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1. 发明授权

US09642568B2 Orthogonally redundant sensor systems and methods 有权
公开(公告)号：US09642568B2
公开(公告)日：2017-05-09
申请号：US13478420
申请日：2012-05-23
申请人： Rajiv Shah , Jesper Svenning Kristensen , Katherine T. Wolfe , Soren Aasmul , Anubhuti Bansal
发明人： Rajiv Shah , Jesper Svenning Kristensen , Katherine T. Wolfe , Soren Aasmul , Anubhuti Bansal
IPC分类号： A61B5/1455 , A61B5/1459 , A61B5/00 , A61B5/145 , A61B5/1473 , G01N21/64 , G01N21/77 , G01N33/66
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/14556 , A61B5/1459 , A61B5/1473 , A61B5/4839 , A61B5/6848 , A61B5/6849 , A61B5/742 , A61M5/1723 , A61M2230/201 , G01N21/6408 , G01N21/6428 , G01N21/7703 , G01N33/66 , G01N2021/6441 , G01N2021/6484 , G01N2021/772 , G01N2021/7733 , G01N2021/775 , G01N2021/7759 , G01N2021/7786 , G01N2333/4724
摘要： A continuous glucose monitoring system may include a hand-held monitor, a transmitter, an insulin pump, and an orthogonally redundant glucose sensor, which may comprise an optical glucose sensor and a non-optical glucose sensor. The former may be a fiber optical sensor, including a competitive glucose binding affinity assay with a glucose analog and a fluorophore-labeled glucose receptor, which is interrogated by an optical interrogating system, e.g., a stacked planar integrated optical system. The non-optical sensor may be an electrochemical sensor having a plurality of electrodes distributed along the length thereof. Proximal portions of the optical and electrochemical sensors may be housed inside the transmitter and operationally coupled with instrumentation for, e.g., receiving signals from the sensors, converting to respective glucose values, and communicating the glucose values. The sensors' distal portions may be inserted into a user's body via a single delivery needle and may be co-located inside the user's body.

2. 发明申请

US20100006773A1 Method and apparatus for measuring the phase shift induced in a light signal by a sample 有权
标题翻译：用于测量由样品在光信号中感应的相移的方法和装置
公开(公告)号：US20100006773A1
公开(公告)日：2010-01-14
申请号：US12457074
申请日：2009-06-01
申请人： Soren Aasmul
发明人： Soren Aasmul
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , G01J3/4406 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N27/3271 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
摘要： A first light source emits a light signal along a measurement optical path that includes a sample and a second light source emits a light signal along a dummy measurement optical path. A measurement circuit receives the light signals and provides outputs separated in time which are indicative of the phase of the respective light signals. A phase shift is induced in light in the measurement optical path by the sample. A reference circuit receives a signal indicative of the phase of the light signals emitted by the first and second light sources. Circuitry compares the phases of light output from the two circuits to provide output indicative of a first measured phase difference during operation of the first light source. Correction is applied to this measurement by taking a similar phase difference measurement during operation of the second light source and comparing the two phase differences.
摘要翻译：第一光源沿着包括样本的测量光路发射光信号，并且第二光源沿着虚拟测量光路发射光信号。测量电路接收光信号并提供时间上分离的指示各个光信号的相位的输出。通过样品在测量光路中的光中引起相移。参考电路接收指示由第一和第二光源发射的光信号的相位的信号。电路比较来自两个电路的光输出的相位，以在第一光源的操作期间提供指示第一测量相位差的输出。通过在第二光源的操作期间进行相似的相位差测量并比较两个相位差，对该测量进行校正。

