658280A
公开(公告)日：1997-08-19
申请号：US445597
申请日：1995-05-22
申请人： Muta M. Issa
发明人： Muta M. Issa
IPC分类号： A61B17/00 , A61B18/12 , A61B18/14 , A61B17/39
CPC分类号： A61B18/149 , A61B18/1206 , A61B18/1485 , A61B18/148 , A61B2017/00274 , A61B2018/00547 , A61B2018/00607
摘要： An electrode assembly for a resectoscope includes, a cutting electrode with a loop distal tip and a coagulation electrode with a loop distal tip. A support frame connects the cutting and coagulation electrodes to an energy source which supplies energy from the energy source to the electrodes. The coagulation electrode provides tissue coagulation simultaneously while the cutting electrode cuts tissue. A resectoscope is disclosed which includes the electrode assembly. The resectoscope includes a sheath with a sheath lumen, a working element, and a visualization apparatus.
摘要翻译：一种用于切除镜的电极组件包括具有环形远端的切割电极和具有环形远端的凝固电极。支撑框架将切割和凝固电极连接到从能量源向电极提供能量的能量源。凝固电极在切割电极切割组织时同时提供组织凝固。公开了一种包括电极组件的截面镜。该截面镜包括具有鞘腔的护套，工作元件和可视化装置。

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