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1. 发明授权

US07384145B2 Mapping retinal function using corneal electrode array 有权
标题翻译：使用角膜电极阵列绘制视网膜功能
公开(公告)号：US07384145B2
公开(公告)日：2008-06-10
申请号：US11707783
申请日：2007-02-15
申请人： John R. Hetling , Tamas Ban , Safa Rahmani
发明人： John R. Hetling , Tamas Ban , Safa Rahmani
IPC分类号： A61B3/00 , A61B3/10
CPC分类号： A61B5/0496
摘要： A system and method for obtaining information about the spatial distribution of photoreceptor activity and neural activity in the retina using simultaneously recorded multiple biopotential signals. The information thus gathered is used to assess retinal dysfunction due to trauma or disease. The biopotential signals are recorded from the surface of the eye and head using a plurality of electrodes, including those integral to a contact lens. The biopotential signals are recorded before, during and after the presentation of an optical stimulus to the subject eye. The recorded biopotential signals are then analyzed and interpreted to reveal the distribution of photoreceptor activity and neural activity across the retina. The analysis and interpretation of the biopotential signals is quantitative, and makes use of an electromagnetic model of the subject eye. The subject may be animal or human.
摘要翻译：使用同时记录的多个生物电位信号获得关于视网膜中的感光器活性和神经活动的空间分布的信息的系统和方法。所收集的信息用于评估由于创伤或疾病引起的视网膜功能障碍。使用多个电极（包括与隐形眼镜一体的电极）从眼睛和头部的表面记录生物电位信号。生物电位信号在向受试者眼睛呈现光学刺激之前，期间和之后记录。然后对记录的生物电位信号进行分析和解释，以揭示视网膜上感光器活性和神经活动的分布。生物电位信号的分析和解释是定量的，并利用了目标眼的电磁模型。受试者可能是动物或人类。

2. 发明授权

US08118752B2 Apparatus and methods for mapping retinal function 有权
标题翻译：视网膜功能的设备和方法
公开(公告)号：US08118752B2
公开(公告)日：2012-02-21
申请号：US12157276
申请日：2008-06-09
申请人： John R. Hetling , Tamas Ban , Safa Rahmani
发明人： John R. Hetling , Tamas Ban , Safa Rahmani
IPC分类号： A61B13/00 , A61B5/04
CPC分类号： A61B5/0496
摘要： The present invention provides an electrode array device for simultaneously detecting electrical potentials at five or more locations on the anterior surface of an eye. The device comprises a dielectric lens substrate having a concave inner surface conforming to the anterior surface of the eye, and at least five recording electrodes positioned in relation to the inner surface of the lens substrate so as to make electrical connection with the anterior surface of the eye when the lens substrate is placed on the anterior surface of eye. Each recording electrode is in electrically conductive communication with a corresponding conductive contact, there being one conductive contact for each recording electrode. Each conductive contact is adapted for operable connection to signal processor, and each conductive contact is electrically insulated from the anterior surface of the eye. A computational method for analyzing electrophysiological potentials recorded at five or more locations on the anterior surface of the eye, which reflect the spatial distribution of activity of the retina, is also provided.
摘要翻译：本发明提供一种用于同时检测眼睛前表面上五个或更多个位置处的电位的电极阵列装置。该装置包括具有与眼睛前表面相符的凹内表面的介电透镜基底和相对于透镜基底的内表面定位的至少五个记录电极，以便与透镜基片的前表面电连接当镜片基底放置在眼睛的前表面上时，眼睛。每个记录电极与对应的导电接触导电连通，每个记录电极具有一个导电接触。每个导电触点适于可操作地连接到信号处理器，并且每个导电触点与眼睛的前表面电绝缘。还提供了一种用于分析记录在眼睛前表面上的五个或更多个位置处的电生理电位的计算方法，其反映了视网膜的活动的空间分布。

