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1. 发明授权

US06448258B2 Treating fibromyalgia and chronic fatigue syndrome 失效
标题翻译：治疗纤维肌痛和慢性疲劳综合征
公开(公告)号：US06448258B2
公开(公告)日：2002-09-10
申请号：US09836660
申请日：2001-04-17
申请人： Robert B. McCall , Robert Clyde Marshall , David W. Robertson , Thomas M. Ashley
发明人： Robert B. McCall , Robert Clyde Marshall , David W. Robertson , Thomas M. Ashley
IPC分类号： A61K314745
CPC分类号： A61K31/445 , A61K31/451 , A61K31/4745 , A61K31/48
摘要： The present invention provides for methods for the treatment of fibromyalgia syndrome or chronic fatigue syndrome by the administration of heterocyclic amine-type compounds or a salt of any said compound.
摘要翻译：本发明提供了通过施用杂环胺型化合物或任何所述化合物的盐来治疗纤维肌痛综合征或慢性疲劳综合征的方法。

2. 发明授权

US06555548B2 Compounds for treating fibromyalgia and chronic fatigue syndrome 失效
标题翻译：用于治疗纤维肌痛和慢性疲劳综合征的化合物
公开(公告)号：US06555548B2
公开(公告)日：2003-04-29
申请号：US10159913
申请日：2002-05-30
申请人： Robert B. McCall , Robert Clyde Marshall , David W. Robertson , Thomas M. Ashley
发明人： Robert B. McCall , Robert Clyde Marshall , David W. Robertson , Thomas M. Ashley
IPC分类号： A61K31437
CPC分类号： A61K31/445 , A61K31/451 , A61K31/4745 , A61K31/48
摘要： The present invention provides for methods for the treatment of fibromyalgia syndrome or chronic fatigue syndrome by the administration of cabergoline-type compounds or a salt of said compound.
摘要翻译：本发明提供了通过给予卡麦角林型化合物或所述化合物的盐来治疗纤维肌痛综合征或慢性疲劳综合征的方法。

3. 发明授权

US08834357B2 Steering mechanism 有权
标题翻译：转向机制
公开(公告)号：US08834357B2
公开(公告)日：2014-09-16
申请号：US12612961
申请日：2009-11-05
申请人： Christopher Oskin , Isaac Ostrovsky , David W. Robertson , Michael Barenboym
发明人： Christopher Oskin , Isaac Ostrovsky , David W. Robertson , Michael Barenboym
IPC分类号： A61B1/00 , A61B1/005 , A61M25/01
CPC分类号： A61B1/0051 , A61B1/008 , A61M25/0136 , A61M2205/10
摘要： A steering mechanism is used as part of a medical device such as a catheter or an endoscope to allow movement of a steerable distal portion of the catheter or endoscope. The mechanism can include a elongate housing adapted to be coupled to the steerable portion of the medical device and an actuation system including an actuator, a first cam, and a second cam. The actuator can move the first cam between a first position and a second position along a first axis (or about a second axis different than the first axis) to move the steerable portion of the medical device along a first plane. The actuator can move the second cam between a first position and a second position along the second axis (or about the first axis) to move the steerable portion of the medical device along a second plane different than the first plane.
摘要翻译：转向机构用作诸如导管或内窥镜的医疗装置的一部分，以允许导管或内窥镜的可转向远端部分的移动。机构可以包括适于联接到医疗装置的可操纵部分的细长壳体和包括致动器，第一凸轮和第二凸轮的致动系统。致动器可以沿着第一轴线（或者围绕不同于第一轴线的第二轴线）在第一位置和第二位置之间移动第一凸轮，以沿着第一平面移动医疗装置的可操纵部分。致动器可以沿着第二轴线（或围绕第一轴线）在第一位置和第二位置之间移动第二凸轮，以沿着与第一平面不同的第二平面移动医疗装置的可转向部分。

