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    • 4. 发明申请
    • ULTRASONIC MONITORING DEVICE FOR MEASURING PHYSIOLOGICAL PARAMETERS OF A MAMMAL
    • 用于测量动物生理参数的超声波监测装置
    • US20120197118A1
    • 2012-08-02
    • US13358609
    • 2012-01-26
    • Ronald S. LisieckiTamas Ban
    • Ronald S. LisieckiTamas Ban
    • A61B8/04
    • A61B8/0891A61B5/02141A61B5/6822A61B5/6833A61B8/04A61B8/4236A61B8/4483A61B2560/0412A61B2562/046
    • An ultrasonic monitoring device includes a substrate, a plurality of ultrasonic transducer elements, a computer readable memory medium, a microprocessor, and a power source. The ultrasonic transducer elements are coupled to the substrate. Each ultrasonic transducer element is separately configured to transmit a signal to a target area of a mammal and to receive an echo return signal from the target area. The computer readable memory medium includes program instructions. The microprocessor is coupled to the ultrasonic transducer elements and to the computer readable memory medium for executing the program instructions to determine a physiological parameter of the mammal based on a combined analysis of the echo return signals received by the ultrasonic transducer elements. The power source is coupled to at least one of the ultrasonic transducer elements, the computer readable memory medium, or the microprocessor for supplying electrical energy.
    • 超声波监测装置包括基板,多个超声波换能器元件,计算机可读存储介质,微处理器和电源。 超声换能器元件耦合到基底。 每个超声波换能器元件分别被配置成将信号发送到哺乳动物的目标区域并且从目标区域接收回波返回信号。 计算机可读存储介质包括程序指令。 微处理器耦合到超声波换能器元件和计算机可读存储介质,用于执行程序指令以基于由超声换能器元件接收的回波返回信号的组合分析来确定哺乳动物的生理参数。 电源耦合到超声波换能器元件,计算机可读存储介质或用于提供电能的微处理器中的至少一个。
    • 6. 发明授权
    • Mapping retinal function using corneal electrode array
    • 使用角膜电极阵列绘制视网膜功能
    • US07384145B2
    • 2008-06-10
    • US11707783
    • 2007-02-15
    • John R. HetlingTamas BanSafa Rahmani
    • John R. HetlingTamas BanSafa Rahmani
    • A61B3/00A61B3/10
    • A61B5/0496
    • A system and method for obtaining information about the spatial distribution of photoreceptor activity and neural activity in the retina using simultaneously recorded multiple biopotential signals. The information thus gathered is used to assess retinal dysfunction due to trauma or disease. The biopotential signals are recorded from the surface of the eye and head using a plurality of electrodes, including those integral to a contact lens. The biopotential signals are recorded before, during and after the presentation of an optical stimulus to the subject eye. The recorded biopotential signals are then analyzed and interpreted to reveal the distribution of photoreceptor activity and neural activity across the retina. The analysis and interpretation of the biopotential signals is quantitative, and makes use of an electromagnetic model of the subject eye. The subject may be animal or human.
    • 使用同时记录的多个生物电位信号获得关于视网膜中的感光器活性和神经活动的空间分布的信息的系统和方法。 所收集的信息用于评估由于创伤或疾病引起的视网膜功能障碍。 使用多个电极(包括与隐形眼镜一体的电极)从眼睛和头部的表面记录生物电位信号。 生物电位信号在向受试者眼睛呈现光学刺激之前,期间和之后记录。 然后对记录的生物电位信号进行分析和解释,以揭示视网膜上感光器活性和神经活动的分布。 生物电位信号的分析和解释是定量的,并利用了目标眼的电磁模型。 受试者可能是动物或人类。
    • 7. 发明申请
    • Mapping retinal function using corneal electrode array
    • 使用角膜电极阵列绘制视网膜功能
    • US20070188710A1
    • 2007-08-16
    • US11707783
    • 2007-02-15
    • John HetlingTamas BanSafa Rahmani
    • John HetlingTamas BanSafa Rahmani
    • A61B3/10
    • A61B5/0496
    • A system and method for obtaining information about the spatial distribution of photoreceptor activity and neural activity in the retina using simultaneously recorded multiple biopotential signals. The information thus gathered is used to assess retinal dysfunction due to trauma or disease. The biopotential signals are recorded from the surface of the eye and head using a plurality of electrodes, including those integral to a contact lens. The biopotential signals are recorded before, during and after the presentation of an optical stimulus to the subject eye. The recorded biopotential signals are then analyzed and interpreted to reveal the distribution of photoreceptor activity and neural activity across the retina. The analysis and interpretation of the biopotential signals is quantitative, and makes use of an electromagnetic model of the subject eye. The subject may be animal or human.