3. 发明申请

US20080294066A1 Apparatus and methods for mapping retinal function 有权
标题翻译：视网膜功能的设备和方法
公开(公告)号：US20080294066A1
公开(公告)日：2008-11-27
申请号：US12157276
申请日：2008-06-09
申请人： John R. Hetling , Tamas Ban , Safa Rahmani
发明人： John R. Hetling , Tamas Ban , Safa Rahmani
IPC分类号： A61B5/05
CPC分类号： A61B5/0496
摘要： The present invention provides an electrode array device for simultaneously detecting electrical potentials at five or more locations on the anterior surface of an eye. The device comprises a dielectric lens substrate having a concave inner surface conforming to the anterior surface of the eye, and at least five recording electrodes positioned in relation to the inner surface of the lens substrate so as to make electrical connection with the anterior surface of the eye when the lens substrate is placed on the anterior surface of eye. Each recording electrode is in electrically conductive communication with a corresponding conductive contact, there being one conductive contact for each recording electrode. Each conductive contact is adapted for operable connection to signal processor, and each conductive contact is electrically insulated from the anterior surface of the eye. A computational method for analyzing electrophysiological potentials recorded at five or more locations on the anterior surface of the eye, which reflect the spatial distribution of activity of the retina, is also provided.
摘要翻译：本发明提供一种用于同时检测眼睛前表面上五个或更多个位置处的电位的电极阵列装置。该装置包括具有与眼睛前表面相符的凹内表面的介电透镜基底和相对于透镜基底的内表面定位的至少五个记录电极，以便与透镜基片的前表面电连接当镜片基底放置在眼睛的前表面上时，眼睛。每个记录电极与对应的导电接触导电连通，每个记录电极具有一个导电接触。每个导电触点适于可操作地连接到信号处理器，并且每个导电触点与眼睛的前表面电绝缘。还提供了一种用于分析记录在眼睛前表面上的五个或更多个位置处的电生理电位的计算方法，其反映了视网膜的活动的空间分布。

4. 发明申请

US20070188710A1 Mapping retinal function using corneal electrode array 有权
标题翻译：使用角膜电极阵列绘制视网膜功能
公开(公告)号：US20070188710A1
公开(公告)日：2007-08-16
申请号：US11707783
申请日：2007-02-15
申请人： John Hetling , Tamas Ban , Safa Rahmani
发明人： John Hetling , Tamas Ban , Safa Rahmani
IPC分类号： A61B3/10
CPC分类号： A61B5/0496
摘要： A system and method for obtaining information about the spatial distribution of photoreceptor activity and neural activity in the retina using simultaneously recorded multiple biopotential signals. The information thus gathered is used to assess retinal dysfunction due to trauma or disease. The biopotential signals are recorded from the surface of the eye and head using a plurality of electrodes, including those integral to a contact lens. The biopotential signals are recorded before, during and after the presentation of an optical stimulus to the subject eye. The recorded biopotential signals are then analyzed and interpreted to reveal the distribution of photoreceptor activity and neural activity across the retina. The analysis and interpretation of the biopotential signals is quantitative, and makes use of an electromagnetic model of the subject eye. The subject may be animal or human.
摘要翻译：使用同时记录的多个生物电位信号获得关于视网膜中的感光器活性和神经活动的空间分布的信息的系统和方法。所收集的信息用于评估由于创伤或疾病引起的视网膜功能障碍。使用多个电极（包括与隐形眼镜整体的电极）从眼睛和头部的表面记录生物电位信号。生物电位信号在向受试者眼睛呈现光学刺激之前，期间和之后记录。然后对记录的生物电位信号进行分析和解释，以揭示视网膜上感光器活性和神经活动的分布。生物电位信号的分析和解释是定量的，并利用了目标眼的电磁模型。受试者可能是动物或人类。

5. 发明申请

US20140121639A1 FLUID FLOW PASSAGE TO IMPROVE AIR-IN-LINE DETECTION 有权
标题翻译：流体流通以改善空中在线检测
公开(公告)号：US20140121639A1
公开(公告)日：2014-05-01
申请号：US14065938
申请日：2013-10-29
申请人： Michael G. Lowery , Tamas Ban , Anatoly S. Belkin , Paul T. Kotnik
发明人： Michael G. Lowery , Tamas Ban , Anatoly S. Belkin , Paul T. Kotnik
IPC分类号： A61M5/36 , A61M5/168 , A61M5/142 , A61M5/172
CPC分类号： A61M5/365 , A61M2205/3375
摘要： Infusion systems and methods containing unique inner passage configurations are provided to improve the in-line detection of air in a fluid delivery line of an infusion system by reducing the problems associated with the presence of bouncing air bubbles and stuck fluid droplets in the fluid delivery line.
摘要翻译：提供了包含独特内部通道构造的输液系统和方法，以通过减少与弹性气泡的存在和粘附的液滴在流体输送管线中的相关问题来改善在输注系统的流体输送管线中的空气的在线检测。