4. 发明申请

US20110306988A1 DUAL OFFSET ARC NEEDLE FOR ANCHOR PLACEMENT OF A MALE INCONTINENCE SLING 有权
标题翻译：用于锚固放置男性不连续的双重偏移弧针
公开(公告)号：US20110306988A1
公开(公告)日：2011-12-15
申请号：US13074895
申请日：2011-03-29
申请人： David W. Robertson , Michael F. Weiser , Kevin L. Newell , John Petricca
发明人： David W. Robertson , Michael F. Weiser , Kevin L. Newell , John Petricca
IPC分类号： A61B17/10
CPC分类号： A61B17/06109 , A61B2017/00805 , A61B2017/0608 , A61B2017/061
摘要： In some embodiments, an apparatus includes a handle and an elongate member coupled to the handle. The elongate member has a first portion, a second portion and a third portion. The first portion of the elongate member extends from the handle and defines a first longitudinal axis. The second portion of the elongate member extends from the first portion and defines a second longitudinal axis. The first longitudinal axis and the second longitudinal axis define a first angle and a first plane. The third portion of the elongate member extends from the second portion of the elongate member and defines a third longitudinal axis. The third longitudinal axis and the second longitudinal axis define a second angle and a second plane. The second plane is non-parallel with the first plane.
摘要翻译：在一些实施例中，装置包括手柄和联接到手柄的细长构件。细长构件具有第一部分，第二部分和第三部分。细长构件的第一部分从手柄延伸并且限定第一纵向轴线。细长构件的第二部分从第一部分延伸并且限定第二纵向轴线。第一纵向轴线和第二纵向轴线限定第一角度和第一平面。细长构件的第三部分从细长构件的第二部分延伸并限定第三纵向轴线。第三纵向轴线和第二纵向轴线限定第二角度和第二平面。第二平面与第一平面不平行。

5. 发明申请

US20110028987A1 Medical retrieval device with frangible basket 失效
标题翻译：带易碎篮的医疗检索装置
公开(公告)号：US20110028987A1
公开(公告)日：2011-02-03
申请号：US12656283
申请日：2010-01-22
申请人： William R. Little , Jason W. Kear , David W. Robertson , James Teague , James W. Riley
发明人： William R. Little , Jason W. Kear , David W. Robertson , James Teague , James W. Riley
IPC分类号： A61B17/221
CPC分类号： A61B17/221 , A61B90/03 , A61B2017/00876 , A61B2017/2212 , A61B2017/2215 , A61B2090/037
摘要： The invention relates to a medical retrieval device with a basket that has at least one leg that is frangible (i.e., easily breakable) and/or able to dissociate from at least one other leg upon the application of a predetermined force to the basket. The invention allows an operator to release captured material (e.g., a stone) from the basket when the device is still inserted in the body. In an embodiment, the basket legs associate by a magnetic interaction that can be overcome by applying a predetermined force to the basket. In another embodiment, at least a portion of at least one basket leg is made from, or coated with, a substance that is adhesive or that joins at least two legs together when the substance is solid but which melts, dissolves or weakens upon the application of an electrical, thermal or chemical change. In yet another embodiment, the invention provides a basket with at least two legs that are joined together by a joining member that can break, or from which one or more legs can dissociate, upon the application of a predetermined force. In yet another embodiment, the invention provides a basket with at least two legs that are joined together by a joining member by means of at least one shear pin that can break upon the application of a predetermined force.
摘要翻译：本发明涉及一种具有篮子的医疗检索装置，该篮子具有至少一条腿，所述至少一条腿在将预定的力施加到篮子上时，其易碎（或易于破裂）和/或能够与至少一个其他腿分离。本发明允许操作者当装置仍然插入身体时从篮子释放捕获的材料（例如石头）。在一个实施例中，篮子腿通过磁性相互作用相关联，该相互作用可以通过对篮子施加预定的力来克服。在另一个实施例中，至少一个篮腿的至少一部分由物质制成或涂覆有物质，当该物质是固体但在施用时熔化，溶解或弱化的物质是粘合剂或将至少两条腿连接在一起的物质的电，热或化学变化。在另一个实施例中，本发明提供了一种具有至少两个腿部的篮子，所述至少两个腿部通过接合构件连接在一起，所述连接构件在施加预定的力时可能会断裂，或者由一个或多个腿部分离。在另一个实施例中，本发明提供了一种具有至少两个腿部的篮，其通过连接构件通过至少一个剪切销连接在一起，所述剪切销在施加预定力时可能破裂。

6. 发明授权

US07678119B2 Medical retrieval device with frangible basket 失效
标题翻译：带易碎篮的医疗检索装置
公开(公告)号：US07678119B2
公开(公告)日：2010-03-16
申请号：US10342785
申请日：2003-01-15
申请人： William R. Little , Jason W. Kear , David W. Robertson , James Teague , James W. Riley
发明人： William R. Little , Jason W. Kear , David W. Robertson , James Teague , James W. Riley
IPC分类号： A61B17/22 , A61B17/24 , A61M29/00
CPC分类号： A61B17/221 , A61B90/03 , A61B2017/00876 , A61B2017/2212 , A61B2017/2215 , A61B2090/037
摘要： An embodiment of a medical retrieval device includes a sheath having a proximal end and a distal end, a handle at the proximal end of the sheath, and a basket. The basket has a collapsed position when the basket is within the sheath and collapsed and an expanded position when the basket is positioned beyond the distal end of the sheath and expanded. The basket includes a plurality of legs, at least one leg having a frangible portion wherein the at least one leg breaks upon application of a predetermined force to the basket. A distal portion of the plurality of legs may be formed from a single piece of material.
摘要翻译：医疗检索装置的实施例包括具有近端和远端的护套，护套的近端处的手柄和筐。当篮子在护套内并且塌缩时，筐具有折叠位置，并且当筐定位在护套的远端并膨胀时，该筐具有折叠位置。篮子包括多个腿部，至少一个腿部具有易碎部分，其中至少一个腿部在向篮子施加预定的力时断裂。多个腿的远侧部分可以由单个材料形成。