    • 使用同时记录的多个生物电位信号获得关于视网膜中的感光器活性和神经活动的空间分布的信息的系统和方法。 所收集的信息用于评估由于创伤或疾病引起的视网膜功能障碍。 使用多个电极(包括与隐形眼镜整体的电极)从眼睛和头部的表面记录生物电位信号。 生物电位信号在向受试者眼睛呈现光学刺激之前,期间和之后记录。 然后对记录的生物电位信号进行分析和解释,以揭示视网膜上感光器活性和神经活动的分布。 生物电位信号的分析和解释是定量的,并利用了目标眼的电磁模型。 受试者可能是动物或人类。
    • 8. 发明授权
    • Ultrasonic monitoring device for measuring physiological parameters of a mammal
    • 用于测量哺乳动物的生理参数的超声波监测装置
    • US08864670B2
    • 2014-10-21
    • US13358609
    • 2012-01-26
    • Ronald S. LisieckiTamas Ban
    • Ronald S. LisieckiTamas Ban
    • A61B8/00A61B5/00A61B8/08A61B8/04A61B5/021
    • A61B8/0891A61B5/02141A61B5/6822A61B5/6833A61B8/04A61B8/4236A61B8/4483A61B2560/0412A61B2562/046
    • An ultrasonic monitoring device includes a substrate, a plurality of ultrasonic transducer elements, a computer readable memory medium, a microprocessor, and a power source. The ultrasonic transducer elements are coupled to the substrate. Each ultrasonic transducer element is separately configured to transmit a signal to a target area of a mammal and to receive an echo return signal from the target area. The computer readable memory medium includes program instructions. The microprocessor is coupled to the ultrasonic transducer elements and to the computer readable memory medium for executing the program instructions to determine a physiological parameter of the mammal based on a combined analysis of the echo return signals received by the ultrasonic transducer elements. The power source is coupled to at least one of the ultrasonic transducer elements, the computer readable memory medium, or the microprocessor for supplying electrical energy.
    • 超声波监测装置包括基板,多个超声波换能器元件,计算机可读存储介质,微处理器和电源。 超声换能器元件耦合到基底。 每个超声波换能器元件分别配置成将信号传送到哺乳动物的目标区域并从目标区域接收回波返回信号。 计算机可读存储介质包括程序指令。 微处理器耦合到超声波换能器元件和计算机可读存储介质,用于执行程序指令以基于由超声换能器元件接收的回波返回信号的组合分析来确定哺乳动物的生理参数。 电源耦合到超声波换能器元件,计算机可读存储介质或用于提供电能的微处理器中的至少一个。
    • 9. 发明授权
    • Apparatus and methods for mapping retinal function
    • 视网膜功能的设备和方法
    • US08118752B2
    • 2012-02-21
    • US12157276
    • 2008-06-09
    • John R. HetlingTamas BanSafa Rahmani
    • John R. HetlingTamas BanSafa Rahmani
    • A61B13/00A61B5/04
    • A61B5/0496
    • The present invention provides an electrode array device for simultaneously detecting electrical potentials at five or more locations on the anterior surface of an eye. The device comprises a dielectric lens substrate having a concave inner surface conforming to the anterior surface of the eye, and at least five recording electrodes positioned in relation to the inner surface of the lens substrate so as to make electrical connection with the anterior surface of the eye when the lens substrate is placed on the anterior surface of eye. Each recording electrode is in electrically conductive communication with a corresponding conductive contact, there being one conductive contact for each recording electrode. Each conductive contact is adapted for operable connection to signal processor, and each conductive contact is electrically insulated from the anterior surface of the eye. A computational method for analyzing electrophysiological potentials recorded at five or more locations on the anterior surface of the eye, which reflect the spatial distribution of activity of the retina, is also provided.
    • 本发明提供一种用于同时检测眼睛前表面上五个或更多个位置处的电位的电极阵列装置。 该装置包括具有与眼睛前表面相符的凹内表面的介电透镜基底和相对于透镜基底的内表面定位的至少五个记录电极,以便与透镜基片的前表面电连接 当镜片基底放置在眼睛的前表面上时,眼睛。 每个记录电极与对应的导电接触导电连通,每个记录电极具有一个导电接触。 每个导电触点适于可操作地连接到信号处理器,并且每个导电触点与眼睛的前表面电绝缘。 还提供了一种用于分析记录在眼睛前表面上的五个或更多个位置处的电生理电位的计算方法,其反映了视网膜的活动的空间分布。
    • 10. 发明申请
    • Apparatus and methods for mapping retinal function
    • 视网膜功能的设备和方法
    • US20080294066A1
    • 2008-11-27
    • US12157276
    • 2008-06-09
    • John R. HetlingTamas BanSafa Rahmani
    • John R. HetlingTamas BanSafa Rahmani
    • A61B5/05
    • A61B5/0496
    • The present invention provides an electrode array device for simultaneously detecting electrical potentials at five or more locations on the anterior surface of an eye. The device comprises a dielectric lens substrate having a concave inner surface conforming to the anterior surface of the eye, and at least five recording electrodes positioned in relation to the inner surface of the lens substrate so as to make electrical connection with the anterior surface of the eye when the lens substrate is placed on the anterior surface of eye. Each recording electrode is in electrically conductive communication with a corresponding conductive contact, there being one conductive contact for each recording electrode. Each conductive contact is adapted for operable connection to signal processor, and each conductive contact is electrically insulated from the anterior surface of the eye. A computational method for analyzing electrophysiological potentials recorded at five or more locations on the anterior surface of the eye, which reflect the spatial distribution of activity of the retina, is also provided.
    • 本发明提供一种用于同时检测眼睛前表面上五个或更多个位置处的电位的电极阵列装置。 该装置包括具有与眼睛前表面相符的凹内表面的介电透镜基底和相对于透镜基底的内表面定位的至少五个记录电极,以便与透镜基片的前表面电连接 当镜片基底放置在眼睛的前表面上时,眼睛。 每个记录电极与对应的导电接触导电连通,每个记录电极具有一个导电接触。 每个导电触点适于可操作地连接到信号处理器,并且每个导电触点与眼睛的前表面电绝缘。 还提供了一种用于分析记录在眼睛前表面上的五个或更多个位置处的电生理电位的计算方法,其反映了视网膜的活动的空间分布。