6. 发明申请

US20120197118A1 ULTRASONIC MONITORING DEVICE FOR MEASURING PHYSIOLOGICAL PARAMETERS OF A MAMMAL 有权
标题翻译：用于测量动物生理参数的超声波监测装置
公开(公告)号：US20120197118A1
公开(公告)日：2012-08-02
申请号：US13358609
申请日：2012-01-26
申请人： Ronald S. Lisiecki , Tamas Ban
发明人： Ronald S. Lisiecki , Tamas Ban
IPC分类号： A61B8/04
CPC分类号： A61B8/0891 , A61B5/02141 , A61B5/6822 , A61B5/6833 , A61B8/04 , A61B8/4236 , A61B8/4483 , A61B2560/0412 , A61B2562/046
摘要： An ultrasonic monitoring device includes a substrate, a plurality of ultrasonic transducer elements, a computer readable memory medium, a microprocessor, and a power source. The ultrasonic transducer elements are coupled to the substrate. Each ultrasonic transducer element is separately configured to transmit a signal to a target area of a mammal and to receive an echo return signal from the target area. The computer readable memory medium includes program instructions. The microprocessor is coupled to the ultrasonic transducer elements and to the computer readable memory medium for executing the program instructions to determine a physiological parameter of the mammal based on a combined analysis of the echo return signals received by the ultrasonic transducer elements. The power source is coupled to at least one of the ultrasonic transducer elements, the computer readable memory medium, or the microprocessor for supplying electrical energy.
摘要翻译：超声波监测装置包括基板，多个超声波换能器元件，计算机可读存储介质，微处理器和电源。超声换能器元件耦合到基底。每个超声波换能器元件分别被配置成将信号发送到哺乳动物的目标区域并且从目标区域接收回波返回信号。计算机可读存储介质包括程序指令。微处理器耦合到超声波换能器元件和计算机可读存储介质，用于执行程序指令以基于由超声换能器元件接收的回波返回信号的组合分析来确定哺乳动物的生理参数。电源耦合到超声波换能器元件，计算机可读存储介质或用于提供电能的微处理器中的至少一个。

7. 发明授权

US08801656B2 Fluid flow passage to improve air-in-line detection 有权
标题翻译：流体通道，以改善在线检测
公开(公告)号：US08801656B2
公开(公告)日：2014-08-12
申请号：US14065938
申请日：2013-10-29
申请人： Michael G. Lowery , Tamas Ban , Anatoly S. Belkin , Paul T. Kotnik
发明人： Michael G. Lowery , Tamas Ban , Anatoly S. Belkin , Paul T. Kotnik
IPC分类号： A61M31/00 , A61M5/168 , A61M5/142 , A61M5/36 , A61M5/172
CPC分类号： A61M5/365 , A61M2205/3375
摘要： Infusion systems and methods containing unique inner passage configurations are provided to improve the in-line detection of air in a fluid delivery line of an infusion system by reducing the problems associated with the presence of bouncing air bubbles and stuck fluid droplets in the fluid delivery line.
摘要翻译：提供了包含独特内部通道构造的输液系统和方法，以通过减少与弹性气泡的存在和粘附的液滴在流体输送管线中的相关问题来改善输注系统的流体输送管线中的空气的在线检测。

8. 发明申请

US20130047113A1 Systems and Methods for a Graphical Interface including a Graphical Representation of Medical Data 有权
标题翻译：包括医学数据图形表示的图形界面的系统和方法
公开(公告)号：US20130047113A1
公开(公告)日：2013-02-21
申请号：US13588026
申请日：2012-08-17
申请人： Robert Mayer , Devy Amy Lee , Gabriele Ott , Candida Arvelo , Timothy L. Ruchti , Tamas Ban , Mohammad M. Khair , Nancy H. Hedlund , Robert M. Hume
发明人： James A. Hume , Robert Mayer , Devy Amy Lee , Gabriele Ott , Candida Arvelo , Timothy L. Ruchti , Tamas Ban , Mohammad M. Khair , Nancy H. Hedlund
IPC分类号： G06F3/048
CPC分类号： G06Q10/10 , A61M2205/502 , A61M2205/52 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H10/60 , G16H15/00 , G16H40/63 , G16H50/20 , G16H50/70
摘要： This disclosure describes systems and methods for a graphical interface including a graphical representation of medical data. The graphical interface platform may receive medical data and provide medical safety reporting capabilities including reporting of history data and real-time visual monitoring data. The graphical interface platform may be configured to identify potential problems and corrections to medical devices in operation while a reporting cycle is underway through visual representation of performance metrics.
摘要翻译：本公开描述了用于包括医学数据的图形表示的图形界面的系统和方法。图形界面平台可以接收医疗数据并提供医疗安全报告功能，包括历史数据的报告和实时的可视化监视数据。图形界面平台可以被配置为在通过可视表示性能度量进行报告周期的同时，识别在操作中的医疗设备的潜在问题和修正。