7. 发明授权

US06841557B2 Compounds for the treatment of addictive disorders 失效
标题翻译：用于治疗成瘾性疾病的化合物
公开(公告)号：US06841557B2
公开(公告)日：2005-01-11
申请号：US09929666
申请日：2001-08-14
申请人： Richard W. Anderson , Sylvia S. McBrinn , David W. Robertson , Robert C. Marshall
发明人： Richard W. Anderson , Sylvia S. McBrinn , David W. Robertson , Robert C. Marshall
IPC分类号： A61K31/4745 , A61K31/35 , A61K31/38 , A61K31/451 , A61K31/48 , A61K31/497 , A61K31/498 , A61P25/30 , A61P25/32 , A61P25/34 , A61K31/44
CPC分类号： A61K31/48 , A61K31/35 , A61K31/38 , A61K31/451 , A61K31/4745 , A61K31/498
摘要： The treatment of addictive disorders, psychoactive substance use disorders, intoxication disorders, inhalation disorders, alcohol addiction, tobacco addiction, and nicotine addiction using a heterocyclic amine, a phenylazacycloalkane, a cabergoline, or an aromatic bicyclic amine active agent, or a pharmaceutically acceptable derivative or salt of any said active agent is described herein.
摘要翻译：使用杂环胺，苯基氮杂环烷烃，卡麦角林或芳香族双环胺活性剂的治疗上瘾性疾病，精神活性物质使用障碍，中毒障碍，吸入障碍，酒精成瘾，烟草成瘾和尼古丁成瘾，或药学上可接受的衍生物或任何所述活性剂的盐。

8. 发明授权

US5135947A 1-phenyl-3-naphthalenyloxypropanamines and their use as selective serotonin reuptake inhibitors 失效
标题翻译： 1-苯基-3-萘氧基丙胺及其作为选择性5-羟色胺再摄取抑制剂的用途
公开(公告)号：US5135947A
公开(公告)日：1992-08-04
申请号：US561492
申请日：1990-08-01
申请人： David W. Robertson , David T. Wong , Dennis C. Thompson
发明人： David W. Robertson , David T. Wong , Dennis C. Thompson
IPC分类号： C07D317/58
CPC分类号： C07D317/58
摘要： The present invention provides 1-phenyl-3-naphthalenyloxypropanamines which are selective inhibitors of serotonin uptake.
摘要翻译：本发明提供作为5-羟色胺摄取的选择性抑制剂的1-苯基-3-萘氧基丙胺。

9. 发明授权

US5043341A N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides 失效
标题翻译： N-（2-羟基环戊基）-1-异丙基-6-甲基麦角灵-8-甲酰胺
公开(公告)号：US5043341A
公开(公告)日：1991-08-27
申请号：US508324
申请日：1990-04-11
申请人： Marlene L. Cohen , David W. Robertson
发明人： Marlene L. Cohen , David W. Robertson
IPC分类号： A61K31/48 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P25/04 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P43/00 , C07D457/06
CPC分类号： C07D457/06
摘要： This invention provides N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides useful for blocking 5HT.sub.2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.

10. 发明授权

US4996235A 3,4-diphenylbutanamines 失效
标题翻译： 3,4-二苯基丁胺
公开(公告)号：US4996235A
公开(公告)日：1991-02-26
申请号：US125512
申请日：1987-11-25
申请人： David W. Robertson , David T. Wong
发明人： David W. Robertson , David T. Wong
IPC分类号： A61K31/135 , A61P3/04 , A61P25/04 , A61P25/24 , A61P25/26 , A61P25/28 , A61P39/02 , A61P43/00 , C07B61/00 , C07C67/00 , C07C209/00 , C07C209/04 , C07C209/08 , C07C209/16 , C07C209/28 , C07C209/50 , C07C209/62 , C07C211/00 , C07C211/27 , C07C211/29 , C07C211/63 , C07C213/02 , C07C217/56
CPC分类号： C07C211/00 , Y10S514/811
摘要： The present invention provides 3,4-diphenylbutanamines capable of selectively inhibiting the uptake of serotonin and norepinephrine.

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