3. 发明申请

US20070153279A1 Fluorometers 有权
标题翻译：荧光计
公开(公告)号：US20070153279A1
公开(公告)日：2007-07-05
申请号：US10584294
申请日：2004-12-20
申请人： Soren Aasmul
发明人： Soren Aasmul
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01J1/04 , G01J1/0422 , G01N2021/6463 , G01N2201/0636
摘要： In apparatus for the production and detection of fluorescence at a sample surface, the height of the apparatus above the sample surface is reduced, and loss of the emitted fluorescence due to reflection loss and light scattering is minimized. The apparatus comprises a three-dimensionally curved light reflecting surface (40) that directs light from a light source (32) transversely to its original path and focuses the light on to an illumination zone (30) at or below the sample surface. The reflecting surface (40) also collects, directs and at least partially collimates emitted fluorescence transversely to its original path and towards a detector (46).
摘要翻译：在用于在样品表面生产和检测荧光的装置中，样品表面上方的装置的高度减小，并且由于反射损失和光散射引起的发射的荧光的损失最小化。该装置包括三维弯曲的光反射表面（40），其将来自光源（32）的光横向于其原始路径引导并将光聚焦到在样品表面处或下方的照明区域（30）。反射表面（40）还收集，引导并至少部分地将发射的荧光横向于其原始路径并朝向检测器（46）准直。

4. 发明申请

US20050197621A1 Method and a system for assisting a user in a medical self treatment, said self treatment comprising a plurality of actions 审中-公开
标题翻译：方法和用于辅助用户进行医疗自我治疗的系统，所述自我治疗包括多个动作
公开(公告)号：US20050197621A1
公开(公告)日：2005-09-08
申请号：US10664368
申请日：2003-09-17
申请人： Jens Poulsen , Lars Christensen , Soren Aasmul
发明人： Jens Poulsen , Lars Christensen , Soren Aasmul
IPC分类号： A61B5/00 , A61M5/00 , G06F19/00 , G06Q50/24 , G11C11/00 , A61M31/00 , G01N33/48 , G01N33/50
CPC分类号： G06Q50/24 , A61B5/0002 , A61B5/14532 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61M5/003 , A61M5/24 , A61M2205/505 , A61M2205/52 , G06F19/325 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/50 , Y10S128/92 , Y10S128/921
摘要： This invention relates to a method of assisting a user in a medical self treatment, said self treatment comprising a plurality of actions, said method comprising the steps of collecting in a one or more databases data representing values of parameters relevant for said self treatment, and the step of processing said one or more databases to provide for alternative choices between two or more action and a corresponding value for each two or more actions. The invention also relates to a computer system having means for performing the method according to the invention, and a computer readable medium having a program recorded thereon, where the program when executed is to make the computer execute the method according to the invention
摘要翻译：本发明涉及一种帮助用户进行医疗自我治疗的方法，所述自我治疗包括多个动作，所述方法包括以下步骤：在一个或多个数据库中收集表示与所述自我治疗相关的参数值的数据，以及处理所述一个或多个数据库以提供两个或多个动作之间的替代选择和每个两个或多个动作的对应值的步骤。本发明还涉及具有用于执行根据本发明的方法的装置的计算机系统和其上记录有程序的计算机可读介质，其中执行时的程序是使计算机执行根据本发明的方法

5. 发明授权

US06585699B2 Drug delivery device provided with a one-way mechanism 有权
公开(公告)号：US06585699B2
公开(公告)日：2003-07-01
申请号：US09822162
申请日：2001-03-30
申请人： Henrik Ljunggreen , Jens Ulrik Poulsen , Soren Aasmul , Lars Hofmann Christensen , Jens Moller-Jensen , Peter Moller-Jensen
发明人： Henrik Ljunggreen , Jens Ulrik Poulsen , Soren Aasmul , Lars Hofmann Christensen , Jens Moller-Jensen , Peter Moller-Jensen
IPC分类号： A61M528
CPC分类号： A61M5/31511 , A61M5/31501 , A61M5/31543 , A61M5/3156 , A61M5/31585 , A61M5/31593 , A61M2005/31518 , A61M2005/31588
摘要： A drug delivery device comprising a housing (1) with a drug container (2) being provided with delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2). The housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2) and rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism. The one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.