9. 发明授权

US09240002B2 Systems and methods for a graphical interface including a graphical representation of medical data 有权
标题翻译：图形界面的系统和方法，包括医疗数据的图形表示
公开(公告)号：US09240002B2
公开(公告)日：2016-01-19
申请号：US13588026
申请日：2012-08-17
申请人： James A. Hume , Robert M. Hume , Robert Mayer , Devy Amy Lee , Gabriele Ott , Candida Arvelo , Timothy L. Ruchti , Tamas Ban , Mohammad M. Khair , Nancy H. Hedlund
发明人： James A. Hume , Robert Mayer , Devy Amy Lee , Gabriele Ott , Candida Arvelo , Timothy L. Ruchti , Tamas Ban , Mohammad M. Khair , Nancy H. Hedlund
IPC分类号： G06F3/048 , G06Q10/10 , G06Q50/22 , G06F19/00
CPC分类号： G06Q10/10 , A61M2205/502 , A61M2205/52 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H10/60 , G16H15/00 , G16H40/63 , G16H50/20 , G16H50/70
摘要： This disclosure describes systems and methods for a graphical interface including a graphical representation of medical data. The graphical interface platform may receive medical data and provide medical safety reporting capabilities including reporting of history data and real-time visual monitoring data. The graphical interface platform may be configured to identify potential problems and corrections to medical devices in operation while a reporting cycle is underway through visual representation of performance metrics.
摘要翻译：本公开描述了用于包括医学数据的图形表示的图形界面的系统和方法。图形界面平台可以接收医疗数据并提供医疗安全报告功能，包括历史数据的报告和实时的可视化监视数据。图形界面平台可以被配置为在通过可视表示性能度量进行报告周期的同时，识别在操作中的医疗设备的潜在问题和修正。

10. 发明授权

US08864670B2 Ultrasonic monitoring device for measuring physiological parameters of a mammal 有权
标题翻译：用于测量哺乳动物的生理参数的超声波监测装置
公开(公告)号：US08864670B2
公开(公告)日：2014-10-21
申请号：US13358609
申请日：2012-01-26
申请人： Ronald S. Lisiecki , Tamas Ban
发明人： Ronald S. Lisiecki , Tamas Ban
IPC分类号： A61B8/00 , A61B5/00 , A61B8/08 , A61B8/04 , A61B5/021
CPC分类号： A61B8/0891 , A61B5/02141 , A61B5/6822 , A61B5/6833 , A61B8/04 , A61B8/4236 , A61B8/4483 , A61B2560/0412 , A61B2562/046
摘要： An ultrasonic monitoring device includes a substrate, a plurality of ultrasonic transducer elements, a computer readable memory medium, a microprocessor, and a power source. The ultrasonic transducer elements are coupled to the substrate. Each ultrasonic transducer element is separately configured to transmit a signal to a target area of a mammal and to receive an echo return signal from the target area. The computer readable memory medium includes program instructions. The microprocessor is coupled to the ultrasonic transducer elements and to the computer readable memory medium for executing the program instructions to determine a physiological parameter of the mammal based on a combined analysis of the echo return signals received by the ultrasonic transducer elements. The power source is coupled to at least one of the ultrasonic transducer elements, the computer readable memory medium, or the microprocessor for supplying electrical energy.
摘要翻译：超声波监测装置包括基板，多个超声波换能器元件，计算机可读存储介质，微处理器和电源。超声换能器元件耦合到基底。每个超声波换能器元件分别配置成将信号传送到哺乳动物的目标区域并从目标区域接收回波返回信号。计算机可读存储介质包括程序指令。微处理器耦合到超声波换能器元件和计算机可读存储介质，用于执行程序指令以基于由超声换能器元件接收的回波返回信号的组合分析来确定哺乳动物的生理参数。电源耦合到超声波换能器元件，计算机可读存储介质或用于提供电能的微处理器中的至少一个。

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