6. 发明授权

US08080810B2 Method and apparatus for measuring the phase shift iduced in a light signal by a sample 有权
公开(公告)号：US08080810B2
公开(公告)日：2011-12-20
申请号：US12929073
申请日：2010-12-29
申请人： Soren Aasmul
发明人： Soren Aasmul
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , G01J3/4406 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N27/3271 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
摘要： A first light source emits a light signal along a measurement optical path that includes a sample and a second light source emits a light signal along a dummy measurement optical path. A measurement circuit receives the light signals and provides outputs separated in time which are indicative of the phase of the respective light signals. A phase shift is induced in light in the measurement optical path by the sample. A reference circuit receives a signal indicative of the phase of the light signals emitted by the first and second light sources. Circuitry compares the phases of light output from the two circuits to provide output indicative of a first measured phase difference during operation of the first light source. Correction is applied to this measurement by taking a similar phase difference measurement during operation of the second light source and comparing the two phase differences.

7. 发明授权

US07884338B2 Method and apparatus for measuring the phase shift induced in a light signal by a sample 有权
标题翻译：用于测量由样品在光信号中感应的相移的方法和装置
公开(公告)号：US07884338B2
公开(公告)日：2011-02-08
申请号：US12457074
申请日：2009-06-01
申请人： Soren Aasmul
发明人： Soren Aasmul
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , G01J3/4406 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N27/3271 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
摘要： A first light source emits a light signal along a measurement optical path that includes a sample and a second light source emits a light signal along a dummy measurement optical path. A measurement circuit receives the light signals and provides outputs separated in time which are indicative of the phase of the respective light signals. A phase shift is induced in light in the measurement optical path by the sample. A reference circuit receives a signal indicative of the phase of the light signals emitted by the first and second light sources. Circuitry compares the phases of light output from the two circuits to provide output indicative of a first measured phase difference during operation of the first light source. Correction is applied to this measurement by taking a similar phase difference measurement during operation of the second light source and comparing the two phase differences.
摘要翻译：第一光源沿着包括样本的测量光路发射光信号，并且第二光源沿着虚拟测量光路发射光信号。测量电路接收光信号并提供时间上分离的指示相应光信号的相位的输出。通过样品在测量光路中的光中引起相移。参考电路接收指示由第一和第二光源发射的光信号的相位的信号。电路比较来自两个电路的光输出的相位，以在第一光源的操作期间提供指示第一测量相位差的输出。通过在第二光源的操作期间进行相似的相位差测量并比较两个相位差，对该测量进行校正。

8. 发明申请

US20070293742A1 Medical System And A Method Of Controlling The System For Use By A Patient For Medical Self Treatment 审中-公开
标题翻译：医疗系统和一种用于医疗自我治疗的病人使用系统的方法
公开(公告)号：US20070293742A1
公开(公告)日：2007-12-20
申请号：US11846028
申请日：2007-08-28
申请人： Jan Simonsen , Jens Poulsen , Kent Rokkjaer , Lars Christensen , Soren Aasmul , Steffen Lav
发明人： Jan Simonsen , Jens Poulsen , Kent Rokkjaer , Lars Christensen , Soren Aasmul , Steffen Lav
IPC分类号： A61B5/00
CPC分类号： A61M5/31546 , A61B5/14532 , A61B5/150022 , A61B5/150267 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/15113 , A61B5/157 , A61B5/7264 , A61M5/24 , A61M5/31525 , A61M5/31553 , A61M2205/3584 , A61M2205/3592 , G16H20/17 , G16H40/63
摘要： This invention relates to an system for self treatment. The system consists of several portable modules where one of the modules is designated as a master module. The master module controls, supervises and monitors all the mutual information and data exchange between itself and the rest of the modules. The modules can e.g. consist of a BGM, a doser and a storage container. The modules may be able to generate and store data which is transmitted to the master module if it is within range. If the master module is not within range, the data is kept locally in the module until the master module is available. The master module can send the data to an external unit like a computer or database for further processing. A physician or an expert care-team can access the data in the database and give guidance to the patient on the basis of these processed data. This processing could also be done automatically by utilization of an expert system.
摘要翻译：本发明涉及一种用于自我治疗的系统。该系统由几个便携式模块组成，其中一个模块被指定为主模块。主模块控制，监督和监视其本身与其余模块之间的所有互信息和数据交换。模块可以例如由BGM，加料器和储存容器组成。如果模块在范围内，则可以生成并存储发送到主模块的数据。如果主模块不在范围内，则数据将保留在模块本地，直到主模块可用。主模块可以将数据发送到外部单元，如计算机或数据库进行进一步处理。医生或专家护理团队可以访问数据库中的数据，并根据这些处理的数据对患者进行指导。这种处理也可以通过利用专家系统自动完成。

9. 发明申请

US20080024779A1 Method and Apparatus for Measuring the Phase Shift Induced in a Light Signal by a Sample 有权
标题翻译：用于测量由样品引起的光信号中的相移的方法和装置
公开(公告)号：US20080024779A1
公开(公告)日：2008-01-31
申请号：US11658263
申请日：2005-07-27
申请人： Soren Aasmul
发明人： Soren Aasmul
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , G01J3/4406 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N27/3271 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
摘要： Apparatus for measuring a phase shift induced in a light signal has a first light source for emitting a light signal along a measurement optical path that includes a sample, for example a fluorescent sample, and a second light source for emitting a light signal along a dummy measurement optical path. A measurement electronic circuit is provided for receiving the light signals and providing outputs separated in time which are indicative of the phase of the respective light signals. In use, a phase shift is induced in light in the measurement optical path by the fluorescent sample. A reference electronic circuit is provided for receiving a signal indicative of the phase of the light signals emitted by the first and second light sources. Circuitry is provided to compare the respective phases of light output from the two circuits to provide an output indicative of a first measured phase difference during operation of the first light source. A correction is then applied to this measurement by taking a similar phase difference measurement during operation of the second light source and comparing the two phase differences.
摘要翻译：用于测量在光信号中感应的相移的装置具有第一光源，用于沿着包括样品例如荧光样品的测量光路发射光信号，以及用于沿虚拟物发射光信号的第二光源测量光路。提供了一种测量电子电路，用于接收光信号并提供时间上分离的表示各个光信号的相位的输出。在使用中，通过荧光样品在测量光路中的光中引起相移。提供参考电子电路用于接收指示由第一和第二光源发射的光信号的相位的信号。提供电路以比较来自两个电路的光输出的各个相位，以提供指示在第一光源的操作期间的第一测量相位差的输出。然后通过在第二光源的操作期间进行类似的相位差测量并比较两个相位差来对该测量进行校正。

10. 发明授权

US07282029B1 Method and a system for assisting a user in a medical self treatment, said self treatment comprising a plurality of actions 有权
标题翻译：方法和用于辅助用户进行医疗自我治疗的系统，所述自我治疗包括多个动作
公开(公告)号：US07282029B1
公开(公告)日：2007-10-16
申请号：US10663463
申请日：2003-09-16
申请人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Soren Aasmul
发明人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Soren Aasmul
IPC分类号： A61B5/00
CPC分类号： G06Q50/24 , A61B5/0002 , A61B5/14532 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61M5/003 , A61M5/24 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06F19/325 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/50 , Y10S128/92 , Y10S128/921
摘要： A method of self treating a disease, such as diabetes, includes collecting in one or more databases data representing values of parameters that related to the self treatment. The data is processed to provide a plurality of alternate choices between two or more actions that may be taken and a corresponding value for each action is calculated. A computerized system may be employed to perform the above method and the system may include a computer readable medium for executing the method.
摘要翻译：自我治疗疾病如糖尿病的方法包括在一个或多个数据库中收集表示与自身治疗相关的参数值的数据。处理数据以在可以采取的两个或多个动作之间提供多个替代选择，并计算每个动作的相应值。可以采用计算机化系统来执行上述方法，并且系统可以包括用于执行该方法的计算机可读介质。

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